Fusions

Summaries of gene fusions and their clinical relevance.

Back to Open Access Summaries
Need updated, customized, evidence‑backed summaries? Get it from the leaders in AI‑powered, evidence‑backed summaries provider.
Contact us
Fusion Disease Driver/Marker Power Therapeutic Actionability Prognostic Impact Diagnostic Specificity Monitoring Utility Actions
KAT6B–OPN1LW
(HGNC:17582, HGNC:9936)
weak weak weak weak weak
PLA2G15–NFATC3
(HGNC:17163, HGNC:7777)
leukemia
(MONDO_0005059)
 strong weak strong moderate weak
STARD3–PPP1R1B
(HGNC:17579, HGNC:9287)
MONDO:0001056
(MONDO:0001056)
 strong strong moderate strong weak
ERC1–RET
(HGNC:17072, HGNC:9967)
MONDO:0005075
(MONDO:0005075)
 strong strong moderate moderate weak
ARHGAP26–CLDN18
(HGNC:17073, HGNC:2039)
MONDO:0004992
(MONDO:0004992)
 strong strong moderate strong weak
MEAF6–SUZ12
(HGNC:25674, HGNC:17101)
MONDO:0006745
(MONDO:0006745)
 moderate weak weak moderate weak
CD74–NRG1
(HGNC:1697, HGNC:7997)
lung adenocarcinoma
(MONDO_0005061)
 strong strong moderate strong weak
ERC1–FGFR2
(HGNC:17072, HGNC:3689)
MONDO:0005061
(MONDO:0005061)
 strong moderate moderate moderate weak
HNRNPUL1–MEF2D
(HGNC:17011, HGNC:6997)
MONDO:0004967
(MONDO:0004967)
 strong strong strong moderate weak
ZMYND11–MBTD1
(HGNC:16966, HGNC:19866)
childhood acute myeloid leukemia
(MONDO_0004996)
 strong weak moderate moderate weak
SEC31A–ALK
(HGNC:17052, HGNC:427)
inflammatory myofibroblastic tumor
(MONDO_0015798)
 strong strong moderate strong weak
CEP43–FGFR1
(HGNC:17012, HGNC:3688)
acquired polycythemia vera
(MONDO_0009891)
 moderate weak moderate moderate weak
MLLT11–KMT2A
(HGNC:16997, HGNC:7132)
MONDO:0005059
(MONDO:0005059)
 strong weak moderate strong weak
CD28–CTLA4
(HGNC:1653, HGNC:2505)
MONDO:0015758
(MONDO:0015758)
 strong strong moderate strong weak
FBXW7–NOTCH1
(HGNC:16712, HGNC:7881)
T-cell acute lymphoblastic leukemia
(MONDO_0004963)
 weak weak weak weak weak
CD47–MET
(HGNC:1682, HGNC:7029)
non-small cell lung carcinoma
(MONDO_0005233)
 strong strong moderate strong weak
ETV6–ACSL6
(HGNC:3495, HGNC:16496)
myeloproliferative neoplasm
(MONDO_0020076)
 strong moderate strong moderate weak
CARD11–PIK3R3
(HGNC:16393, HGNC:8981)
hematopoietic and lymphoid system neoplasm
(MONDO_0002334)
 strong strong moderate strong weak
SLC45A2–AMACR
(HGNC:16472, HGNC:451)
liver cancer
(MONDO_0002691)
 strong strong moderate moderate weak
TRIM33–RET
(HGNC:16290, HGNC:9967)
MONDO:0005192
(MONDO:0005192)
 moderate moderate weak moderate weak
Showing 281–300 of 512