Variant Synonymizer: Platform to identify mutations defined in different ways is available now!

VarSy

Over 2,000 gene–disease validation summaries are now available—no login required!

Browse Summaries

Stats

Total associations
6575
Unique genes
4162
Unique diseases
3283

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Gene Disease Score Actions
GRK1
(HGNC:10013)
Oguchi disease
(MONDO_0019152)
Strong
RNASE1
(HGNC:10044)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
RING1
(HGNC:10018)
leukemia
(MONDO_0005059)
Limited
RNF4
(HGNC:10067)
Prader-Willi syndrome
(MONDO_0008300)
Limited
RNASE3
(HGNC:10046)
asthma
(MONDO_0004979)
Strong
RNASE4
(HGNC:10047)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
RNF7
(HGNC:10070)
Oguchi disease
(MONDO_0019152)
Strong
RNMT
(HGNC:10075)
colorectal cancer
(MONDO_0005575)
Limited
ROR1
(HGNC:10256)
B-cell chronic lymphocytic leukemia
(MONDO_0004948)
Strong
BDH1
(HGNC:1027)
chromosome 3q29 microduplication syndrome
(MONDO_0012761)
Moderate
TRIM10
(HGNC:10072)
Parkinson disease
(MONDO_0005180)
Moderate
RPL15
(HGNC:10306)
Diamond-Blackfan anemia
(MONDO_0015253)
Moderate
RPL18
(HGNC:10310)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RPL17
(HGNC:10307)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RPL8
(HGNC:10368)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RPS17
(HGNC:10397)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RPS29
(HGNC:10419)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RPS7
(HGNC:10440)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RPS28
(HGNC:10418)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RRAD
(HGNC:10446)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
RTN2
(HGNC:10468)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
S100A2
(HGNC:10492)
colorectal cancer
(MONDO_0005575)
Limited
RTN3
(HGNC:10469)
Alzheimer disease
(MONDO_0004975)
Limited
RRAD
(HGNC:10446)
Brugada syndrome
(MONDO_0015263)
Strong
S100P
(HGNC:10504)
lung cancer
(MONDO_0008903)
Strong
SALL2
(HGNC:10526)
nephrotic syndrome
(MONDO_0005377)
Limited
SC5D
(HGNC:10547)
lathosterolosis
(MONDO_0011816)
Strong
SARS1
(HGNC:10537)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
STMN2
(HGNC:10577)
osteoarthritis
(MONDO_0005178)
Limited
CLEC11A
(HGNC:10576)
acute myeloid leukemia
(MONDO_0018874)
Strong
SALL2
(HGNC:10526)
Alport syndrome
(MONDO_0018965)
Limited
CNNM4
(HGNC:105)
Jalili syndrome
(MONDO_0009007)
Strong
SCML2
(HGNC:10581)
Nance-Horan syndrome
(MONDO_0010545)
Disputed
SAR1B
(HGNC:10535)
chylomicron retention disease
(MONDO_0009528)
Strong
BLMH
(HGNC:1059)
Alzheimer disease
(MONDO_0004975)
Limited
SERF1A
(HGNC:10755)
spinal muscular atrophy
(MONDO_0001516)
Limited
SDC3
(HGNC:10660)
obesity disorder
(MONDO_0011122)
Limited
BMP8B
(HGNC:1075)
premature menopause
(MONDO_0001119)
Limited
SEMA3B
(HGNC:10724)
schizophrenia
(MONDO_0005090)
Limited
SF3A1
(HGNC:10765)
colorectal cancer
(MONDO_0005575)
Limited
CCL19
(HGNC:10617)
tuberculosis
(MONDO_0018076)
Limited
SF3B2
(HGNC:10769)
craniofacial microsomia
(MONDO_0015397)
Strong
SETMAR
(HGNC:10762)
acute myeloid leukemia
(MONDO_0018874)
Strong
SHMT2
(HGNC:10852)
neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities
(MONDO_0030866)
Strong
SRSF5
(HGNC:10787)
bipolar disorder
(MONDO_0004985)
Moderate
SI
(HGNC:10856)
congenital sucrase-isomaltase deficiency
(MONDO_0009114)
Strong
SKP1
(HGNC:10899)
breast cancer
(MONDO_0007254)
Limited
SHOX2
(HGNC:10854)
atrial fibrillation
(MONDO_0004981)
Strong
ST3GAL5
(HGNC:10872)
GM3 synthase deficiency
(MONDO_0018274)
Strong
CCL1
(HGNC:10609)
chronic obstructive pulmonary disease
(MONDO_0005002)
Limited
SLC25A10
(HGNC:10980)
mitochondrial DNA depletion syndrome
(MONDO_0018158)
Moderate
SLC12A7
(HGNC:10915)
congenital hydrocephalus
(MONDO_0016349)
Limited
SLC24A1
(HGNC:10975)
congenital stationary night blindness
(MONDO_0016293)
Strong
SLC2A5
(HGNC:11010)
hereditary fructose intolerance
(MONDO_0009249)
Refuted
SLC32A1
(HGNC:11018)
generalized epilepsy with febrile seizures plus
(MONDO_0018214)
Strong
SLC30A3
(HGNC:11014)
schizophrenia
(MONDO_0005090)
Strong
SLC8A2
(HGNC:11069)
gastric cancer
(MONDO_0001056)
Limited
SLC35A1
(HGNC:11021)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
SMARCC2
(HGNC:11105)
Coffin-Siris syndrome
(MONDO_0015452)
Strong
SIGLEC1
(HGNC:11127)
pancreatic ductal adenocarcinoma
(MONDO_0005184)
Limited
SLC6A6
(HGNC:11052)
dilated cardiomyopathy
(MONDO_0005021)
Strong
SLPI
(HGNC:11092)
breast cancer
(MONDO_0007254)
Strong
SNAP29
(HGNC:11133)
CEDNIK syndrome
(MONDO_0012290)
Strong
SNCB
(HGNC:11140)
Lewy body dementia
(MONDO_0007488)
Strong
SMARCD3
(HGNC:11108)
plasma cell myeloma
(MONDO_0009693)
Strong
SNAPC4
(HGNC:11137)
ankylosing spondylitis
(MONDO_0005306)
Limited
FSCN1
(HGNC:11148)
breast cancer
(MONDO_0007254)
Strong
FSCN1
(HGNC:11148)
autism
(MONDO_0005260)
Limited
SNRNP70
(HGNC:11150)
mixed connective tissue disease
(MONDO_0005854)
Strong
SNRPB
(HGNC:11153)
neurodevelopmental disorder
(MONDO_0700092)
Limited
SNRPB
(HGNC:11153)
cerebrocostomandibular syndrome
(MONDO_0007301)
Strong
SOX18
(HGNC:11194)
hypotrichosis-lymphedema-telangiectasia syndrome
(MONDO_0011914)
Strong
SPAG6
(HGNC:11215)
male infertility
(MONDO_0005372)
Limited
SNRPF
(HGNC:11162)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
SPARCL1
(HGNC:11220)
corneal dystrophy
(MONDO_0018102)
Strong
SPIB
(HGNC:11242)
primary biliary cholangitis
(MONDO_0005388)
Strong
SPAG6
(HGNC:11215)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
SPRR2B
(HGNC:11262)
asthma
(MONDO_0004979)
Strong
SPON1
(HGNC:11252)
schizophrenia
(MONDO_0005090)
Limited
SRP72
(HGNC:11303)
aplastic anemia
(MONDO_0015909)
Strong
SRP72
(HGNC:11303)
myelodysplastic syndrome
(MONDO_0018881)
Limited
SPRR2B
(HGNC:11262)
atopic eczema
(MONDO_0004980)
Strong
SRPK2
(HGNC:11306)
congenital heart disease
(MONDO_0005453)
Disputed
SRPK2
(HGNC:11306)
atrial septal defect
(MONDO_0006664)
Limited
SRP72
(HGNC:11303)
acute myeloid leukemia
(MONDO_0018874)
Strong
SSR4
(HGNC:11326)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
SSR3
(HGNC:11325)
congenital disorder of glycosylation
(MONDO_0015286)
Limited
SSX1
(HGNC:11335)
synovial sarcoma
(MONDO_0010434)
Strong
SS18
(HGNC:11340)
synovial sarcoma
(MONDO_0010434)
Strong
STK24
(HGNC:11403)
keratoconus
(MONDO_0015486)
Limited
SRPK3
(HGNC:11402)
X-linked intellectual disability
(MONDO_0100284)
Strong
SUCLG2
(HGNC:11450)
multiple acyl-CoA dehydrogenase deficiency
(MONDO_0009282)
Moderate
STX3
(HGNC:11438)
microvillus inclusion disease
(MONDO_0009635)
Strong
STX16
(HGNC:11431)
pseudohypoparathyroidism
(MONDO_0019992)
Strong
VAMP7
(HGNC:11486)
Rett syndrome
(MONDO_0010726)
Limited
TAF6
(HGNC:11540)
Wiedemann-Steiner syndrome
(MONDO_0011518)
Moderate
SVIL
(HGNC:11480)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
TALDO1
(HGNC:11559)
transaldolase deficiency
(MONDO_0011624)
Strong
TAF6
(HGNC:11540)
Cornelia de Lange syndrome
(MONDO_0016033)
Moderate
TBX19
(HGNC:11596)
congenital isolated adrenocorticotropic hormone deficiency
(MONDO_0008720)
Strong
ELOC
(HGNC:11617)
clear cell renal carcinoma
(MONDO_0005005)
Limited
TCP11
(HGNC:11658)
inflammatory bowel disease
(MONDO_0005265)
Limited
ELOC
(HGNC:11617)
von Hippel-Lindau disease
(MONDO_0008667)
Moderate
TEC
(HGNC:11719)
systemic lupus erythematosus
(MONDO_0007915)
Moderate
TEC
(HGNC:11719)
rheumatoid arthritis
(MONDO_0008383)
Limited
DAGLA
(HGNC:1165)
attention deficit-hyperactivity disorder
(MONDO_0007743)
Limited
TFCP2
(HGNC:11748)
Alzheimer disease
(MONDO_0004975)
Disputed
TFDP2
(HGNC:11751)
chronic kidney disease
(MONDO_0005300)
Strong
MRPL49
(HGNC:1176)
combined oxidative phosphorylation deficiency
(MONDO_0000732)
Strong
TGM5
(HGNC:11781)
acral peeling skin syndrome
(MONDO_0012345)
Strong
THBS3
(HGNC:11787)
gastric cancer
(MONDO_0001056)
Moderate
TGM3
(HGNC:11779)
uncombable hair syndrome
(MONDO_0008621)
Strong
TLL2
(HGNC:11844)
spinal muscular atrophy
(MONDO_0001516)
Limited
ANO2
(HGNC:1183)
panic disorder
(MONDO_0005383)
Limited
NPAP1
(HGNC:1190)
Prader-Willi syndrome
(MONDO_0008300)
Limited
TNP2
(HGNC:11952)
male infertility
(MONDO_0005372)
Limited
FERRY3
(HGNC:1184)
intellectual disability
(MONDO_0001071)
Strong
TOMM70
(HGNC:11985)
mitochondrial disease
(MONDO_0044970)
Moderate
TNP2
(HGNC:11952)
azoospermia
(MONDO_0100459)
Disputed
BHLHE22
(HGNC:11963)
Glanzmann thrombasthenia
(MONDO_0100326)
Strong
TPO
(HGNC:12015)
congenital hypothyroidism
(MONDO_0018612)
Limited
TOMM70
(HGNC:11985)
COVID-19
(MONDO_0100096)
Limited
CEP41
(HGNC:12370)
Joubert syndrome
(MONDO_0018772)
Strong
TSHB
(HGNC:12372)
central congenital hypothyroidism
(MONDO_0016410)
Strong
LDLRAD4
(HGNC:1224)
periodontitis
(MONDO_0005076)
Strong
TSHB
(HGNC:12372)
congenital hypothyroidism
(MONDO_0018612)
Strong
TUBG2
(HGNC:12419)
polymicrogyria
(MONDO_0000087)
Limited
TTC3
(HGNC:12393)
Alzheimer disease
(MONDO_0004975)
Strong
UBAP1
(HGNC:12461)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
C1R
(HGNC:1246)
Ehlers-Danlos syndrome, periodontitis type
(MONDO_0007527)
Strong
UBA7
(HGNC:12471)
Crohn disease
(MONDO_0005011)
Limited
UBA7
(HGNC:12471)
intellectual disability
(MONDO_0001071)
Moderate
C1S
(HGNC:1247)
systemic lupus erythematosus
(MONDO_0007915)
Strong
UBA7
(HGNC:12471)
ulcerative colitis
(MONDO_0005101)
Limited
UBE2H
(HGNC:12484)
Parkinson disease
(MONDO_0005180)
Limited
UBE4A
(HGNC:12499)
intellectual disability
(MONDO_0001071)
Strong
UCN
(HGNC:12516)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
UBE2N
(HGNC:12492)
breast cancer
(MONDO_0007254)
Limited
UFD1
(HGNC:12520)
schizophrenia
(MONDO_0005090)
Limited
ACP5
(HGNC:124)
Spondyloenchondrodysplasia with immune dysregulation
(MONDO_0011939)
Strong
UGP2
(HGNC:12527)
glycogen storage disease II
(MONDO_0009290)
Limited
UNC119
(HGNC:12565)
cone-rod dystrophy
(MONDO_0015993)
Limited
USP14
(HGNC:12612)
neurodevelopmental disorder
(MONDO_0700092)
Strong
USP2
(HGNC:12618)
intellectual disability
(MONDO_0001071)
Limited
USP28
(HGNC:12625)
glioma
(MONDO_0021042)
Strong
USP28
(HGNC:12625)
breast cancer
(MONDO_0007254)
Strong
VAMP5
(HGNC:12646)
Hirschsprung disease
(MONDO_0018309)
Strong
USP6
(HGNC:12629)
aneurysmal bone cyst
(MONDO_0018815)
Strong
VDAC3
(HGNC:12674)
autism spectrum disorder
(MONDO_0005258)
Limited
VPREB1
(HGNC:12709)
B-cell acute lymphoblastic leukemia
(MONDO_0004947)
Strong
WASL
(HGNC:12735)
gastric cancer
(MONDO_0001056)
Limited
ACR
(HGNC:126)
Phelan-McDermid syndrome
(MONDO_0011652)
Limited
WDR3
(HGNC:12755)
differentiated thyroid carcinoma
(MONDO_0015447)
Strong
WDR4
(HGNC:12756)
isolated growth hormone deficiency type IA
(MONDO_0009876)
Limited
TSPEAR
(HGNC:1268)
ectodermal dysplasia syndrome
(MONDO_0019287)
Strong
LAT2
(HGNC:12749)
Williams syndrome
(MONDO_0008678)
Limited
WNT8B
(HGNC:12789)
bladder exstrophy
(MONDO_0010805)
Limited
XPOT
(HGNC:12826)
12q14 microdeletion syndrome
(MONDO_0019784)
Limited
REXO4
(HGNC:12820)
familial isolated pituitary adenoma
(MONDO_0017824)
Limited
XPNPEP2
(HGNC:12823)
premature menopause
(MONDO_0001119)
Limited
WNT6
(HGNC:12785)
bladder exstrophy
(MONDO_0010805)
Limited
YWHAH
(HGNC:12853)
schizophrenia
(MONDO_0005090)
Limited
ZNF12
(HGNC:12902)
autism
(MONDO_0005260)
Limited
YME1L1
(HGNC:12843)
autism spectrum disorder
(MONDO_0005258)
Limited
ZNF141
(HGNC:12926)
Huntington disease
(MONDO_0007739)
Moderate
XRN2
(HGNC:12836)
autism spectrum disorder
(MONDO_0005258)
Strong
ZBTB16
(HGNC:12930)
acute promyelocytic leukemia
(MONDO_0012883)
Strong
ZNF142
(HGNC:12927)
neurodevelopmental disorder with impaired speech and hyperkinetic movements
(MONDO_0032741)
Strong
TRIM26
(HGNC:12962)
schizophrenia
(MONDO_0005090)
Limited
ZBTB17
(HGNC:12936)
dilated cardiomyopathy
(MONDO_0005021)
Strong
SF1
(HGNC:12950)
multiple endocrine neoplasia type 1
(MONDO_0007540)
Disputed
ZNF182
(HGNC:13001)
intellectual disability
(MONDO_0001071)
Limited
ZNF184
(HGNC:12975)
Parkinson disease
(MONDO_0005180)
Limited
ZNF224
(HGNC:13017)
Alzheimer disease
(MONDO_0004975)
Moderate
ZNF202
(HGNC:12994)
myocardial ischemia
(MONDO_0024644)
Strong
ZMYM5
(HGNC:13029)
intellectual disability
(MONDO_0001071)
Limited
ZNF44
(HGNC:13110)
intellectual disability
(MONDO_0001071)
Limited
ZNF41
(HGNC:13107)
intellectual disability
(MONDO_0001071)
Moderate
ZNF44
(HGNC:13110)
epilepsy
(MONDO_0005027)
Limited
CNBP
(HGNC:13164)
myotonic dystrophy type 2
(MONDO_0011266)
Strong
CNBP
(HGNC:13164)
myotonic dystrophy
(MONDO_0016107)
Strong
ZP2
(HGNC:13188)
female infertility
(MONDO_0021124)
Strong
FTSJ1
(HGNC:13254)
X-linked intellectual disability
(MONDO_0100284)
Strong
ADAMTS10
(HGNC:13201)
Weill-Marchesani syndrome
(MONDO_0018096)
Definitive
CAPN12
(HGNC:13249)
colorectal cancer
(MONDO_0005575)
Strong
CLEC4A
(HGNC:13257)
rheumatoid arthritis
(MONDO_0008383)
Strong
EI24
(HGNC:13276)
osteosarcoma
(MONDO_0009807)
Limited
ECE2
(HGNC:13275)
Alzheimer disease
(MONDO_0004975)
Moderate
NEK8
(HGNC:13387)
nephronophthisis
(MONDO_0019005)
Strong
NAPSA
(HGNC:13395)
lung adenocarcinoma
(MONDO_0005061)
Strong
SLC30A9
(HGNC:1329)
psychomotor regression-oculomotor apraxia-movement disorder-nephropathy syndrome
(MONDO_0044726)
Strong
PBX4
(HGNC:13403)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
PRUNE1
(HGNC:13420)
neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies
(MONDO_0060490)
Strong
ROBO3
(HGNC:13433)
horizontal gaze palsy with progressive scoliosis
(MONDO_0011810)
Definitive
SLITRK2
(HGNC:13449)
neurodevelopmental disorder
(MONDO_0700092)
Strong
UBE3B
(HGNC:13478)
oculocerebrofacial syndrome, Kaufman type
(MONDO_0009485)
Strong
FAM78B
(HGNC:13495)
chronic kidney disease
(MONDO_0005300)
Moderate
UGT2B28
(HGNC:13479)
endometriosis
(MONDO_0005133)
Limited
UGT2B28
(HGNC:13479)
prostate cancer
(MONDO_0008315)
Disputed
FEZF2
(HGNC:13506)
intellectual disability
(MONDO_0001071)
Limited
ATP8B3
(HGNC:13535)
colorectal cancer
(MONDO_0005575)
Limited
ATP9A
(HGNC:13540)
intellectual disability
(MONDO_0001071)
Strong
ATP10B
(HGNC:13543)
Parkinson disease
(MONDO_0005180)
Disputed
ATP10D
(HGNC:13549)
myocardial infarction
(MONDO_0005068)
Strong
IFT122
(HGNC:13556)
cranioectodermal dysplasia
(MONDO_0009032)
Strong
ERLIN2
(HGNC:1356)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
MAGEC2
(HGNC:13574)
melanoma
(MONDO_0005105)
Strong
BRD4
(HGNC:13575)
nut midline carcinoma
(MONDO_0005563)
Strong
FBXL7
(HGNC:13604)
Hennekam syndrome
(MONDO_0016256)
Limited
PABPC5
(HGNC:13629)
attention deficit hyperactivity disorder, inattentive type
(MONDO_0005302)
Limited
PABPC5
(HGNC:13629)
Tourette syndrome
(MONDO_0007661)
Limited
TMEM187
(HGNC:13705)
systemic lupus erythematosus
(MONDO_0007915)
Strong
SCG3
(HGNC:13707)
obesity disorder
(MONDO_0011122)
Moderate
POF1B
(HGNC:13711)
premature menopause
(MONDO_0001119)
Limited
MAEA
(HGNC:13731)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
RELT
(HGNC:13764)
amelogenesis imperfecta
(MONDO_0019507)
Strong
IGDCC4
(HGNC:13770)
age-related macular degeneration
(MONDO_0005150)
Limited
GFM1
(HGNC:13780)
mitochondrial disease
(MONDO_0044970)
Strong
PRX
(HGNC:13797)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
SLCO1C1
(HGNC:13819)
Alzheimer disease
(MONDO_0004975)
Strong
ZNF311
(HGNC:13847)
cancer
(MONDO_0004992)
Limited
SCAND3
(HGNC:13851)
cardiovascular disorder
(MONDO_0004995)
Limited
SCAND3
(HGNC:13851)
hypertensive disorder
(MONDO_0005044)
Limited
CABP4
(HGNC:1386)
congenital stationary night blindness
(MONDO_0016293)
Strong
SGK2
(HGNC:13900)
Shwachman-Diamond syndrome
(MONDO_0009833)
Limited
ABHD16A
(HGNC:13921)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
PRDM12
(HGNC:13997)
channelopathy-associated congenital insensitivity to pain, autosomal recessive
(MONDO_0009459)
Strong
PRDM13
(HGNC:13998)
North Carolina macular dystrophy
(MONDO_0007630)
Definitive
PRDM15
(HGNC:13999)
chronic obstructive pulmonary disease
(MONDO_0005002)
Moderate
MRPL15
(HGNC:14054)
benign essential blepharospasm
(MONDO_0011728)
Limited
SLC5A7
(HGNC:14025)
congenital myasthenic syndrome
(MONDO_0018940)
Strong
HDAC7
(HGNC:14067)
multiple sclerosis
(MONDO_0005301)
Strong
HDAC7
(HGNC:14067)
systemic lupus erythematosus
(MONDO_0007915)
Limited
CACNG3
(HGNC:1407)
childhood absence epilepsy
(MONDO_0010826)
Strong
ATP1A4
(HGNC:14073)
pelvic organ prolapse
(MONDO_0000082)
Limited
RTN4
(HGNC:14085)
schizophrenia
(MONDO_0005090)
Disputed
PIGQ
(HGNC:14135)
infantile epileptic-dyskinetic encephalopathy
(MONDO_0018226)
Strong
HS3ST6
(HGNC:14178)
hereditary angioedema
(MONDO_0019623)
Moderate
AVIL
(HGNC:14188)
multiple sclerosis
(MONDO_0005301)
Limited
ARHGEF12
(HGNC:14193)
type 2 diabetes mellitus
(MONDO_0005148)
Disputed
ARHGEF12
(HGNC:14193)
OPTN-related open angle glaucoma
(MONDO_0100553)
Strong
JPH1
(HGNC:14201)
congenital myopathy
(MONDO_0019952)
Strong
DERL3
(HGNC:14236)
coronary artery disorder
(MONDO_0005010)
Moderate
MED15
(HGNC:14248)
autism spectrum disorder
(MONDO_0005258)
Limited
RAB23
(HGNC:14263)
Carpenter syndrome
(MONDO_0019012)
Strong
BRPF1
(HGNC:14255)
intellectual developmental disorder with dysmorphic facies and ptosis
(MONDO_0015022)
Strong
GAR1
(HGNC:14264)
dyskeratosis congenita
(MONDO_0015780)
Limited
MRPL4
(HGNC:14276)
allergic rhinitis
(MONDO_0011786)
Moderate
MS4A6E
(HGNC:14285)
Alzheimer disease
(MONDO_0004975)
Strong
NLGN2
(HGNC:14290)
schizophrenia
(MONDO_0005090)
Strong
NLGN2
(HGNC:14290)
autism
(MONDO_0005260)
Limited
GLMN
(HGNC:14373)
glomuvenous malformation
(MONDO_0007672)
Strong
BAALC
(HGNC:14333)
acute myeloid leukemia
(MONDO_0018874)
Strong
ACP4
(HGNC:14376)
amelogenesis imperfecta
(MONDO_0019507)
Strong
WDR13
(HGNC:14352)
X-linked intellectual disability
(MONDO_0100284)
Moderate
OPN4
(HGNC:14449)
circadian rhythm sleep disorder, delayed sleep phase type
(MONDO_0024377)
Limited
ELOVL1
(HGNC:14418)
cerebral palsy
(MONDO_0006497)
Strong
ELOVL1
(HGNC:14418)
progressive supranuclear palsy
(MONDO_0019037)
Strong
KCNK16
(HGNC:14464)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
CALM3
(HGNC:1449)
long QT syndrome
(MONDO_0002442)
Strong
MRPS23
(HGNC:14509)
mitochondrial disease
(MONDO_0044970)
Strong
RASGRP3
(HGNC:14545)
oral cavity cancer
(MONDO_0005515)
Moderate
RASGRP3
(HGNC:14545)
systemic lupus erythematosus
(MONDO_0007915)
Strong
CLEC4E
(HGNC:14555)
pulmonary tuberculosis
(MONDO_0006052)
Limited
KIF13A
(HGNC:14566)
Fuchs' endothelial dystrophy
(MONDO_0005321)
Limited
KIF13A
(HGNC:14566)
progressive supranuclear palsy
(MONDO_0019037)
Moderate
VPS16
(HGNC:14584)
dystonic disorder
(MONDO_0003441)
Strong
NET1
(HGNC:14592)
attention deficit-hyperactivity disorder
(MONDO_0007743)
Limited
TINAG
(HGNC:14599)
dermatophytosis
(MONDO_0004678)
Strong
TINAG
(HGNC:14599)
pectus excavatum
(MONDO_0008213)
Limited
MRPS7
(HGNC:14499)
Perrault syndrome
(MONDO_0017312)
Strong
DSCAML1
(HGNC:14656)
pituitary stalk interruption syndrome
(MONDO_0019828)
Limited
SPATA2
(HGNC:14681)
psoriasis
(MONDO_0005083)
Strong
CDCA5
(HGNC:14626)
Cornelia de Lange syndrome
(MONDO_0016033)
Limited
CAMP
(HGNC:1472)
psoriasis
(MONDO_0005083)
Limited
CAPN11
(HGNC:1478)
benign essential blepharospasm
(MONDO_0011728)
Limited
DCD
(HGNC:14669)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
CAPN5
(HGNC:1482)
CAPN5-related vitreoretinopathy
(MONDO_0100450)
Strong
PPP1R14A
(HGNC:14871)
prostate cancer
(MONDO_0008315)
Strong
COG5
(HGNC:14857)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
TAS2R7
(HGNC:14913)
colorectal cancer
(MONDO_0005575)
Limited
GTPBP3
(HGNC:14880)
combined oxidative phosphorylation defect type 23
(MONDO_0014525)
Strong
GPR37L1
(HGNC:14923)
epilepsy
(MONDO_0005027)
Strong
GPR37L1
(HGNC:14923)
migraine disorder
(MONDO_0005277)
Strong
TAS2R13
(HGNC:14919)
type 2 diabetes mellitus
(MONDO_0005148)
Moderate
TSSK1B
(HGNC:14968)
male infertility
(MONDO_0005372)
Strong
PIGS
(HGNC:14937)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
OR13G1
(HGNC:14999)
coronary artery disorder
(MONDO_0005010)
Disputed
OR13G1
(HGNC:14999)
myocardial infarction
(MONDO_0005068)
Disputed
SNX10
(HGNC:14974)
autosomal recessive osteopetrosis
(MONDO_0019026)
Strong
OR4S2
(HGNC:15183)
obesity disorder
(MONDO_0011122)
Strong
OR9K2
(HGNC:15339)
autism spectrum disorder
(MONDO_0005258)
Limited
OR13C8
(HGNC:15103)
colorectal cancer
(MONDO_0005575)
Limited
CBFA2T3
(HGNC:1537)
acute myeloid leukemia
(MONDO_0018874)
Strong
ZNF331
(HGNC:15489)
breast cancer
(MONDO_0007254)
Strong
XYLT2
(HGNC:15517)
spondylo-ocular syndrome
(MONDO_0011604)
Strong
LBX2
(HGNC:15525)
atrial septal defect
(MONDO_0006664)
Strong
NLGN4Y
(HGNC:15529)
autism
(MONDO_0005260)
Limited
LBX2
(HGNC:15525)
atrial septal defect, ostium secundum type
(MONDO_0020434)
Strong
FAM167A
(HGNC:15549)
systemic lupus erythematosus
(MONDO_0007915)
Strong
CBX2
(HGNC:1552)
schizophrenia
(MONDO_0005090)
Limited
CBX4
(HGNC:1554)
hepatocellular carcinoma
(MONDO_0007256)
Moderate
EPPK1
(HGNC:15577)
childhood acute lymphoblastic leukemia
(MONDO_0000870)
Limited
CBX7
(HGNC:1557)
plasma cell myeloma
(MONDO_0009693)
Strong
SYTL2
(HGNC:15585)
colorectal cancer
(MONDO_0005575)
Strong
SLC12A8
(HGNC:15595)
psoriasis
(MONDO_0005083)
Strong
B3GNT2
(HGNC:15629)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Strong
RASSF9
(HGNC:15739)
familial colorectal cancer type X
(MONDO_0018604)
Disputed
KIRREL1
(HGNC:15734)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Strong
MYL9
(HGNC:15754)
visceral myopathy 1
(MONDO_0020754)
Limited
BPIFA1
(HGNC:15749)
nasopharyngeal carcinoma
(MONDO_0015459)
Strong
BPIFA1
(HGNC:15749)
lung cancer
(MONDO_0008903)
Limited
MYL9
(HGNC:15754)
megacystis-microcolon-intestinal hypoperistalsis syndrome
(MONDO_0025986)
Strong
MOCS3
(HGNC:15765)
sulfite oxidase deficiency due to molybdenum cofactor deficiency
(MONDO_0020480)
Strong
GZF1
(HGNC:15808)
Larsen syndrome
(MONDO_0007875)
Strong
TP53TG5
(HGNC:15856)
intellectual disability
(MONDO_0001071)
Limited
CCNF
(HGNC:1591)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
IFT52
(HGNC:15901)
cranioectodermal dysplasia
(MONDO_0009032)
Strong
IFT52
(HGNC:15901)
ciliopathy
(MONDO_0005308)
Strong
SLC2A4RG
(HGNC:15930)
multiple sclerosis
(MONDO_0005301)
Strong
NDUFAF5
(HGNC:15899)
Leigh syndrome
(MONDO_0009723)
Strong
WFDC2
(HGNC:15939)
ovarian carcinoma
(MONDO_0005140)
Limited
ZHX3
(HGNC:15935)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
IFT52
(HGNC:15901)
Jeune syndrome
(MONDO_0018770)
Strong
L3MBTL1
(HGNC:15905)
Shwachman-Diamond syndrome
(MONDO_0009833)
Limited
TOE1
(HGNC:15954)
pontocerebellar hypoplasia type 7
(MONDO_0013993)
Strong
DAZ2
(HGNC:15964)
male infertility
(MONDO_0005372)
Strong
SEZ6
(HGNC:15955)
childhood-onset schizophrenia
(MONDO_0957430)
Limited
SLC2A13
(HGNC:15956)
Parkinson disease
(MONDO_0005180)
Strong
TRIM2
(HGNC:15974)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
MPLKIP
(HGNC:16002)
trichothiodystrophy
(MONDO_0018053)
Strong
MOB1A
(HGNC:16015)
Alzheimer disease
(MONDO_0004975)
Strong
TRIM63
(HGNC:16007)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
COLEC12
(HGNC:16016)
diabetic retinopathy
(MONDO_0005266)
Moderate
MED12L
(HGNC:16050)
uterine corpus leiomyoma
(MONDO_0007886)
Limited
PAK4
(HGNC:16059)
gastric cancer
(MONDO_0001056)
Moderate
ACER3
(HGNC:16066)
leukodystrophy
(MONDO_0019046)
Strong
MLLT10
(HGNC:16063)
acute myeloid leukemia
(MONDO_0018874)
Strong
LIMS2
(HGNC:16084)
limb-girdle muscular dystrophy
(MONDO_0016971)
Moderate
STMN4
(HGNC:16078)
autism spectrum disorder
(MONDO_0005258)
Limited
SFXN4
(HGNC:16088)
macrocytic anemia
(MONDO_0002281)
Limited
PGRMC1
(HGNC:16090)
premature menopause
(MONDO_0001119)
Limited
SFXN4
(HGNC:16088)
mitochondrial disease
(MONDO_0044970)
Moderate
BPIFB1
(HGNC:16108)
lung adenocarcinoma
(MONDO_0005061)
Limited
TBC1D20
(HGNC:16133)
Martsolf syndrome
(MONDO_0023910)
Strong
FITM2
(HGNC:16135)
deafness dystonia syndrome
(MONDO_0010578)
Strong
CABLES2
(HGNC:16143)
colorectal cancer
(MONDO_0005575)
Moderate
CRLS1
(HGNC:16148)
Leigh syndrome
(MONDO_0009723)
Disputed
SLC17A9
(HGNC:16192)
porokeratosis
(MONDO_0006602)
Limited
TRPC4AP
(HGNC:16181)
Alzheimer disease
(MONDO_0004975)
Strong
DNAJC5
(HGNC:16235)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Strong
XCR1
(HGNC:1625)
COVID-19
(MONDO_0100096)
Strong
TGM6
(HGNC:16255)
spinocerebellar ataxia type 35
(MONDO_0013485)
Disputed
RAD21L1
(HGNC:16271)
azoospermia
(MONDO_0100459)
Strong
SYAP1
(HGNC:16273)
autism spectrum disorder
(MONDO_0005258)
Strong
GALNT17
(HGNC:16347)
Parkinson disease
(MONDO_0005180)
Limited
NSUN5
(HGNC:16385)
Williams syndrome
(MONDO_0008678)
Limited
GALNT17
(HGNC:16347)
Williams syndrome
(MONDO_0008678)
Limited
CARD6
(HGNC:16394)
primary myelofibrosis
(MONDO_0009692)
Limited
BUD23
(HGNC:16405)
Williams syndrome
(MONDO_0008678)
Limited
CGB5
(HGNC:16452)
habitual spontaneous abortion
(MONDO_0006774)
Strong
DNAJC30
(HGNC:16410)
Leber hereditary optic neuropathy
(MONDO_0010788)
Strong
CGB8
(HGNC:16453)
habitual spontaneous abortion
(MONDO_0006774)
Strong
ACAP1
(HGNC:16467)
breast cancer
(MONDO_0007254)
Strong
ADAP1
(HGNC:16486)
dementia
(MONDO_0001627)
Strong
ADAP1
(HGNC:16486)
Crohn disease
(MONDO_0005011)
Strong
ADAP1
(HGNC:16486)
cerebrovascular disorder
(MONDO_0011057)
Strong
ATG4A
(HGNC:16489)
Crohn disease
(MONDO_0005011)
Disputed
LCE3C
(HGNC:16612)
psoriasis
(MONDO_0005083)
Strong
PDLIM4
(HGNC:16501)
prostate cancer
(MONDO_0008315)
Strong
LCE3D
(HGNC:16615)
psoriasis
(MONDO_0005083)
Strong
MRPS34
(HGNC:16618)
Leigh syndrome
(MONDO_0009723)
Strong
SLMAP
(HGNC:16643)
Brugada syndrome
(MONDO_0015263)
Strong
MRPL44
(HGNC:16650)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
WDR17
(HGNC:16661)
colorectal cancer
(MONDO_0005575)
Limited
ANP32B
(HGNC:16677)
common variable immunodeficiency
(MONDO_0015517)
Limited
EIF4ENIF1
(HGNC:16687)
premature menopause
(MONDO_0001119)
Strong
SLC17A7
(HGNC:16704)
schizophrenia
(MONDO_0005090)
Moderate
DHX34
(HGNC:16719)
myelodysplastic syndrome
(MONDO_0018881)
Strong
CIZ1
(HGNC:16744)
benign essential blepharospasm
(MONDO_0011728)
Limited
CD3D
(HGNC:1673)
severe combined immunodeficiency
(MONDO_0015974)
Strong
CIZ1
(HGNC:16744)
dystonic disorder
(MONDO_0003441)
Moderate
CD3E
(HGNC:1674)
severe combined immunodeficiency
(MONDO_0015974)
Strong
SMG7
(HGNC:16792)
prostate cancer
(MONDO_0008315)
Moderate
WWP2
(HGNC:16804)
osteoarthritis, knee
(MONDO_0005416)
Moderate
ACTR1A
(HGNC:167)
malignant pleural mesothelioma
(MONDO_0005112)
Limited
PHOSPHO1
(HGNC:16815)
obesity disorder
(MONDO_0011122)
Limited
DACH2
(HGNC:16814)
premature menopause
(MONDO_0001119)
Limited
ESS2
(HGNC:16817)
DiGeorge syndrome
(MONDO_0008564)
Limited
ESS2
(HGNC:16817)
velocardiofacial syndrome
(MONDO_0008644)
Limited
NOP14
(HGNC:16821)
pancreatic ductal adenocarcinoma
(MONDO_0005184)
Moderate
CD47
(HGNC:1682)
colorectal cancer
(MONDO_0005575)
Strong
HCAR3
(HGNC:16824)
schizophrenia
(MONDO_0005090)
Strong
SH2D3A
(HGNC:16885)
COVID-19
(MONDO_0100096)
Strong
CD96
(HGNC:16892)
C syndrome
(MONDO_0008893)
Limited
CD96
(HGNC:16892)
Bohring-Opitz syndrome
(MONDO_0011510)
Limited
CD59
(HGNC:1689)
paroxysmal nocturnal hemoglobinuria
(MONDO_0100244)
Strong
SPEG
(HGNC:16901)
centronuclear myopathy
(MONDO_0018947)
Strong
BCKDK
(HGNC:16902)
maple syrup urine disease
(MONDO_0009563)
Strong
EMG1
(HGNC:16912)
Bowen-Conradi syndrome
(MONDO_0008879)
Strong
STAMBP
(HGNC:16950)
microcephaly-capillary malformation syndrome
(MONDO_0013659)
Strong
SEC61B
(HGNC:16993)
autosomal dominant polycystic liver disease
(MONDO_0000447)
Strong
SEC61B
(HGNC:16993)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Limited
CEP43
(HGNC:17012)
primary myelofibrosis
(MONDO_0009692)
Limited
HSPH1
(HGNC:16969)
colorectal cancer
(MONDO_0005575)
Strong
HPS5
(HGNC:17022)
Hermansky-Pudlak syndrome
(MONDO_0019312)
Strong
COL21A1
(HGNC:17025)
hypertensive disorder
(MONDO_0005044)
Strong
PUF60
(HGNC:17042)
8q24.3 microdeletion syndrome
(MONDO_0014263)
Strong
SARM1
(HGNC:17074)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
SWAP70
(HGNC:17070)
rheumatoid arthritis
(MONDO_0008383)
Strong
GGA3
(HGNC:17079)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
TFIP11
(HGNC:17165)
dental caries
(MONDO_0005276)
Limited
IL26
(HGNC:17119)
multiple sclerosis
(MONDO_0005301)
Limited
ADAMTS17
(HGNC:17109)
Weill-Marchesani syndrome
(MONDO_0018096)
Strong
RAB3GAP2
(HGNC:17168)
Warburg micro syndrome
(MONDO_0016649)
Strong
ASB10
(HGNC:17185)
glaucoma
(MONDO_0005041)
Disputed
ASB10
(HGNC:17185)
open-angle glaucoma
(MONDO_0005338)
Disputed
RAB3GAP2
(HGNC:17168)
Martsolf syndrome
(MONDO_0023910)
Strong
OLFM1
(HGNC:17187)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
NDUFA13
(HGNC:17194)
Leigh syndrome
(MONDO_0009723)
Moderate
HELB
(HGNC:17196)
ovarian carcinoma
(MONDO_0005140)
Strong
STK36
(HGNC:17209)
Temple-Baraitser syndrome
(MONDO_0012735)
Limited
ELMO2
(HGNC:17233)
Ramon syndrome
(MONDO_0009954)
Limited
ABI3BP
(HGNC:17265)
colorectal cancer
(MONDO_0005575)
Limited
DHX38
(HGNC:17211)
retinitis pigmentosa
(MONDO_0019200)
Strong
STK36
(HGNC:17209)
Zimmermann-Laband syndrome
(MONDO_0000200)
Limited
PASK
(HGNC:17270)
2q37 microdeletion syndrome
(MONDO_0010886)
Limited
IP6K2
(HGNC:17313)
Parkinson disease
(MONDO_0005180)
Limited
IL27RA
(HGNC:17290)
asthma
(MONDO_0004979)
Limited
RRAS2
(HGNC:17271)
Noonan syndrome
(MONDO_0018997)
Strong
RXFP2
(HGNC:17318)
cryptorchidism
(MONDO_0009047)
Strong
AASS
(HGNC:17366)
hyperlysinemia
(MONDO_0009388)
Strong
NAGPA
(HGNC:17378)
stutter disorder
(MONDO_0000723)
Strong
APIP
(HGNC:17581)
cystic fibrosis
(MONDO_0009061)
Strong
FHL5
(HGNC:17371)
migraine disorder
(MONDO_0005277)
Strong
CHIA
(HGNC:17432)
asthma
(MONDO_0004979)
Strong
GMNN
(HGNC:17493)
Meier-Gorlin syndrome
(MONDO_0016817)
Limited
TBRG4
(HGNC:17443)
plasma cell myeloma
(MONDO_0009693)
Strong
RANGRF
(HGNC:17679)
Brugada syndrome
(MONDO_0015263)
Limited
ACBD7
(HGNC:17715)
anorexia nervosa
(MONDO_0005351)
Limited
STK38L
(HGNC:17848)
intellectual disability
(MONDO_0001071)
Strong
STK38L
(HGNC:17848)
Kallmann syndrome
(MONDO_0018800)
Limited
BBC3
(HGNC:17868)
breast cancer
(MONDO_0007254)
Limited
ACY1
(HGNC:177)
aminoacylase 1 deficiency
(MONDO_0012368)
Strong
FHOD1
(HGNC:17905)
congenital hypotrichosis with juvenile macular dystrophy
(MONDO_0011107)
Limited
SLC45A1
(HGNC:17939)
intellectual disability
(MONDO_0001071)
Strong
PSMC3IP
(HGNC:17928)
premature menopause
(MONDO_0001119)
Moderate
RDH11
(HGNC:17964)
retinitis pigmentosa
(MONDO_0019200)
Moderate
ROBO4
(HGNC:17985)
aortic valve disease 3
(MONDO_0032783)
Strong
B3GALT6
(HGNC:17978)
spondyloepimetaphyseal dysplasia with joint laxity, type 1, with or without fractures
(MONDO_0010075)
Strong
NUDT11
(HGNC:18011)
prostate cancer
(MONDO_0008315)
Strong
NUP133
(HGNC:18016)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Strong
NUP133
(HGNC:18016)
Galloway-Mowat syndrome
(MONDO_0009627)
Strong
NUP160
(HGNC:18017)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Strong
BMP2K
(HGNC:18041)
developmental dysplasia of the hip
(MONDO_0000158)
Strong
OSGEP
(HGNC:18028)
Galloway-Mowat syndrome
(MONDO_0009627)
Strong
ZFAND3
(HGNC:18019)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
CDX1
(HGNC:1805)
mesenchymal chondrosarcoma
(MONDO_0006853)
Limited
SLC38A3
(HGNC:18044)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
AHSP
(HGNC:18075)
beta thalassemia
(MONDO_0019402)
Limited
TMEM199
(HGNC:18085)
TMEM199-CDG
(MONDO_0014790)
Strong
STYXL1
(HGNC:18165)
epilepsy
(MONDO_0005027)
Disputed
RNF115
(HGNC:18154)
breast cancer
(MONDO_0007254)
Strong
TMEM199
(HGNC:18085)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
TRPV3
(HGNC:18084)
Olmsted syndrome
(MONDO_0031421)
Strong
CD244
(HGNC:18171)
rheumatoid arthritis
(MONDO_0008383)
Limited
COQ3
(HGNC:18175)
multiple sclerosis
(MONDO_0005301)
Limited
TPCN1
(HGNC:18182)
Alzheimer disease
(MONDO_0004975)
Strong
TRERF1
(HGNC:18273)
intellectual disability
(MONDO_0001071)
Moderate
TMLHE
(HGNC:18308)
autism spectrum disorder
(MONDO_0005258)
Strong
TMLHE
(HGNC:18308)
autism
(MONDO_0005260)
Moderate
PRIMA1
(HGNC:18319)
atherosclerosis
(MONDO_0005311)
Strong
DHRS2
(HGNC:18349)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
RAD18
(HGNC:18278)
colorectal cancer
(MONDO_0005575)
Strong
CENPM
(HGNC:18352)
schizophrenia
(MONDO_0005090)
Strong
CEACAM8
(HGNC:1820)
essential thrombocythemia
(MONDO_0005029)
Limited
ACER1
(HGNC:18356)
Farber lipogranulomatosis
(MONDO_0009218)
Strong
CLYBL
(HGNC:18355)
vitamin B12 deficiency
(MONDO_0020696)
Strong
PADI1
(HGNC:18367)
periodontitis
(MONDO_0005076)
Limited
RAX2
(HGNC:18286)
inherited retinal dystrophy
(MONDO_0019118)
Strong
AGMAT
(HGNC:18407)
3-methylglutaconic aciduria type 1
(MONDO_0009610)
Strong
IFNL2
(HGNC:18364)
hepatitis C virus infection
(MONDO_0005231)
Limited
SMARCAD1
(HGNC:18398)
absence of fingerprints-congenital milia syndrome
(MONDO_0007507)
Strong
HIP1R
(HGNC:18415)
Parkinson disease
(MONDO_0005180)
Strong
AGO3
(HGNC:18421)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
GRID2IP
(HGNC:18464)
autism
(MONDO_0005260)
Limited
CECR2
(HGNC:1840)
cat-eye syndrome
(MONDO_0007276)
Limited
TFB2M
(HGNC:18559)
autism spectrum disorder
(MONDO_0005258)
Limited
PIWIL3
(HGNC:18443)
premature menopause
(MONDO_0001119)
Strong
SPART
(HGNC:18514)
Troyer syndrome
(MONDO_0010156)
Strong
FCRL1
(HGNC:18509)
EAST syndrome
(MONDO_0013005)
Limited
SPART
(HGNC:18514)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
CYS1
(HGNC:18525)
autosomal recessive polycystic kidney disease
(MONDO_0009889)
Strong
ZDHHC9
(HGNC:18475)
X-linked intellectual disability
(MONDO_0100284)
Strong
CCNO
(HGNC:18576)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
LRRK1
(HGNC:18608)
Parkinson disease
(MONDO_0005180)
Limited
NEK9
(HGNC:18591)
nevus comedonicus syndrome
(MONDO_0014873)
Strong
LRRK1
(HGNC:18608)
osteosclerotic metaphyseal dysplasia
(MONDO_0014080)
Strong
MSI2
(HGNC:18585)
schizophrenia
(MONDO_0005090)
Strong
FKBP14
(HGNC:18625)
Ehlers-Danlos syndrome
(MONDO_0020066)
Strong
BLOC1S5
(HGNC:18561)
Hermansky-Pudlak syndrome
(MONDO_0019312)
Strong
KMT2E
(HGNC:18541)
O'Donnell-Luria-Rodan syndrome
(MONDO_0032793)
Strong
CER1
(HGNC:1862)
osteoporosis
(MONDO_0005298)
Strong
SUGP2
(HGNC:18641)
hereditary hemochromatosis
(MONDO_0006507)
Strong
ZBTB7B
(HGNC:18668)
prostate cancer
(MONDO_0008315)
Strong
PALS1
(HGNC:18669)
COVID-19
(MONDO_0100096)
Limited
EIF4A3
(HGNC:18683)
Richieri Costa-Pereira syndrome
(MONDO_0009998)
Strong
DDX4
(HGNC:18700)
neuroblastoma
(MONDO_0005072)
Limited
NFXL1
(HGNC:18726)
specific language impairment
(MONDO_0000724)
Moderate
SLURP1
(HGNC:18746)
mal de Meleda
(MONDO_0009552)
Strong
CRB2
(HGNC:18688)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Strong
CFL2
(HGNC:1875)
myofibrillar myopathy
(MONDO_0018943)
Limited
RIN2
(HGNC:18750)
RIN2 syndrome
(MONDO_0013115)
Strong
KLHL10
(HGNC:18829)
male infertility
(MONDO_0005372)
Moderate
CREB3L4
(HGNC:18854)
prostate cancer
(MONDO_0008315)
Strong
CREB3L1
(HGNC:18856)
osteogenesis imperfecta
(MONDO_0019019)
Strong
KCNRG
(HGNC:18893)
B-cell chronic lymphocytic leukemia
(MONDO_0004948)
Limited
PIGM
(HGNC:18858)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
TAS2R31
(HGNC:19113)
autism spectrum disorder
(MONDO_0005258)
Limited
SLCO5A1
(HGNC:19046)
mesomelia-synostoses syndrome
(MONDO_0010881)
Strong
S100A14
(HGNC:18901)
esophageal squamous cell carcinoma
(MONDO_0005580)
Strong
CORIN
(HGNC:19012)
hypertensive disorder
(MONDO_0005044)
Strong
ADGRF1
(HGNC:18990)
lung cancer
(MONDO_0008903)
Strong
TTBK1
(HGNC:19140)
childhood-onset schizophrenia
(MONDO_0957430)
Limited
CHD1
(HGNC:1915)
prostate cancer
(MONDO_0008315)
Strong
TTBK2
(HGNC:19141)
spinocerebellar ataxia type 11
(MONDO_0011464)
Strong
CMTM7
(HGNC:19178)
Mayer-Rokitansky-Kuster-Hauser syndrome
(MONDO_0017771)
Limited
SASH1
(HGNC:19182)
dyschromatosis universalis hereditaria
(MONDO_0000736)
Strong
WSB1
(HGNC:19221)
COVID-19
(MONDO_0100096)
Moderate
UBE2Q2
(HGNC:19248)
chronic kidney disease
(MONDO_0005300)
Strong
SYT9
(HGNC:19265)
maturity-onset diabetes of the young
(MONDO_0018911)
Limited
PPP6R2
(HGNC:19253)
Parkinson disease
(MONDO_0005180)
Strong
SLC30A7
(HGNC:19306)
Joubert syndrome
(MONDO_0018772)
Limited
DENND5A
(HGNC:19344)
intellectual disability
(MONDO_0001071)
Strong
BET1L
(HGNC:19348)
uterine corpus leiomyoma
(MONDO_0007886)
Strong
CHI3L2
(HGNC:1933)
pancreatic ductal adenocarcinoma
(MONDO_0005184)
Strong
MDGA1
(HGNC:19267)
schizophrenia
(MONDO_0005090)
Moderate
SIN3A
(HGNC:19353)
SIN3A-related intellectual disability syndrome due to a point mutation
(MONDO_0044700)
Strong
PIM3
(HGNC:19310)
Phelan-McDermid syndrome
(MONDO_0011652)
Limited
SIN3B
(HGNC:19354)
esthesioneuroblastoma
(MONDO_0016029)
Limited
TP53I3
(HGNC:19373)
ovarian cancer
(MONDO_0008170)
Moderate
ALG12
(HGNC:19358)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
DPY19L2
(HGNC:19414)
spermatogenic failure 6
(MONDO_0007060)
Strong
ALG12
(HGNC:19358)
ALG12-congenital disorder of glycosylation
(MONDO_0011783)
Strong
CHRM5
(HGNC:1954)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Limited
CHN1
(HGNC:1943)
Duane retraction syndrome
(MONDO_0007473)
Strong
TNNI3K
(HGNC:19661)
dilated cardiomyopathy
(MONDO_0005021)
Strong
GPBAR1
(HGNC:19680)
ulcerative colitis
(MONDO_0005101)
Strong
CHRM5
(HGNC:1954)
cauda equina syndrome with neurogenic bladder
(MONDO_0020767)
Limited
UHMK1
(HGNC:19683)
schizophrenia
(MONDO_0005090)
Strong
GPBAR1
(HGNC:19680)
primary sclerosing cholangitis
(MONDO_0013433)
Strong
RD3
(HGNC:19689)
Leber congenital amaurosis
(MONDO_0018998)
Strong
FGFBP1
(HGNC:19695)
hypertensive disorder
(MONDO_0005044)
Strong
STXBP4
(HGNC:19694)
breast cancer
(MONDO_0007254)
Strong
FNBP4
(HGNC:19752)
microphthalmia with limb anomalies
(MONDO_0008800)
Limited
CIDEA
(HGNC:1976)
obesity disorder
(MONDO_0011122)
Strong
CANT1
(HGNC:19721)
Desbuquois dysplasia
(MONDO_0015426)
Strong
CIDEB
(HGNC:1977)
cirrhosis of liver
(MONDO_0005155)
Strong
CIDEB
(HGNC:1977)
metabolic dysfunction-associated steatotic liver disease
(MONDO_0013209)
Moderate
TSSK4
(HGNC:19825)
male infertility
(MONDO_0005372)
Moderate
UTP4
(HGNC:1983)
hereditary North American Indian childhood cirrhosis
(MONDO_0011497)
Strong
EPB41L4B
(HGNC:19818)
colorectal cancer
(MONDO_0005575)
Limited
TC2N
(HGNC:19859)
von Willebrand disease (hereditary or acquired)
(MONDO_0024574)
Limited
POU2F3
(HGNC:19864)
psoriasis
(MONDO_0005083)
Strong
GBP5
(HGNC:19895)
ovarian cancer
(MONDO_0008170)
Limited
MMRN2
(HGNC:19888)
Parkinson disease
(MONDO_0005180)
Limited
SCARF2
(HGNC:19869)
van den Ende-Gupta syndrome
(MONDO_0010959)
Strong
MYORG
(HGNC:19918)
basal ganglia calcification, idiopathic, 1
(MONDO_0024538)
Strong
PLSCR5
(HGNC:19952)
bipolar disorder
(MONDO_0004985)
Limited
ADAM20
(HGNC:199)
Alzheimer disease
(MONDO_0004975)
Strong
USP36
(HGNC:20062)
premature menopause
(MONDO_0001119)
Moderate
USP46
(HGNC:20075)
essential tremor
(MONDO_0003233)
Limited
ZNF408
(HGNC:20041)
exudative vitreoretinopathy
(MONDO_0019516)
Strong
CHURC1
(HGNC:20099)
autism
(MONDO_0005260)
Limited
FLVCR2
(HGNC:20105)
Fowler syndrome
(MONDO_0009168)
Strong
TEDC1
(HGNC:20127)
autosomal recessive primary microcephaly
(MONDO_0016660)
Moderate
ABHD4
(HGNC:20154)
anorexia nervosa
(MONDO_0005351)
Limited
ASPG
(HGNC:20123)
aspartylglucosaminuria
(MONDO_0008830)
Strong
INTS13
(HGNC:20174)
intellectual disability
(MONDO_0001071)
Moderate
NRDE2
(HGNC:20186)
hepatocellular carcinoma
(MONDO_0007256)
Strong
INTS13
(HGNC:20174)
Kallmann syndrome
(MONDO_0018800)
Strong
DNAAF2
(HGNC:20188)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
CLCA4
(HGNC:2018)
colorectal cancer
(MONDO_0005575)
Strong
VRTN
(HGNC:20223)
Alzheimer disease
(MONDO_0004975)
Strong
KIF26A
(HGNC:20226)
Hirschsprung disease
(MONDO_0018309)
Strong
AJUBA
(HGNC:20250)
esophageal squamous cell carcinoma
(MONDO_0005580)
Strong
SFMBT1
(HGNC:20255)
Poland syndrome
(MONDO_0008262)
Limited
SFMBT1
(HGNC:20255)
colorectal cancer
(MONDO_0005575)
Moderate
LRRC10
(HGNC:20264)
dilated cardiomyopathy
(MONDO_0005021)
Strong
SFMBT1
(HGNC:20255)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
ALG5
(HGNC:20266)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Strong
CHAMP1
(HGNC:20311)
intellectual disability
(MONDO_0001071)
Strong
TGDS
(HGNC:20324)
Catel-Manzke syndrome
(MONDO_0014507)
Strong
UBR7
(HGNC:20344)
Li-Campeau syndrome
(MONDO_0030963)
Strong
LRFN5
(HGNC:20360)
intellectual disability
(MONDO_0001071)
Limited
SMOC1
(HGNC:20318)
microphthalmia with limb anomalies
(MONDO_0008800)
Strong
SPTSSA
(HGNC:20361)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
PLEKHG3
(HGNC:20364)
autism
(MONDO_0005260)
Limited
LRFN5
(HGNC:20360)
autism spectrum disorder
(MONDO_0005258)
Limited
SQOR
(HGNC:20390)
Leigh syndrome
(MONDO_0009723)
Strong
SPG21
(HGNC:20373)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
PILRA
(HGNC:20396)
Alzheimer disease
(MONDO_0004975)
Moderate
SPG21
(HGNC:20373)
mast syndrome
(MONDO_0009568)
Strong
ZIC4
(HGNC:20393)
Dandy-Walker syndrome
(MONDO_0009072)
Limited
MBIP
(HGNC:20427)
thyroid gland papillary carcinoma
(MONDO_0005075)
Moderate
TREML1
(HGNC:20434)
Alzheimer disease
(MONDO_0004975)
Limited
CLDN18
(HGNC:2039)
colorectal cancer
(MONDO_0005575)
Moderate
RNF144A
(HGNC:20457)
schizophrenia
(MONDO_0005090)
Strong
CLDN5
(HGNC:2047)
schizophrenia
(MONDO_0005090)
Moderate
NME7
(HGNC:20461)
venous thromboembolism
(MONDO_0005399)
Strong
LSM7
(HGNC:20470)
leukodystrophy
(MONDO_0019046)
Strong
CATSPERB
(HGNC:20500)
colorectal cancer
(MONDO_0005575)
Limited
LSM1
(HGNC:20472)
neurodevelopmental disorder
(MONDO_0700092)
Strong
TAS2R60
(HGNC:20639)
Alzheimer disease
(MONDO_0004975)
Moderate
RAPGEF6
(HGNC:20655)
schizophrenia
(MONDO_0005090)
Strong
CLEC5A
(HGNC:2054)
Crohn disease
(MONDO_0005011)
Limited
TSPAN1
(HGNC:20657)
prostate cancer
(MONDO_0008315)
Limited
RAPGEF6
(HGNC:20655)
malignant pleural mesothelioma
(MONDO_0005112)
Moderate
SCN3B
(HGNC:20665)
Brugada syndrome
(MONDO_0015263)
Strong
TWIST2
(HGNC:20670)
Barber-Say syndrome
(MONDO_0008853)
Strong
TWIST2
(HGNC:20670)
focal facial dermal dysplasia type III
(MONDO_0009203)
Strong
ZBED3
(HGNC:20711)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
ELP3
(HGNC:20696)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
SCFD1
(HGNC:20726)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
GNB4
(HGNC:20731)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
ARMC9
(HGNC:20730)
Joubert syndrome
(MONDO_0018772)
Strong
CLPP
(HGNC:2084)
Perrault syndrome
(MONDO_0017312)
Strong
ANKFY1
(HGNC:20763)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Moderate
FNBP1L
(HGNC:20851)
Alzheimer disease
(MONDO_0004975)
Moderate
LRIG2
(HGNC:20889)
Ochoa syndrome
(MONDO_0000463)
Strong
ADAM30
(HGNC:208)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
DZIP1
(HGNC:20908)
mitral valve prolapse
(MONDO_0004910)
Strong
BLOC1S3
(HGNC:20914)
Hermansky-Pudlak syndrome
(MONDO_0019312)
Strong
PHACTR2
(HGNC:20956)
lung cancer
(MONDO_0008903)
Strong
ADGRL3
(HGNC:20974)
attention deficit-hyperactivity disorder
(MONDO_0007743)
Strong
CMA1
(HGNC:2097)
atopic eczema
(MONDO_0004980)
Moderate
ZMYND15
(HGNC:20997)
azoospermia
(MONDO_0100459)
Strong
CPO
(HGNC:21011)
hereditary coproporphyria
(MONDO_0007369)
Strong
ARHGAP15
(HGNC:21030)
diverticulitis
(MONDO_0004235)
Strong
ARHGAP18
(HGNC:21035)
schizophrenia
(MONDO_0005090)
Strong
RSPH3
(HGNC:21054)
male infertility
(MONDO_0005372)
Strong
NDUFAF4
(HGNC:21034)
Leigh syndrome
(MONDO_0009723)
Strong
MOXD1
(HGNC:21063)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Limited
TBC1D7
(HGNC:21066)
intellectual disability
(MONDO_0001071)
Strong
RSPH3
(HGNC:21054)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
NCOA7
(HGNC:21081)
breast cancer
(MONDO_0007254)
Limited
SFT2D1
(HGNC:21102)
exocrine pancreatic carcinoma
(MONDO_0005192)
Moderate
TBC1D7
(HGNC:21066)
megalencephaly
(MONDO_0016608)
Strong
FAM120B
(HGNC:21109)
type 1 diabetes mellitus
(MONDO_0005147)
Refuted
CEP162
(HGNC:21107)
diabetic retinopathy
(MONDO_0005266)
Moderate
RNF125
(HGNC:21150)
Tenorio syndrome
(MONDO_0014553)
Strong
ARFGEF3
(HGNC:21213)
intellectual disability
(MONDO_0001071)
Limited
GTF2H5
(HGNC:21157)
trichothiodystrophy
(MONDO_0018053)
Strong
RHOT2
(HGNC:21169)
Parkinson disease
(MONDO_0005180)
Disputed
DNPH1
(HGNC:21218)
breast cancer
(MONDO_0007254)
Strong
ADTRP
(HGNC:21214)
coronary artery disorder
(MONDO_0005010)
Strong
CILK1
(HGNC:21219)
endocrine-cerebro-osteodysplasia syndrome
(MONDO_0012980)
Strong
CILK1
(HGNC:21219)
juvenile myoclonic epilepsy
(MONDO_0009696)
Strong
HMCN2
(HGNC:21293)
periodontitis
(MONDO_0005076)
Strong
ADPRHL1
(HGNC:21303)
prostate cancer
(MONDO_0008315)
Strong
EPS8L3
(HGNC:21297)
Marie Unna hereditary hypotrichosis
(MONDO_0018631)
Disputed
SKOR1
(HGNC:21326)
restless legs syndrome
(MONDO_0005391)
Strong
RNF146
(HGNC:21336)
breast cancer
(MONDO_0007254)
Strong
SLAMF6
(HGNC:21392)
Graves disease
(MONDO_0005364)
Strong
OGFRL1
(HGNC:21378)
cherubism
(MONDO_0007315)
Limited
ECHDC1
(HGNC:21489)
breast cancer
(MONDO_0007254)
Limited
SLAMF6
(HGNC:21392)
rheumatoid arthritis
(MONDO_0008383)
Strong
CNGA2
(HGNC:2149)
isolated congenital anosmia
(MONDO_0007137)
Strong
CNGA1
(HGNC:2148)
retinitis pigmentosa
(MONDO_0019200)
Strong
TSPYL4
(HGNC:21559)
Dravet syndrome
(MONDO_0100135)
Limited
THEMIS
(HGNC:21569)
systemic lupus erythematosus
(MONDO_0007915)
Strong
THEMIS
(HGNC:21569)
type 1 diabetes mellitus
(MONDO_0005147)
Strong
NKAPL
(HGNC:21584)
schizophrenia
(MONDO_0005090)
Strong
AIG1
(HGNC:21607)
osteoarthritis
(MONDO_0005178)
Limited
THEMIS
(HGNC:21569)
rheumatoid arthritis
(MONDO_0008383)
Strong
LUC7L2
(HGNC:21608)
myelodysplastic syndrome
(MONDO_0018881)
Strong
LNPK
(HGNC:21610)
neurodevelopmental disorder with epilepsy and hypoplasia of the corpus callosum
(MONDO_0060761)
Limited
LNPK
(HGNC:21610)
hepatic veno-occlusive disease
(MONDO_0019514)
Limited
CEP85L
(HGNC:21638)
lissencephaly spectrum disorders
(MONDO_0018838)
Strong
ZNF460
(HGNC:21628)
schizophrenia
(MONDO_0005090)
Moderate
OSTM1
(HGNC:21652)
autosomal recessive osteopetrosis
(MONDO_0019026)
Strong
ZNF462
(HGNC:21684)
metopic ridging-ptosis-facial dysmorphism syndrome
(MONDO_0044715)
Strong
IFNK
(HGNC:21714)
colorectal cancer
(MONDO_0005575)
Strong
LHX6
(HGNC:21735)
Tourette syndrome
(MONDO_0007661)
Moderate
RNF216
(HGNC:21698)
cerebellar ataxia-hypogonadism syndrome
(MONDO_0008935)
Strong
RBM28
(HGNC:21863)
ANE syndrome
(MONDO_0012794)
Strong
FBXL18
(HGNC:21874)
autism
(MONDO_0005260)
Limited
IQUB
(HGNC:21995)
bipolar disorder
(MONDO_0004985)
Limited
SCRN1
(HGNC:22192)
gastric cancer
(MONDO_0001056)
Strong
AGK
(HGNC:21869)
Sengers syndrome
(MONDO_0008922)
Strong
AP5Z1
(HGNC:22197)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
KCTD13
(HGNC:22234)
hypospadias
(MONDO_0005345)
Strong
VMA21
(HGNC:22082)
X-linked myopathy with excessive autophagy
(MONDO_0010684)
Strong
C7orf50
(HGNC:22421)
age-related macular degeneration
(MONDO_0005150)
Limited
COPB2
(HGNC:2232)
blepharophimosis, ptosis, and epicanthus inversus syndrome
(MONDO_0007201)
Limited
COX17
(HGNC:2264)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Limited
COPA
(HGNC:2230)
autoimmune interstitial lung disease-arthritis syndrome
(MONDO_0014629)
Strong
COX6A1
(HGNC:2277)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Moderate
FEZF1
(HGNC:22788)
Kallmann syndrome
(MONDO_0018800)
Strong
COX6A2
(HGNC:2279)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Strong
COX6B1
(HGNC:2280)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Strong
SLC25A2
(HGNC:22921)
gastric cancer
(MONDO_0001056)
Limited
GPR155
(HGNC:22951)
lung cancer
(MONDO_0008903)
Moderate
DEPTOR
(HGNC:22953)
lung cancer
(MONDO_0008903)
Limited
PEX26
(HGNC:22965)
peroxisome biogenesis disorder
(MONDO_0019234)
Strong
TMC4
(HGNC:22998)
metabolic dysfunction-associated steatotic liver disease
(MONDO_0013209)
Disputed
CPB1
(HGNC:2299)
pancreatic ductal adenocarcinoma
(MONDO_0005184)
Strong
ARMC2
(HGNC:23045)
male infertility
(MONDO_0005372)
Strong
TM7SF3
(HGNC:23049)
intellectual disability
(MONDO_0001071)
Limited
TM7SF3
(HGNC:23049)
Kallmann syndrome
(MONDO_0018800)
Limited
ALG3
(HGNC:23056)
ALG3-congenital disorder of glycosylation
(MONDO_0010998)
Strong
BRK1
(HGNC:23057)
von Hippel-Lindau disease
(MONDO_0008667)
Strong
ALG3
(HGNC:23056)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
TRAPPC6B
(HGNC:23066)
intellectual disability
(MONDO_0001071)
Strong
TRAPPC2
(HGNC:23068)
spondyloepiphyseal dysplasia tarda, X-linked
(MONDO_0010737)
Definitive
ARHGAP33
(HGNC:23085)
intellectual disability
(MONDO_0001071)
Strong
SLC29A4
(HGNC:23097)
type 2 diabetes mellitus
(MONDO_0005148)
Moderate
RNF150
(HGNC:23138)
chronic obstructive pulmonary disease
(MONDO_0005002)
Limited
TRMT5
(HGNC:23141)
combined oxidative phosphorylation defect type 26
(MONDO_0014684)
Limited
TRMT5
(HGNC:23141)
congestive splenomegaly
(MONDO_0037251)
Limited
U2AF2
(HGNC:23156)
neurodevelopmental disorder
(MONDO_0700092)
Strong
CLINT1
(HGNC:23186)
schizophrenia
(MONDO_0005090)
Disputed
FERMT3
(HGNC:23151)
leukocyte adhesion deficiency 3
(MONDO_0013016)
Strong
CPNE6
(HGNC:2319)
intellectual disability
(MONDO_0001071)
Limited
GKN1
(HGNC:23217)
lung cancer
(MONDO_0008903)
Limited
TSPAN15
(HGNC:23298)
venous thromboembolism
(MONDO_0005399)
Strong
CPOX
(HGNC:2321)
hereditary coproporphyria
(MONDO_0007369)
Strong
TSPAN14
(HGNC:23303)
Alzheimer disease
(MONDO_0004975)
Strong
ACBD6
(HGNC:23339)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
CPZ
(HGNC:2333)
neuroblastoma
(MONDO_0005072)
Strong
PIBF1
(HGNC:23352)
Joubert syndrome
(MONDO_0018772)
Strong
DOLK
(HGNC:23406)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
KIFBP
(HGNC:23419)
Goldberg-Shprintzen syndrome
(MONDO_0012280)
Strong
LIPN
(HGNC:23452)
autosomal recessive congenital ichthyosis
(MONDO_0017265)
Limited
CRAT
(HGNC:2342)
Leigh syndrome
(MONDO_0009723)
Strong
CALHM2
(HGNC:23493)
Alzheimer disease
(MONDO_0004975)
Moderate
ECHDC3
(HGNC:23489)
Alzheimer disease
(MONDO_0004975)
Strong
SLITRK4
(HGNC:23502)
age-related macular degeneration
(MONDO_0005150)
Strong
STOX1
(HGNC:23508)
preeclampsia
(MONDO_0005081)
Strong
PYROXD2
(HGNC:23517)
mitochondrial disease
(MONDO_0044970)
Limited
TUBAL3
(HGNC:23534)
intellectual disability
(MONDO_0001071)
Limited
SLCO4C1
(HGNC:23612)
melanoma
(MONDO_0005105)
Limited
GLT6D1
(HGNC:23671)
acute pericementitis
(MONDO_0001028)
Strong
PLGRKT
(HGNC:23633)
polycystic ovary syndrome
(MONDO_0008487)
Moderate
GLT6D1
(HGNC:23671)
periodontitis
(MONDO_0005076)
Limited
MAMDC2
(HGNC:23673)
intellectual disability
(MONDO_0001071)
Limited
ERMP1
(HGNC:23703)
keratoconus
(MONDO_0015486)
Limited
BCL9L
(HGNC:23688)
B-cell chronic lymphocytic leukemia
(MONDO_0004948)
Moderate
ARHGAP21
(HGNC:23725)
autism spectrum disorder
(MONDO_0005258)
Limited
PTF1A
(HGNC:23734)
neonatal diabetes mellitus
(MONDO_0016391)
Strong
CERS5
(HGNC:23749)
hypertensive disorder
(MONDO_0005044)
Strong
PLD4
(HGNC:23792)
systemic sclerosis
(MONDO_0005100)
Strong
PLD4
(HGNC:23792)
primary biliary cholangitis
(MONDO_0005388)
Strong
MOB3B
(HGNC:23825)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
NDUFA12
(HGNC:23987)
Leigh syndrome
(MONDO_0009723)
Strong
NOC3L
(HGNC:24034)
gastric cancer
(MONDO_0001056)
Strong
CREBRF
(HGNC:24050)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
CREBRF
(HGNC:24050)
obesity disorder
(MONDO_0011122)
Strong
TOR1AIP2
(HGNC:24055)
dystonic disorder
(MONDO_0003441)
Limited
TOR1AIP2
(HGNC:24055)
early-onset generalized limb-onset dystonia
(MONDO_0007492)
Moderate
ROPN1L
(HGNC:24060)
breast cancer
(MONDO_0007254)
Limited
ANGPTL7
(HGNC:24078)
glaucoma
(MONDO_0005041)
Strong
ARAP3
(HGNC:24097)
lymphatic malformation
(MONDO_0019313)
Moderate
ATP13A3
(HGNC:24113)
pulmonary arterial hypertension
(MONDO_0015924)
Strong
MGAT5B
(HGNC:24140)
autism spectrum disorder
(MONDO_0005258)
Limited
WWC2
(HGNC:24148)
restless legs syndrome
(MONDO_0005391)
Limited
BMPER
(HGNC:24154)
diaphanospondylodysostosis
(MONDO_0011946)
Strong
CEBPZ
(HGNC:24218)
acute myeloid leukemia
(MONDO_0018874)
Limited
PHF21A
(HGNC:24156)
Potocki-Shaffer syndrome
(MONDO_0011022)
Strong
CD200R1
(HGNC:24235)
atopic eczema
(MONDO_0004980)
Strong
DRC1
(HGNC:24245)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
NMD3
(HGNC:24250)
Parkinson disease
(MONDO_0005180)
Limited
NCAPD2
(HGNC:24305)
Alzheimer disease
(MONDO_0004975)
Limited
CCDC68
(HGNC:24350)
schizophrenia
(MONDO_0005090)
Limited
CSH1
(HGNC:2440)
Cockayne syndrome
(MONDO_0016006)
Strong
DNER
(HGNC:24456)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
CNDP2
(HGNC:24437)
diabetic kidney disease
(MONDO_0005016)
Strong
DCANP1
(HGNC:24459)
major depressive disorder
(MONDO_0002009)
Disputed
CHST14
(HGNC:24464)
Ehlers-Danlos syndrome, musculocontractural type
(MONDO_0011142)
Strong
POC1A
(HGNC:24488)
short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome
(MONDO_0013894)
Strong
ARHGEF26
(HGNC:24490)
coronary artery disorder
(MONDO_0005010)
Strong
NEPRO
(HGNC:24496)
cartilage-hair hypoplasia
(MONDO_0009595)
Moderate
NEPRO
(HGNC:24496)
anauxetic dysplasia
(MONDO_0011773)
Strong
NEPRO
(HGNC:24496)
anauxetic dysplasia 1
(MONDO_0054560)
Moderate
MPC2
(HGNC:24515)
bipolar disorder
(MONDO_0004985)
Moderate
MPC2
(HGNC:24515)
schizophrenia
(MONDO_0005090)
Strong
TMEM98
(HGNC:24529)
nanophthalmia
(MONDO_0005514)
Strong
DCAF13
(HGNC:24535)
neuromuscular disease
(MONDO_0019056)
Strong
GINS2
(HGNC:24575)
Meier-Gorlin syndrome
(MONDO_0016817)
Strong
RPAP1
(HGNC:24567)
breast cancer
(MONDO_0007254)
Limited
CSNK2A2
(HGNC:2459)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
CXXC4
(HGNC:24593)
myelodysplastic syndrome
(MONDO_0018881)
Strong
DNAJC10
(HGNC:24637)
Parkinson disease
(MONDO_0005180)
Moderate
FIGLA
(HGNC:24669)
premature menopause
(MONDO_0001119)
Strong
GPATCH1
(HGNC:24658)
osteoporosis
(MONDO_0005298)
Strong
VWA2
(HGNC:24709)
chronic kidney disease
(MONDO_0005300)
Limited
DCBLD2
(HGNC:24627)
relapsing polychondritis
(MONDO_0019125)
Moderate
FBLP1
(HGNC:24686)
chronic recurrent multifocal osteomyelitis
(MONDO_0009813)
Limited
CIBAR2
(HGNC:24781)
Crohn disease
(MONDO_0005011)
Disputed
PTCD3
(HGNC:24717)
Leigh syndrome
(MONDO_0009723)
Strong
KLRG2
(HGNC:24778)
prostate cancer
(MONDO_0008315)
Strong
LONRF2
(HGNC:24788)
colorectal cancer
(MONDO_0005575)
Limited
GPRASP1
(HGNC:24834)
arteriovenous hemangioma/malformation
(MONDO_0001256)
Strong
VWA2
(HGNC:24709)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Limited
CIBAR2
(HGNC:24781)
ulcerative colitis
(MONDO_0005101)
Limited
FN3K
(HGNC:24822)
diabetes mellitus
(MONDO_0005015)
Limited
ENHO
(HGNC:24838)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
CEP104
(HGNC:24866)
Joubert syndrome
(MONDO_0018772)
Strong
CCDC91
(HGNC:24855)
breast cancer
(MONDO_0007254)
Strong
MOGS
(HGNC:24862)
congenital disorder of glycosylation
(MONDO_0015286)
Moderate
YIPF5
(HGNC:24877)
neonatal diabetes mellitus
(MONDO_0016391)
Strong
PNPLA4
(HGNC:24887)
epilepsy
(MONDO_0005027)
Limited
CCDC47
(HGNC:24856)
trichohepatoneurodevelopmental syndrome
(MONDO_0032645)
Strong
OTUD4
(HGNC:24949)
breast cancer
(MONDO_0007254)
Limited
LARP7
(HGNC:24912)
microcephalic primordial dwarfism, Alazami type
(MONDO_0014031)
Strong
STBD1
(HGNC:24854)
Parkinson disease
(MONDO_0005180)
Strong
ZC4H2
(HGNC:24931)
Wieacker-Wolff syndrome
(MONDO_0010758)
Strong
GSX2
(HGNC:24959)
diencephalic-mesencephalic junction dysplasia
(MONDO_0017868)
Strong
OTUD4
(HGNC:24949)
prostate cancer
(MONDO_0008315)
Limited
HS1BP3
(HGNC:24979)
essential tremor
(MONDO_0003233)
Disputed
HS1BP3
(HGNC:24979)
Parkinson disease
(MONDO_0005180)
Disputed
EIF2AK1
(HGNC:24921)
autism
(MONDO_0005260)
Limited
HS1BP3
(HGNC:24979)
benign essential blepharospasm
(MONDO_0011728)
Limited
CFAP263
(HGNC:25002)
systemic sclerosis
(MONDO_0005100)
Strong
CFAP263
(HGNC:25002)
primary biliary cholangitis
(MONDO_0005388)
Strong
UBE2T
(HGNC:25009)
Fanconi anemia
(MONDO_0019391)
Strong
ASTE1
(HGNC:25021)
Lynch syndrome
(MONDO_0005835)
Strong
METTL5
(HGNC:25006)
intellectual disability
(MONDO_0001071)
Strong
SPICE1
(HGNC:25083)
sarcoidosis
(MONDO_0019338)
Limited
SGO1
(HGNC:25088)
gastric cancer
(MONDO_0001056)
Strong
AP5B1
(HGNC:25104)
sarcoidosis
(MONDO_0019338)
Limited
OTULIN
(HGNC:25118)
infantile-onset periodic fever-panniculitis-dermatosis syndrome
(MONDO_0014912)
Strong
LRSAM1
(HGNC:25135)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
GPRASP2
(HGNC:25169)
autism spectrum disorder
(MONDO_0005258)
Moderate
SPATA17
(HGNC:25184)
male infertility
(MONDO_0005372)
Limited
TMEM240
(HGNC:25186)
spinocerebellar ataxia type 21
(MONDO_0011833)
Strong
SGSM3
(HGNC:25228)
intellectual disability
(MONDO_0001071)
Strong
ANO6
(HGNC:25240)
Scott syndrome
(MONDO_0009885)
Strong
FBXL19
(HGNC:25300)
Alzheimer disease
(MONDO_0004975)
Strong
ANO6
(HGNC:25240)
ankylosing spondylitis
(MONDO_0005306)
Moderate
SHARPIN
(HGNC:25321)
Alzheimer disease
(MONDO_0004975)
Strong
NRK
(HGNC:25391)
Sotos syndrome
(MONDO_0019349)
Limited
FBXL19
(HGNC:25300)
psoriasis
(MONDO_0005083)
Strong
PIANP
(HGNC:25338)
intellectual disability
(MONDO_0001071)
Limited
TMTC2
(HGNC:25440)
OPTN-related open angle glaucoma
(MONDO_0100553)
Disputed
RAB40AL
(HGNC:25410)
deafness-intellectual disability, Martin-Probst type syndrome
(MONDO_0010353)
Disputed
TMTC2
(HGNC:25440)
sensorineural hearing loss disorder
(MONDO_0020678)
Strong
SAMD7
(HGNC:25394)
retinitis pigmentosa
(MONDO_0019200)
Limited
FAR2
(HGNC:25531)
intellectual disability
(MONDO_0001071)
Limited
PUS3
(HGNC:25461)
neurodevelopmental disorder
(MONDO_0700092)
Strong
MTPAP
(HGNC:25532)
spastic ataxia
(MONDO_0017845)
Strong
FAR2
(HGNC:25531)
Kallmann syndrome
(MONDO_0018800)
Limited
ENOX1
(HGNC:25474)
myasthenia gravis
(MONDO_0009688)
Moderate
TSR1
(HGNC:25542)
idiopathic spontaneous coronary artery dissection
(MONDO_0007385)
Strong
SLFN12
(HGNC:25500)
Sezary syndrome
(MONDO_0017844)
Limited
RFWD3
(HGNC:25539)
Fanconi anemia
(MONDO_0019391)
Moderate
CUL4B
(HGNC:2555)
X-linked intellectual disability, Cabezas type
(MONDO_0010306)
Strong
MSL2
(HGNC:25544)
autism spectrum disorder
(MONDO_0005258)
Strong
MSL2
(HGNC:25544)
neurodevelopmental disorder
(MONDO_0700092)
Strong
CUL4B
(HGNC:2555)
X-linked intellectual disability
(MONDO_0100284)
Strong
SMG8
(HGNC:25551)
Alzahrani-Kuwahara syndrome
(MONDO_0859136)
Strong
OGFOD1
(HGNC:25585)
Parkinson disease
(MONDO_0005180)
Limited
TMEM39A
(HGNC:25600)
multiple sclerosis
(MONDO_0005301)
Strong
ATAD3A
(HGNC:25567)
Harel-Yoon syndrome
(MONDO_0014958)
Strong
ACOXL
(HGNC:25621)
B-cell chronic lymphocytic leukemia
(MONDO_0004948)
Strong
WDR33
(HGNC:25651)
premature menopause
(MONDO_0001119)
Strong
GORAB
(HGNC:25676)
geroderma osteodysplastica
(MONDO_0009271)
Strong
KCTD17
(HGNC:25705)
myoclonic dystonia 11
(MONDO_0008044)
Strong
FN3KRP
(HGNC:25700)
type 2 diabetes mellitus
(MONDO_0005148)
Moderate
LAS1L
(HGNC:25726)
autosomal recessive distal spinal muscular atrophy 1
(MONDO_0011436)
Strong
LAS1L
(HGNC:25726)
X-linked intellectual disability
(MONDO_0100284)
Strong
MUL1
(HGNC:25762)
Parkinson disease
(MONDO_0005180)
Moderate
TCTN2
(HGNC:25774)
Meckel syndrome, type 1
(MONDO_0009571)
Strong
SMG9
(HGNC:25763)
heart and brain malformation syndrome
(MONDO_0014833)
Strong
TCTN2
(HGNC:25774)
Joubert syndrome
(MONDO_0018772)
Strong
MTHFSD
(HGNC:25778)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
USB1
(HGNC:25792)
poikiloderma with neutropenia
(MONDO_0011405)
Strong
USB1
(HGNC:25792)
dyskeratosis congenita
(MONDO_0015780)
Strong
SRD5A3
(HGNC:25812)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
CEP63
(HGNC:25815)
Seckel syndrome
(MONDO_0019342)
Strong
SYDE2
(HGNC:25841)
intellectual disability
(MONDO_0001071)
Limited
NAA60
(HGNC:25875)
basal ganglia calcification, idiopathic, 1
(MONDO_0024538)
Strong
FAM136A
(HGNC:25911)
Meniere disease
(MONDO_0007972)
Moderate
WDR73
(HGNC:25928)
Galloway-Mowat syndrome
(MONDO_0009627)
Strong
DEF8
(HGNC:25969)
skin squamous cell carcinoma
(MONDO_0002529)
Strong
DEF8
(HGNC:25969)
melanoma
(MONDO_0005105)
Strong
RNF186
(HGNC:25978)
ulcerative colitis
(MONDO_0005101)
Strong
PIGG
(HGNC:25985)
intellectual disability
(MONDO_0001071)
Strong
PIGG
(HGNC:25985)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
LAX1
(HGNC:26005)
systemic lupus erythematosus
(MONDO_0007915)
Strong
LAX1
(HGNC:26005)
rheumatoid arthritis
(MONDO_0008383)
Strong
SPDL1
(HGNC:26010)
prostate cancer
(MONDO_0008315)
Strong
SYBU
(HGNC:26011)
Parkinson disease
(MONDO_0005180)
Strong
KRBOX4
(HGNC:26007)
intellectual disability
(MONDO_0001071)
Limited
LAGE3
(HGNC:26058)
Galloway-Mowat syndrome
(MONDO_0009627)
Strong
CFAP69
(HGNC:26107)
male infertility
(MONDO_0005372)
Strong
DNAAF5
(HGNC:26013)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
TCTN1
(HGNC:26113)
Joubert syndrome
(MONDO_0018772)
Strong
EXO5
(HGNC:26115)
prostate cancer
(MONDO_0008315)
Strong
REEP4
(HGNC:26176)
dystonic disorder
(MONDO_0003441)
Limited
REEP4
(HGNC:26176)
benign essential blepharospasm
(MONDO_0011728)
Limited
ELMOD3
(HGNC:26158)
autism spectrum disorder
(MONDO_0005258)
Limited
REEP4
(HGNC:26176)
blepharospasm-oromandibular dystonia syndrome
(MONDO_0019772)
Limited
ZNF672
(HGNC:26179)
GLUT1 deficiency syndrome
(MONDO_0000188)
Disputed
CCDC134
(HGNC:26185)
osteogenesis imperfecta
(MONDO_0019019)
Strong
CSPP1
(HGNC:26193)
Joubert syndrome
(MONDO_0018772)
Strong
STEEP1
(HGNC:26239)
intellectual disability
(MONDO_0001071)
Strong
TMEM53
(HGNC:26186)
craniotubular dysplasia, Ikegawa type
(MONDO_0859226)
Strong
MYO19
(HGNC:26234)
hearing loss disorder
(MONDO_0005365)
Limited
NDNF
(HGNC:26256)
Kallmann syndrome
(MONDO_0018800)
Moderate
PLEKHS1
(HGNC:26285)
urinary bladder cancer
(MONDO_0001187)
Strong
CFAP54
(HGNC:26456)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
HENMT1
(HGNC:26400)
male infertility
(MONDO_0005372)
Moderate
TSNARE1
(HGNC:26437)
schizophrenia
(MONDO_0005090)
Strong
CFAP54
(HGNC:26456)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
CCDC122
(HGNC:26478)
leprosy
(MONDO_0005124)
Strong
KASH5
(HGNC:26520)
premature menopause
(MONDO_0001119)
Strong
ZNF513
(HGNC:26498)
hereditary gingival fibromatosis
(MONDO_0016070)
Strong
HSPB6
(HGNC:26511)
dilated cardiomyopathy
(MONDO_0005021)
Limited
VWA5B1
(HGNC:26538)
Alzheimer disease
(MONDO_0004975)
Strong
HYLS1
(HGNC:26558)
hydrolethalus syndrome
(MONDO_0006037)
Strong
ZFYVE27
(HGNC:26559)
hereditary spastic paraplegia
(MONDO_0019064)
Limited
ODAD1
(HGNC:26560)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
HYLS1
(HGNC:26558)
Joubert syndrome
(MONDO_0018772)
Strong
TERB1
(HGNC:26675)
female infertility
(MONDO_0021124)
Limited
MLKL
(HGNC:26617)
Alzheimer disease
(MONDO_0004975)
Moderate
ANKS6
(HGNC:26724)
nephronophthisis
(MONDO_0019005)
Strong
CCDC116
(HGNC:26688)
lung cancer
(MONDO_0008903)
Strong
TYW5
(HGNC:26754)
schizophrenia
(MONDO_0005090)
Strong
ANKRD31
(HGNC:26853)
premature menopause
(MONDO_0001119)
Moderate
CKAP2L
(HGNC:26877)
Filippi syndrome
(MONDO_0010092)
Strong
FAM241A
(HGNC:26813)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
ERCC6L2
(HGNC:26922)
pancytopenia
(MONDO_0001529)
Strong
TAPT1
(HGNC:26887)
osteogenesis imperfecta
(MONDO_0019019)
Strong
JAGN1
(HGNC:26926)
severe congenital neutropenia
(MONDO_0018542)
Strong
FOXRED1
(HGNC:26927)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
UFC1
(HGNC:26941)
intellectual disability
(MONDO_0001071)
Strong
UFC1
(HGNC:26941)
neurodevelopmental disorder
(MONDO_0700092)
Limited
GSTT4
(HGNC:26930)
velocardiofacial syndrome
(MONDO_0008644)
Limited
GPCPD1
(HGNC:26957)
2q37 microdeletion syndrome
(MONDO_0010886)
Limited
C10orf71
(HGNC:26973)
dilated cardiomyopathy
(MONDO_0005021)
Strong
SPNS2
(HGNC:26992)
hearing loss disorder
(MONDO_0005365)
Moderate
ZNF816
(HGNC:26995)
psoriasis
(MONDO_0005083)
Strong
CMPK2
(HGNC:27015)
basal ganglia calcification, idiopathic, 1
(MONDO_0024538)
Strong
ZNF827
(HGNC:27193)
Hirschsprung disease
(MONDO_0018309)
Limited
ZNF827
(HGNC:27193)
Sotos syndrome
(MONDO_0019349)
Limited
IDO2
(HGNC:27269)
sarcoidosis
(MONDO_0019338)
Limited
ZCCHC12
(HGNC:27273)
intellectual disability
(MONDO_0001071)
Disputed
MPZL3
(HGNC:27279)
lung cancer
(MONDO_0008903)
Strong
CRTC2
(HGNC:27301)
non-small cell lung carcinoma
(MONDO_0005233)
Limited
CRTC2
(HGNC:27301)
lung cancer
(MONDO_0008903)
Limited
DDT
(HGNC:2732)
velocardiofacial syndrome
(MONDO_0008644)
Limited
PDILT
(HGNC:27338)
nephrolithiasis
(MONDO_0008171)
Strong
DDX11
(HGNC:2736)
Warsaw breakage syndrome
(MONDO_0013252)
Strong
DHX15
(HGNC:2738)
acute myeloid leukemia
(MONDO_0018874)
Strong
TSEN54
(HGNC:27561)
pontocerebellar hypoplasia
(MONDO_0020135)
Strong
DEFA5
(HGNC:2764)
Crohn disease
(MONDO_0005011)
Moderate
EMC10
(HGNC:27609)
intellectual disability
(MONDO_0001071)
Strong
DEFA6
(HGNC:2765)
Crohn disease
(MONDO_0005011)
Limited
DFFB
(HGNC:2773)
polycystic ovary syndrome
(MONDO_0008487)
Limited
SLC6A19
(HGNC:27960)
Hartnup disease
(MONDO_0009324)
Strong
ZNF517
(HGNC:27984)
Zimmermann-Laband syndrome
(MONDO_0000200)
Limited
ZNF517
(HGNC:27984)
Temple-Baraitser syndrome
(MONDO_0012735)
Limited
MARCHF2
(HGNC:28038)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
BBIP1
(HGNC:28093)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
ADRA1D
(HGNC:280)
gastroparesis
(MONDO_0006769)
Strong
UBLCP1
(HGNC:28110)
psoriasis
(MONDO_0005083)
Strong
PIGY
(HGNC:28213)
congenital disorder of glycosylation
(MONDO_0015286)
Moderate
ZXDC
(HGNC:28160)
acquired polycythemia vera
(MONDO_0009891)
Limited
UTP23
(HGNC:28224)
colorectal cancer
(MONDO_0005575)
Strong
TLCD5
(HGNC:28280)
exfoliation syndrome
(MONDO_0008327)
Limited
MIEN1
(HGNC:28230)
breast cancer
(MONDO_0007254)
Limited
CCDC32
(HGNC:28295)
cardiofacioneurodevelopmental syndrome
(MONDO_0030873)
Strong
CHCHD7
(HGNC:28314)
pleomorphic adenoma
(MONDO_0008401)
Moderate
HORMAD2
(HGNC:28383)
IgA glomerulonephritis
(MONDO_0005342)
Moderate
WBP2NL
(HGNC:28389)
breast cancer
(MONDO_0007254)
Moderate
THOC6
(HGNC:28369)
THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome
(MONDO_0013362)
Strong
TSEN2
(HGNC:28422)
pontocerebellar hypoplasia
(MONDO_0020135)
Strong
STAC3
(HGNC:28423)
Bailey-Bloch congenital myopathy
(MONDO_0009722)
Strong
TSEN2
(HGNC:28422)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Strong
DGCR2
(HGNC:2845)
schizophrenia
(MONDO_0005090)
Limited
POLR3GL
(HGNC:28466)
Wiedemann-Rautenstrauch syndrome
(MONDO_0009910)
Moderate
HROB
(HGNC:28460)
premature menopause
(MONDO_0001119)
Strong
MRI1
(HGNC:28469)
ventricular septal defect
(MONDO_0002070)
Strong
CCNQ
(HGNC:28434)
syndactyly-telecanthus-anogenital and renal malformations syndrome
(MONDO_0010408)
Strong
TMEM151A
(HGNC:28497)
episodic kinesigenic dyskinesia
(MONDO_0044202)
Strong
DGKD
(HGNC:2851)
rheumatoid arthritis
(MONDO_0008383)
Limited
DGKD
(HGNC:2851)
systemic lupus erythematosus
(MONDO_0007915)
Limited
METTL16
(HGNC:28484)
colorectal cancer
(MONDO_0005575)
Moderate
CYBC1
(HGNC:28672)
chronic granulomatous disease
(MONDO_0018305)
Strong
SCARA5
(HGNC:28701)
von Willebrand disease (hereditary or acquired)
(MONDO_0024574)
Limited
CNIH2
(HGNC:28744)
gout
(MONDO_0005393)
Strong
SHLD2
(HGNC:28773)
gout
(MONDO_0005393)
Limited
DIAPH2
(HGNC:2877)
premature menopause
(MONDO_0001119)
Limited
DIAPH2
(HGNC:2877)
laryngeal squamous cell carcinoma
(MONDO_0005595)
Moderate
KIAA0825
(HGNC:28532)
postaxial polydactyly
(MONDO_0020927)
Strong
SYCE1
(HGNC:28852)
premature menopause
(MONDO_0001119)
Strong
MDFIC
(HGNC:28870)
lymphatic malformation 12
(MONDO_0031043)
Strong
DAGLB
(HGNC:28923)
autism
(MONDO_0005260)
Limited
P4HTM
(HGNC:28858)
severe intellectual disability-hypotonia-strabismus-coarse face-planovalgus syndrome
(MONDO_0018572)
Strong
TBC1D21
(HGNC:28536)
exfoliation syndrome
(MONDO_0008327)
Strong
KIAA0040
(HGNC:28950)
alcohol dependence
(MONDO_0007079)
Moderate
ZNF646
(HGNC:29004)
Parkinson disease
(MONDO_0005180)
Limited
GARRE1
(HGNC:29016)
primary myelofibrosis
(MONDO_0009692)
Limited
DLAT
(HGNC:2896)
pyruvate dehydrogenase deficiency
(MONDO_0019169)
Strong
SGSM2
(HGNC:29026)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
SFI1
(HGNC:29064)
breast cancer
(MONDO_0007254)
Limited
IQCK
(HGNC:28556)
Alzheimer disease
(MONDO_0004975)
Strong
DGKQ
(HGNC:2856)
Parkinson disease
(MONDO_0005180)
Limited
SFI1
(HGNC:29064)
prostate cancer
(MONDO_0008315)
Limited
DLGAP2
(HGNC:2906)
autism spectrum disorder
(MONDO_0005258)
Limited
SFI1
(HGNC:29064)
uterine corpus leiomyoma
(MONDO_0007886)
Limited
DNAAF6
(HGNC:28570)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
CYBC1
(HGNC:28672)
inflammatory bowel disease
(MONDO_0005265)
Strong
PROCA1
(HGNC:28600)
intellectual disability
(MONDO_0001071)
Limited
ZNF577
(HGNC:28673)
breast cancer
(MONDO_0007254)
Limited
DHCR24
(HGNC:2859)
desmosterolosis
(MONDO_0011217)
Strong
CABCOCO1
(HGNC:28678)
hypertensive disorder
(MONDO_0005044)
Strong
CABCOCO1
(HGNC:28678)
cardiovascular disorder
(MONDO_0004995)
Strong
VWA8
(HGNC:29071)
systemic lupus erythematosus
(MONDO_0007915)
Limited
VWA8
(HGNC:29071)
retinitis pigmentosa
(MONDO_0019200)
Strong
ENTREP2
(HGNC:29075)
age-related macular degeneration
(MONDO_0005150)
Limited
VWA8
(HGNC:29071)
rheumatoid arthritis
(MONDO_0008383)
Limited
PDS5A
(HGNC:29088)
Cornelia de Lange syndrome
(MONDO_0016033)
Strong
DLL3
(HGNC:2909)
spondylocostal dysostosis
(MONDO_0000359)
Strong
TESPA1
(HGNC:29109)
rheumatoid arthritis
(MONDO_0008383)
Limited
TESPA1
(HGNC:29109)
systemic lupus erythematosus
(MONDO_0007915)
Strong
DLL4
(HGNC:2910)
Adams-Oliver syndrome
(MONDO_0007034)
Strong
DENND3
(HGNC:29134)
hereditary hemochromatosis
(MONDO_0006507)
Strong
DLX3
(HGNC:2916)
tricho-dento-osseous syndrome
(MONDO_0008592)
Strong
IQCE
(HGNC:29171)
polydactyly
(MONDO_0021003)
Strong
KAZN
(HGNC:29173)
endometriosis
(MONDO_0005133)
Moderate
KDM4B
(HGNC:29136)
corpus callosum, agenesis of
(MONDO_0009022)
Moderate
TCF25
(HGNC:29181)
dementia
(MONDO_0001627)
Moderate
TCF25
(HGNC:29181)
cerebrovascular disorder
(MONDO_0011057)
Limited
PLCH1
(HGNC:29185)
holoprosencephaly
(MONDO_0016296)
Strong
ZNF512B
(HGNC:29212)
amyotrophic lateral sclerosis
(MONDO_0004976)
Disputed
BAHCC1
(HGNC:29279)
spinal muscular atrophy
(MONDO_0001516)
Disputed
ARHGAP31
(HGNC:29216)
Adams-Oliver syndrome
(MONDO_0007034)
Strong
SH3PXD2B
(HGNC:29242)
Frank-Ter Haar syndrome
(MONDO_0009579)
Strong
GRAMD1B
(HGNC:29214)
multiple sclerosis
(MONDO_0005301)
Strong
ADSS2
(HGNC:292)
schizophrenia
(MONDO_0005090)
Disputed
FBRSL1
(HGNC:29308)
Parkinson disease
(MONDO_0005180)
Limited
ZDBF2
(HGNC:29313)
nasopalpebral lipoma-coloboma syndrome
(MONDO_0008182)
Limited
ZSWIM6
(HGNC:29316)
acromelic frontonasal dysostosis
(MONDO_0011359)
Strong
THSD7B
(HGNC:29348)
lung adenocarcinoma
(MONDO_0005061)
Limited
KLHL15
(HGNC:29347)
X-linked intellectual disability
(MONDO_0100284)
Strong
THSD7B
(HGNC:29348)
lung cancer
(MONDO_0008903)
Limited
FHIP2A
(HGNC:29320)
intellectual disability
(MONDO_0001071)
Limited
ZNF518B
(HGNC:29365)
gout
(MONDO_0005393)
Strong
ZNF526
(HGNC:29415)
Dentici-Novelli neurodevelopmental syndrome
(MONDO_0859251)
Moderate
EARS2
(HGNC:29419)
leukoencephalopathy-thalamus and brainstem anomalies-high lactate syndrome
(MONDO_0013971)
Strong
RSPRY1
(HGNC:29420)
spondyloepimetaphyseal dysplasia
(MONDO_0100510)
Strong
CCBE1
(HGNC:29426)
Hennekam syndrome
(MONDO_0016256)
Strong
DNAH12
(HGNC:2943)
gastric adenocarcinoma
(MONDO_0005036)
Limited
KIF2B
(HGNC:29443)
obesity disorder
(MONDO_0011122)
Moderate
GLIS2
(HGNC:29450)
nephronophthisis
(MONDO_0019005)
Strong
LCE3B
(HGNC:29462)
psoriasis
(MONDO_0005083)
Moderate
GPSM2
(HGNC:29501)
Chudley-McCullough syndrome
(MONDO_0011411)
Strong
C12orf57
(HGNC:29521)
temtamy syndrome
(MONDO_0009033)
Strong
MTF2
(HGNC:29535)
Parkinson disease
(MONDO_0005180)
Strong
MAPKBP1
(HGNC:29536)
nephronophthisis
(MONDO_0019005)
Strong
NEXN
(HGNC:29557)
dilated cardiomyopathy
(MONDO_0005021)
Strong
PLPPR2
(HGNC:29566)
camptodactyly-arthropathy-coxa vara-pericarditis syndrome
(MONDO_0008828)
Strong
LSR
(HGNC:29572)
Alzheimer disease
(MONDO_0004975)
Strong
MAN2B2
(HGNC:29623)
congenital disorder of glycosylation
(MONDO_0015286)
Limited
DYNC1I2
(HGNC:2964)
Beckwith-Wiedemann syndrome
(MONDO_0007534)
Limited
MESP1
(HGNC:29658)
ventricular septal defect
(MONDO_0002070)
Strong
MESP1
(HGNC:29658)
congenital heart disease
(MONDO_0005453)
Strong
MTFMT
(HGNC:29666)
Leigh syndrome
(MONDO_0009723)
Strong
SLC25A32
(HGNC:29683)
multiple acyl-CoA dehydrogenase deficiency
(MONDO_0009282)
Strong
SLC25A37
(HGNC:29786)
multiple sclerosis
(MONDO_0005301)
Limited
TOP1MT
(HGNC:29787)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
MUS81
(HGNC:29814)
breast cancer
(MONDO_0007254)
Strong
GFM2
(HGNC:29682)
Leigh syndrome
(MONDO_0009723)
Strong
MAP3K21
(HGNC:29798)
colorectal cancer
(MONDO_0005575)
Strong
MRTFB
(HGNC:29819)
autism
(MONDO_0005260)
Limited
NAT10
(HGNC:29830)
schizophrenia
(MONDO_0005090)
Limited
N4BP1
(HGNC:29850)
schizophrenia
(MONDO_0005090)
Limited
DNTT
(HGNC:2983)
acute lymphoblastic leukemia
(MONDO_0004967)
Limited
DOC2A
(HGNC:2985)
schizophrenia
(MONDO_0005090)
Strong
UBAP2L
(HGNC:29877)
neurodevelopmental disorder with impaired language, behavioral abnormalities, and dysmorphic facies
(MONDO_0957588)
Strong
CD300LF
(HGNC:29883)
autism spectrum disorder
(MONDO_0005258)
Limited
ISCU
(HGNC:29882)
hereditary myopathy with lactic acidosis due to ISCU deficiency
(MONDO_0009706)
Strong
NLRP2B
(HGNC:29887)
ovarian cancer
(MONDO_0008170)
Limited
CALCOCO2
(HGNC:29912)
Crohn disease
(MONDO_0005011)
Strong
MDM1
(HGNC:29917)
intellectual disability
(MONDO_0001071)
Limited
CALCOCO2
(HGNC:29912)
ulcerative colitis
(MONDO_0005101)
Strong
MDM1
(HGNC:29917)
neurodevelopmental disorder
(MONDO_0700092)
Limited
NUP37
(HGNC:29929)
cardiovascular disorder
(MONDO_0004995)
Limited
NUP37
(HGNC:29929)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
COASY
(HGNC:29932)
neurodegeneration with brain iron accumulation
(MONDO_0018307)
Strong
CCDC65
(HGNC:29937)
primary ciliary dyskinesia
(MONDO_0016575)
Moderate
GATAD1
(HGNC:29941)
dilated cardiomyopathy
(MONDO_0005021)
Strong
OIT3
(HGNC:29953)
gout
(MONDO_0005393)
Limited
RHOXF1
(HGNC:29993)
oligospermia
(MONDO_0001913)
Strong
RHOXF1
(HGNC:29993)
male infertility
(MONDO_0005372)
Strong
RHOXF1
(HGNC:29993)
azoospermia
(MONDO_0100459)
Strong
PGLYRP4
(HGNC:30015)
Parkinson disease
(MONDO_0005180)
Strong
REEP6
(HGNC:30078)
retinitis pigmentosa
(MONDO_0019200)
Strong
ATAD2
(HGNC:30123)
lung cancer
(MONDO_0008903)
Moderate
LZTS3
(HGNC:30139)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
TBKBP1
(HGNC:30140)
ankylosing spondylitis
(MONDO_0005306)
Strong
ZFAND6
(HGNC:30164)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
PCP2
(HGNC:30209)
relapsing polychondritis
(MONDO_0019125)
Limited
TUSC3
(HGNC:30242)
intellectual disability
(MONDO_0001071)
Strong
RALGPS2
(HGNC:30279)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
PYGO2
(HGNC:30257)
male infertility
(MONDO_0005372)
Strong
PYGO2
(HGNC:30257)
azoospermia
(MONDO_0100459)
Moderate
AEBP1
(HGNC:303)
Ehlers-Danlos syndrome
(MONDO_0020066)
Strong
RGL1
(HGNC:30281)
intellectual disability
(MONDO_0001071)
Limited
LEO1
(HGNC:30401)
neurodevelopmental disorder
(MONDO_0700092)
Strong
RBM47
(HGNC:30358)
type 1 diabetes mellitus
(MONDO_0005147)
Strong
LRIF1
(HGNC:30299)
facioscapulohumeral muscular dystrophy
(MONDO_0001347)
Strong
PHB2
(HGNC:30306)
chronic granulomatous disease
(MONDO_0018305)
Limited
SPPL3
(HGNC:30424)
systemic sclerosis
(MONDO_0005100)
Strong
SPPL3
(HGNC:30424)
primary biliary cholangitis
(MONDO_0005388)
Strong
SH2D6
(HGNC:30439)
autism spectrum disorder
(MONDO_0005258)
Limited
PSMG1
(HGNC:3043)
Crohn disease
(MONDO_0005011)
Strong
PSMG1
(HGNC:3043)
ulcerative colitis
(MONDO_0005101)
Strong
PSMG1
(HGNC:3043)
inflammatory bowel disease
(MONDO_0005265)
Limited
KLHL40
(HGNC:30372)
nemaline myopathy
(MONDO_0018958)
Strong
RCCD1
(HGNC:30457)
exocrine pancreatic carcinoma
(MONDO_0005192)
Strong
UBR3
(HGNC:30467)
neurodevelopmental disorder
(MONDO_0700092)
Strong
RCCD1
(HGNC:30457)
breast cancer
(MONDO_0007254)
Strong
TMEM147
(HGNC:30414)
intellectual disability
(MONDO_0001071)
Limited
PCMTD1
(HGNC:30483)
primary angle-closure glaucoma
(MONDO_0001868)
Limited
IFT172
(HGNC:30391)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
DSG1
(HGNC:3048)
severe dermatitis-multiple allergies-metabolic wasting syndrome
(MONDO_0014218)
Strong
DNAAF3
(HGNC:30492)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
DSG1
(HGNC:3048)
striate palmoplantar keratoderma
(MONDO_0018865)
Strong
DNAJC19
(HGNC:30528)
3-methylglutaconic aciduria type 5
(MONDO_0012435)
Strong
EPYC
(HGNC:3053)
posterior amorphous corneal dystrophy
(MONDO_0013027)
Limited
TADA1
(HGNC:30631)
intellectual disability
(MONDO_0001071)
Limited
SUSD2
(HGNC:30667)
myocardial ischemia
(MONDO_0024644)
Strong
SEPSECS
(HGNC:30605)
pontocerebellar hypoplasia type 2D
(MONDO_0013438)
Strong
SV2C
(HGNC:30670)
Parkinson disease
(MONDO_0005180)
Strong
CAND2
(HGNC:30689)
atrial fibrillation
(MONDO_0004981)
Strong
TARS2
(HGNC:30740)
combined oxidative phosphorylation defect type 21
(MONDO_0014398)
Strong
TTC21A
(HGNC:30761)
male infertility
(MONDO_0005372)
Strong
GTF2IRD2
(HGNC:30775)
Williams syndrome
(MONDO_0008678)
Strong
TRAIP
(HGNC:30764)
Seckel syndrome 9
(MONDO_0014767)
Limited
CDCA7L
(HGNC:30777)
plasma cell myeloma
(MONDO_0009693)
Strong
UBIAD1
(HGNC:30791)
Schnyder corneal dystrophy
(MONDO_0007374)
Strong
TSPAN11
(HGNC:30795)
intellectual disability
(MONDO_0001071)
Limited
TSPAN11
(HGNC:30795)
Kallmann syndrome
(MONDO_0018800)
Limited
PRRG4
(HGNC:30799)
WAGR syndrome
(MONDO_0008681)
Strong
PRSS55
(HGNC:30824)
prostate cancer
(MONDO_0008315)
Strong
TDRD7
(HGNC:30831)
glaucoma
(MONDO_0005041)
Moderate
SEZ6L2
(HGNC:30844)
autism
(MONDO_0005260)
Limited
POC1B
(HGNC:30836)
cone dystrophy
(MONDO_0000455)
Strong
DVL1
(HGNC:3084)
Robinow syndrome
(MONDO_0019978)
Strong
TBC1D31
(HGNC:30888)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Moderate
VWA1
(HGNC:30910)
neuromuscular disease
(MONDO_0019056)
Strong
ZC3H7A
(HGNC:30959)
pancreatic ductal adenocarcinoma
(MONDO_0005184)
Limited
YY1AP1
(HGNC:30935)
grange syndrome
(MONDO_0011243)
Strong
OR2T35
(HGNC:31257)
ovarian carcinoma
(MONDO_0005140)
Limited
SLC16A13
(HGNC:31037)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
OR2T35
(HGNC:31257)
xeroderma pigmentosum group C
(MONDO_0010211)
Limited
HAPLN4
(HGNC:31357)
essential tremor
(MONDO_0003233)
Limited
S1PR3
(HGNC:3167)
neurocutaneous melanocytosis
(MONDO_0009578)
Limited
BOD1L1
(HGNC:31792)
premature menopause
(MONDO_0001119)
Moderate
TRIM67
(HGNC:31859)
hypospadias
(MONDO_0005345)
Limited
PHC1
(HGNC:3182)
autosomal recessive primary microcephaly
(MONDO_0016660)
Strong
AGA
(HGNC:318)
aspartylglucosaminuria
(MONDO_0008830)
Strong
NBEAL2
(HGNC:31928)
gray platelet syndrome
(MONDO_0007686)
Strong
EEF1B2
(HGNC:3208)
intellectual disability
(MONDO_0001071)
Strong
SYNDIG1L
(HGNC:32388)
Alzheimer disease
(MONDO_0004975)
Moderate
EHD3
(HGNC:3244)
major depressive disorder
(MONDO_0002009)
Limited
ALG11
(HGNC:32456)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
PRCD
(HGNC:32528)
retinitis pigmentosa
(MONDO_0019200)
Strong
GFRAL
(HGNC:32789)
anorexia nervosa
(MONDO_0005351)
Limited
TRIM71
(HGNC:32669)
congenital hydrocephalus
(MONDO_0016349)
Strong
EIF4EBP3
(HGNC:3290)
colorectal cancer
(MONDO_0005575)
Limited
NKX2-6
(HGNC:32940)
congenital heart disease
(MONDO_0005453)
Strong
AGRP
(HGNC:330)
morbid obesity
(MONDO_0005139)
Disputed
NKX2-6
(HGNC:32940)
persistent truncus arteriosus
(MONDO_0018072)
Strong
AGRP
(HGNC:330)
obesity disorder
(MONDO_0011122)
Strong
ELFN1
(HGNC:33154)
restless legs syndrome
(MONDO_0005391)
Strong
ELAVL4
(HGNC:3315)
Parkinson disease
(MONDO_0005180)
Strong
CTTN
(HGNC:3338)
esophageal squamous cell carcinoma
(MONDO_0005580)
Moderate
EXOG
(HGNC:3347)
pseudomyxoma peritonei
(MONDO_0017048)
Limited
GSTT2B
(HGNC:33437)
velocardiofacial syndrome
(MONDO_0008644)
Limited
ATRIP
(HGNC:33499)
Seckel syndrome
(MONDO_0019342)
Strong
NDUFAF8
(HGNC:33551)
mitochondrial complex I deficiency
(MONDO_0100133)
Limited
CCDC61
(HGNC:33629)
relapsing polychondritis
(MONDO_0019125)
Limited
C2CD4A
(HGNC:33627)
type 2 diabetes mellitus
(MONDO_0005148)
Moderate
MYMK
(HGNC:33778)
Carey-Fineman-Ziter syndrome
(MONDO_0031415)
Strong
FAM174B
(HGNC:34339)
schizophrenia
(MONDO_0005090)
Limited
C2orf80
(HGNC:34352)
glioma
(MONDO_0021042)
Strong
USP17L2
(HGNC:34434)
endometriosis
(MONDO_0005133)
Limited
FABP12
(HGNC:34524)
familial multiple trichoepithelioma
(MONDO_0011114)
Limited
FABP12
(HGNC:34524)
Marie Unna hereditary hypotrichosis
(MONDO_0018631)
Limited
IGLON5
(HGNC:34550)
autoimmune encephalopathy with parasomnia and obstructive sleep apnea
(MONDO_0018489)
Strong
ESD
(HGNC:3465)
Wilson disease
(MONDO_0010200)
Strong
EVI5
(HGNC:3501)
multiple sclerosis
(MONDO_0005301)
Strong
ESRRG
(HGNC:3474)
breast cancer
(MONDO_0007254)
Moderate
FOXI3
(HGNC:35123)
craniofacial microsomia
(MONDO_0015397)
Strong
EML6
(HGNC:35412)
keratoconus
(MONDO_0015486)
Strong
FAH
(HGNC:3579)
tyrosinemia type I
(MONDO_0010161)
Strong
FCGRT
(HGNC:3621)
breast cancer
(MONDO_0007254)
Limited
FCGRT
(HGNC:3621)
colon carcinoma
(MONDO_0002032)
Limited
FCGRT
(HGNC:3621)
uterine corpus leiomyoma
(MONDO_0007886)
Limited
FCGRT
(HGNC:3621)
prostate cancer
(MONDO_0008315)
Limited
FDX1
(HGNC:3638)
IgA glomerulonephritis
(MONDO_0005342)
Limited
FEM1B
(HGNC:3649)
polycystic ovary syndrome
(MONDO_0008487)
Moderate
KBTBD13
(HGNC:37227)
nemaline myopathy
(MONDO_0018958)
Strong
KBTBD13
(HGNC:37227)
nemaline myopathy 6
(MONDO_0012237)
Strong
KBTBD13
(HGNC:37227)
congenital myopathy
(MONDO_0019952)
Moderate
FLRT3
(HGNC:3762)
congenital hypogonadotropic hypogonadism
(MONDO_0015770)
Limited
FOXD2
(HGNC:3803)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Strong
CENPI
(HGNC:3968)
nephrotic syndrome
(MONDO_0005377)
Limited
CENPI
(HGNC:3968)
nephrotic syndrome of childhood - steroid sensitive
(MONDO_0044781)
Strong
FSTL1
(HGNC:3972)
congenital heart disease
(MONDO_0005453)
Limited
MUC22
(HGNC:39755)
asthma
(MONDO_0004979)
Strong
PET100
(HGNC:40038)
mitochondrial disease
(MONDO_0044970)
Limited
PET100
(HGNC:40038)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Strong
MCIDAS
(HGNC:40050)
primary ciliary dyskinesia
(MONDO_0016575)
Moderate
FUT7
(HGNC:4018)
hereditary multiple osteochondromas
(MONDO_0005508)
Strong
FZD7
(HGNC:4045)
Lynch syndrome
(MONDO_0005835)
Limited
FZD7
(HGNC:4045)
classic familial adenomatous polyposis
(MONDO_0021055)
Limited
GALE
(HGNC:4116)
galactosemia
(MONDO_0018116)
Strong
ALDH4A1
(HGNC:406)
hyperprolinemia type 2
(MONDO_0009401)
Strong
ALDOA
(HGNC:414)
hereditary fructose intolerance
(MONDO_0009249)
Strong
ALDOC
(HGNC:418)
hereditary fructose intolerance
(MONDO_0009249)
Limited
GDF10
(HGNC:4215)
rectal cancer
(MONDO_0006519)
Strong
GDF10
(HGNC:4215)
colon carcinoma
(MONDO_0002032)
Strong
GDF7
(HGNC:4222)
Barrett esophagus
(MONDO_0013662)
Strong
GDF7
(HGNC:4222)
esophageal adenocarcinoma
(MONDO_0005028)
Strong
GFI1
(HGNC:4237)
severe congenital neutropenia
(MONDO_0018542)
Strong
CBLIF
(HGNC:4268)
hemolytic-uremic syndrome
(MONDO_0001549)
Strong
GFPT2
(HGNC:4242)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
CBLIF
(HGNC:4268)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Strong
GMDS
(HGNC:4369)
OPTN-related open angle glaucoma
(MONDO_0100553)
Strong
GLP2R
(HGNC:4325)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
GNAT1
(HGNC:4393)
congenital stationary night blindness
(MONDO_0016293)
Strong
GNAZ
(HGNC:4395)
neurofibromatosis type 1
(MONDO_0018975)
Limited
GNGT2
(HGNC:4412)
refractive error
(MONDO_0004892)
Limited
GNAI3
(HGNC:4387)
auriculocondylar syndrome
(MONDO_0000107)
Strong
GNPAT
(HGNC:4416)
rhizomelic chondrodysplasia punctata
(MONDO_0015776)
Strong
GNMT
(HGNC:4415)
guanidinoacetate methyltransferase deficiency
(MONDO_0012999)
Strong
GNGT2
(HGNC:4412)
glaucoma
(MONDO_0005041)
Limited
GNRH2
(HGNC:4420)
osteosarcoma
(MONDO_0009807)
Moderate
GNS
(HGNC:4422)
mucopolysaccharidosis type 3D
(MONDO_0009658)
Strong
GNGT2
(HGNC:4412)
myopic macular degeneration
(MONDO_0015807)
Limited
GPR3
(HGNC:4484)
premature menopause
(MONDO_0001119)
Limited
GPR55
(HGNC:4511)
anorexia nervosa
(MONDO_0005351)
Limited
GPR4
(HGNC:4497)
arteriovenous hemangioma/malformation
(MONDO_0001256)
Strong
FFAR1
(HGNC:4498)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
C5AR2
(HGNC:4527)
coronary artery disorder
(MONDO_0005010)
Strong
C5AR2
(HGNC:4527)
hyperlipidemia, familial combined, LPL related
(MONDO_0007759)
Limited
SUCNR1
(HGNC:4542)
colorectal cancer
(MONDO_0005575)
Limited
AMBN
(HGNC:452)
amelogenesis imperfecta
(MONDO_0019507)
Strong
GPX5
(HGNC:4557)
abdominal obesity-metabolic syndrome
(MONDO_0000816)
Strong
TECR
(HGNC:4551)
intellectual disability
(MONDO_0001071)
Strong
GPX5
(HGNC:4557)
diabetes mellitus
(MONDO_0005015)
Limited
GPX5
(HGNC:4557)
obesity disorder
(MONDO_0011122)
Limited
GSPT1
(HGNC:4621)
lung cancer
(MONDO_0008903)
Limited
GSPT2
(HGNC:4622)
intellectual disability
(MONDO_0001071)
Strong
GTF2E2
(HGNC:4651)
trichothiodystrophy
(MONDO_0018053)
Strong
GTF3C5
(HGNC:4668)
type 1 diabetes mellitus
(MONDO_0005147)
Strong
GUCY1B1
(HGNC:4687)
hypertensive disorder
(MONDO_0005044)
Strong
GYG2
(HGNC:4700)
glycogen storage disease II
(MONDO_0009290)
Limited
GTPBP2
(HGNC:4670)
Jaberi-Elahi syndrome
(MONDO_0060711)
Strong
GYG2
(HGNC:4700)
Leigh syndrome
(MONDO_0009723)
Limited
H2BC15 Gene
(HGNC:4749)
prostate cancer
(MONDO_0008315)
Moderate
HARS2
(HGNC:4817)
Perrault syndrome
(MONDO_0017312)
Strong
HCCS
(HGNC:4837)
linear skin defects with multiple congenital anomalies 1
(MONDO_0024552)
Strong
ANGPTL2
(HGNC:490)
Schimke immuno-osseous dysplasia
(MONDO_0009458)
Strong
HK3
(HGNC:4925)
premature menopause
(MONDO_0001119)
Limited
HLX
(HGNC:4978)
congenital diaphragmatic hernia
(MONDO_0005711)
Limited
RIPK4
(HGNC:496)
Bartsocas-Papas syndrome 1
(MONDO_0009901)
Strong
HNRNPH3
(HGNC:5043)
salivary duct carcinoma
(MONDO_0044915)
Limited
HOXA4
(HGNC:5105)
lung adenocarcinoma
(MONDO_0005061)
Limited
HNRNPK
(HGNC:5044)
Au-Kline syndrome
(MONDO_0014700)
Strong
HOXA4
(HGNC:5105)
hypospadias
(MONDO_0005345)
Moderate
HOXA7
(HGNC:5108)
acute myeloid leukemia
(MONDO_0018874)
Moderate
HOXB4
(HGNC:5115)
acute myeloid leukemia
(MONDO_0018874)
Strong
HOXB6
(HGNC:5117)
hypospadias
(MONDO_0005345)
Limited
HOXB7
(HGNC:5118)
neural tube defect
(MONDO_0018075)
Moderate
HOXD1
(HGNC:5132)
ovarian cancer
(MONDO_0008170)
Limited
HPD
(HGNC:5147)
hawkinsinuria
(MONDO_0007700)
Strong
HPD
(HGNC:5147)
tyrosinemia type III
(MONDO_0010162)
Strong
HPX
(HGNC:5171)
hemochromatosis type 1
(MONDO_0021001)
Limited
GSG1L2
(HGNC:51826)
neurodevelopmental disorder
(MONDO_0700092)
Limited
KRR1
(HGNC:5176)
polycystic ovary syndrome
(MONDO_0008487)
Moderate
HS3ST1
(HGNC:5194)
cardiovascular disorder
(MONDO_0004995)
Strong
HS3ST1
(HGNC:5194)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
HSPA6
(HGNC:5239)
EAST syndrome
(MONDO_0013005)
Limited
HSPA9
(HGNC:5244)
even-plus syndrome
(MONDO_0014801)
Strong
HSPB3
(HGNC:5248)
Charcot-Marie-Tooth disease type 2
(MONDO_0018993)
Strong
HTR1E
(HGNC:5291)
attention deficit-hyperactivity disorder
(MONDO_0007743)
Moderate
IDH3A
(HGNC:5384)
retinitis pigmentosa
(MONDO_0019200)
Strong
IFNA17
(HGNC:5422)
sarcoidosis
(MONDO_0019338)
Disputed
ID3
(HGNC:5362)
Burkitt lymphoma
(MONDO_0007243)
Strong
IGFBP6
(HGNC:5475)
intervertebral disk degenerative disorder
(MONDO_0011385)
Limited
IFI35
(HGNC:5399)
acute myeloid leukemia
(MONDO_0018874)
Limited
AP1S1
(HGNC:559)
MEDNIK syndrome
(MONDO_0012251)
Strong
AP1S2
(HGNC:560)
X-linked intellectual disability
(MONDO_0100284)
Strong
AP3S2
(HGNC:571)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
AP3S2
(HGNC:571)
obesity disorder
(MONDO_0011122)
Limited
AP2A2
(HGNC:562)
Alzheimer disease
(MONDO_0004975)
Moderate
AP3D1
(HGNC:568)
Hermansky-Pudlak syndrome 10
(MONDO_0014885)
Strong
APBB2
(HGNC:582)
Alzheimer disease
(MONDO_0004975)
Strong
IGL
(HGNC:5853)
classic Hodgkin lymphoma
(MONDO_0009348)
Limited
IGLL1
(HGNC:5870)
agammaglobulinemia
(MONDO_0015977)
Strong
CD101
(HGNC:5949)
type 1 diabetes mellitus
(MONDO_0005147)
Limited
APEH
(HGNC:586)
Crohn disease
(MONDO_0005011)
Strong
IL13RA1
(HGNC:5974)
systemic sclerosis
(MONDO_0005100)
Disputed
APLP1
(HGNC:597)
polycystic lipomembranous osteodysplasia with sclerosing leukoencephaly
(MONDO_0009092)
Limited
IL13RA1
(HGNC:5974)
asthma
(MONDO_0004979)
Limited
IL1RAPL2
(HGNC:5997)
Sotos syndrome
(MONDO_0019349)
Limited
INCENP
(HGNC:6058)
breast cancer
(MONDO_0007254)
Strong
INPP1
(HGNC:6071)
bipolar disorder
(MONDO_0004985)
Strong
ISG20
(HGNC:6130)
presbycusis
(MONDO_0043765)
Strong
ITGB1BP2
(HGNC:6154)
dilated cardiomyopathy
(MONDO_0005021)
Limited
IRF9
(HGNC:6131)
COVID-19
(MONDO_0100096)
Limited
JUNB
(HGNC:6205)
nodular lymphocyte predominant Hodgkin lymphoma
(MONDO_0044778)
Strong
KCNC3
(HGNC:6235)
spinocerebellar ataxia type 13
(MONDO_0011529)
Strong
KCNH1
(HGNC:6250)
Zimmermann-Laband syndrome
(MONDO_0000200)
Strong
KCNH1
(HGNC:6250)
Temple-Baraitser syndrome
(MONDO_0012735)
Strong
KCNMB2
(HGNC:6286)
hippocampal sclerosis of aging
(MONDO_0005544)
Limited
KCNS2
(HGNC:6301)
essential tremor
(MONDO_0003233)
Limited
KLHL3
(HGNC:6354)
pseudohypoaldosteronism type 2
(MONDO_0019162)
Strong
KLK14
(HGNC:6362)
prostate cancer
(MONDO_0008315)
Strong
AQP3
(HGNC:636)
COVID-19
(MONDO_0100096)
Strong
KMO
(HGNC:6381)
schizophrenia
(MONDO_0005090)
Limited
KIFC1
(HGNC:6389)
primary ciliary dyskinesia
(MONDO_0016575)
Disputed
KRT12
(HGNC:6414)
Meesmann corneal dystrophy
(MONDO_0007379)
Definitive
KRT13
(HGNC:6415)
hereditary mucosal leukokeratosis
(MONDO_0015748)
Strong
AQP8
(HGNC:642)
colorectal cancer
(MONDO_0005575)
Limited
KRT2
(HGNC:6439)
superficial epidermolytic ichthyosis
(MONDO_0007813)
Strong
KRT4
(HGNC:6441)
hereditary mucosal leukokeratosis
(MONDO_0015748)
Strong
KRT6B
(HGNC:6444)
pachyonychia congenita
(MONDO_0016471)
Strong
KRT82
(HGNC:6459)
keratoconus
(MONDO_0015486)
Moderate
KRT86
(HGNC:6463)
monilethrix
(MONDO_0008009)
Strong
LAIR2
(HGNC:6478)
pemphigus foliaceus
(MONDO_0019324)
Strong
LARS1
(HGNC:6512)
infantile liver failure syndrome 1
(MONDO_0024568)
Definitive
ARF1
(HGNC:652)
periventricular nodular heterotopia
(MONDO_0020341)
Strong
COG1
(HGNC:6545)
congenital disorder of glycosylation
(MONDO_0015286)
Moderate
COG2
(HGNC:6546)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
LETM1
(HGNC:6556)
Wolf-Hirschhorn syndrome
(MONDO_0008684)
Strong
LFNG
(HGNC:6560)
spondylocostal dysostosis
(MONDO_0000359)
Strong
LGALS4
(HGNC:6565)
colorectal cancer
(MONDO_0005575)
Strong
LIPF
(HGNC:6622)
Wolman disease
(MONDO_0019148)
Strong
LIPF
(HGNC:6622)
cholesteryl ester storage disease
(MONDO_0019149)
Strong
LLGL2
(HGNC:6629)
severe congenital neutropenia
(MONDO_0018542)
Limited
LLGL2
(HGNC:6629)
acute myeloid leukemia
(MONDO_0018874)
Limited
ARFRP1
(HGNC:662)
lung cancer
(MONDO_0008903)
Strong
IRAG2
(HGNC:6690)
lung adenocarcinoma
(MONDO_0005061)
Limited
LY75
(HGNC:6729)
Crohn disease
(MONDO_0005011)
Strong
LY9
(HGNC:6730)
systemic lupus erythematosus
(MONDO_0007915)
Strong
LMOD3
(HGNC:6649)
nemaline myopathy
(MONDO_0018958)
Definitive
MALL
(HGNC:6818)
nephronophthisis
(MONDO_0019005)
Moderate
ARHGDIA
(HGNC:678)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Strong
MAN1B1
(HGNC:6823)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
MAP3K10
(HGNC:6849)
Langerhans cell histiocytosis
(MONDO_0018310)
Limited
ARHGEF6
(HGNC:685)
intellectual disability
(MONDO_0001071)
Strong
MAPK8IP1
(HGNC:6882)
Potocki-Shaffer syndrome
(MONDO_0011022)
Limited
RHOJ
(HGNC:688)
endometriosis
(MONDO_0005133)
Strong
RHOH
(HGNC:686)
epidermodysplasia verruciformis
(MONDO_0009176)
Strong
MARS1
(HGNC:6898)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
MATN3
(HGNC:6909)
multiple epiphyseal dysplasia
(MONDO_0016648)
Strong
MATR3
(HGNC:6912)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
MBD2
(HGNC:6917)
breast cancer
(MONDO_0007254)
Moderate
MCF2
(HGNC:6940)
epilepsy
(MONDO_0005027)
Strong
ARL2
(HGNC:693)
MRCS syndrome
(MONDO_0016979)
Strong
MAPK9
(HGNC:6886)
hemophilia A
(MONDO_0010602)
Strong
MCF2
(HGNC:6940)
nervous system disorder
(MONDO_0005071)
Limited
MCF2
(HGNC:6940)
neuromuscular disease
(MONDO_0019056)
Limited
MELTF
(HGNC:7037)
lung adenocarcinoma
(MONDO_0005061)
Limited
OGA
(HGNC:7056)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
ARPC2
(HGNC:705)
ulcerative colitis
(MONDO_0005101)
Moderate
MGAT2
(HGNC:7045)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
MGST2
(HGNC:7063)
psoriasis
(MONDO_0005083)
Limited
MGST3
(HGNC:7064)
chronic obstructive pulmonary disease
(MONDO_0005002)
Strong
MINPP1
(HGNC:7102)
pontocerebellar hypoplasia
(MONDO_0020135)
Strong
MLANA
(HGNC:7124)
melanoma
(MONDO_0005105)
Strong
MMP19
(HGNC:7165)
interstitial lung disease 2
(MONDO_0800029)
Strong
MNAT1
(HGNC:7181)
colorectal cancer
(MONDO_0005575)
Strong
MPI
(HGNC:7216)
MPI-congenital disorder of glycosylation
(MONDO_0011257)
Strong
MPDU1
(HGNC:7207)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
MNDA
(HGNC:7183)
type 1 diabetes mellitus
(MONDO_0005147)
Strong
MPI
(HGNC:7216)
congenital disorder of glycosylation
(MONDO_0015286)
Strong
MPP3
(HGNC:7221)
X-linked intellectual disability
(MONDO_0100284)
Limited
MT1E
(HGNC:7397)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
SEPTIN9
(HGNC:7323)
amyotrophic neuralgia
(MONDO_0008076)
Strong
MXRA5
(HGNC:7539)
malignant pleural mesothelioma
(MONDO_0005112)
Limited
GET3
(HGNC:752)
prostate cancer
(MONDO_0008315)
Limited
ASPH
(HGNC:757)
facial dysmorphism-lens dislocation-anterior segment abnormalities-spontaneous filtering blebs syndrome
(MONDO_0011106)
Strong
NAB1
(HGNC:7626)
idiopathic inflammatory myopathy
(MONDO_0600023)
Strong
NAB2
(HGNC:7627)
solitary fibrous tumor
(MONDO_0016238)
Strong
MYL4
(HGNC:7585)
atrial fibrillation
(MONDO_0004981)
Strong
MYO1E
(HGNC:7599)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Strong
NCKAP1
(HGNC:7666)
intellectual disability
(MONDO_0001071)
Strong
NDST3
(HGNC:7682)
bipolar disorder
(MONDO_0004985)
Limited
NDST1
(HGNC:7680)
intellectual disability
(MONDO_0001071)
Strong
NDST3
(HGNC:7682)
schizophrenia
(MONDO_0005090)
Limited
NDUFA5
(HGNC:7688)
mucocutaneous lymph node syndrome
(MONDO_0012727)
Strong
NDUFA10
(HGNC:7684)
Leigh syndrome
(MONDO_0009723)
Strong
NDUFA9
(HGNC:7693)
Leigh syndrome
(MONDO_0009723)
Limited
NDUFA8
(HGNC:7692)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFC2
(HGNC:7706)
Leigh syndrome
(MONDO_0009723)
Strong
NDUFS4
(HGNC:7711)
Leigh syndrome
(MONDO_0009723)
Strong
NFIC
(HGNC:7786)
neurofibromatosis type 1
(MONDO_0018975)
Limited
NFE2
(HGNC:7780)
acute myeloid leukemia
(MONDO_0018874)
Moderate
NEK3
(HGNC:7746)
situs inversus
(MONDO_0010029)
Strong
NFYA
(HGNC:7804)
Alzheimer disease
(MONDO_0004975)
Moderate
TONSL
(HGNC:7801)
spondyloepimetaphyseal dysplasia, sponastrime type
(MONDO_0010068)
Strong
NFKBIB
(HGNC:7798)
rheumatoid arthritis
(MONDO_0008383)
Limited
NMU
(HGNC:7859)
anorexia nervosa
(MONDO_0005351)
Limited
NIT1
(HGNC:7828)
EAST syndrome
(MONDO_0013005)
Strong
NNAT
(HGNC:7860)
anorexia nervosa
(MONDO_0005351)
Strong
NKX2-2
(HGNC:7835)
neonatal diabetes mellitus
(MONDO_0016391)
Strong
NOX3
(HGNC:7890)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
NPM2
(HGNC:7930)
premature menopause
(MONDO_0001119)
Strong
NOVA1
(HGNC:7886)
Rett syndrome
(MONDO_0010726)
Limited
ATOH1
(HGNC:797)
intellectual disability
(MONDO_0001071)
Limited
NR4A3
(HGNC:7982)
extraskeletal myxoid chondrosarcoma
(MONDO_0012825)
Strong
NR6A1
(HGNC:7985)
microphthalmia, isolated, with coloboma
(MONDO_0000170)
Strong
NRBP1
(HGNC:7993)
steroid-resistant nephrotic syndrome
(MONDO_0044765)
Limited
NRDC
(HGNC:7995)
alcohol dependence
(MONDO_0007079)
Strong
NUDT2
(HGNC:8049)
intellectual disability
(MONDO_0001071)
Strong
OCM
(HGNC:8105)
autism
(MONDO_0005260)
Limited
ATP2A3
(HGNC:813)
benign essential blepharospasm
(MONDO_0011728)
Strong
OCLN
(HGNC:8104)
pseudo-TORCH syndrome
(MONDO_0009626)
Strong
OPHN1
(HGNC:8148)
X-linked intellectual disability
(MONDO_0100284)
Strong
ATP5PB
(HGNC:840)
acute myeloid leukemia
(MONDO_0018874)
Moderate
OPTC
(HGNC:8158)
OPTN-related open angle glaucoma
(MONDO_0100553)
Limited
ACAA1
(HGNC:82)
asthma
(MONDO_0004979)
Moderate
OSM
(HGNC:8506)
cardiovascular disorder
(MONDO_0004995)
Limited
ATP5PO
(HGNC:850)
mitochondrial disease
(MONDO_0044970)
Strong
P2RY11
(HGNC:8540)
narcolepsy
(MONDO_0021107)
Strong
OVOL1
(HGNC:8525)
atopic eczema
(MONDO_0004980)
Strong
BLOC1S6
(HGNC:8549)
Hermansky-Pudlak syndrome
(MONDO_0019312)
Strong
PACSIN2
(HGNC:8571)
acute lymphoblastic leukemia
(MONDO_0004967)
Limited
SLC45A3
(HGNC:8642)
prostate cancer
(MONDO_0008315)
Limited
ATP6V1B2
(HGNC:854)
DOORS syndrome
(MONDO_0009079)
Strong
PANX2
(HGNC:8600)
schizophrenia
(MONDO_0005090)
Limited
PCOLCE2
(HGNC:8739)
colorectal cancer
(MONDO_0005575)
Limited
PDE1B
(HGNC:8775)
schizophrenia
(MONDO_0005090)
Moderate
PDCD2
(HGNC:8762)
type 1 diabetes mellitus
(MONDO_0005147)
Disputed
ACAD8
(HGNC:87)
isobutyryl-CoA dehydrogenase deficiency
(MONDO_0012648)
Strong
PDK4
(HGNC:8812)
abdominal obesity-metabolic syndrome
(MONDO_0000816)
Limited
PDK4
(HGNC:8812)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
PEX12
(HGNC:8854)
peroxisome biogenesis disorder
(MONDO_0019234)
Strong
PEX12
(HGNC:8854)
Zellweger spectrum disorders
(MONDO_0019609)
Strong
ATRN
(HGNC:885)
restless legs syndrome
(MONDO_0005391)
Limited
PEX13
(HGNC:8855)
peroxisome biogenesis disorder
(MONDO_0019234)
Strong
PEX3
(HGNC:8858)
peroxisome biogenesis disorder
(MONDO_0019234)
Strong
PGAM2
(HGNC:8889)
glycogen storage disease due to phosphoglycerate mutase deficiency
(MONDO_0009865)
Strong
INPP5J
(HGNC:8956)
colon carcinoma
(MONDO_0002032)
Limited
SERPINA4
(HGNC:8948)
acute kidney failure
(MONDO_0002492)
Limited
INPP5J
(HGNC:8956)
uterine corpus leiomyoma
(MONDO_0007886)
Limited
INPP5J
(HGNC:8956)
breast cancer
(MONDO_0007254)
Limited
INPP5J
(HGNC:8956)
prostate cancer
(MONDO_0008315)
Limited
PIGL
(HGNC:8966)
CHIME syndrome
(MONDO_0010221)
Strong
PI4KB
(HGNC:8984)
EAST syndrome
(MONDO_0013005)
Limited
PKNOX1
(HGNC:9022)
plasma cell myeloma
(MONDO_0009693)
Moderate
PKP1
(HGNC:9023)
epidermolysis bullosa simplex due to plakophilin deficiency
(MONDO_0011472)
Strong
PKP4
(HGNC:9026)
sick sinus syndrome
(MONDO_0001823)
Limited
PIGC
(HGNC:8960)
intellectual disability
(MONDO_0001071)
Strong
PLA2G10
(HGNC:9029)
schizophrenia
(MONDO_0005090)
Disputed
PLCD3
(HGNC:9061)
hypertensive disorder
(MONDO_0005044)
Limited
PLA2G5
(HGNC:9038)
Stargardt disease
(MONDO_0019353)
Limited
PLXNB2
(HGNC:9104)
Phelan-McDermid syndrome
(MONDO_0011652)
Limited
PNKD
(HGNC:9153)
paroxysmal nonkinesigenic dyskinesia
(MONDO_0700088)
Strong
PLCD3
(HGNC:9061)
cardiovascular disorder
(MONDO_0004995)
Moderate
EXOSC9
(HGNC:9137)
pontocerebellar hypoplasia
(MONDO_0020135)
Strong
POLR2C
(HGNC:9189)
premature menopause
(MONDO_0001119)
Strong
PPIL1
(HGNC:9260)
pontocerebellar hypoplasia
(MONDO_0020135)
Strong
PPOX
(HGNC:9280)
variegate porphyria
(MONDO_0008297)
Strong
PTPA
(HGNC:9308)
Parkinson disease
(MONDO_0005180)
Limited
PPP1R3C
(HGNC:9293)
Lafora disease
(MONDO_0009697)
Strong
PPP2R5B
(HGNC:9310)
multiple endocrine neoplasia type 1
(MONDO_0007540)
Disputed
PPY
(HGNC:9327)
morbid obesity
(MONDO_0005139)
Disputed
PPT2
(HGNC:9326)
chronic obstructive pulmonary disease
(MONDO_0005002)
Strong
BAAT
(HGNC:932)
intrahepatic cholestasis
(MONDO_0019072)
Moderate
PKN2
(HGNC:9406)
type 2 diabetes mellitus
(MONDO_0005148)
Disputed
PRKAB2
(HGNC:9379)
type 2 diabetes mellitus
(MONDO_0005148)
Refuted
PQBP1
(HGNC:9330)
Renpenning syndrome
(MONDO_0010653)
Strong
BAIAP2
(HGNC:947)
breast cancer
(MONDO_0007254)
Limited
BAG5
(HGNC:941)
dilated cardiomyopathy
(MONDO_0005021)
Strong
TMPRSS15
(HGNC:9490)
congenital enteropathy due to enteropeptidase deficiency
(MONDO_0009173)
Strong
BCR
(HGNC:1014)
acute myeloid leukemia
(MONDO_0018874)
Limited
BCR
(HGNC:1014)
acute lymphoblastic leukemia
(MONDO_0004967)
Strong
RHO
(HGNC:10012)
retinitis pigmentosa
(MONDO_0019200)
Definitive
ROR2
(HGNC:10257)
Robinow syndrome
(MONDO_0019978)
Definitive
RPS6KA3
(HGNC:10432)
Coffin-Lowry syndrome
(MONDO_0010561)
Definitive
RPS19
(HGNC:10402)
Diamond-Blackfan anemia
(MONDO_0015253)
Definitive
RPGR
(HGNC:10295)
primary ciliary dyskinesia
(MONDO_0016575)
Moderate
RPGR
(HGNC:10295)
retinitis pigmentosa
(MONDO_0019200)
Definitive
RPE65
(HGNC:10294)
Leber congenital amaurosis
(MONDO_0018998)
Definitive
SACS
(HGNC:10519)
Charlevoix-Saguenay spastic ataxia
(MONDO_0010041)
Definitive
SCNN1A
(HGNC:10599)
Liddle syndrome
(MONDO_0008323)
Limited
RUNX2
(HGNC:10472)
cleidocranial dysplasia 1
(MONDO_0007340)
Definitive
SCNN1A
(HGNC:10599)
pseudohypoaldosteronism type 1
(MONDO_0019161)
Definitive
SALL1
(HGNC:10524)
Townes-Brocks syndrome
(MONDO_0007142)
Definitive
SCNN1G
(HGNC:10602)
Liddle syndrome
(MONDO_0008323)
Definitive
SCNN1B
(HGNC:10600)
Liddle syndrome
(MONDO_0008323)
Definitive
BCR
(HGNC:1014)
chronic myelogenous leukemia, BCR-ABL1 positive
(MONDO_0011996)
Definitive
SGCA
(HGNC:10805)
autosomal recessive limb-girdle muscular dystrophy type 2D
(MONDO_0011968)
Definitive
RS1
(HGNC:10457)
X-linked retinoschisis
(MONDO_0010725)
Definitive
SGCE
(HGNC:10808)
myoclonic dystonia 11
(MONDO_0008044)
Definitive
SGCB
(HGNC:10806)
autosomal recessive limb-girdle muscular dystrophy type 2E
(MONDO_0011423)
Definitive
SGSH
(HGNC:10818)
mucopolysaccharidosis type 3A
(MONDO_0009655)
Definitive
SGCG
(HGNC:10809)
autosomal recessive limb-girdle muscular dystrophy type 2C
(MONDO_0009677)
Strong
SGCG
(HGNC:10809)
limb-girdle muscular dystrophy
(MONDO_0016971)
Strong
SHOX
(HGNC:10853)
Leri-Weill dyschondrosteosis
(MONDO_0007481)
Definitive
SGSH
(HGNC:10818)
mucopolysaccharidosis type 3
(MONDO_0018937)
Definitive
FOXL2
(HGNC:1092)
premature menopause
(MONDO_0001119)
Moderate
FOXL2
(HGNC:1092)
granulosa cell tumor
(MONDO_0006036)
Definitive
FOXL2
(HGNC:1092)
blepharophimosis, ptosis, and epicanthus inversus syndrome
(MONDO_0007201)
Definitive
SLC17A5
(HGNC:10933)
Salla disease
(MONDO_0011449)
Definitive
SLC19A2
(HGNC:10938)
thiamine-responsive megaloblastic anemia syndrome
(MONDO_0009575)
Definitive
SLC20A2
(HGNC:10947)
basal ganglia calcification, idiopathic, 1
(MONDO_0024538)
Definitive
SLCO2A1
(HGNC:10955)
primary hypertrophic osteoarthropathy
(MONDO_0016620)
Definitive
SLC22A5
(HGNC:10969)
systemic primary carnitine deficiency disease
(MONDO_0008919)
Definitive
SLC26A2
(HGNC:10994)
multiple epiphyseal dysplasia
(MONDO_0016648)
Strong
SH2D1A
(HGNC:10820)
X-linked lymphoproliferative syndrome
(MONDO_0010627)
Definitive
SLC34A1
(HGNC:11019)
hypercalcemia, infantile
(MONDO_0000212)
Definitive
SHOX
(HGNC:10853)
Turner syndrome
(MONDO_0019499)
Definitive
SHOX
(HGNC:10853)
Langer mesomelic dysplasia
(MONDO_0009588)
Strong
SLC40A1
(HGNC:10909)
hemochromatosis type 1
(MONDO_0021001)
Limited
SLC5A5
(HGNC:11040)
congenital hypothyroidism
(MONDO_0018612)
Strong
SLC40A1
(HGNC:10909)
hereditary hemochromatosis
(MONDO_0006507)
Definitive
SLC6A1
(HGNC:11042)
myoclonic-astatic epilepsy
(MONDO_0016025)
Strong
SLC6A8
(HGNC:11055)
creatine transporter deficiency
(MONDO_0010305)
Definitive
SLC12A1
(HGNC:10910)
Bartter syndrome
(MONDO_0015231)
Definitive
SLC16A2
(HGNC:10923)
Allan-Herndon-Dudley syndrome
(MONDO_0010354)
Definitive
SHH
(HGNC:10848)
holoprosencephaly
(MONDO_0016296)
Definitive
SLC26A2
(HGNC:10994)
diastrophic dysplasia
(MONDO_0009107)
Definitive
SMARCAL1
(HGNC:11102)
Schimke immuno-osseous dysplasia
(MONDO_0009458)
Definitive
SMARCA2
(HGNC:11098)
intellectual disability-sparse hair-brachydactyly syndrome
(MONDO_0011053)
Definitive
SLC7A7
(HGNC:11065)
lysinuric protein intolerance
(MONDO_0009109)
Definitive
SMC1A
(HGNC:11111)
Cornelia de Lange syndrome
(MONDO_0016033)
Definitive
SLC5A2
(HGNC:11037)
familial renal glucosuria
(MONDO_0009297)
Strong
KDM5C
(HGNC:11114)
X-linked intellectual disability
(MONDO_0100284)
Definitive
SLC3A1
(HGNC:11025)
cystinuria
(MONDO_0009067)
Definitive
SLC7A9
(HGNC:11067)
cystinuria
(MONDO_0009067)
Definitive
SMN1
(HGNC:11117)
spinal muscular atrophy
(MONDO_0001516)
Definitive
SMN1
(HGNC:11117)
spinal muscular atrophy, type 1
(MONDO_0009669)
Definitive
SLC12A1
(HGNC:10910)
Bartter disease type 1
(MONDO_0100344)
Definitive
SON
(HGNC:11183)
ZTTK syndrome
(MONDO_0014936)
Definitive
SLC5A5
(HGNC:11040)
hypothyroidism due to iodide transport defect
(MONDO_0043103)
Definitive
SMN2
(HGNC:11118)
spinal muscular atrophy
(MONDO_0001516)
Strong
SOX5
(HGNC:11201)
Lamb-Shaffer syndrome
(MONDO_0014778)
Definitive
SLC9A6
(HGNC:11079)
Christianson syndrome
(MONDO_0010278)
Definitive
SLC34A2
(HGNC:11020)
pulmonary alveolar microlithiasis
(MONDO_0009928)
Strong
SPG11
(HGNC:11226)
hereditary spastic paraplegia 11
(MONDO_0011445)
Definitive
SORL1
(HGNC:11185)
Alzheimer disease
(MONDO_0004975)
Strong
SNRPN
(HGNC:11164)
Prader-Willi syndrome
(MONDO_0008300)
Definitive
SLC40A1
(HGNC:10909)
hemochromatosis type 4
(MONDO_0011631)
Definitive
SPG11
(HGNC:11226)
hereditary spastic paraplegia
(MONDO_0019064)
Definitive
ATL1
(HGNC:11231)
hereditary spastic paraplegia 3A
(MONDO_0008437)
Definitive
BTD
(HGNC:1122)
biotinidase deficiency
(MONDO_0009665)
Definitive
SPOP
(HGNC:11254)
prostate cancer
(MONDO_0008315)
Limited
ATL1
(HGNC:11231)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
SPAST
(HGNC:11233)
hereditary spastic paraplegia 4
(MONDO_0008438)
Definitive
STIM1
(HGNC:11386)
Stormorken syndrome
(MONDO_0008497)
Strong
CDKL5
(HGNC:11411)
developmental and epileptic encephalopathy, 2
(MONDO_0010396)
Definitive
CDKL5
(HGNC:11411)
Rett syndrome
(MONDO_0010726)
Definitive
SPAST
(HGNC:11233)
hereditary spastic paraplegia
(MONDO_0019064)
Definitive
SPTB
(HGNC:11274)
hereditary elliptocytosis
(MONDO_0017319)
Definitive
STX11
(HGNC:11429)
hereditary hemophagocytic lymphohistiocytosis
(MONDO_0015541)
Definitive
STXBP2
(HGNC:11445)
hereditary hemophagocytic lymphohistiocytosis
(MONDO_0015541)
Definitive
SYNGAP1
(HGNC:11497)
autism spectrum disorder
(MONDO_0005258)
Definitive
TACSTD2
(HGNC:11530)
gelatinous drop-like corneal dystrophy
(MONDO_0008777)
Definitive
TAFAZZIN
(HGNC:11577)
Barth syndrome
(MONDO_0010543)
Definitive
SPR
(HGNC:11257)
dopa-responsive dystonia due to sepiapterin reductase deficiency
(MONDO_0012994)
Definitive
SPTA1
(HGNC:11272)
pyropoikilocytosis, hereditary
(MONDO_0009948)
Strong
SUOX
(HGNC:11460)
isolated sulfite oxidase deficiency
(MONDO_0010089)
Definitive
TBK1
(HGNC:11584)
amyotrophic lateral sclerosis
(MONDO_0004976)
Definitive
SPTA1
(HGNC:11272)
hereditary elliptocytosis
(MONDO_0017319)
Definitive
TBK1
(HGNC:11584)
frontotemporal dementia
(MONDO_0017276)
Definitive
TBX3
(HGNC:11602)
ulnar-mammary syndrome
(MONDO_0008411)
Definitive
TCIRG1
(HGNC:11647)
osteopetrosis
(MONDO_0017198)
Strong
TCN2
(HGNC:11653)
transcobalamin II deficiency
(MONDO_0010149)
Definitive
TCIRG1
(HGNC:11647)
autosomal recessive osteopetrosis
(MONDO_0019026)
Definitive
TCOF1
(HGNC:11654)
Treacher-Collins syndrome
(MONDO_0002457)
Definitive
TFAP2A
(HGNC:11742)
branchiooculofacial syndrome
(MONDO_0007235)
Definitive
TFR2
(HGNC:11762)
hereditary hemochromatosis
(MONDO_0006507)
Strong
TGFB2
(HGNC:11768)
Loeys-Dietz syndrome
(MONDO_0018954)
Strong
TFE3
(HGNC:11752)
neoplasm with perivascular epithelioid cell differentiation
(MONDO_0006359)
Strong
TGM1
(HGNC:11777)
autosomal recessive congenital ichthyosis
(MONDO_0017265)
Definitive
TGM1
(HGNC:11777)
lamellar ichthyosis
(MONDO_0017778)
Definitive
THBD
(HGNC:11784)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Definitive
THRA
(HGNC:11796)
thyroid hormone resistance syndrome
(MONDO_0001328)
Strong
TINF2
(HGNC:11824)
dyskeratosis congenita
(MONDO_0015780)
Definitive
TK2
(HGNC:11831)
mitochondrial DNA depletion syndrome
(MONDO_0018158)
Definitive
TBX1
(HGNC:11592)
DiGeorge syndrome
(MONDO_0008564)
Strong
CD40LG
(HGNC:11935)
hyper-IgM syndrome
(MONDO_0003947)
Definitive
TNNI3
(HGNC:11947)
hypertrophic cardiomyopathy
(MONDO_0005045)
Definitive
TNNI3
(HGNC:11947)
restrictive cardiomyopathy
(MONDO_0005201)
Strong
STAG2
(HGNC:11355)
acute myeloid leukemia
(MONDO_0018874)
Strong
SPTA1
(HGNC:11272)
hereditary spherocytosis
(MONDO_0019350)
Strong
SPTBN2
(HGNC:11276)
spinocerebellar ataxia type 5
(MONDO_0010848)
Strong
SPTB
(HGNC:11274)
hereditary spherocytosis
(MONDO_0019350)
Strong
SURF1
(HGNC:11474)
Leigh syndrome
(MONDO_0009723)
Definitive
SPTLC1
(HGNC:11277)
hereditary sensory and autonomic neuropathy type 1
(MONDO_0018213)
Definitive
STIM1
(HGNC:11386)
tubular aggregate myopathy
(MONDO_0008051)
Definitive
TPM1
(HGNC:12010)
dilated cardiomyopathy
(MONDO_0005021)
Strong
TPM1
(HGNC:12010)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
TPM3
(HGNC:12012)
cap myopathy
(MONDO_0015753)
Strong
SERPING1
(HGNC:1228)
hereditary angioedema
(MONDO_0019623)
Definitive
TPM3
(HGNC:12012)
nemaline myopathy
(MONDO_0018958)
Strong
TRPC6
(HGNC:12338)
focal segmental glomerulosclerosis
(MONDO_0100313)
Strong
TRPS1
(HGNC:12340)
trichorhinophalangeal syndrome type I
(MONDO_0008596)
Definitive
TRPS1
(HGNC:12340)
trichorhinophalangeal syndrome
(MONDO_0017951)
Definitive
TTPA
(HGNC:12404)
familial isolated deficiency of vitamin E
(MONDO_0010188)
Definitive
TWIST1
(HGNC:12428)
Saethre-Chotzen syndrome
(MONDO_0007042)
Definitive
TWIST1
(HGNC:12428)
craniosynostosis
(MONDO_0015469)
Definitive
UBE3A
(HGNC:12496)
Angelman syndrome
(MONDO_0007113)
Definitive
UBA1
(HGNC:12469)
VEXAS syndrome
(MONDO_0026777)
Strong
UROD
(HGNC:12591)
porphyria cutanea tarda
(MONDO_0015104)
Definitive
TNXB
(HGNC:11976)
Ehlers-Danlos syndrome
(MONDO_0020066)
Definitive
TIMP3
(HGNC:11822)
Sorsby fundus dystrophy
(MONDO_0007640)
Strong
UROD
(HGNC:12591)
hepatoerythropoietic porphyria
(MONDO_0019799)
Definitive
CD40LG
(HGNC:11935)
hyper-IgM syndrome type 1
(MONDO_0010626)
Definitive
UROS
(HGNC:12592)
cutaneous porphyria
(MONDO_0009902)
Definitive
TNNT1
(HGNC:11948)
nemaline myopathy
(MONDO_0018958)
Strong
VPS33B
(HGNC:12712)
arthrogryposis-renal dysfunction-cholestasis syndrome
(MONDO_0017123)
Definitive
USP8
(HGNC:12631)
Cushing disease due to pituitary adenoma
(MONDO_0009050)
Strong
NSD2
(HGNC:12766)
Wolf-Hirschhorn syndrome
(MONDO_0008684)
Definitive
CCN6
(HGNC:12771)
progressive pseudorheumatoid arthropathy of childhood
(MONDO_0008827)
Definitive
XK
(HGNC:12811)
McLeod neuroacanthocytosis syndrome
(MONDO_0018945)
Definitive
XDH
(HGNC:12805)
xanthinuria type I
(MONDO_0010209)
Strong
ZMPSTE24
(HGNC:12877)
mandibuloacral dysplasia
(MONDO_0016584)
Strong
ZMPSTE24
(HGNC:12877)
restrictive dermopathy
(MONDO_0031213)
Definitive
WNT1
(HGNC:12774)
osteogenesis imperfecta
(MONDO_0019019)
Definitive
KAT6A
(HGNC:13013)
autosomal dominant intellectual disability-craniofacial anomalies-cardiac defects syndrome
(MONDO_0014558)
Definitive
ACTA2
(HGNC:130)
thoracic aortic aneurysm
(MONDO_0005396)
Definitive
ACTA2
(HGNC:130)
multisystemic smooth muscle dysfunction syndrome
(MONDO_0013452)
Definitive
EML4
(HGNC:1316)
non-small cell lung carcinoma
(MONDO_0005233)
Definitive
EML4
(HGNC:1316)
lung adenocarcinoma
(MONDO_0005061)
Definitive
EML4
(HGNC:1316)
lung cancer
(MONDO_0008903)
Strong
HDAC8
(HGNC:13315)
Cornelia de Lange syndrome
(MONDO_0016033)
Strong
ATP2C1
(HGNC:13211)
Hailey-Hailey disease
(MONDO_0008218)
Definitive
MCOLN1
(HGNC:13356)
mucolipidosis type IV
(MONDO_0009653)
Definitive
SAMD9
(HGNC:1348)
MIRAGE syndrome
(MONDO_0014888)
Definitive
ACTB
(HGNC:132)
Baraitser-Winter cerebrofrontofacial syndrome
(MONDO_0017579)
Definitive
NSDHL
(HGNC:13398)
CHILD syndrome
(MONDO_0010621)
Definitive
SAMD9L
(HGNC:1349)
ataxia-pancytopenia syndrome
(MONDO_0008038)
Strong
FBXO7
(HGNC:13586)
parkinsonian-pyramidal syndrome
(MONDO_0009830)
Strong
VPS35
(HGNC:13487)
Parkinson disease
(MONDO_0005180)
Strong
AAAS
(HGNC:13666)
triple-A syndrome
(MONDO_0009279)
Definitive
FBXO7
(HGNC:13586)
Parkinson disease
(MONDO_0005180)
Strong
ABCG5
(HGNC:13886)
familial hypercholesterolemia
(MONDO_0005439)
Limited
FBXL4
(HGNC:13601)
mitochondrial DNA depletion syndrome
(MONDO_0018158)
Definitive
CACNA1D
(HGNC:1391)
primary aldosteronism
(MONDO_0001422)
Strong
ABCG8
(HGNC:13887)
sitosterolemia
(MONDO_0008863)
Definitive
CA2
(HGNC:1373)
autosomal recessive osteopetrosis 3
(MONDO_0009818)
Definitive
ABCG5
(HGNC:13886)
sitosterolemia
(MONDO_0008863)
Definitive
CACNA1H
(HGNC:1395)
primary aldosteronism
(MONDO_0001422)
Strong
SOST
(HGNC:13771)
sclerosteosis
(MONDO_0017838)
Strong
SLC25A20
(HGNC:1421)
carnitine-acylcarnitine translocase deficiency
(MONDO_0008918)
Definitive
SHANK3
(HGNC:14294)
Phelan-McDermid syndrome
(MONDO_0011652)
Definitive
EDARADD
(HGNC:14341)
ectodermal dysplasia syndrome
(MONDO_0019287)
Strong
ACTC1
(HGNC:143)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
CALM1
(HGNC:1442)
long QT syndrome
(MONDO_0002442)
Definitive
SHANK3
(HGNC:14294)
autism spectrum disorder
(MONDO_0005258)
Definitive
NPC2
(HGNC:14537)
Niemann-Pick disease type C
(MONDO_0018982)
Definitive
EDARADD
(HGNC:14341)
hypohidrotic ectodermal dysplasia
(MONDO_0016535)
Moderate
PINK1
(HGNC:14581)
Parkinson disease
(MONDO_0005180)
Definitive
ABCA12
(HGNC:14637)
autosomal recessive congenital ichthyosis
(MONDO_0017265)
Definitive
ABCA12
(HGNC:14637)
autosomal recessive congenital ichthyosis 4B
(MONDO_0009443)
Definitive
NSD1
(HGNC:14234)
Sotos syndrome
(MONDO_0019349)
Definitive
CACNA1F
(HGNC:1393)
congenital stationary night blindness
(MONDO_0016293)
Definitive
RNF213
(HGNC:14539)
Moyamoya disease
(MONDO_0016820)
Definitive
ACTG2
(HGNC:145)
megacystis-microcolon-intestinal hypoperistalsis syndrome
(MONDO_0025986)
Strong
ACTG1
(HGNC:144)
Baraitser-Winter cerebrofrontofacial syndrome
(MONDO_0017579)
Definitive
ABCA12
(HGNC:14637)
lamellar ichthyosis
(MONDO_0017778)
Definitive
ABCA12
(HGNC:14637)
congenital non-bullous ichthyosiform erythroderma
(MONDO_0019306)
Strong
CAPN3
(HGNC:1480)
autosomal recessive limb-girdle muscular dystrophy type 2A
(MONDO_0009675)
Definitive
ZEB2
(HGNC:14881)
Mowat-Wilson syndrome
(MONDO_0009341)
Definitive
CAPN3
(HGNC:1480)
limb-girdle muscular dystrophy
(MONDO_0016971)
Definitive
CBFB
(HGNC:1539)
acute myeloid leukemia
(MONDO_0018874)
Definitive
RUNX1T1
(HGNC:1535)
acute myeloid leukemia
(MONDO_0018874)
Definitive
CASQ2
(HGNC:1513)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Definitive
PRPF31
(HGNC:15446)
retinitis pigmentosa
(MONDO_0019200)
Strong
SHOC2
(HGNC:15454)
Noonan syndrome
(MONDO_0018997)
Definitive
SHOC2
(HGNC:15454)
RASopathy
(MONDO_0021060)
Definitive
SPINK5
(HGNC:15464)
Netherton syndrome
(MONDO_0009735)
Definitive
MBTPS2
(HGNC:15455)
IFAP syndrome
(MONDO_0100212)
Strong
IL36RN
(HGNC:15561)
psoriasis 14, pustular
(MONDO_0013626)
Definitive
IL36RN
(HGNC:15561)
generalized pustular psoriasis
(MONDO_0100491)
Definitive
KRIT1
(HGNC:1573)
cerebral cavernous malformation
(MONDO_0000820)
Definitive
ADNP
(HGNC:15766)
ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder
(MONDO_0014379)
Definitive
ABHD12
(HGNC:15868)
PHARC syndrome
(MONDO_0012984)
Definitive
FERMT1
(HGNC:15889)
Kindler syndrome
(MONDO_0008260)
Definitive
PANK2
(HGNC:15894)
pantothenate kinase-associated neurodegeneration
(MONDO_0009319)
Definitive
PANK2
(HGNC:15894)
neurodegeneration with brain iron accumulation
(MONDO_0018307)
Definitive
SAMHD1
(HGNC:15925)
Aicardi-Goutieres syndrome
(MONDO_0018866)
Definitive
RP1L1
(HGNC:15946)
occult macular dystrophy
(MONDO_0013316)
Strong
GDAP1
(HGNC:15968)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
APTX
(HGNC:15984)
ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia
(MONDO_0008842)
Definitive
PCNT
(HGNC:16068)
microcephalic osteodysplastic primordial dwarfism type II
(MONDO_0008872)
Definitive
SLC52A3
(HGNC:16187)
riboflavin transporter deficiency
(MONDO_0008891)
Definitive
SLC19A3
(HGNC:16266)
biotin-responsive basal ganglia disease
(MONDO_0011841)
Definitive
PNPLA6
(HGNC:16268)
ataxia-hypogonadism-choroidal dystrophy syndrome
(MONDO_0008980)
Strong
TRIM32
(HGNC:16380)
autosomal recessive limb-girdle muscular dystrophy type 2H
(MONDO_0009683)
Strong
PARK7
(HGNC:16369)
Parkinson disease
(MONDO_0005180)
Strong
CARD9
(HGNC:16391)
phaeohyphomycosis
(MONDO_0001867)
Strong
CARD14
(HGNC:16446)
pityriasis rubra pilaris
(MONDO_0100017)
Strong
CARD9
(HGNC:16391)
deep seated dermatophytosis
(MONDO_0021660)
Definitive
CARD9
(HGNC:16391)
predisposition to invasive fungal disease due to CARD9 deficiency
(MONDO_0008905)
Definitive
SUFU
(HGNC:16466)
nevoid basal cell carcinoma syndrome
(MONDO_0007187)
Definitive
TMPRSS6
(HGNC:16517)
IRIDA syndrome
(MONDO_0008788)
Definitive
IFITM5
(HGNC:16644)
osteogenesis imperfecta
(MONDO_0019019)
Definitive
SLC45A2
(HGNC:16472)
oculocutaneous albinism
(MONDO_0018910)
Definitive
RAB39B
(HGNC:16499)
Parkinson disease
(MONDO_0005180)
Moderate
UBR1
(HGNC:16808)
Johanson-Blizzard syndrome
(MONDO_0009479)
Definitive
HCN4
(HGNC:16882)
sinoatrial node disorder
(MONDO_0000469)
Strong
HAX1
(HGNC:16915)
Kostmann syndrome
(MONDO_0012548)
Definitive
SRCAP
(HGNC:16974)
Floating-Harbor syndrome
(MONDO_0007621)
Definitive
CD79B
(HGNC:1699)
diffuse large B-cell lymphoma
(MONDO_0018905)
Strong
HAX1
(HGNC:16915)
severe congenital neutropenia
(MONDO_0018542)
Definitive
CFHR3
(HGNC:16980)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Strong
MLC1
(HGNC:17082)
megalencephalic leukoencephalopathy with subcortical cysts
(MONDO_0011391)
Definitive
RAB3GAP1
(HGNC:17063)
Warburg micro syndrome
(MONDO_0016649)
Strong
SLC39A4
(HGNC:17129)
acrodermatitis enteropathica
(MONDO_0008713)
Definitive
ALPK3
(HGNC:17574)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
ACVR1
(HGNC:171)
fibrodysplasia ossificans progressiva
(MONDO_0007606)
Definitive
NGLY1
(HGNC:17646)
congenital disorder of deglycosylation
(MONDO_0031376)
Definitive
KAT6B
(HGNC:17582)
blepharophimosis - intellectual disability syndrome, SBBYS type
(MONDO_0011365)
Definitive
ACVRL1
(HGNC:175)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
TREM2
(HGNC:17761)
Alzheimer disease
(MONDO_0004975)
Strong
TREM2
(HGNC:17761)
polycystic lipomembranous osteodysplasia with sclerosing leukoencephaly
(MONDO_0009092)
Definitive
ACVRL1
(HGNC:175)
hereditary hemorrhagic telangiectasia
(MONDO_0019180)
Definitive
PORCN
(HGNC:17652)
focal dermal hypoplasia
(MONDO_0010592)
Definitive
CDKN1C
(HGNC:1786)
IMAGe syndrome
(MONDO_0013873)
Strong
CDKN1C
(HGNC:1786)
Beckwith-Wiedemann syndrome
(MONDO_0007534)
Definitive
CDH3
(HGNC:1762)
congenital hypotrichosis with juvenile macular dystrophy
(MONDO_0011107)
Definitive
EXOSC3
(HGNC:17944)
pontocerebellar hypoplasia type 1B
(MONDO_0013853)
Strong
KAT6B
(HGNC:17582)
genitopatellar syndrome
(MONDO_0011640)
Definitive
TREM2
(HGNC:17761)
frontotemporal dementia
(MONDO_0017276)
Moderate
IRAK4
(HGNC:17967)
immunodeficiency 67
(MONDO_0011888)
Strong
TRPM6
(HGNC:17995)
intestinal hypomagnesemia 1
(MONDO_0011176)
Definitive
SLC22A12
(HGNC:17989)
hypouricemia, renal 1
(MONDO_0020728)
Strong
NAGS
(HGNC:17996)
urea cycle disorder
(MONDO_0004739)
Definitive
NAGS
(HGNC:17996)
hyperammonemia due to N-acetylglutamate synthase deficiency
(MONDO_0009377)
Definitive
CDSN
(HGNC:1802)
peeling skin syndrome 1
(MONDO_0024548)
Moderate
MFRP
(HGNC:18121)
retinitis pigmentosa
(MONDO_0019200)
Strong
TNFRSF13B
(HGNC:18153)
common variable immunodeficiency
(MONDO_0015517)
Strong
FKBP10
(HGNC:18169)
Bruck syndrome
(MONDO_0017195)
Strong
FKBP10
(HGNC:18169)
osteogenesis imperfecta
(MONDO_0019019)
Strong
ADA2
(HGNC:1839)
vasculitis due to ADA2 deficiency
(MONDO_0014306)
Definitive
ADA2
(HGNC:1839)
polyarteritis nodosa
(MONDO_0019170)
Strong
ADA2
(HGNC:1839)
deficiency of adenosine deaminase 2
(MONDO_0100317)
Strong
DEPDC5
(HGNC:18423)
focal epilepsy
(MONDO_0005384)
Strong
LDLRAP1
(HGNC:18640)
hypercholesterolemia, familial, 4
(MONDO_0011374)
Definitive
DEPDC5
(HGNC:18423)
familial focal epilepsy with variable foci
(MONDO_0020310)
Definitive
DDX41
(HGNC:18674)
acute myeloid leukemia
(MONDO_0018874)
Definitive
ADA
(HGNC:186)
severe combined immunodeficiency
(MONDO_0015974)
Definitive
ADA
(HGNC:186)
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-negative, due to adenosine deaminase deficiency
(MONDO_0007064)
Definitive
NAA10
(HGNC:18704)
Ogden syndrome
(MONDO_0010457)
Definitive
KCNT1
(HGNC:18865)
epilepsy of infancy with migrating focal seizures
(MONDO_0100025)
Strong
ASPM
(HGNC:19048)
autosomal recessive primary microcephaly
(MONDO_0016660)
Definitive
VPS13A
(HGNC:1908)
chorea-acanthocytosis
(MONDO_0008695)
Strong
NPHP4
(HGNC:19104)
nephronophthisis
(MONDO_0019005)
Definitive
POMGNT1
(HGNC:19139)
muscle-eye-brain disease
(MONDO_0018939)
Definitive
DOCK6
(HGNC:19189)
Adams-Oliver syndrome
(MONDO_0007034)
Definitive
DOCK8
(HGNC:19191)
combined immunodeficiency due to DOCK8 deficiency
(MONDO_0009478)
Definitive
DOCK8
(HGNC:19191)
hyper-IgE syndrome
(MONDO_0018037)
Strong
POGZ
(HGNC:18801)
intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome
(MONDO_0014606)
Strong
CHM
(HGNC:1940)
choroideremia
(MONDO_0010557)
Definitive
CHRNA1
(HGNC:1955)
congenital myasthenic syndrome
(MONDO_0018940)
Strong
CHRNB2
(HGNC:1962)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Strong
CHRNE
(HGNC:1966)
congenital myasthenic syndrome
(MONDO_0018940)
Strong
POMT2
(HGNC:19743)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Strong
EVC2
(HGNC:19747)
Ellis-van Creveld syndrome
(MONDO_0009162)
Strong
GPR143
(HGNC:20145)
X-linked recessive ocular albinism
(MONDO_0021019)
Definitive
CLCN1
(HGNC:2019)
myotonia congenita, autosomal dominant
(MONDO_0008055)
Definitive
CLCN5
(HGNC:2023)
Dent disease type 1
(MONDO_0010225)
Definitive
CLCN2
(HGNC:2020)
leukoencephalopathy with mild cerebellar ataxia and white matter edema
(MONDO_0014292)
Definitive
CLCN5
(HGNC:2023)
Dent disease
(MONDO_0015612)
Definitive
SPRED1
(HGNC:20249)
Legius syndrome
(MONDO_0012669)
Definitive
CLCN7
(HGNC:2025)
autosomal dominant osteopetrosis 2
(MONDO_0008156)
Definitive
CLCN7
(HGNC:2025)
osteopetrosis
(MONDO_0017198)
Definitive
CLCN7
(HGNC:2025)
autosomal recessive osteopetrosis
(MONDO_0019026)
Strong
CLCNKB
(HGNC:2027)
Gitelman syndrome
(MONDO_0009904)
Strong
CLCNKB
(HGNC:2027)
Bartter disease type 3
(MONDO_0011822)
Definitive
CLCNKB
(HGNC:2027)
Bartter syndrome
(MONDO_0015231)
Strong
SLC34A3
(HGNC:20305)
hereditary hypophosphatemic rickets with hypercalciuria
(MONDO_0009431)
Definitive
SUMF1
(HGNC:20376)
mucosulfatidosis
(MONDO_0010088)
Definitive
CLDN16
(HGNC:2037)
renal hypomagnesemia 3
(MONDO_0009550)
Definitive
L2HGDH
(HGNC:20499)
L-2-hydroxyglutaric aciduria
(MONDO_0009370)
Definitive
CLDN19
(HGNC:2040)
renal hypomagnesemia 3
(MONDO_0009550)
Strong
CLN3
(HGNC:2074)
neuronal ceroid lipofuscinosis 3
(MONDO_0008767)
Definitive
CLN3
(HGNC:2074)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Definitive
CLN5
(HGNC:2076)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Strong
TUBB4A
(HGNC:20774)
hypomyelinating leukodystrophy 6
(MONDO_0012905)
Definitive
CLN6
(HGNC:2077)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Definitive
SERAC1
(HGNC:21061)
3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome
(MONDO_0013875)
Definitive
FA2H
(HGNC:21197)
fatty acid hydroxylase-associated neurodegeneration
(MONDO_0017999)
Strong
DYM
(HGNC:21317)
Dyggve-Melchior-Clausen disease
(MONDO_0009130)
Definitive
ANKRD11
(HGNC:21316)
KBG syndrome
(MONDO_0007846)
Definitive
ABHD5
(HGNC:21396)
Dorfman-Chanarin disease
(MONDO_0010155)
Definitive
RARS2
(HGNC:21406)
pontocerebellar hypoplasia type 6
(MONDO_0012683)
Definitive
NHLRC1
(HGNC:21576)
Lafora disease
(MONDO_0009697)
Strong
CUL7
(HGNC:21024)
3-M syndrome
(MONDO_0007477)
Definitive
RFX6
(HGNC:21478)
hypoplastic pancreas-intestinal atresia-hypoplastic gallbalder syndrome
(MONDO_0017400)
Definitive
AHI1
(HGNC:21575)
Joubert syndrome
(MONDO_0018772)
Strong
TSPAN12
(HGNC:21641)
exudative vitreoretinopathy
(MONDO_0019516)
Definitive
CCM2
(HGNC:21708)
cerebral cavernous malformation
(MONDO_0000820)
Strong
BRAT1
(HGNC:21701)
neonatal-onset encephalopathy with rigidity and seizures
(MONDO_0013784)
Definitive
ANTXR2
(HGNC:21732)
hyaline fibromatosis syndrome
(MONDO_0009229)
Strong
ANTXR2
(HGNC:21732)
juvenile hyaline fibromatosis
(MONDO_0016071)
Definitive
ANTXR2
(HGNC:21732)
infantile systemic hyalinosis
(MONDO_0016331)
Definitive
COL10A1
(HGNC:2185)
Schmid metaphyseal chondrodysplasia
(MONDO_0007983)
Definitive
VPS13B
(HGNC:2183)
Cohen syndrome
(MONDO_0008999)
Definitive
COL11A2
(HGNC:2187)
Stickler syndrome
(MONDO_0019354)
Strong
COL18A1
(HGNC:2195)
Knobloch syndrome
(MONDO_0800166)
Definitive
COL5A1
(HGNC:2209)
Ehlers-Danlos syndrome, classic type
(MONDO_0007522)
Strong
COL5A1
(HGNC:2209)
Ehlers-Danlos syndrome
(MONDO_0020066)
Definitive
COL17A1
(HGNC:2194)
generalized junctional epidermolysis bullosa non-Herlitz type
(MONDO_0019307)
Strong
COL17A1
(HGNC:2194)
junctional epidermolysis bullosa
(MONDO_0017612)
Definitive
COL11A2
(HGNC:2187)
otospondylomegaepiphyseal dysplasia
(MONDO_0008975)
Strong
COL4A6
(HGNC:2208)
Alport syndrome
(MONDO_0018965)
Limited
COL6A1
(HGNC:2211)
Ullrich congenital muscular dystrophy
(MONDO_0000355)
Definitive
COL6A2
(HGNC:2212)
Ullrich congenital muscular dystrophy
(MONDO_0000355)
Definitive
COL6A2
(HGNC:2212)
Bethlem myopathy
(MONDO_0008029)
Definitive
FAM20C
(HGNC:22140)
lethal osteosclerotic bone dysplasia
(MONDO_0009821)
Definitive
COL6A3
(HGNC:2213)
Bethlem myopathy
(MONDO_0008029)
Strong
COL6A3
(HGNC:2213)
Ullrich congenital muscular dystrophy
(MONDO_0000355)
Strong
ADAR
(HGNC:225)
dyschromatosis symmetrica hereditaria
(MONDO_0007483)
Definitive
CP
(HGNC:2295)
aceruloplasminemia
(MONDO_0011426)
Definitive
ZRSR2
(HGNC:23019)
myelodysplastic syndrome
(MONDO_0018881)
Strong
GNPTG
(HGNC:23026)
GNPTG-mucolipidosis
(MONDO_0009652)
Strong
SLC29A3
(HGNC:23096)
H syndrome
(MONDO_0011273)
Definitive
UNC13D
(HGNC:23147)
hemophagocytic syndrome
(MONDO_0015540)
Strong
UNC13D
(HGNC:23147)
hereditary hemophagocytic lymphohistiocytosis
(MONDO_0015541)
Definitive
CYP4V2
(HGNC:23198)
Bietti crystalline corneoretinal dystrophy
(MONDO_0008865)
Definitive
KEAP1
(HGNC:23177)
non-small cell lung carcinoma
(MONDO_0005233)
Strong
ZNF469
(HGNC:23216)
brittle cornea syndrome 1
(MONDO_0024543)
Definitive
ALG6
(HGNC:23157)
ALG6-congenital disorder of glycosylation 1C
(MONDO_0011291)
Definitive
COL6A1
(HGNC:2211)
Bethlem myopathy
(MONDO_0008029)
Definitive
COLQ
(HGNC:2226)
congenital myasthenic syndrome
(MONDO_0018940)
Definitive
COMP
(HGNC:2227)
multiple epiphyseal dysplasia
(MONDO_0016648)
Definitive
COMP
(HGNC:2227)
pseudoachondroplasia
(MONDO_0008322)
Definitive
ETHE1
(HGNC:23287)
ethylmalonic encephalopathy
(MONDO_0011229)
Strong
CPT1A
(HGNC:2328)
carnitine palmitoyl transferase 1A deficiency
(MONDO_0009705)
Strong
CPT2
(HGNC:2330)
carnitine palmitoyltransferase II deficiency
(MONDO_0015515)
Strong
GNE
(HGNC:23657)
GNE myopathy
(MONDO_0011603)
Definitive
CPT2
(HGNC:2330)
metabolic myopathy
(MONDO_0020123)
Definitive
INF2
(HGNC:23791)
focal segmental glomerulosclerosis
(MONDO_0100313)
Definitive
CRX
(HGNC:2383)
cone-rod dystrophy
(MONDO_0015993)
Strong
CRX
(HGNC:2383)
Leber congenital amaurosis
(MONDO_0018998)
Strong
WDR62
(HGNC:24502)
autosomal recessive primary microcephaly
(MONDO_0016660)
Definitive
WDR62
(HGNC:24502)
isolated congenital microcephaly
(MONDO_0016056)
Definitive
CHMP2B
(HGNC:24537)
frontotemporal dementia
(MONDO_0017276)
Moderate
CSNK2A1
(HGNC:2457)
Okur-Chung neurodevelopmental syndrome
(MONDO_0014893)
Definitive
VCAN
(HGNC:2464)
Wagner disease
(MONDO_0007740)
Definitive
EHMT1
(HGNC:24650)
Kleefstra syndrome
(MONDO_0012455)
Definitive
FLVCR1
(HGNC:24682)
posterior column ataxia-retinitis pigmentosa syndrome
(MONDO_0012177)
Strong
CSTB
(HGNC:2482)
Unverricht-Lundborg syndrome
(MONDO_0009698)
Definitive
G6PC3
(HGNC:24861)
autosomal recessive severe congenital neutropenia due to G6PC3 deficiency
(MONDO_0012930)
Definitive
GPIHBP1
(HGNC:24945)
familial lipoprotein lipase deficiency
(MONDO_0009387)
Definitive
CTNS
(HGNC:2518)
cystinosis
(MONDO_0016239)
Definitive
CTNS
(HGNC:2518)
nephropathic cystinosis
(MONDO_0100151)
Definitive
CTSC
(HGNC:2528)
Papillon-Lefevre disease
(MONDO_0009490)
Definitive
AHDC1
(HGNC:25230)
AHDC1-related intellectual disability - obstructive sleep apnea - mild dysmorphism syndrome
(MONDO_0014358)
Definitive
CTSK
(HGNC:2536)
pycnodysostosis
(MONDO_0009940)
Strong
CTSC
(HGNC:2528)
Haim-Munk syndrome
(MONDO_0009491)
Strong
TANGO2
(HGNC:25439)
recurrent metabolic encephalomyopathic crises-rhabdomyolysis-cardiac arrhythmia-intellectual disability syndrome
(MONDO_0018820)
Definitive
C19orf12
(HGNC:25443)
neurodegeneration with brain iron accumulation 4
(MONDO_0013674)
Definitive
DARS2
(HGNC:25538)
leukoencephalopathy with brain stem and spinal cord involvement-high lactate syndrome
(MONDO_0012622)
Definitive
C19orf12
(HGNC:25443)
neurodegeneration with brain iron accumulation
(MONDO_0018307)
Strong
CUL3
(HGNC:2553)
pseudohypoaldosteronism type 2
(MONDO_0019162)
Definitive
BCORL1
(HGNC:25657)
acute myeloid leukemia
(MONDO_0018874)
Strong
FANCI GENE
(HGNC:25568)
Fanconi anemia
(MONDO_0019391)
Definitive
ARMC5
(HGNC:25781)
Cushing syndrome due to macronodular adrenal hyperplasia
(MONDO_0009049)
Definitive
ARMC5
(HGNC:25781)
Cushing syndrome
(MONDO_0018912)
Strong
DCAF17
(HGNC:25784)
Woodhouse-Sakati syndrome
(MONDO_0009419)
Definitive
CYBB
(HGNC:2578)
granulomatous disease, chronic, X-linked
(MONDO_0010600)
Definitive
CYBB
(HGNC:2578)
chronic granulomatous disease
(MONDO_0018305)
Definitive
CPLANE1
(HGNC:25801)
Joubert syndrome
(MONDO_0018772)
Strong
CYLD
(HGNC:2584)
familial cylindromatosis
(MONDO_0007565)
Definitive
CYLD
(HGNC:2584)
Brooke-Spiegler syndrome
(MONDO_0011512)
Definitive
TMEM127
(HGNC:26038)
paraganglioma
(MONDO_0000448)
Strong
SDHAF2
(HGNC:26034)
paraganglioma
(MONDO_0000448)
Moderate
TMEM127
(HGNC:26038)
pheochromocytoma
(MONDO_0008233)
Strong
CYP27A1
(HGNC:2605)
cerebrotendinous xanthomatosis
(MONDO_0008948)
Strong
CTC1
(HGNC:26169)
Coats plus syndrome
(MONDO_0012815)
Definitive
BBS10
(HGNC:26291)
Bardet-Biedl syndrome
(MONDO_0015229)
Definitive
HGSNAT
(HGNC:26527)
mucopolysaccharidosis type 3C
(MONDO_0009657)
Strong
DOK7
(HGNC:26594)
congenital myasthenic syndrome
(MONDO_0018940)
Definitive
DCX
(HGNC:2714)
lissencephaly spectrum disorders
(MONDO_0018838)
Definitive
AMER1
(HGNC:26837)
osteopathia striata with cranial sclerosis
(MONDO_0010310)
Definitive
DDC
(HGNC:2719)
aromatic L-amino acid decarboxylase deficiency
(MONDO_0012084)
Definitive
DCX
(HGNC:2714)
subcortical band heterotopia
(MONDO_0020491)
Definitive
RBM20
(HGNC:27424)
dilated cardiomyopathy
(MONDO_0005021)
Definitive
ESCO2
(HGNC:27230)
Roberts-SC phocomelia syndrome
(MONDO_0100253)
Definitive
STING1
(HGNC:27962)
STING-associated vasculopathy with onset in infancy
(MONDO_0014405)
Definitive
MFSD8
(HGNC:28486)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Definitive
DHH
(HGNC:2865)
disorder of sexual differentiation
(MONDO_0002145)
Strong
DGKE
(HGNC:2852)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Definitive
CYB5R3
(HGNC:2873)
methemoglobinemia
(MONDO_0001117)
Definitive
NIPBL
(HGNC:28862)
Cornelia de Lange syndrome
(MONDO_0016033)
Definitive
LEMD3
(HGNC:28887)
Buschke-Ollendorff syndrome
(MONDO_0008157)
Strong
DKC1
(HGNC:2890)
dyskeratosis congenita
(MONDO_0015780)
Definitive
LEMD3
(HGNC:28887)
osteopoikilosis
(MONDO_0001414)
Definitive
DKC1
(HGNC:2890)
dyskeratosis congenita, X-linked
(MONDO_0010584)
Definitive
DKC1
(HGNC:2890)
Hoyeraal-Hreidarsson syndrome
(MONDO_0018045)
Strong
WDR45
(HGNC:28912)
neurodegeneration with brain iron accumulation
(MONDO_0018307)
Definitive
WDR45
(HGNC:28912)
neurodegeneration with brain iron accumulation 5
(MONDO_0010476)
Strong
EDAR
(HGNC:2895)
hypohidrotic ectodermal dysplasia
(MONDO_0016535)
Definitive
DLD
(HGNC:2898)
pyruvate dehydrogenase E3 deficiency
(MONDO_0009529)
Definitive
PIEZO1
(HGNC:28993)
dehydrated hereditary stomatocytosis
(MONDO_0017910)
Definitive
IQSEC2
(HGNC:29059)
intellectual disability
(MONDO_0001071)
Definitive
IFT140
(HGNC:29077)
short-rib thoracic dysplasia 9 with or without polydactyly
(MONDO_0009964)
Definitive
DLK1
(HGNC:2907)
central precocious puberty
(MONDO_0019165)
Definitive
FAN1
(HGNC:29170)
karyomegalic interstitial nephritis
(MONDO_0013898)
Strong
ADSL
(HGNC:291)
adenylosuccinate lyase deficiency
(MONDO_0007068)
Definitive
TBC1D24
(HGNC:29203)
familial infantile myoclonic epilepsy
(MONDO_0011506)
Strong
TBC1D24
(HGNC:29203)
DOORS syndrome
(MONDO_0009079)
Strong
WDR35
(HGNC:29250)
cranioectodermal dysplasia
(MONDO_0009032)
Strong
CC2D2A
(HGNC:29253)
Joubert syndrome
(MONDO_0018772)
Definitive
EPG5
(HGNC:29331)
Vici syndrome
(MONDO_0009452)
Strong
DMPK
(HGNC:2933)
myotonic dystrophy type 1
(MONDO_0008056)
Definitive
DMPK
(HGNC:2933)
myotonic dystrophy
(MONDO_0016107)
Strong
ASXL3
(HGNC:29357)
severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome
(MONDO_0014205)
Definitive
SH3TC2
(HGNC:29427)
Charcot-Marie-Tooth disease type 4C
(MONDO_0011113)
Definitive
SH3TC2
(HGNC:29427)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Definitive
DNAH5
(HGNC:2950)
primary ciliary dyskinesia
(MONDO_0016575)
Definitive
DNAH11
(HGNC:2942)
primary ciliary dyskinesia
(MONDO_0016575)
Definitive
DYNC2H1
(HGNC:2962)
asphyxiating thoracic dystrophy 3
(MONDO_0013127)
Strong
GNPTAB
(HGNC:29670)
mucolipidosis type II
(MONDO_0009650)
Definitive
DNM2
(HGNC:2974)
autosomal dominant centronuclear myopathy
(MONDO_0008048)
Strong
DNM2
(HGNC:2974)
centronuclear myopathy
(MONDO_0018947)
Strong
BBS9
(HGNC:30000)
Bardet-Biedl syndrome
(MONDO_0015229)
Definitive
POLR3A
(HGNC:30074)
Wiedemann-Rautenstrauch syndrome
(MONDO_0009910)
Strong
POLR3A
(HGNC:30074)
leukodystrophy
(MONDO_0019046)
Definitive
SLC26A3
(HGNC:3018)
Bartter syndrome
(MONDO_0015231)
Refuted
SLC26A3
(HGNC:3018)
congenital secretory chloride diarrhea 1
(MONDO_0008964)
Definitive
SLC52A2
(HGNC:30224)
riboflavin transporter deficiency
(MONDO_0008891)
Definitive
ATN1
(HGNC:3033)
dentatorubral-pallidoluysian atrophy
(MONDO_0007435)
Definitive
DSC2
(HGNC:3036)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Definitive
DSG2
(HGNC:3049)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Definitive
SLC46A1
(HGNC:30521)
hereditary folate malabsorption
(MONDO_0009238)
Definitive
DSPP
(HGNC:3054)
dentinogenesis imperfecta
(MONDO_0018849)
Definitive
STRA6
(HGNC:30650)
Matthew-Wood syndrome
(MONDO_0011010)
Definitive
PNPLA2
(HGNC:30802)
neutral lipid storage myopathy
(MONDO_0012545)
Definitive
PNPLA2
(HGNC:30802)
triglyceride deposit cardiomyovasculopathy
(MONDO_0035423)
Strong
TRAPPC9
(HGNC:30832)
intellectual disability
(MONDO_0001071)
Strong
EFTUD2
(HGNC:30858)
mandibulofacial dysostosis-microcephaly syndrome
(MONDO_0012516)
Definitive
DYRK1A
(HGNC:3091)
DYRK1A-related intellectual disability syndrome
(MONDO_0013578)
Definitive
ECEL1
(HGNC:3147)
distal arthrogryposis type 5D
(MONDO_0014028)
Definitive
TYMP
(HGNC:3148)
mitochondrial neurogastrointestinal encephalomyopathy
(MONDO_0017575)
Definitive
ECHS1
(HGNC:3151)
Leigh syndrome
(MONDO_0009723)
Definitive
EDA
(HGNC:3157)
X-linked hypohidrotic ectodermal dysplasia
(MONDO_0010585)
Definitive
EDA
(HGNC:3157)
hypohidrotic ectodermal dysplasia
(MONDO_0016535)
Definitive
ECM1
(HGNC:3153)
lipoid proteinosis
(MONDO_0009530)
Definitive
EDNRB
(HGNC:3180)
Waardenburg syndrome type 4A
(MONDO_0010192)
Definitive
EDA
(HGNC:3157)
ectodermal dysplasia syndrome
(MONDO_0019287)
Strong
EDNRB
(HGNC:3180)
Waardenburg syndrome
(MONDO_0018094)
Strong
EDNRB
(HGNC:3180)
Hirschsprung disease
(MONDO_0018309)
Strong
AGL
(HGNC:321)
glycogen storage disease III
(MONDO_0009291)
Definitive
EFNB1
(HGNC:3226)
craniofrontonasal syndrome
(MONDO_0010570)
Definitive
EIF1AX
(HGNC:3250)
uveal melanoma
(MONDO_0006486)
Strong
EIF2AK3
(HGNC:3255)
Wolcott-Rallison syndrome
(MONDO_0009192)
Definitive
EIF2B2
(HGNC:3258)
leukoencephalopathy with vanishing white matter
(MONDO_0800448)
Strong
AGPAT2
(HGNC:325)
congenital generalized lipodystrophy
(MONDO_0006536)
Strong
EIF2B3
(HGNC:3259)
leukoencephalopathy with vanishing white matter
(MONDO_0800448)
Definitive
EIF2B5
(HGNC:3261)
leukoencephalopathy with vanishing white matter
(MONDO_0800448)
Definitive
AGRN
(HGNC:329)
congenital myasthenic syndrome
(MONDO_0018940)
Strong
EMD
(HGNC:3331)
Emery-Dreifuss muscular dystrophy
(MONDO_0016830)
Definitive
EPM2A
(HGNC:3413)
Lafora disease
(MONDO_0009697)
Definitive
ENG
(HGNC:3349)
hereditary hemorrhagic telangiectasia
(MONDO_0019180)
Definitive
AGXT
(HGNC:341)
primary hyperoxaluria type 1
(MONDO_0009823)
Definitive
ERCC8
(HGNC:3439)
Cockayne syndrome
(MONDO_0016006)
Definitive
AHCY
(HGNC:343)
hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase
(MONDO_0013404)
Strong
ERG
(HGNC:3446)
acute myeloid leukemia
(MONDO_0018874)
Moderate
ETFA
(HGNC:3481)
multiple acyl-CoA dehydrogenase deficiency
(MONDO_0009282)
Definitive
ETFDH
(HGNC:3483)
multiple acyl-CoA dehydrogenase deficiency
(MONDO_0009282)
Strong
EVC
(HGNC:3497)
Ellis-van Creveld syndrome
(MONDO_0009162)
Definitive
EXT1
(HGNC:3512)
hereditary multiple osteochondromas
(MONDO_0005508)
Definitive
MECOM
(HGNC:3498)
acute myeloid leukemia
(MONDO_0018874)
Definitive
EXT1
(HGNC:3512)
trichorhinophalangeal syndrome type II
(MONDO_0007874)
Strong
EXT2
(HGNC:3513)
hereditary multiple osteochondromas
(MONDO_0005508)
Definitive
EYA1
(HGNC:3519)
branchio-oto-renal syndrome
(MONDO_0007029)
Definitive
EYA1
(HGNC:3519)
branchiootic syndrome
(MONDO_0018878)
Strong
F10
(HGNC:3528)
factor X deficiency
(MONDO_0002247)
Definitive
F10
(HGNC:3528)
congenital factor X deficiency
(MONDO_0009212)
Definitive
F12
(HGNC:3530)
hereditary angioedema
(MONDO_0019623)
Strong
F13A1
(HGNC:3531)
congenital factor XIII deficiency
(MONDO_0018029)
Definitive
F13A1
(HGNC:3531)
factor XIII deficiency
(MONDO_0002241)
Strong
F7
(HGNC:3544)
factor VII deficiency
(MONDO_0002244)
Definitive
F7
(HGNC:3544)
congenital factor VII deficiency
(MONDO_0009211)
Definitive
F9
(HGNC:3551)
hemophilia B
(MONDO_0010604)
Definitive
FBN2
(HGNC:3604)
congenital contractural arachnodactyly
(MONDO_0007363)
Definitive
FBP1
(HGNC:3606)
fructose-1,6-bisphosphatase deficiency
(MONDO_0009251)
Definitive
FKTN
(HGNC:3622)
muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 4
(MONDO_0009678)
Definitive
FKTN
(HGNC:3622)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Definitive
FECH
(HGNC:3647)
erythropoietic protoporphyria
(MONDO_0001676)
Definitive
FGD1
(HGNC:3663)
Aarskog-Scott syndrome, X-linked
(MONDO_0010589)
Definitive
FGF14
(HGNC:3671)
spinocerebellar ataxia type 27
(MONDO_0012247)
Definitive
FGF23
(HGNC:3680)
autosomal dominant hypophosphatemic rickets
(MONDO_0008660)
Strong
FGF23
(HGNC:3680)
familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome
(MONDO_0100251)
Strong
FGG
(HGNC:3694)
familial dysfibrinogenemia
(MONDO_0014452)
Strong
FGF23
(HGNC:3680)
familial tumoral calcinosis
(MONDO_0018891)
Strong
FHL1
(HGNC:3702)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
FHL1
(HGNC:3702)
Emery-Dreifuss muscular dystrophy
(MONDO_0016830)
Definitive
FGG
(HGNC:3694)
congenital afibrinogenemia
(MONDO_0008737)
Definitive
FLI1
(HGNC:3749)
Ewing sarcoma
(MONDO_0012817)
Strong
FHL1
(HGNC:3702)
reducing body myopathy
(MONDO_0019948)
Definitive
FLT4
(HGNC:3767)
lymphatic malformation 1
(MONDO_0007919)
Definitive
FMO3
(HGNC:3771)
trimethylaminuria
(MONDO_0011182)
Definitive
FOLR1
(HGNC:3791)
cerebral folate deficiency
(MONDO_0100034)
Strong
FN1
(HGNC:3778)
fibronectin glomerulopathy
(MONDO_0007671)
Strong
FOXC2
(HGNC:3801)
lymphedema-distichiasis syndrome
(MONDO_0007922)
Definitive
FOXE1
(HGNC:3806)
congenital hypothyroidism
(MONDO_0018612)
Moderate
FOXG1
(HGNC:3811)
Rett syndrome
(MONDO_0010726)
Definitive
FOXF1
(HGNC:3809)
alveolar capillary dysplasia with misalignment of pulmonary veins
(MONDO_0009934)
Definitive
FOXG1
(HGNC:3811)
Rett syndrome, congenital variant
(MONDO_0013270)
Strong
FXN
(HGNC:3951)
Friedreich ataxia
(MONDO_0100339)
Definitive
FSHR
(HGNC:3969)
premature menopause
(MONDO_0001119)
Strong
ALAS2
(HGNC:397)
X-linked erythropoietic protoporphyria
(MONDO_0010420)
Strong
ALAS2
(HGNC:397)
X-linked sideroblastic anemia 1
(MONDO_0020721)
Definitive
FTL
(HGNC:3999)
hereditary hyperferritinemia with congenital cataracts
(MONDO_0010952)
Definitive
FTL
(HGNC:3999)
neuroferritinopathy
(MONDO_0011638)
Definitive
ALB
(HGNC:399)
congenital analbuminemia
(MONDO_0014449)
Definitive
ALB
(HGNC:399)
hyperthyroxinemia, familial dysalbuminemic
(MONDO_0014448)
Definitive
FUCA1
(HGNC:4006)
fucosidosis
(MONDO_0009254)
Definitive
FZD4
(HGNC:4042)
exudative vitreoretinopathy
(MONDO_0019516)
Definitive
SLC37A4
(HGNC:4061)
glycogen storage disease Ib
(MONDO_0009288)
Definitive
G6PC1
(HGNC:4056)
glycogen storage disease I
(MONDO_0002413)
Definitive
ALDH5A1
(HGNC:408)
succinic semialdehyde dehydrogenase deficiency
(MONDO_0010083)
Definitive
GALC
(HGNC:4115)
Krabbe disease
(MONDO_0009499)
Definitive
GALNS
(HGNC:4122)
mucopolysaccharidosis type 4A
(MONDO_0009659)
Definitive
GALNS
(HGNC:4122)
mucopolysaccharidosis type 4
(MONDO_0018938)
Definitive
GALNT3
(HGNC:4125)
familial tumoral calcinosis
(MONDO_0018891)
Definitive
GALNT3
(HGNC:4125)
familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome
(MONDO_0100251)
Definitive
GALT
(HGNC:4135)
classic galactosemia
(MONDO_0009258)
Definitive
GALT
(HGNC:4135)
galactosemia
(MONDO_0018116)
Definitive
GAN
(HGNC:4137)
giant axonal neuropathy
(MONDO_0000128)
Definitive
ALDOB
(HGNC:417)
hereditary fructose intolerance
(MONDO_0009249)
Definitive
GBE1
(HGNC:4180)
adult polyglucosan body disease
(MONDO_0009897)
Definitive
GAMT
(HGNC:4136)
guanidinoacetate methyltransferase deficiency
(MONDO_0012999)
Definitive
GBE1
(HGNC:4180)
glycogen storage disease due to glycogen branching enzyme deficiency
(MONDO_0009292)
Strong
GFAP
(HGNC:4235)
Alexander disease
(MONDO_0008752)
Definitive
GCH1
(HGNC:4193)
dystonia 5
(MONDO_0007495)
Definitive
GH1
(HGNC:4261)
isolated congenital growth hormone deficiency
(MONDO_0000050)
Definitive
GHR
(HGNC:4263)
Laron syndrome
(MONDO_0009877)
Definitive
GJB3
(HGNC:4285)
erythrokeratodermia variabilis
(MONDO_0017851)
Definitive
GJB6
(HGNC:4288)
Clouston syndrome
(MONDO_0007510)
Definitive
GCH1
(HGNC:4193)
Parkinson disease
(MONDO_0005180)
Moderate
GCDH
(HGNC:4189)
glutaryl-CoA dehydrogenase deficiency
(MONDO_0009281)
Definitive
GHR
(HGNC:4263)
growth hormone insensitivity syndrome
(MONDO_0015892)
Definitive
GDF5
(HGNC:4220)
acromesomelic dysplasia 2A
(MONDO_0008703)
Definitive
ALMS1
(HGNC:428)
Alstrom syndrome
(MONDO_0008763)
Definitive
GLDC
(HGNC:4313)
glycine encephalopathy
(MONDO_0011612)
Definitive
GLRA1
(HGNC:4326)
hyperekplexia
(MONDO_0017658)
Definitive
GLRA1
(HGNC:4326)
hereditary hyperekplexia
(MONDO_0021022)
Definitive
ALPL
(HGNC:438)
hypophosphatasia
(MONDO_0018570)
Definitive
GLUD1
(HGNC:4335)
hyperinsulinism-hyperammonemia syndrome
(MONDO_0011717)
Strong
GP1BA
(HGNC:4439)
platelet-type von Willebrand disease
(MONDO_0008332)
Strong
GNRHR
(HGNC:4421)
hypogonadotropic hypogonadism
(MONDO_0018555)
Definitive
GPC3
(HGNC:4451)
Simpson-Golabi-Behmel syndrome
(MONDO_0010731)
Definitive
GP9
(HGNC:4444)
Bernard-Soulier syndrome
(MONDO_0009276)
Definitive
SETX
(HGNC:445)
spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2
(MONDO_0018996)
Definitive
GP1BA
(HGNC:4439)
Bernard-Soulier syndrome
(MONDO_0009276)
Definitive
ALX4
(HGNC:450)
Potocki-Shaffer syndrome
(MONDO_0011022)
Strong
GPC3
(HGNC:4451)
Simpson-Golabi-Behmel syndrome type 1
(MONDO_0020602)
Definitive
GRIN2A
(HGNC:4585)
epilepsy
(MONDO_0005027)
Definitive
AMH
(HGNC:464)
persistent Mullerian duct syndrome
(MONDO_0009857)
Definitive
GSN
(HGNC:4620)
Finnish type amyloidosis
(MONDO_0007097)
Definitive
GTF2I
(HGNC:4659)
Williams syndrome
(MONDO_0008678)
Definitive
GUCY2D
(HGNC:4689)
Leber congenital amaurosis
(MONDO_0018998)
Strong
GUSB
(HGNC:4696)
mucopolysaccharidosis type 7
(MONDO_0009662)
Strong
HADHA
(HGNC:4801)
mitochondrial trifunctional protein deficiency
(MONDO_0012172)
Definitive
HADHB
(HGNC:4803)
mitochondrial trifunctional protein deficiency
(MONDO_0012172)
Definitive
HTT
(HGNC:4851)
Huntington disease
(MONDO_0007739)
Definitive
HESX1
(HGNC:4877)
panhypopituitarism
(MONDO_0019591)
Moderate
HTT
(HGNC:4851)
juvenile Huntington disease
(MONDO_0016621)
Definitive
HEXA
(HGNC:4878)
Tay-Sachs disease
(MONDO_0010100)
Definitive
HEXA
(HGNC:4878)
GM2 gangliosidosis
(MONDO_0017720)
Definitive
HJV
(HGNC:4887)
hereditary hemochromatosis
(MONDO_0006507)
Strong
HEXB
(HGNC:4879)
Sandhoff disease
(MONDO_0010006)
Strong
HJV
(HGNC:4887)
hemochromatosis type 2
(MONDO_0019257)
Strong
CFHR1
(HGNC:4888)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Strong
HGD
(HGNC:4892)
alkaptonuria
(MONDO_0008753)
Definitive
HIBCH
(HGNC:4908)
3-hydroxyisobutyryl-CoA hydrolase deficiency
(MONDO_0009603)
Strong
ANK1
(HGNC:492)
hereditary spherocytosis
(MONDO_0019350)
Strong
MNX1
(HGNC:4979)
Currarino triad
(MONDO_0008305)
Definitive
HLCS
(HGNC:4976)
holocarboxylase synthetase deficiency
(MONDO_0009666)
Definitive
HMBS
(HGNC:4982)
acute intermittent porphyria
(MONDO_0008294)
Definitive
HMBS
(HGNC:4982)
porphyria
(MONDO_0037939)
Definitive
HMGCL
(HGNC:5005)
3-hydroxy-3-methylglutaric aciduria
(MONDO_0009520)
Definitive
HOXA13
(HGNC:5102)
hand-foot-genital syndrome
(MONDO_0007698)
Definitive
HPGD
(HGNC:5154)
primary hypertrophic osteoarthropathy
(MONDO_0016620)
Strong
HOXD13
(HGNC:5136)
synpolydactyly
(MONDO_0021651)
Definitive
HPRT1
(HGNC:5157)
gout
(MONDO_0005393)
Strong
HPRT1
(HGNC:5157)
Lesch-Nyhan syndrome
(MONDO_0010298)
Definitive
HPRT1
(HGNC:5157)
hypoxanthine guanine phosphoribosyltransferase partial deficiency
(MONDO_0010299)
Definitive
HPS1
(HGNC:5163)
Hermansky-Pudlak syndrome
(MONDO_0019312)
Definitive
HR
(HGNC:5172)
atrichia with papular lesions
(MONDO_0008847)
Strong
HSD17B3
(HGNC:5212)
46,XY disorder of sex development
(MONDO_0020040)
Strong
HSD11B2
(HGNC:5209)
apparent mineralocorticoid excess
(MONDO_0009025)
Definitive
HSD17B4
(HGNC:5213)
d-bifunctional protein deficiency
(MONDO_0009855)
Definitive
HSD17B4
(HGNC:5213)
Perrault syndrome
(MONDO_0017312)
Moderate
HSD3B2
(HGNC:5218)
congenital adrenal hyperplasia
(MONDO_0018479)
Definitive
IDS
(HGNC:5389)
mucopolysaccharidosis type 2
(MONDO_0010674)
Definitive
IDUA
(HGNC:5391)
mucopolysaccharidosis type 1
(MONDO_0001586)
Definitive
HSPB1
(HGNC:5246)
Charcot-Marie-Tooth disease axonal type 2F
(MONDO_0011687)
Strong
IDUA
(HGNC:5391)
Hurler syndrome
(MONDO_0011758)
Definitive
HSPG2
(HGNC:5273)
Schwartz-Jampel syndrome
(MONDO_0009717)
Definitive
IDUA
(HGNC:5391)
mucopolysaccharidosis
(MONDO_0019249)
Definitive
HSPB1
(HGNC:5246)
distal hereditary motor neuropathy
(MONDO_0018894)
Strong
CFI
(HGNC:5394)
complement factor I deficiency
(MONDO_0012594)
Moderate
NOTCH2NLC
(HGNC:53924)
neuronal intranuclear inclusion disease
(MONDO_0011327)
Definitive
CFI
(HGNC:5394)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Strong
CFI
(HGNC:5394)
thrombotic microangiopathy
(MONDO_0019737)
Strong
IGHMBP2
(HGNC:5542)
autosomal recessive distal spinal muscular atrophy 1
(MONDO_0011436)
Definitive
AP3B1
(HGNC:566)
Hermansky-Pudlak syndrome
(MONDO_0019312)
Definitive
AP3B1
(HGNC:566)
Hermansky-Pudlak syndrome 2
(MONDO_0011997)
Strong
ABCC6
(HGNC:57)
autosomal recessive inherited pseudoxanthoma elasticum
(MONDO_0009925)
Definitive
ABCC6
(HGNC:57)
arterial calcification of infancy
(MONDO_0018870)
Strong
BIRC3
(HGNC:591)
B-cell chronic lymphocytic leukemia
(MONDO_0004948)
Moderate
XIAP
(HGNC:592)
X-linked lymphoproliferative disease due to XIAP deficiency
(MONDO_0010385)
Definitive
IGSF1
(HGNC:5948)
central congenital hypothyroidism
(MONDO_0016410)
Definitive
IKBKG
(HGNC:5961)
incontinentia pigmenti
(MONDO_0010631)
Definitive
IL2RG
(HGNC:6010)
T-B+ severe combined immunodeficiency due to gamma chain deficiency
(MONDO_0010315)
Definitive
IL10RA
(HGNC:5964)
inflammatory bowel disease
(MONDO_0005265)
Definitive
IL2RG
(HGNC:6010)
severe combined immunodeficiency
(MONDO_0015974)
Definitive
ABCC9
(HGNC:60)
hypertrichotic osteochondrodysplasia Cantu type
(MONDO_0009406)
Definitive
IRF6
(HGNC:6121)
popliteal pterygium syndrome
(MONDO_0017435)
Definitive
IRF6
(HGNC:6121)
van der Woude syndrome
(MONDO_0019508)
Definitive
ITGA2B
(HGNC:6138)
Glanzmann thrombasthenia
(MONDO_0100326)
Definitive
ITGA6
(HGNC:6142)
junctional epidermolysis bullosa with pyloric atresia
(MONDO_0009183)
Definitive
ITGB2
(HGNC:6155)
leukocyte adhesion deficiency
(MONDO_0017570)
Definitive
ITGB2
(HGNC:6155)
leukocyte adhesion deficiency 1
(MONDO_0007293)
Definitive
IVD
(HGNC:6186)
isovaleric acidemia
(MONDO_0009475)
Definitive
JUP
(HGNC:6207)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Definitive
KCNA1
(HGNC:6218)
episodic ataxia type 1
(MONDO_0008047)
Definitive
ANOS1
(HGNC:6211)
Kallmann syndrome
(MONDO_0018800)
Definitive
KCNJ1
(HGNC:6255)
Bartter disease type 2
(MONDO_0009424)
Definitive
KCNJ1
(HGNC:6255)
Bartter syndrome
(MONDO_0015231)
Definitive
APRT
(HGNC:626)
adenine phosphoribosyltransferase deficiency
(MONDO_0013869)
Definitive
KCNQ3
(HGNC:6297)
benign neonatal seizures
(MONDO_0016027)
Moderate
KIF5A
(HGNC:6323)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
KIF5A
(HGNC:6323)
hereditary spastic paraplegia 10
(MONDO_0011408)
Strong
AQP2
(HGNC:634)
nephrogenic diabetes insipidus
(MONDO_0016383)
Definitive
KIF5A
(HGNC:6323)
hereditary spastic paraplegia
(MONDO_0019064)
Definitive
MAFB
(HGNC:6408)
multicentric carpo-tarsal osteolysis with or without nephropathy
(MONDO_0008152)
Definitive
KRT10
(HGNC:6413)
epidermolytic ichthyosis
(MONDO_0007239)
Definitive
KRT14
(HGNC:6416)
epidermolysis bullosa simplex
(MONDO_0017610)
Definitive
KRT17
(HGNC:6427)
pachyonychia congenita
(MONDO_0016471)
Definitive
KRT16
(HGNC:6423)
pachyonychia congenita
(MONDO_0016471)
Definitive
KRT5
(HGNC:6442)
epidermolysis bullosa simplex
(MONDO_0017610)
Definitive
KRT6A
(HGNC:6443)
pachyonychia congenita
(MONDO_0016471)
Definitive
KRT9
(HGNC:6447)
palmoplantar keratoderma, epidermolytic
(MONDO_0968949)
Definitive
LAMA3
(HGNC:6483)
junctional epidermolysis bullosa
(MONDO_0017612)
Definitive
LAMB2
(HGNC:6487)
familial nephrotic syndrome
(MONDO_0002350)
Definitive
LAMB2
(HGNC:6487)
Pierson syndrome
(MONDO_0012184)
Strong
LAMB3
(HGNC:6490)
epidermolysis bullosa
(MONDO_0006541)
Definitive
LAMA1
(HGNC:6481)
ataxia - intellectual disability - oculomotor apraxia - cerebellar cysts syndrome
(MONDO_0014419)
Strong
LAMP2
(HGNC:6501)
Danon disease
(MONDO_0010281)
Definitive
LAMB3
(HGNC:6490)
junctional epidermolysis bullosa
(MONDO_0017612)
Definitive
LIPA
(HGNC:6617)
lysosomal acid lipase deficiency
(MONDO_0800449)
Definitive
LGI1
(HGNC:6572)
autosomal dominant epilepsy with auditory features
(MONDO_0010898)
Strong
LIPA
(HGNC:6617)
cholesteryl ester storage disease
(MONDO_0019149)
Definitive
LIPA
(HGNC:6617)
Wolman disease
(MONDO_0019148)
Definitive
ARG1
(HGNC:663)
hyperargininemia
(MONDO_0008814)
Definitive
RHOA
(HGNC:667)
angioimmunoblastic T-cell lymphoma
(MONDO_0004977)
Strong
LRP2
(HGNC:6694)
Donnai-Barrow syndrome
(MONDO_0009104)
Definitive
LRP4
(HGNC:6696)
Cenani-Lenz syndactyly syndrome
(MONDO_0008931)
Definitive
LZTR1
(HGNC:6742)
schwannomatosis
(MONDO_0008075)
Definitive
LZTR1
(HGNC:6742)
Noonan syndrome
(MONDO_0018997)
Definitive
MC2R
(HGNC:6930)
familial glucocorticoid deficiency
(MONDO_0008733)
Definitive
MCCC2
(HGNC:6937)
3-methylcrotonyl-CoA carboxylase deficiency
(MONDO_0018950)
Definitive
CD46
(HGNC:6953)
hemolytic-uremic syndrome
(MONDO_0001549)
Definitive
MERTK
(HGNC:7027)
retinitis pigmentosa
(MONDO_0019200)
Definitive
CD46
(HGNC:6953)
atypical hemolytic-uremic syndrome
(MONDO_0016244)
Strong
MKKS
(HGNC:7108)
McKusick-Kaufman syndrome
(MONDO_0009367)
Definitive
MKKS
(HGNC:7108)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
MKRN3
(HGNC:7114)
idiopathic central precocious puberty
(MONDO_0015713)
Definitive
MKRN3
(HGNC:7114)
central precocious puberty
(MONDO_0019165)
Definitive
MN1
(HGNC:7180)
acute myeloid leukemia
(MONDO_0018874)
Strong
MOCS1
(HGNC:7190)
sulfite oxidase deficiency due to molybdenum cofactor deficiency
(MONDO_0020480)
Definitive
MOCS2
(HGNC:7193)
sulfite oxidase deficiency due to molybdenum cofactor deficiency
(MONDO_0020480)
Definitive
MPV17
(HGNC:7224)
mitochondrial DNA depletion syndrome
(MONDO_0018158)
Definitive
ASAH1
(HGNC:735)
spinal muscular atrophy-progressive myoclonic epilepsy syndrome
(MONDO_0008045)
Definitive
ASAH1
(HGNC:735)
Farber lipogranulomatosis
(MONDO_0009218)
Definitive
MSX1
(HGNC:7391)
tooth agenesis
(MONDO_0005486)
Definitive
MTM1
(HGNC:7448)
X-linked myotubular myopathy
(MONDO_0010683)
Definitive
MTTP
(HGNC:7467)
abetalipoproteinemia
(MONDO_0008692)
Definitive
ASL
(HGNC:746)
argininosuccinic aciduria
(MONDO_0008815)
Definitive
MUSK
(HGNC:7525)
congenital myasthenic syndrome
(MONDO_0018940)
Strong
MUC1
(HGNC:7508)
autosomal dominant medullary cystic kidney disease with or without hyperuricemia
(MONDO_0008264)
Strong
MMUT
(HGNC:7526)
methylmalonic acidemia
(MONDO_0002012)
Definitive
ASNS
(HGNC:753)
congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome
(MONDO_0014258)
Definitive
MYB
(HGNC:7545)
adenoid cystic carcinoma
(MONDO_0004971)
Strong
MYCN
(HGNC:7559)
neuroblastoma
(MONDO_0005072)
Definitive
ASPA
(HGNC:756)
Canavan disease
(MONDO_0010079)
Definitive
MYL2
(HGNC:7583)
hypertrophic cardiomyopathy
(MONDO_0005045)
Definitive
ASS1
(HGNC:758)
citrullinemia type I
(MONDO_0008988)
Strong
ASS1
(HGNC:758)
citrullinemia
(MONDO_0015991)
Strong
MYO5B
(HGNC:7603)
microvillus inclusion disease
(MONDO_0009635)
Definitive
MYO7A
(HGNC:7606)
Usher syndrome type 1
(MONDO_0010168)
Definitive
MYO7A
(HGNC:7606)
Usher syndrome
(MONDO_0019501)
Definitive
MYOC
(HGNC:7610)
glaucoma
(MONDO_0005041)
Definitive
MYOC
(HGNC:7610)
open-angle glaucoma
(MONDO_0005338)
Definitive
MYOC
(HGNC:7610)
ocular hypertension
(MONDO_0006875)
Strong
MYOC
(HGNC:7610)
juvenile open angle glaucoma
(MONDO_0020367)
Strong
MYOC
(HGNC:7610)
OPTN-related open angle glaucoma
(MONDO_0100553)
Definitive
NAGLU
(HGNC:7632)
mucopolysaccharidosis type 3B
(MONDO_0009656)
Definitive
NCF1
(HGNC:7660)
chronic granulomatous disease
(MONDO_0018305)
Strong
NDP
(HGNC:7678)
Norrie disease
(MONDO_0010691)
Definitive
NDP
(HGNC:7678)
exudative vitreoretinopathy
(MONDO_0019516)
Definitive
NDUFV1
(HGNC:7716)
Leigh syndrome
(MONDO_0009723)
Definitive
NEB
(HGNC:7720)
nemaline myopathy
(MONDO_0018958)
Definitive
NEFL
(HGNC:7739)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
NEU1
(HGNC:7758)
sialidosis
(MONDO_0017734)
Definitive
NFIX
(HGNC:7788)
Marshall-Smith syndrome
(MONDO_0011244)
Strong
NFKB2
(HGNC:7795)
common variable immunodeficiency
(MONDO_0015517)
Strong
NFIX
(HGNC:7788)
Malan overgrowth syndrome
(MONDO_0013885)
Strong
NOG
(HGNC:7866)
proximal symphalangism
(MONDO_0008511)
Definitive
PNP
(HGNC:7892)
purine nucleoside phosphorylase deficiency
(MONDO_0013171)
Definitive
NHS
(HGNC:7820)
Nance-Horan syndrome
(MONDO_0010545)
Definitive
NPC1
(HGNC:7897)
Niemann-Pick disease type C
(MONDO_0018982)
Definitive
NPHP1
(HGNC:7905)
nephronophthisis
(MONDO_0019005)
Definitive
NNT
(HGNC:7863)
familial glucocorticoid deficiency
(MONDO_0008733)
Strong
NPHS1
(HGNC:7908)
familial nephrotic syndrome
(MONDO_0002350)
Definitive
NPHP3
(HGNC:7907)
nephronophthisis
(MONDO_0019005)
Definitive
NPR2
(HGNC:7944)
acromesomelic dysplasia 1, Maroteaux type
(MONDO_0011275)
Definitive
NPHS1
(HGNC:7908)
focal segmental glomerulosclerosis
(MONDO_0100313)
Strong
NR2E3
(HGNC:7974)
enhanced S-cone syndrome
(MONDO_0100288)
Definitive
NR2F1
(HGNC:7975)
Bosch-Boonstra-Schaaf optic atrophy syndrome
(MONDO_0014320)
Definitive
NPHS1
(HGNC:7908)
nephrotic syndrome
(MONDO_0005377)
Definitive
NR3C2
(HGNC:7979)
pseudohypoaldosteronism type 1
(MONDO_0019161)
Definitive
ATP1A1
(HGNC:799)
primary aldosteronism
(MONDO_0001422)
Strong
ATP1A1
(HGNC:799)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
FRMD7
(HGNC:8079)
congenital nystagmus
(MONDO_0005712)
Definitive
NUP98
(HGNC:8068)
acute myeloid leukemia
(MONDO_0018874)
Strong
OCRL
(HGNC:8108)
oculocerebrorenal syndrome
(MONDO_0010645)
Definitive
OAT
(HGNC:8091)
ornithine aminotransferase deficiency
(MONDO_0009796)
Definitive
OCRL
(HGNC:8108)
Dent disease
(MONDO_0015612)
Strong
ATP2A2
(HGNC:812)
Darier disease
(MONDO_0007417)
Definitive
ATP2A2
(HGNC:812)
acrokeratosis verruciformis
(MONDO_0007048)
Strong
OTC
(HGNC:8512)
urea cycle disorder
(MONDO_0004739)
Definitive
OTC
(HGNC:8512)
ornithine carbamoyltransferase deficiency
(MONDO_0010703)
Definitive
PAFAH1B1
(HGNC:8574)
Miller-Dieker lissencephaly syndrome
(MONDO_0009532)
Definitive
PABPN1
(HGNC:8565)
oculopharyngeal muscular dystrophy
(MONDO_0008116)
Definitive
OTOF
(HGNC:8515)
auditory neuropathy
(MONDO_0021944)
Definitive
PAX3
(HGNC:8617)
Waardenburg syndrome type 1
(MONDO_0008670)
Definitive
PAX3
(HGNC:8617)
Waardenburg syndrome
(MONDO_0018094)
Definitive
PAFAH1B1
(HGNC:8574)
lissencephaly spectrum disorders
(MONDO_0018838)
Definitive
PAX8
(HGNC:8622)
congenital hypothyroidism
(MONDO_0018612)
Strong
PAX9
(HGNC:8623)
tooth agenesis
(MONDO_0005486)
Strong
PCCA
(HGNC:8653)
propionic acidemia
(MONDO_0011628)
Definitive
PCCB
(HGNC:8654)
propionic acidemia
(MONDO_0011628)
Definitive
ATP7A
(HGNC:869)
occipital horn syndrome
(MONDO_0010572)
Strong
ATP7A
(HGNC:869)
Menkes disease
(MONDO_0010651)
Definitive
ATP6V0A4
(HGNC:866)
distal renal tubular acidosis
(MONDO_0015827)
Definitive
PDCD10
(HGNC:8761)
cerebral cavernous malformation
(MONDO_0000820)
Definitive
ATP7B
(HGNC:870)
Wilson disease
(MONDO_0010200)
Definitive
ALDH7A1
(HGNC:877)
pyridoxine-dependent epilepsy
(MONDO_0009945)
Definitive
PDE6B
(HGNC:8786)
retinitis pigmentosa
(MONDO_0019200)
Definitive
PDHA1
(HGNC:8806)
pyruvate dehydrogenase deficiency
(MONDO_0019169)
Strong
PDGFB
(HGNC:8800)
dermatofibrosarcoma protuberans
(MONDO_0011934)
Strong
PDGFB
(HGNC:8800)
basal ganglia calcification, idiopathic, 1
(MONDO_0024538)
Strong
PEPD
(HGNC:8840)
prolidase deficiency
(MONDO_0008221)
Definitive
PEX1
(HGNC:8850)
peroxisome biogenesis disorder
(MONDO_0019234)
Definitive
PEX1
(HGNC:8850)
Zellweger spectrum disorders
(MONDO_0019609)
Definitive
PFKM
(HGNC:8877)
glycogen storage disease VII
(MONDO_0009295)
Definitive
PGK1
(HGNC:8896)
glycogen storage disease due to phosphoglycerate kinase 1 deficiency
(MONDO_0010392)
Strong
PGM1
(HGNC:8905)
PGM1-congenital disorder of glycosylation
(MONDO_0013968)
Strong
PHEX
(HGNC:8918)
X-linked dominant hypophosphatemic rickets
(MONDO_0010619)
Definitive
PHEX
(HGNC:8918)
X-linked hypophosphatemic rickets
(MONDO_0020720)
Definitive
PHEX
(HGNC:8918)
hypophosphatemic rickets
(MONDO_0024300)
Definitive
PGM1
(HGNC:8905)
congenital disorder of glycosylation
(MONDO_0015286)
Definitive
PHKA2
(HGNC:8926)
disorder of glycogen metabolism
(MONDO_0002412)
Strong
PIGA
(HGNC:8957)
paroxysmal nocturnal hemoglobinuria
(MONDO_0100244)
Definitive
PIGN
(HGNC:8967)
multiple congenital anomalies-hypotonia-seizures syndrome 1
(MONDO_0013563)
Definitive
AVPR2
(HGNC:897)
nephrogenic syndrome of inappropriate antidiuresis
(MONDO_0010356)
Strong
AVPR2
(HGNC:897)
nephrogenic diabetes insipidus
(MONDO_0016383)
Definitive
ACADM
(HGNC:89)
medium chain acyl-CoA dehydrogenase deficiency
(MONDO_0008721)
Definitive
PITX2
(HGNC:9005)
Axenfeld-Rieger syndrome
(MONDO_0019187)
Definitive
PKD2
(HGNC:9009)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Definitive
PKLR
(HGNC:9020)
pyruvate kinase deficiency of red cells
(MONDO_0009950)
Definitive
PKP2
(HGNC:9024)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Definitive
PLA2G6
(HGNC:9039)
neurodegeneration with brain iron accumulation 2A
(MONDO_0024457)
Definitive
PLA2G6
(HGNC:9039)
neurodegeneration with brain iron accumulation
(MONDO_0018307)
Definitive
PLG
(HGNC:9071)
ligneous conjunctivitis
(MONDO_0100560)
Definitive
PLG
(HGNC:9071)
hereditary angioedema
(MONDO_0019623)
Strong
PLP1
(HGNC:9086)
Pelizeaus-Merzbacher spectrum disorder
(MONDO_0010714)
Definitive
PLOD1
(HGNC:9081)
Ehlers-Danlos syndrome, kyphoscoliotic type 1
(MONDO_0016002)
Strong
ACADS
(HGNC:90)
short chain acyl-CoA dehydrogenase deficiency
(MONDO_0008722)
Limited
PML
(HGNC:9113)
acute promyelocytic leukemia
(MONDO_0012883)
Definitive
PMM2
(HGNC:9115)
PMM2-congenital disorder of glycosylation
(MONDO_0008907)
Definitive
PLP1
(HGNC:9086)
hereditary spastic paraplegia 2
(MONDO_0010733)
Definitive
PMM2
(HGNC:9115)
congenital disorder of glycosylation
(MONDO_0015286)
Definitive
PHOX2B
(HGNC:9143)
neuroblastoma
(MONDO_0005072)
Strong
PHOX2B
(HGNC:9143)
central hypoventilation syndrome, congenital, 1, with or without Hirschsprung disease
(MONDO_0800026)
Definitive
PHOX2B
(HGNC:9143)
Hirschsprung disease
(MONDO_0018309)
Moderate
POR
(HGNC:9208)
congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency
(MONDO_0013310)
Definitive
POR
(HGNC:9208)
Antley-Bixler syndrome
(MONDO_0008803)
Definitive
POR
(HGNC:9208)
congenital adrenal hyperplasia
(MONDO_0018479)
Definitive
POLH
(HGNC:9181)
xeroderma pigmentosum
(MONDO_0019600)
Definitive
POU1F1
(HGNC:9210)
panhypopituitarism
(MONDO_0019591)
Definitive
PPT1
(HGNC:9325)
neuronal ceroid lipofuscinosis 1
(MONDO_0009744)
Definitive
CTSA
(HGNC:9251)
galactosialidosis
(MONDO_0009737)
Definitive
ACADVL
(HGNC:92)
very long chain acyl-CoA dehydrogenase deficiency
(MONDO_0008723)
Definitive
PPT1
(HGNC:9325)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Definitive
PPT1
(HGNC:9325)
infantile neuronal ceroid lipofuscinosis
(MONDO_0019261)
Definitive
PRKACA
(HGNC:9380)
Cushing syndrome
(MONDO_0018912)
Definitive
BAG3
(HGNC:939)
dilated cardiomyopathy
(MONDO_0005021)
Definitive
BAG3
(HGNC:939)
myofibrillar myopathy
(MONDO_0018943)
Definitive
ACAT1
(HGNC:93)
beta-ketothiolase deficiency
(MONDO_0008760)
Strong
PRKCG
(HGNC:9402)
spinocerebellar ataxia type 14
(MONDO_0011540)
Definitive
PROP1
(HGNC:9455)
panhypopituitarism
(MONDO_0019591)
Definitive
PRPS1
(HGNC:9462)
Arts syndrome
(MONDO_0010533)
Definitive
PRPS1
(HGNC:9462)
Charcot-Marie-Tooth disease X-linked recessive 5
(MONDO_0010699)
Strong
HTRA1
(HGNC:9476)
CARASIL syndrome
(MONDO_0010829)
Definitive
LONP1
(HGNC:9479)
diffuse large B-cell lymphoma
(MONDO_0018905)
Limited
PSEN2
(HGNC:9509)
Alzheimer disease
(MONDO_0004975)
Strong
PSEN2
(HGNC:9509)
familial Alzheimer disease
(MONDO_0100087)
Definitive
BBS1
(HGNC:966)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
CAVIN1
(HGNC:9688)
congenital generalized lipodystrophy type 4
(MONDO_0013225)
Strong
ALDH18A1
(HGNC:9722)
cutis laxa
(MONDO_0016175)
Moderate
PYGM
(HGNC:9726)
glycogen storage disease V
(MONDO_0009293)
Strong
QDPR
(HGNC:9752)
dihydropteridine reductase deficiency
(MONDO_0009862)
Definitive
RAB27A
(HGNC:9766)
Griscelli syndrome type 2
(MONDO_0011872)
Definitive
RAB27A
(HGNC:9766)
hemophagocytic syndrome
(MONDO_0015540)
Definitive
RAB27A
(HGNC:9766)
Griscelli syndrome
(MONDO_0018306)
Definitive
RAD21
(HGNC:9811)
Cornelia de Lange syndrome
(MONDO_0016033)
Strong
RAG1
(HGNC:9831)
Omenn syndrome
(MONDO_0011338)
Definitive
RAG1
(HGNC:9831)
severe combined immunodeficiency
(MONDO_0015974)
Definitive
RAG2
(HGNC:9832)
severe combined immunodeficiency
(MONDO_0015974)
Definitive
RARA
(HGNC:9864)
acute promyelocytic leukemia
(MONDO_0012883)
Definitive
RAI1
(HGNC:9834)
Smith-Magenis syndrome
(MONDO_0008434)
Definitive
BCKDHB
(HGNC:987)
maple syrup urine disease
(MONDO_0009563)
Definitive
RASA1
(HGNC:9871)
capillary malformation-arteriovenous malformation syndrome
(MONDO_0012016)
Definitive
RBM10
(HGNC:9896)
TARP syndrome
(MONDO_0010711)
Definitive
RDH5
(HGNC:9940)
fundus albipunctatus
(MONDO_0007639)
Definitive
RGS9
(HGNC:10004)
bradyopsia
(MONDO_0012033)
Limited
RHAG
(HGNC:10006)
overhydrated hereditary stomatocytosis
(MONDO_0008493)
Limited
RHO
(HGNC:10012)
congenital stationary night blindness
(MONDO_0016293)
Moderate
GRK1
(HGNC:10013)
Oguchi disease-2
(MONDO_0013259)
Strong
RLBP1
(HGNC:10024)
fundus albipunctatus
(MONDO_0007639)
Limited
RIPK1
(HGNC:10019)
autoinflammation with episodic fever and lymphadenopathy
(MONDO_0030018)
Definitive
RLBP1
(HGNC:10024)
retinitis punctata albescens
(MONDO_0018877)
Strong
RLBP1
(HGNC:10024)
Newfoundland cone-rod dystrophy
(MONDO_0011839)
Moderate
BCS1L
(HGNC:1020)
Bjornstad syndrome
(MONDO_0009872)
Moderate
ROBO1
(HGNC:10249)
pituitary stalk interruption syndrome
(MONDO_0019828)
Moderate
RLBP1
(HGNC:10024)
retinitis pigmentosa
(MONDO_0019200)
Strong
BCS1L
(HGNC:1020)
GRACILE syndrome
(MONDO_0011308)
Definitive
BCS1L
(HGNC:1020)
Leigh syndrome
(MONDO_0009723)
Moderate
RPE65
(HGNC:10294)
Leber congenital amaurosis 2
(MONDO_0008765)
Definitive
BCS1L
(HGNC:1020)
mitochondrial complex III deficiency
(MONDO_0015448)
Strong
RPL26
(HGNC:10327)
Diamond-Blackfan anemia
(MONDO_0015253)
Limited
RPL35
(HGNC:10344)
Diamond-Blackfan anemia
(MONDO_0015253)
Limited
RPL35A
(HGNC:10345)
Diamond-Blackfan anemia
(MONDO_0015253)
Definitive
RPL3L
(HGNC:10351)
dilated cardiomyopathy
(MONDO_0005021)
Strong
RPL5
(HGNC:10360)
Diamond-Blackfan anemia
(MONDO_0015253)
Definitive
RPS10
(HGNC:10383)
Diamond-Blackfan anemia
(MONDO_0015253)
Definitive
RPGR
(HGNC:10295)
cone-rod dystrophy
(MONDO_0015993)
Strong
RPS20
(HGNC:10405)
Diamond-Blackfan anemia
(MONDO_0015253)
Moderate
CNNM2
(HGNC:103)
hypomagnesemia, seizures, and intellectual disability 1
(MONDO_0020787)
Strong
ROR2
(HGNC:10257)
brachydactyly type B1
(MONDO_0007220)
Strong
RPS26
(HGNC:10414)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
RPS24
(HGNC:10411)
Diamond-Blackfan anemia
(MONDO_0015253)
Moderate
RPS6KA3
(HGNC:10432)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Limited
RPS6KB1
(HGNC:10436)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
RPIA
(HGNC:10297)
ribose-5-P isomerase deficiency
(MONDO_0012073)
Moderate
ROM1
(HGNC:10254)
retinitis pigmentosa
(MONDO_0019200)
Limited
RRAS
(HGNC:10447)
Noonan syndrome
(MONDO_0018997)
Limited
RPS20
(HGNC:10405)
familial colorectal cancer type X
(MONDO_0018604)
Limited
BGN
(HGNC:1044)
Meester-Loeys syndrome
(MONDO_0010515)
Strong
RPL21
(HGNC:10313)
hypotrichosis simplex
(MONDO_0018914)
Moderate
RORB
(HGNC:10259)
epilepsy
(MONDO_0005027)
Strong
ROR2
(HGNC:10257)
autosomal recessive Robinow syndrome
(MONDO_0009999)
Definitive
RS1
(HGNC:10457)
retinoschisis
(MONDO_0004579)
Definitive
RPE65
(HGNC:10294)
severe early-childhood-onset retinal dystrophy
(MONDO_0009549)
Definitive
RPE65
(HGNC:10294)
retinitis pigmentosa
(MONDO_0019200)
Definitive
RPL11
(HGNC:10301)
Diamond-Blackfan anemia
(MONDO_0015253)
Definitive
RYR1
(HGNC:10483)
central core myopathy
(MONDO_0007294)
Definitive
CLIP1
(HGNC:10461)
intellectual disability
(MONDO_0001071)
Limited
RYR1
(HGNC:10483)
lethal multiple pterygium syndrome
(MONDO_0009668)
Limited
RUNX1
(HGNC:10471)
hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with RUNX1
(MONDO_0100083)
Definitive
RYR1
(HGNC:10483)
malignant hyperthermia, susceptibility to, 1
(MONDO_0007783)
Definitive
RYR1
(HGNC:10483)
malignant hyperthermia of anesthesia
(MONDO_0018493)
Definitive
RYR1
(HGNC:10483)
congenital multicore myopathy with external ophthalmoplegia
(MONDO_0009712)
Definitive
RPS26
(HGNC:10414)
Diamond-Blackfan anemia 10
(MONDO_0013217)
Strong
RYR2
(HGNC:10484)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Strong
RYR2
(HGNC:10484)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
RYR2
(HGNC:10484)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Strong
RYR1
(HGNC:10483)
King-Denborough syndrome
(MONDO_0020485)
Moderate
RYR3
(HGNC:10485)
developmental and epileptic encephalopathy
(MONDO_0100062)
Moderate
RYR2
(HGNC:10484)
catecholaminergic polymorphic ventricular tachycardia 1
(MONDO_0011484)
Definitive
BIK
(HGNC:1051)
prostate cancer
(MONDO_0008315)
Moderate
SAG
(HGNC:10521)
Oguchi disease
(MONDO_0019152)
Definitive
SARDH
(HGNC:10536)
sarcosinemia
(MONDO_0010008)
Limited
SAG
(HGNC:10521)
retinitis pigmentosa
(MONDO_0019200)
Refuted
BIN1
(HGNC:1052)
autosomal dominant centronuclear myopathy
(MONDO_0008048)
Strong
SATB1
(HGNC:10541)
developmental delay with dysmorphic facies and dental anomalies
(MONDO_0030988)
Strong
SBF1
(HGNC:10542)
Charcot-Marie-Tooth disease type 4B3
(MONDO_0014117)
Limited
MSMO1
(HGNC:10545)
microcephaly-congenital cataract-psoriasiform dermatitis syndrome
(MONDO_0014793)
Strong
BIN1
(HGNC:1052)
centronuclear myopathy
(MONDO_0018947)
Definitive
SATB1
(HGNC:10541)
neurodevelopmental disorder
(MONDO_0700092)
Strong
ATXN1
(HGNC:10548)
spinocerebellar ataxia type 1
(MONDO_0008119)
Strong
ATXN10
(HGNC:10549)
spinocerebellar ataxia type 10
(MONDO_0011330)
Definitive
ATXN7
(HGNC:10560)
autosomal dominant cerebellar ataxia type II
(MONDO_0016163)
Strong
ATXN2
(HGNC:10555)
spinocerebellar ataxia type 2
(MONDO_0008458)
Definitive
BLK
(HGNC:1057)
systemic lupus erythematosus
(MONDO_0007915)
Strong
BLK
(HGNC:1057)
maturity-onset diabetes of the young
(MONDO_0018911)
Limited
BLK
(HGNC:1057)
monogenic diabetes
(MONDO_0015967)
Limited
SCN10A
(HGNC:10582)
Brugada syndrome
(MONDO_0015263)
Strong
SCN1A
(HGNC:10585)
migraine, familial hemiplegic, 3
(MONDO_0012320)
Strong
SCN1A
(HGNC:10585)
myoclonic-astatic epilepsy
(MONDO_0016025)
Limited
SCN1A
(HGNC:10585)
familial hemiplegic migraine
(MONDO_0000700)
Strong
SCN1A
(HGNC:10585)
Lennox-Gastaut syndrome
(MONDO_0016532)
Limited
SCN1A
(HGNC:10585)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
SCN1A
(HGNC:10585)
malignant migrating partial seizures of infancy
(MONDO_0017385)
Limited
SCN1A
(HGNC:10585)
generalized epilepsy with febrile seizures plus
(MONDO_0018214)
Definitive
SCN1A
(HGNC:10585)
Dravet syndrome
(MONDO_0100135)
Definitive
SCN1B
(HGNC:10586)
developmental and epileptic encephalopathy
(MONDO_0100062)
Moderate
SCN1B
(HGNC:10586)
generalized epilepsy with febrile seizures plus
(MONDO_0018214)
Strong
SCN2A
(HGNC:10588)
intellectual disability
(MONDO_0001071)
Strong
SCN2A
(HGNC:10588)
developmental and epileptic encephalopathy
(MONDO_0100062)
Definitive
SCN2A
(HGNC:10588)
malignant migrating partial seizures of infancy
(MONDO_0017385)
Limited
SCN2A
(HGNC:10588)
seizures, benign familial infantile, 3
(MONDO_0011904)
Strong
SCN2A
(HGNC:10588)
benign familial infantile epilepsy
(MONDO_0017615)
Moderate
SCN2A
(HGNC:10588)
West syndrome
(MONDO_0018097)
Moderate
SCN2B
(HGNC:10589)
Brugada syndrome
(MONDO_0015263)
Limited
BLM
(HGNC:1058)
breast cancer
(MONDO_0007254)
Disputed
SCN4A
(HGNC:10591)
paramyotonia congenita of Von Eulenburg
(MONDO_0008195)
Definitive
BLM
(HGNC:1058)
osteosarcoma
(MONDO_0009807)
Limited
BLM
(HGNC:1058)
Bloom syndrome
(MONDO_0008876)
Definitive
SCN4A
(HGNC:10591)
hypokalemic periodic paralysis
(MONDO_0008223)
Strong
SCN4A
(HGNC:10591)
hyperkalemic periodic paralysis
(MONDO_0008224)
Definitive
BLM
(HGNC:1058)
hereditary nonpolyposis colon cancer
(MONDO_0018630)
Limited
SCN4A
(HGNC:10591)
hypokalemic periodic paralysis, type 2
(MONDO_0013234)
Moderate
SCN4A
(HGNC:10591)
potassium-aggravated myotonia
(MONDO_0018959)
Definitive
SCN3A
(HGNC:10590)
developmental and epileptic encephalopathy
(MONDO_0100062)
Moderate
SCN4B
(HGNC:10592)
long QT syndrome
(MONDO_0002442)
Limited
SCN4A
(HGNC:10591)
congenital myopathy
(MONDO_0019952)
Strong
SCN5A
(HGNC:10593)
short QT syndrome
(MONDO_0000453)
Disputed
SCN4A
(HGNC:10591)
myotonia permanens
(MONDO_0020482)
Strong
SCN5A
(HGNC:10593)
dilated cardiomyopathy
(MONDO_0005021)
Strong
SCN5A
(HGNC:10593)
progressive familial heart block, type 1A
(MONDO_0007240)
Moderate
SCN5A
(HGNC:10593)
atrial standstill
(MONDO_0015281)
Moderate
SCN5A
(HGNC:10593)
Brugada syndrome
(MONDO_0015263)
Definitive
SCN5A
(HGNC:10593)
familial sick sinus syndrome
(MONDO_0012061)
Strong
SCN5A
(HGNC:10593)
long QT syndrome 3
(MONDO_0011377)
Definitive
SCN5A
(HGNC:10593)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
SCN5A
(HGNC:10593)
familial atrial fibrillation
(MONDO_0018054)
Limited
SCN5A
(HGNC:10593)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Disputed
SCN5A
(HGNC:10593)
familial long QT syndrome
(MONDO_0019171)
Strong
SCN5A
(HGNC:10593)
paroxysmal familial ventricular fibrillation
(MONDO_0100234)
Moderate
SCN8A
(HGNC:10596)
cognitive impairment with or without cerebellar ataxia
(MONDO_0013680)
Moderate
SCN8A
(HGNC:10596)
developmental and epileptic encephalopathy, 13
(MONDO_0013801)
Moderate
SCN8A
(HGNC:10596)
benign familial infantile epilepsy
(MONDO_0017615)
Moderate
SCN9A
(HGNC:10597)
primary erythermalgia
(MONDO_0007571)
Definitive
SCN9A
(HGNC:10597)
paroxysmal extreme pain disorder
(MONDO_0008179)
Definitive
SCN9A
(HGNC:10597)
channelopathy-associated congenital insensitivity to pain, autosomal recessive
(MONDO_0009459)
Definitive
SCN9A
(HGNC:10597)
epilepsy
(MONDO_0005027)
Moderate
SCNN1A
(HGNC:10599)
Brugada syndrome
(MONDO_0015263)
Limited
SCNN1G
(HGNC:10602)
pseudohypoaldosteronism, type IB1, autosomal recessive
(MONDO_0009917)
Limited
SCNN1A
(HGNC:10599)
pseudohypoaldosteronism, type IB1, autosomal recessive
(MONDO_0009917)
Strong
SCNN1B
(HGNC:10600)
pseudohypoaldosteronism, type IB1, autosomal recessive
(MONDO_0009917)
Limited
SCO2
(HGNC:10604)
Leigh syndrome
(MONDO_0009723)
Definitive
SCP2
(HGNC:10606)
sterol carrier protein 2 deficiency
(MONDO_0013391)
Limited
AIMP1
(HGNC:10648)
hypomyelinating leukodystrophy 3
(MONDO_0009843)
Limited
SCO1
(HGNC:10603)
mitochondrial disease
(MONDO_0044970)
Moderate
TSHZ1
(HGNC:10669)
congenital vertical talus
(MONDO_0008652)
Moderate
TSHZ1
(HGNC:10669)
aural atresia, congenital
(MONDO_0011921)
Strong
SDHA
(HGNC:10680)
Leigh syndrome
(MONDO_0009723)
Strong
SDCCAG8
(HGNC:10671)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
SDCCAG8
(HGNC:10671)
Senior-Loken syndrome
(MONDO_0017842)
Limited
SDHA
(HGNC:10680)
gastrointestinal stromal tumor
(MONDO_0011719)
Strong
SDHA
(HGNC:10680)
mitochondrial complex II deficiency, nuclear type 1
(MONDO_0100294)
Strong
SDHB
(HGNC:10681)
pheochromocytoma
(MONDO_0008233)
Strong
SDHB
(HGNC:10681)
renal cell carcinoma
(MONDO_0005086)
Strong
SDHB
(HGNC:10681)
gastrointestinal stromal tumor
(MONDO_0011719)
Strong
SDHB
(HGNC:10681)
Carney-Stratakis syndrome
(MONDO_0011740)
Strong
SDHB
(HGNC:10681)
Cowden disease
(MONDO_0016063)
Limited
SDHB
(HGNC:10681)
mitochondrial disease
(MONDO_0044970)
Strong
SDHC
(HGNC:10682)
renal cell carcinoma
(MONDO_0005086)
Moderate
SDHC
(HGNC:10682)
Cowden disease
(MONDO_0016063)
Limited
SDHC
(HGNC:10682)
Carney-Stratakis syndrome
(MONDO_0011740)
Moderate
SDHD
(HGNC:10683)
renal cell carcinoma
(MONDO_0005086)
Limited
SDHC
(HGNC:10682)
mitochondrial disease
(MONDO_0044970)
Limited
SDHD
(HGNC:10683)
paragangliomas 1
(MONDO_0008192)
Definitive
SDHD
(HGNC:10683)
pheochromocytoma
(MONDO_0008233)
Definitive
SDHD
(HGNC:10683)
mitochondrial disease
(MONDO_0044970)
Limited
SDHD
(HGNC:10683)
Carney-Stratakis syndrome
(MONDO_0011740)
Strong
BMP2
(HGNC:1069)
brachydactyly type A2
(MONDO_0007216)
Strong
SDHD
(HGNC:10683)
Cowden disease
(MONDO_0016063)
Limited
SEC23B
(HGNC:10702)
Cowden disease
(MONDO_0016063)
Moderate
SDHC
(HGNC:10682)
gastrointestinal stromal tumor
(MONDO_0011719)
Strong
SEC23B
(HGNC:10702)
congenital dyserythropoietic anemia type 2
(MONDO_0009134)
Definitive
SEC23B
(HGNC:10702)
congenital dyserythropoietic anemia
(MONDO_0019403)
Definitive
SEC24D
(HGNC:10706)
Cole-Carpenter syndrome 2
(MONDO_0014573)
Limited
SEC24D
(HGNC:10706)
Cole-Carpenter syndrome
(MONDO_0016085)
Limited
SELENBP1
(HGNC:10719)
schizophrenia
(MONDO_0005090)
Limited
SEMA4A
(HGNC:10729)
cone-rod dystrophy
(MONDO_0015993)
Limited
SEMA4A
(HGNC:10729)
familial colorectal cancer type X
(MONDO_0018604)
Strong
BMP4
(HGNC:1071)
Stickler syndrome
(MONDO_0019354)
Limited
BMPR1A
(HGNC:1076)
hereditary mixed polyposis syndrome
(MONDO_0011023)
Strong
SF3B4
(HGNC:10771)
Nager acrofacial dysostosis
(MONDO_0007943)
Definitive
SET
(HGNC:10760)
intellectual disability
(MONDO_0001071)
Strong
BMPR1A
(HGNC:1076)
juvenile polyposis syndrome
(MONDO_0017380)
Definitive
SEMA3A
(HGNC:10723)
Kallmann syndrome
(MONDO_0018800)
Strong
SEMA3A
(HGNC:10723)
Brugada syndrome
(MONDO_0015263)
Limited
SEMA3E
(HGNC:10727)
CHARGE syndrome
(MONDO_0008965)
Limited
SEMA3E
(HGNC:10727)
Kallmann syndrome
(MONDO_0018800)
Moderate
SEMA4A
(HGNC:10729)
retinitis pigmentosa
(MONDO_0019200)
Limited
SFRP4
(HGNC:10778)
Pyle disease
(MONDO_0009943)
Strong
SF3B4
(HGNC:10771)
acrofacial dysostosis Rodriguez type
(MONDO_0008714)
Strong
BMPR1B
(HGNC:1077)
brachydactyly type A1
(MONDO_0007215)
Limited
BMPR1B
(HGNC:1077)
pulmonary arterial hypertension
(MONDO_0015924)
Moderate
BMPR1B
(HGNC:1077)
acromesomelic dysplasia 2A
(MONDO_0008703)
Strong
SFTPB
(HGNC:10801)
surfactant metabolism dysfunction, pulmonary, 1
(MONDO_0009929)
Strong
BMPR2
(HGNC:1078)
heritable pulmonary arterial hypertension
(MONDO_0017148)
Definitive
BMPR2
(HGNC:1078)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
BMPR2
(HGNC:1078)
congenital heart disease
(MONDO_0005453)
Limited
SFTPA2
(HGNC:10799)
interstitial lung disease 2
(MONDO_0800029)
Strong
SGCD
(HGNC:10807)
autosomal recessive limb-girdle muscular dystrophy type 2F
(MONDO_0011028)
Moderate
SGCA
(HGNC:10805)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Strong
SGCD
(HGNC:10807)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Moderate
SGK3
(HGNC:10812)
hypophosphatemic rickets
(MONDO_0024300)
Limited
SGCG
(HGNC:10809)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Limited
SGCB
(HGNC:10806)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Strong
SH2D1A
(HGNC:10820)
X-linked lymphoproliferative disease due to SH2D1A deficiency
(MONDO_0024551)
Strong
SGPL1
(HGNC:10817)
nephrotic syndrome 14
(MONDO_0033203)
Strong
BMPR1B
(HGNC:1077)
brachydactyly type A2
(MONDO_0007216)
Strong
SH3BP2
(HGNC:10825)
cherubism
(MONDO_0007315)
Definitive
SGCD
(HGNC:10807)
dilated cardiomyopathy
(MONDO_0005021)
Limited
SHH
(HGNC:10848)
solitary median maxillary central incisor syndrome
(MONDO_0007819)
Limited
SHH
(HGNC:10848)
triphalangeal thumb-polysyndactyly syndrome
(MONDO_0017454)
Limited
SHOX
(HGNC:10853)
SHOX-related short stature
(MONDO_0010367)
Definitive
ST8SIA2
(HGNC:10870)
schizophrenia
(MONDO_0005090)
Limited
ST3GAL3
(HGNC:10866)
West syndrome
(MONDO_0018097)
Moderate
SIX3
(HGNC:10889)
holoprosencephaly
(MONDO_0016296)
Definitive
SIX1
(HGNC:10887)
branchiootic syndrome
(MONDO_0018878)
Strong
SKIC2
(HGNC:10898)
trichohepatoenteric syndrome
(MONDO_0009105)
Definitive
SIX1
(HGNC:10887)
branchio-oto-renal syndrome
(MONDO_0007029)
Moderate
SIX5
(HGNC:10891)
branchio-oto-renal syndrome
(MONDO_0007029)
Limited
VPS4B
(HGNC:10895)
dentin dysplasia type I
(MONDO_0007436)
Limited
SLC10A1
(HGNC:10905)
hypercholanemia, familial, 2
(MONDO_0031003)
Definitive
SLC11A2
(HGNC:10908)
microcytic anemia with liver iron overload
(MONDO_0008787)
Strong
SLC12A2
(HGNC:10911)
syndromic intellectual disability
(MONDO_0000508)
Moderate
DST
(HGNC:1090)
hereditary sensory and autonomic neuropathy type 6
(MONDO_0013839)
Moderate
SLC12A2
(HGNC:10911)
schizophrenia
(MONDO_0005090)
Limited
SLC11A1
(HGNC:10907)
cystic fibrosis
(MONDO_0009061)
Limited
STIL
(HGNC:10879)
holoprosencephaly
(MONDO_0016296)
Limited
SLC12A3
(HGNC:10912)
Gitelman syndrome
(MONDO_0009904)
Definitive
SLC16A1
(HGNC:10922)
exercise-induced hyperinsulinism
(MONDO_0012396)
Strong
SLC16A1
(HGNC:10922)
ketoacidosis due to monocarboxylate transporter-1 deficiency
(MONDO_0014490)
Strong
SLC17A5
(HGNC:10933)
free sialic acid storage disease
(MONDO_0019366)
Moderate
STIL
(HGNC:10879)
autosomal recessive primary microcephaly
(MONDO_0016660)
Moderate
SLC17A5
(HGNC:10933)
free sialic acid storage disease, infantile form
(MONDO_0010027)
Strong
SLC12A6
(HGNC:10914)
agenesis of the corpus callosum with peripheral neuropathy
(MONDO_0000902)
Definitive
SLC18A2
(HGNC:10935)
schizophrenia
(MONDO_0005090)
Limited
SLC18A3
(HGNC:10936)
fetal akinesia deformation sequence 1
(MONDO_0100101)
Limited
SLC18A2
(HGNC:10935)
brain dopamine-serotonin vesicular transport disease
(MONDO_0018130)
Definitive
SLC1A1
(HGNC:10939)
hot water reflex epilepsy
(MONDO_0013229)
Moderate
SLC1A4
(HGNC:10942)
spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome
(MONDO_0014725)
Strong
SLC1A3
(HGNC:10941)
episodic ataxia type 6
(MONDO_0012982)
Strong
SLCO2A1
(HGNC:10955)
chronic enteropathy associated with SLCO2A1 gene
(MONDO_0018766)
Definitive
SLCO2A1
(HGNC:10955)
hypertrophic osteoarthropathy, primary, autosomal recessive, 2
(MONDO_0013756)
Strong
SLCO1B1
(HGNC:10959)
Rotor syndrome
(MONDO_0009379)
Definitive
SLC22A5
(HGNC:10969)
short QT syndrome
(MONDO_0000453)
Limited
SLCO1B3
(HGNC:10961)
Rotor syndrome
(MONDO_0009379)
Definitive
SLC24A4
(HGNC:10978)
amelogenesis imperfecta type 2
(MONDO_0015048)
Definitive
SLC25A1
(HGNC:10979)
mitochondrial disease
(MONDO_0044970)
Limited
SLC25A1
(HGNC:10979)
D,L-2-hydroxyglutaric aciduria
(MONDO_0014072)
Strong
BRAF
(HGNC:1097)
Noonan syndrome with multiple lentigines
(MONDO_0007893)
Limited
BRAF
(HGNC:1097)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Definitive
BRAF
(HGNC:1097)
Costello syndrome
(MONDO_0009026)
Limited
BRAF
(HGNC:1097)
anaplastic astrocytoma
(MONDO_0016684)
Moderate
SLC25A10
(HGNC:10980)
mitochondrial disease
(MONDO_0044970)
Limited
BRAF
(HGNC:1097)
Noonan syndrome
(MONDO_0018997)
Moderate
SLC25A13
(HGNC:10983)
neonatal intrahepatic cholestasis due to citrin deficiency
(MONDO_0011601)
Definitive
SLC25A12
(HGNC:10982)
developmental and epileptic encephalopathy, 39
(MONDO_0013056)
Moderate
SLC25A13
(HGNC:10983)
citrin deficiency
(MONDO_0016602)
Definitive
SLC25A12
(HGNC:10982)
mitochondrial disease
(MONDO_0044970)
Moderate
SLC25A13
(HGNC:10983)
citrullinemia type II
(MONDO_0016603)
Definitive
SLC25A4
(HGNC:10990)
Leigh syndrome
(MONDO_0009723)
Limited
SLC25A15
(HGNC:10985)
ornithine translocase deficiency
(MONDO_0009393)
Strong
SLC25A5
(HGNC:10991)
intellectual disability
(MONDO_0001071)
Limited
SLC26A2
(HGNC:10994)
achondrogenesis type IB
(MONDO_0010966)
Strong
SLC26A2
(HGNC:10994)
multiple epiphyseal dysplasia type 4
(MONDO_0009189)
Definitive
SLC25A4
(HGNC:10990)
mitochondrial disease
(MONDO_0044970)
Strong
SLC2A1
(HGNC:11005)
GLUT1 deficiency syndrome
(MONDO_0000188)
Definitive
SLC27A4
(HGNC:10998)
ichthyosis prematurity syndrome
(MONDO_0012089)
Definitive
SLC2A1
(HGNC:11005)
childhood absence epilepsy
(MONDO_0010826)
Limited
SLC26A2
(HGNC:10994)
atelosteogenesis type II
(MONDO_0009727)
Definitive
SLC2A1
(HGNC:11005)
childhood onset GLUT1 deficiency syndrome 2
(MONDO_0012805)
Definitive
SLC2A1
(HGNC:11005)
encephalopathy due to GLUT1 deficiency
(MONDO_0011724)
Definitive
SLC2A2
(HGNC:11006)
glycogen storage disease due to GLUT2 deficiency
(MONDO_0009216)
Definitive
SLC2A2
(HGNC:11006)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Limited
SLC2A1
(HGNC:11005)
myoclonic-astatic epilepsy
(MONDO_0016025)
Moderate
BRCA1
(HGNC:1100)
Fanconi anemia
(MONDO_0019391)
Moderate
SLC2A2
(HGNC:11006)
neonatal diabetes mellitus
(MONDO_0016391)
Moderate
SLC34A1
(HGNC:11019)
primary Fanconi syndrome
(MONDO_0007600)
Strong
BRCA2
(HGNC:1101)
sarcoma
(MONDO_0005089)
Limited
BRCA2
(HGNC:1101)
medulloblastoma
(MONDO_0007959)
Moderate
BRCA2
(HGNC:1101)
Fanconi anemia complementation group D1
(MONDO_0011584)
Strong
BRCA2
(HGNC:1101)
Fanconi anemia
(MONDO_0019391)
Definitive
SLC4A1
(HGNC:11027)
southeast Asian ovalocytosis
(MONDO_0008165)
Definitive
SLC35A2
(HGNC:11022)
SLC35A2-congenital disorder of glycosylation
(MONDO_0010478)
Strong
SLC4A1
(HGNC:11027)
cryohydrocytosis
(MONDO_0008494)
Limited
SLC4A1
(HGNC:11027)
hereditary spherocytosis
(MONDO_0019350)
Definitive
SLC4A3
(HGNC:11029)
short QT syndrome
(MONDO_0000453)
Strong
SLC5A1
(HGNC:11036)
glucose-galactose malabsorption
(MONDO_0011731)
Definitive
SLC6A14
(HGNC:11047)
cystic fibrosis
(MONDO_0009061)
Limited
SLC5A6
(HGNC:11041)
neurodegeneration, infantile-onset, biotin-responsive
(MONDO_0033546)
Strong
SLC5A5
(HGNC:11040)
familial thyroid dyshormonogenesis
(MONDO_0010132)
Definitive
SLC6A4
(HGNC:11050)
autism spectrum disorder
(MONDO_0005258)
Limited
SLC6A2
(HGNC:11048)
postural orthostatic tachycardia syndrome
(MONDO_0011479)
Disputed
SLC6A3
(HGNC:11049)
parkinsonism-dystonia, infantile
(MONDO_0013150)
Definitive
SLC6A9
(HGNC:11056)
atypical glycine encephalopathy
(MONDO_0015010)
Strong
SLC9A1
(HGNC:11071)
Lichtenstein-Knorr syndrome
(MONDO_0014572)
Strong
SLC7A3
(HGNC:11061)
autism spectrum disorder
(MONDO_0005258)
Moderate
SLC9A3
(HGNC:11073)
cystic fibrosis
(MONDO_0009061)
Strong
SLC9A3
(HGNC:11073)
congenital sodium diarrhea
(MONDO_0015170)
Strong
SNAI2
(HGNC:11094)
Waardenburg syndrome
(MONDO_0018094)
Limited
SNAI2
(HGNC:11094)
Waardenburg syndrome type 2
(MONDO_0019517)
Limited
SMARCA1
(HGNC:11097)
neurodevelopmental disorder
(MONDO_0700092)
Strong
SMARCA1
(HGNC:11097)
X-linked intellectual disability
(MONDO_0100284)
Limited
SMARCA4
(HGNC:11100)
rhabdoid tumor predisposition syndrome 2
(MONDO_0013224)
Moderate
SMARCA4
(HGNC:11100)
familial rhabdoid tumor
(MONDO_0016473)
Limited
SMARCA4
(HGNC:11100)
intellectual disability, autosomal dominant 16
(MONDO_0013821)
Moderate
SMARCB1
(HGNC:11103)
schwannomatosis
(MONDO_0008075)
Strong
SMARCA4
(HGNC:11100)
Coffin-Siris syndrome
(MONDO_0015452)
Strong
SMARCB1
(HGNC:11103)
Coffin-Siris syndrome
(MONDO_0015452)
Definitive
SMARCB1
(HGNC:11103)
rhabdoid tumor predisposition syndrome 1
(MONDO_0012252)
Limited
SMARCD2
(HGNC:11107)
specific granule deficiency
(MONDO_0009506)
Moderate
SMARCB1
(HGNC:11103)
familial rhabdoid tumor
(MONDO_0016473)
Strong
SMARCC2
(HGNC:11105)
Coffin-Siris syndrome 8
(MONDO_0032702)
Strong
SMN1
(HGNC:11117)
spinal muscular atrophy, type II
(MONDO_0009673)
Definitive
SMPD1
(HGNC:11120)
acid sphingomyelinase deficiency
(MONDO_0100464)
Definitive
ARID1A
(HGNC:11110)
Coffin-Siris syndrome
(MONDO_0015452)
Strong
SMPX
(HGNC:11122)
hearing loss, X-linked 4
(MONDO_0010238)
Strong
SNCA
(HGNC:11138)
parkinsonian-pyramidal syndrome
(MONDO_0009830)
Limited
SNCA
(HGNC:11138)
Parkinson disease
(MONDO_0005180)
Definitive
SIK1
(HGNC:11142)
early myoclonic encephalopathy
(MONDO_0016022)
Strong
SNCA
(HGNC:11138)
Lewy body dementia
(MONDO_0007488)
Definitive
SIK1
(HGNC:11142)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
SIK1
(HGNC:11142)
West syndrome
(MONDO_0018097)
Strong
SNX3
(HGNC:11174)
MMEP syndrome
(MONDO_0011045)
Disputed
SNTA1
(HGNC:11167)
long QT syndrome
(MONDO_0002442)
Limited
SOD1
(HGNC:11179)
amyotrophic lateral sclerosis type 1
(MONDO_0007103)
Definitive
SOD1
(HGNC:11179)
amyotrophic lateral sclerosis
(MONDO_0004976)
Definitive
BSN
(HGNC:1117)
epilepsy
(MONDO_0005027)
Strong
CAPN15
(HGNC:11182)
oculogastrointestinal-neurodevelopmental syndrome
(MONDO_0036189)
Strong
SOS1
(HGNC:11187)
Costello syndrome
(MONDO_0009026)
Limited
SORD
(HGNC:11184)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Moderate
KDM5C
(HGNC:11114)
syndromic X-linked intellectual disability Claes-Jensen type
(MONDO_0010355)
Definitive
SMO
(HGNC:11119)
congenital hypothalamic hamartoma syndrome
(MONDO_0009436)
Limited
SMO
(HGNC:11119)
Curry-Jones syndrome
(MONDO_0011134)
Strong
SORD
(HGNC:11184)
neuronopathy, distal hereditary motor, autosomal recessive 8
(MONDO_0030055)
Strong
SMN1
(HGNC:11117)
spinal muscular atrophy, type III
(MONDO_0009672)
Strong
SOS1
(HGNC:11187)
hereditary gingival fibromatosis
(MONDO_0016070)
Limited
SMPD1
(HGNC:11120)
Niemann-Pick disease type A
(MONDO_0009756)
Definitive
SOX10
(HGNC:11190)
PCWH syndrome
(MONDO_0012198)
Moderate
SOS1
(HGNC:11187)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Moderate
SMO
(HGNC:11119)
medulloblastoma
(MONDO_0007959)
Limited
SOX11
(HGNC:11191)
intellectual disability, autosomal dominant 27
(MONDO_0014376)
Strong
SOX11
(HGNC:11191)
Coffin-Siris syndrome
(MONDO_0015452)
Definitive
SOX2
(HGNC:11195)
anophthalmia/microphthalmia-esophageal atresia syndrome
(MONDO_0008799)
Definitive
SOX3
(HGNC:11199)
septooptic dysplasia
(MONDO_0008428)
Limited
SOX3
(HGNC:11199)
panhypopituitarism, X-linked
(MONDO_0010712)
Moderate
SOX3
(HGNC:11199)
46,XX ovotesticular disorder of sex development
(MONDO_0016281)
Limited
SOX3
(HGNC:11199)
panhypopituitarism
(MONDO_0019591)
Moderate
SOX4
(HGNC:11200)
atrial fibrillation
(MONDO_0004981)
Limited
SOS2
(HGNC:11188)
Noonan syndrome
(MONDO_0018997)
Strong
SOX10
(HGNC:11190)
Waardenburg syndrome type 4C
(MONDO_0013202)
Limited
SOX4
(HGNC:11200)
Coffin-Siris syndrome
(MONDO_0015452)
Limited
SOX9
(HGNC:11204)
isolated Pierre-Robin syndrome
(MONDO_0009869)
Limited
SOX9
(HGNC:11204)
campomelic dysplasia
(MONDO_0007251)
Definitive
SOX2
(HGNC:11195)
septooptic dysplasia
(MONDO_0008428)
Definitive
SOX9
(HGNC:11204)
46,XY complete gonadal dysgenesis
(MONDO_0010765)
Moderate
SOS1
(HGNC:11187)
Noonan syndrome
(MONDO_0018997)
Definitive
SOX9
(HGNC:11204)
46,XX ovotesticular disorder of sex development
(MONDO_0016281)
Limited
SMARCE1
(HGNC:11109)
Coffin-Siris syndrome
(MONDO_0015452)
Definitive
SPAG1
(HGNC:11212)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
SMPD1
(HGNC:11120)
Niemann-Pick disease
(MONDO_0001982)
Definitive
SPARC
(HGNC:11219)
osteogenesis imperfecta type 4
(MONDO_0008148)
Moderate
SOX10
(HGNC:11190)
deaf blind hypopigmentation syndrome, Yemenite type
(MONDO_0011133)
Limited
SPG11
(HGNC:11226)
juvenile amyotrophic lateral sclerosis
(MONDO_0017593)
Moderate
ATL1
(HGNC:11231)
hereditary sensory and autonomic neuropathy type 1
(MONDO_0018213)
Moderate
SOX10
(HGNC:11190)
Kallmann syndrome
(MONDO_0018800)
Strong
SMPD1
(HGNC:11120)
Niemann-Pick disease type B
(MONDO_0011871)
Definitive
SPG7
(HGNC:11237)
lateral sclerosis
(MONDO_0018155)
Moderate
SOX10
(HGNC:11190)
Waardenburg syndrome type 2
(MONDO_0019517)
Definitive
SPG7
(HGNC:11237)
hereditary spastic paraplegia 7
(MONDO_0011803)
Strong
SPINK1
(HGNC:11244)
tropical pancreatitis
(MONDO_0011986)
Strong
SPINK1
(HGNC:11244)
hereditary chronic pancreatitis
(MONDO_0008185)
Moderate
SPINT2
(HGNC:11247)
syndromic congenital sodium diarrhea
(MONDO_0034204)
Definitive
SPP1
(HGNC:11255)
systemic lupus erythematosus
(MONDO_0007915)
Limited
SPTAN1
(HGNC:11273)
West syndrome
(MONDO_0018097)
Strong
SPTAN1
(HGNC:11273)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
SPTLC2
(HGNC:11278)
neuropathy, hereditary sensory and autonomic, type 1C
(MONDO_0013337)
Strong
SPTLC2
(HGNC:11278)
hereditary sensory and autonomic neuropathy type 1
(MONDO_0018213)
Strong
SQSTM1
(HGNC:11280)
amyotrophic lateral sclerosis
(MONDO_0004976)
Moderate
SQSTM1
(HGNC:11280)
neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset
(MONDO_0014940)
Limited
SRC
(HGNC:11283)
colorectal cancer
(MONDO_0005575)
Limited
SRD5A2
(HGNC:11285)
46,XY disorder of sex development due to 5-alpha-reductase 2 deficiency
(MONDO_0009923)
Definitive
SREBF1
(HGNC:11289)
hereditary mucoepithelial dysplasia
(MONDO_0008017)
Limited
SREBF1
(HGNC:11289)
Hirschsprung disease
(MONDO_0018309)
Limited
SREBF2
(HGNC:11290)
hereditary spastic paraplegia
(MONDO_0019064)
Moderate
SRP54
(HGNC:11301)
Shwachman-Diamond syndrome
(MONDO_0009833)
Strong
SRY
(HGNC:11311)
46,XY complete gonadal dysgenesis
(MONDO_0010765)
Definitive
SRY
(HGNC:11311)
46,XX ovotesticular disorder of sex development
(MONDO_0016281)
Refuted
SRY
(HGNC:11311)
46,XY partial gonadal dysgenesis
(MONDO_0016674)
Limited
SSBP1
(HGNC:11317)
Leigh syndrome
(MONDO_0009723)
Limited
BTK
(HGNC:1133)
Bruton-type agammaglobulinemia
(MONDO_0010421)
Definitive
SSR4
(HGNC:11326)
SSR4-congenital disorder of glycosylation
(MONDO_0010490)
Strong
BTK
(HGNC:1133)
isolated growth hormone deficiency type III
(MONDO_0010615)
Refuted
STAG2
(HGNC:11355)
Mullegama-Klein-Martinez syndrome
(MONDO_0026722)
Limited
ST14
(HGNC:11344)
autosomal recessive congenital ichthyosis 11
(MONDO_0011218)
Moderate
STK11
(HGNC:11389)
familial pancreatic carcinoma
(MONDO_0015278)
Limited
STAT1
(HGNC:11362)
immunodeficiency 31B
(MONDO_0013427)
Moderate
STK11
(HGNC:11389)
familial ovarian cancer
(MONDO_0016248)
Limited
AURKA
(HGNC:11393)
breast cancer
(MONDO_0007254)
Limited
STAT4
(HGNC:11365)
systemic lupus erythematosus
(MONDO_0007915)
Strong
SRPK3
(HGNC:11402)
intellectual disability
(MONDO_0001071)
Strong
BRSK2
(HGNC:11405)
neurodevelopmental disorder
(MONDO_0700092)
Strong
STIM1
(HGNC:11386)
combined immunodeficiency due to STIM1 deficiency
(MONDO_0013008)
Moderate
STK4
(HGNC:11408)
combined immunodeficiency due to STK4 deficiency
(MONDO_0013934)
Strong
CDKL5
(HGNC:11411)
atypical Rett syndrome
(MONDO_0017746)
Definitive
STAT5B
(HGNC:11367)
growth hormone insensitivity syndrome
(MONDO_0015892)
Strong
CDKL5
(HGNC:11411)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
CDKL5
(HGNC:11411)
West syndrome
(MONDO_0018097)
Strong
STS
(HGNC:11425)
recessive X-linked ichthyosis
(MONDO_0010622)
Definitive
STUB1
(HGNC:11427)
autosomal recessive spinocerebellar ataxia 16
(MONDO_0014339)
Strong
STK11
(HGNC:11389)
Peutz-Jeghers syndrome
(MONDO_0008280)
Definitive
STUB1
(HGNC:11427)
spinocerebellar ataxia 48
(MONDO_0032526)
Strong
STX11
(HGNC:11429)
familial hemophagocytic lymphohistiocytosis 4
(MONDO_0011336)
Definitive
STX16
(HGNC:11431)
pseudohypoparathyroidism type 1B
(MONDO_0011301)
Strong
STX1A
(HGNC:11433)
cystic fibrosis
(MONDO_0009061)
Moderate
STXBP1
(HGNC:11444)
intellectual disability
(MONDO_0001071)
Strong
STXBP1
(HGNC:11444)
autism spectrum disorder
(MONDO_0005258)
Limited
STXBP1
(HGNC:11444)
developmental and epileptic encephalopathy, 4
(MONDO_0012812)
Definitive
STXBP1
(HGNC:11444)
West syndrome
(MONDO_0018097)
Strong
STXBP1
(HGNC:11444)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
STXBP2
(HGNC:11445)
microvillus inclusion disease
(MONDO_0009635)
Limited
STXBP2
(HGNC:11445)
familial hemophagocytic lymphohistiocytosis 5
(MONDO_0013135)
Definitive
SUCLA2
(HGNC:11448)
mitochondrial DNA depletion syndrome, encephalomyopathic form with methylmalonic aciduria
(MONDO_0012791)
Strong
SUCLA2
(HGNC:11448)
Leigh syndrome
(MONDO_0009723)
Moderate
SUCLG1
(HGNC:11449)
Leigh syndrome
(MONDO_0009723)
Limited
BUB1
(HGNC:1148)
colorectal cancer
(MONDO_0005575)
Limited
SUCLG1
(HGNC:11449)
mitochondrial DNA depletion syndrome 9
(MONDO_0009504)
Strong
SYNGAP1
(HGNC:11497)
myoclonic-astatic epilepsy
(MONDO_0016025)
Moderate
SYNGAP1
(HGNC:11497)
SYNGAP1-related developmental and epileptic encephalopathy
(MONDO_0034099)
Definitive
SYNGAP1
(HGNC:11497)
intellectual disability, autosomal dominant 5
(MONDO_0012960)
Definitive
SYNGR1
(HGNC:11498)
bipolar disorder
(MONDO_0004985)
Limited
SYNGR1
(HGNC:11498)
schizophrenia
(MONDO_0005090)
Limited
BUB1B
(HGNC:1149)
mosaic variegated aneuploidy syndrome
(MONDO_0000141)
Strong
BUB1B
(HGNC:1149)
rhabdomyosarcoma
(MONDO_0005212)
Limited
BUB1B
(HGNC:1149)
mosaic variegated aneuploidy syndrome 1
(MONDO_0009759)
Definitive
SYNJ1
(HGNC:11503)
young-onset Parkinson disease
(MONDO_0017279)
Strong
SYNJ1
(HGNC:11503)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
SYT1
(HGNC:11509)
infantile hypotonia-oculomotor anomalies-hyperkinetic movements-developmental delay syndrome
(MONDO_0033864)
Strong
TBXT
(HGNC:11515)
chordoma
(MONDO_0008978)
Definitive
TAC3
(HGNC:11521)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
TACR3
(HGNC:11528)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
TACR3
(HGNC:11528)
Kallmann syndrome
(MONDO_0018800)
Limited
EPCAM
(HGNC:11529)
hereditary breast carcinoma
(MONDO_0016419)
Limited
BVES
(HGNC:1152)
tetralogy of fallot
(MONDO_0008542)
Limited
SYNJ1
(HGNC:11503)
early-onset Parkinson disease 20
(MONDO_0014233)
Strong
EPCAM
(HGNC:11529)
congenital diarrhea 5 with tufting enteropathy
(MONDO_0013184)
Definitive
TAF1
(HGNC:11535)
X-linked dystonia-parkinsonism
(MONDO_0010747)
Definitive
TAF6
(HGNC:11540)
Alazami-Yuan syndrome
(MONDO_0014931)
Limited
TAF15
(HGNC:11547)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
BRF1
(HGNC:11551)
cerebellar-facial-dental syndrome
(MONDO_0014529)
Strong
TARDBP
(HGNC:11571)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
TARDBP
(HGNC:11571)
inclusion body myositis
(MONDO_0007827)
Limited
TBC1D1
(HGNC:11578)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Moderate
TBCE
(HGNC:11582)
hypoparathyroidism-retardation-dysmorphism syndrome
(MONDO_0009426)
Definitive
TBCE
(HGNC:11582)
autosomal recessive Kenny-Caffey syndrome
(MONDO_0009486)
Strong
TBK1
(HGNC:11584)
frontotemporal dementia with motor neuron disease
(MONDO_0017161)
Strong
TBP
(HGNC:11588)
spinocerebellar ataxia type 17
(MONDO_0011781)
Definitive
TBX1
(HGNC:11592)
velocardiofacial syndrome
(MONDO_0008644)
Strong
TBX1
(HGNC:11592)
conotruncal heart malformations
(MONDO_0016581)
Moderate
TBX15
(HGNC:11594)
pelviscapular dysplasia
(MONDO_0009845)
Moderate
TBX20
(HGNC:11598)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
TBX4
(HGNC:11603)
coxopodopatellar syndrome
(MONDO_0007841)
Definitive
TBX22
(HGNC:11600)
cleft palate with or without ankyloglossia, X-linked
(MONDO_0010560)
Definitive
TBX4
(HGNC:11603)
heritable pulmonary arterial hypertension
(MONDO_0017148)
Limited
TBX4
(HGNC:11603)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
TBX5
(HGNC:11604)
Holt-Oram syndrome
(MONDO_0007732)
Definitive
TBX6
(HGNC:11605)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Moderate
TBXAS1
(HGNC:11609)
ghosal hematodiaphyseal dysplasia
(MONDO_0009274)
Definitive
TWNK
(HGNC:1160)
autosomal dominant progressive external ophthalmoplegia
(MONDO_0008003)
Strong
TWNK
(HGNC:1160)
mitochondrial DNA depletion syndrome 7 (hepatocerebral type)
(MONDO_0010060)
Strong
TCAP
(HGNC:11610)
dilated cardiomyopathy
(MONDO_0005021)
Limited
TWNK
(HGNC:1160)
Perrault syndrome
(MONDO_0017312)
Definitive
TCAP
(HGNC:11610)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
TCAP
(HGNC:11610)
autosomal recessive limb-girdle muscular dystrophy type 2G
(MONDO_0011170)
Limited
CEP55
(HGNC:1161)
multinucleated neurons-anhydramnios-renal dysplasia-cerebellar hypoplasia-hydranencephaly syndrome
(MONDO_0009359)
Strong
HNF1A
(HGNC:11621)
maturity-onset diabetes of the young type 3
(MONDO_0010894)
Definitive
HNF1A
(HGNC:11621)
monogenic diabetes
(MONDO_0015967)
Definitive
TCF12
(HGNC:11623)
TCF12-related craniosynostosis
(MONDO_0014128)
Definitive
HNF1B
(HGNC:11630)
renal cysts and diabetes syndrome
(MONDO_0007669)
Definitive
TCF12
(HGNC:11623)
Kallmann syndrome
(MONDO_0018800)
Strong
HNF1A
(HGNC:11621)
maturity-onset diabetes of the young
(MONDO_0018911)
Definitive
HNF1B
(HGNC:11630)
unilateral multicystic dysplastic kidney
(MONDO_0019981)
Limited
HNF1B
(HGNC:11630)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Limited
TCF4
(HGNC:11634)
intellectual disability
(MONDO_0001071)
Strong
TCF4
(HGNC:11634)
autism spectrum disorder
(MONDO_0005258)
Moderate
TCF4
(HGNC:11634)
Fuchs' endothelial dystrophy
(MONDO_0005321)
Definitive
TCF4
(HGNC:11634)
Pitt-Hopkins syndrome
(MONDO_0012589)
Definitive
ZEB1
(HGNC:11642)
posterior polymorphous corneal dystrophy 3
(MONDO_0012200)
Strong
ZEB1
(HGNC:11642)
Fuchs' endothelial dystrophy
(MONDO_0005321)
Limited
ZEB1
(HGNC:11642)
posterior polymorphous corneal dystrophy
(MONDO_0020364)
Definitive
TDO2
(HGNC:11708)
familial hypertryptophanemia
(MONDO_0010907)
Limited
TEAD1
(HGNC:11714)
Aicardi syndrome
(MONDO_0010568)
Limited
TECTA
(HGNC:11720)
autosomal recessive nonsyndromic hearing loss 21
(MONDO_0011351)
Strong
TECTA
(HGNC:11720)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Strong
TERT
(HGNC:11730)
dyskeratosis congenita
(MONDO_0015780)
Definitive
TEK
(HGNC:11724)
primary congenital glaucoma
(MONDO_0000365)
Strong
TERT
(HGNC:11730)
Hoyeraal-Hreidarsson syndrome
(MONDO_0018045)
Strong
TERT
(HGNC:11730)
acute myeloid leukemia
(MONDO_0018874)
Strong
TF
(HGNC:11740)
atransferrinemia
(MONDO_0008846)
Definitive
TFAP2B
(HGNC:11743)
Char syndrome
(MONDO_0008209)
Definitive
TFG
(HGNC:11758)
hereditary spastic paraplegia 57
(MONDO_0014295)
Strong
TG
(HGNC:11764)
thyroid cancer
(MONDO_0002108)
Limited
TFR2
(HGNC:11762)
hemochromatosis type 3
(MONDO_0011417)
Strong
TGFB1
(HGNC:11766)
cystic fibrosis
(MONDO_0009061)
Limited
TGFB1
(HGNC:11766)
Camurati-Engelmann disease
(MONDO_0007542)
Definitive
TG
(HGNC:11764)
familial thyroid dyshormonogenesis
(MONDO_0010132)
Definitive
TGFB3
(HGNC:11769)
Rienhoff syndrome
(MONDO_0014262)
Strong
TGFB3
(HGNC:11769)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Refuted
TGFB2
(HGNC:11768)
Loeys-Dietz syndrome 4
(MONDO_0013897)
Strong
TGFB3
(HGNC:11769)
Loeys-Dietz syndrome
(MONDO_0018954)
Moderate
TGFBI
(HGNC:11771)
epithelial basement membrane dystrophy
(MONDO_0007375)
Limited
TGFBI
(HGNC:11771)
granular corneal dystrophy type I
(MONDO_0007377)
Definitive
TGFBI
(HGNC:11771)
lattice corneal dystrophy type I
(MONDO_0007380)
Definitive
TGFBI
(HGNC:11771)
Thiel-Behnke corneal dystrophy
(MONDO_0011185)
Strong
TGFBI
(HGNC:11771)
Reis-Bucklers corneal dystrophy
(MONDO_0012043)
Strong
TGFBI
(HGNC:11771)
granular corneal dystrophy type II
(MONDO_0011855)
Definitive
TGFBR1
(HGNC:11772)
multiple self-healing squamous epithelioma
(MONDO_0007566)
Definitive
TGFBR1
(HGNC:11772)
Loeys-Dietz syndrome 1
(MONDO_0012212)
Definitive
TGFBR2
(HGNC:11773)
Loeys-Dietz syndrome 2
(MONDO_0012427)
Strong
TGFBR1
(HGNC:11772)
Loeys-Dietz syndrome
(MONDO_0018954)
Strong
TGFBR2
(HGNC:11773)
Loeys-Dietz syndrome
(MONDO_0018954)
Definitive
TGM1
(HGNC:11777)
bathing suit ichthyosis
(MONDO_0015085)
Strong
TGM1
(HGNC:11777)
self-healing collodion baby
(MONDO_0017267)
Moderate
TGM1
(HGNC:11777)
acral self-healing collodion baby
(MONDO_0017268)
Limited
TGM1
(HGNC:11777)
congenital non-bullous ichthyosiform erythroderma
(MONDO_0019306)
Definitive
TH
(HGNC:11782)
TH-deficient dopa-responsive dystonia
(MONDO_0011551)
Moderate
THPO
(HGNC:11795)
familial thrombocytosis
(MONDO_0019111)
Strong
THPO
(HGNC:11795)
congenital amegakaryocytic thrombocytopenia
(MONDO_0800451)
Strong
TH
(HGNC:11782)
tyrosine hydroxylase deficiency
(MONDO_0100064)
Definitive
TIA1
(HGNC:11802)
distal myopathy, Welander type
(MONDO_0011466)
Strong
KLF10
(HGNC:11810)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
KLF11
(HGNC:11811)
maturity-onset diabetes of the young type 7
(MONDO_0012513)
Strong
KLF11
(HGNC:11811)
monogenic diabetes
(MONDO_0015967)
Strong
KLF11
(HGNC:11811)
maturity-onset diabetes of the young
(MONDO_0018911)
Limited
TIMM8A
(HGNC:11817)
deafness dystonia syndrome
(MONDO_0010578)
Definitive
MYRF
(HGNC:1181)
encephalitis/encephalopathy, mild, with reversible myelin vacuolization
(MONDO_0020853)
Moderate
MYRF
(HGNC:1181)
cardiac-urogenital syndrome
(MONDO_0032653)
Moderate
TINF2
(HGNC:11824)
pulmonary fibrosis
(MONDO_0002771)
Limited
TINF2
(HGNC:11824)
thyroid gland papillary carcinoma
(MONDO_0005075)
Strong
TINF2
(HGNC:11824)
Revesz syndrome
(MONDO_0009990)
Moderate
TINF2
(HGNC:11824)
Hoyeraal-Hreidarsson syndrome
(MONDO_0018045)
Moderate
NKX2-1
(HGNC:11825)
brain-lung-thyroid syndrome
(MONDO_0012593)
Definitive
NKX2-1
(HGNC:11825)
hereditary progressive chorea without dementia
(MONDO_0021011)
Strong
TK2
(HGNC:11831)
mitochondrial disease
(MONDO_0044970)
Strong
TJP2
(HGNC:11828)
cholestasis, progressive familial intrahepatic, 4
(MONDO_0014381)
Strong
TKT
(HGNC:11834)
transketolase deficiency
(MONDO_0014881)
Strong
TLK2
(HGNC:11842)
intellectual disability, autosomal dominant 57
(MONDO_0054837)
Strong
TMPO
(HGNC:11875)
dilated cardiomyopathy
(MONDO_0005021)
Limited
TNFAIP3
(HGNC:11896)
systemic lupus erythematosus
(MONDO_0007915)
Strong
ACO2
(HGNC:118)
infantile cerebellar-retinal degeneration
(MONDO_0013802)
Definitive
TNFRSF11A
(HGNC:11908)
familial expansile osteolysis
(MONDO_0008275)
Definitive
TNFRSF11A
(HGNC:11908)
dysosteosclerosis
(MONDO_0009138)
Moderate
ACO2
(HGNC:118)
optic atrophy 9
(MONDO_0014571)
Strong
TNFRSF11A
(HGNC:11908)
osteosarcoma
(MONDO_0009807)
Refuted
TNFRSF11A
(HGNC:11908)
autosomal recessive osteopetrosis 7
(MONDO_0012859)
Limited
TNFRSF11B
(HGNC:11909)
juvenile Paget disease
(MONDO_0009394)
Definitive
TNFRSF1A
(HGNC:11916)
autosomal dominant familial periodic fever
(MONDO_0007727)
Definitive
CD40
(HGNC:11919)
hyper-IgM syndrome type 3
(MONDO_0011735)
Strong
FAS
(HGNC:11920)
autoimmune lymphoproliferative syndrome type 1
(MONDO_0011158)
Definitive
TNFSF11
(HGNC:11926)
autosomal recessive osteopetrosis
(MONDO_0019026)
Strong
CD27
(HGNC:11922)
lymphoproliferative syndrome 2
(MONDO_0014054)
Moderate
TNFSF12
(HGNC:11927)
common variable immunodeficiency
(MONDO_0015517)
Limited
TNFSF4
(HGNC:11934)
systemic lupus erythematosus
(MONDO_0007915)
Strong
TNFSF13
(HGNC:11928)
common variable immunodeficiency
(MONDO_0015517)
Limited
FASLG
(HGNC:11936)
autoimmune lymphoproliferative syndrome type 1
(MONDO_0011158)
Limited
TNNC1
(HGNC:11943)
dilated cardiomyopathy
(MONDO_0005021)
Strong
TNNC1
(HGNC:11943)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
TNNC1
(HGNC:11943)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
TNNI2
(HGNC:11946)
Sheldon-hall syndrome
(MONDO_0011128)
Strong
TNNI3
(HGNC:11947)
dilated cardiomyopathy
(MONDO_0005021)
Limited
TNNI3
(HGNC:11947)
dilated cardiomyopathy 2A
(MONDO_0012746)
Limited
TNNI3
(HGNC:11947)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
TNNT1
(HGNC:11948)
nemaline myopathy 5
(MONDO_0011539)
Moderate
TNNT2
(HGNC:11949)
cardiomyopathy
(MONDO_0004994)
Strong
TNNT2
(HGNC:11949)
dilated cardiomyopathy
(MONDO_0005021)
Definitive
TNNT2
(HGNC:11949)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
TNNT2
(HGNC:11949)
hypertrophic cardiomyopathy
(MONDO_0005045)
Definitive
CD70
(HGNC:11937)
severe combined immunodeficiency due to CD70 deficiency
(MONDO_0034054)
Limited
TNNT3
(HGNC:11950)
Sheldon-hall syndrome
(MONDO_0011128)
Strong
TNNT2
(HGNC:11949)
left ventricular noncompaction
(MONDO_0018901)
Limited
TNNT3
(HGNC:11950)
nemaline myopathy
(MONDO_0018958)
Moderate
MED12
(HGNC:11957)
blepharophimosis - intellectual disability syndrome, MKB type
(MONDO_0010477)
Moderate
EP400
(HGNC:11958)
neurodevelopmental disorder
(MONDO_0700092)
Strong
MED12
(HGNC:11957)
X-linked intellectual disability with marfanoid habitus
(MONDO_0010655)
Strong
CNPY3
(HGNC:11968)
West syndrome
(MONDO_0018097)
Moderate
TOP2B
(HGNC:11990)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
TOP2B
(HGNC:11990)
B-cell immunodeficiency, distal limb anomalies, and urogenital malformations
(MONDO_0012243)
Strong
TP53
(HGNC:11998)
sarcoma
(MONDO_0005089)
Definitive
TP53
(HGNC:11998)
colorectal cancer
(MONDO_0005575)
Definitive
TP53
(HGNC:11998)
breast cancer
(MONDO_0007254)
Definitive
TP53
(HGNC:11998)
choroid plexus carcinoma
(MONDO_0016718)
Definitive
MED12
(HGNC:11957)
cholestasis-pigmentary retinopathy-cleft palate syndrome
(MONDO_0012997)
Strong
TP53
(HGNC:11998)
Li-Fraumeni syndrome
(MONDO_0018875)
Definitive
ACOX1
(HGNC:119)
peroxisomal acyl-CoA oxidase deficiency
(MONDO_0009919)
Definitive
ACOX1
(HGNC:119)
Mitchell syndrome
(MONDO_0030073)
Moderate
TPI1
(HGNC:12009)
triosephosphate isomerase deficiency
(MONDO_0014221)
Definitive
TPM1
(HGNC:12010)
left ventricular noncompaction
(MONDO_0018901)
Strong
TPM1
(HGNC:12010)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
TPM2
(HGNC:12011)
arthrogryposis, distal, type 1A
(MONDO_0007157)
Limited
TPM2
(HGNC:12011)
congenital fiber-type disproportion myopathy
(MONDO_0009711)
Strong
TPM2
(HGNC:12011)
congenital myopathy
(MONDO_0019952)
Strong
TPM2
(HGNC:12011)
Sheldon-hall syndrome
(MONDO_0011128)
Strong
TPM3
(HGNC:12012)
congenital fiber-type disproportion myopathy
(MONDO_0009711)
Definitive
TPM2
(HGNC:12011)
cap myopathy
(MONDO_0015753)
Strong
TRDN
(HGNC:12261)
long QT syndrome
(MONDO_0002442)
Strong
TRDN
(HGNC:12261)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Strong
TREX1
(HGNC:12269)
systemic lupus erythematosus
(MONDO_0007915)
Strong
TREX1
(HGNC:12269)
retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
(MONDO_0008641)
Strong
TREX1
(HGNC:12269)
familial chilblain lupus
(MONDO_0018827)
Definitive
TREX1
(HGNC:12269)
Aicardi-Goutieres syndrome 1
(MONDO_0009165)
Definitive
TREX1
(HGNC:12269)
Aicardi-Goutieres syndrome
(MONDO_0018866)
Definitive
GIPC1
(HGNC:1226)
oculopharyngodistal myopathy
(MONDO_0025193)
Strong
SERPING1
(HGNC:1228)
hereditary angioedema type 1
(MONDO_0015053)
Definitive
SERPING1
(HGNC:1228)
C1 inhibitor deficiency
(MONDO_0007361)
Definitive
TRIP11
(HGNC:12305)
achondrogenesis type IA
(MONDO_0008701)
Strong
TRIP12
(HGNC:12306)
Clark-Baraitser syndrome
(MONDO_0030914)
Definitive
ZNHIT3
(HGNC:12309)
PEHO syndrome
(MONDO_0009841)
Strong
TRPS1
(HGNC:12340)
trichorhinophalangeal syndrome, type III
(MONDO_0008597)
Limited
TSC1
(HGNC:12362)
lung lymphangioleiomyomatosis
(MONDO_0006277)
Limited
TSC1
(HGNC:12362)
tuberous sclerosis
(MONDO_0001734)
Strong
TSFM
(HGNC:12367)
Leigh syndrome
(MONDO_0009723)
Strong
TSC2
(HGNC:12363)
lymphangioleiomyomatosis
(MONDO_0011705)
Strong
RSPH1
(HGNC:12371)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
TSHR
(HGNC:12373)
familial hyperthyroidism due to mutations in TSH receptor
(MONDO_0012203)
Strong
TSHB
(HGNC:12372)
isolated thyroid-stimulating hormone deficiency
(MONDO_0010139)
Limited
TSPYL1
(HGNC:12382)
sudden infant death-dysgenesis of the testes syndrome
(MONDO_0012124)
Strong
TSHR
(HGNC:12373)
athyreosis
(MONDO_0019855)
Limited
TSHR
(HGNC:12373)
thyroid hypoplasia
(MONDO_0019861)
Limited
TTN
(HGNC:12403)
tibial muscular dystrophy
(MONDO_0010870)
Definitive
TUB
(HGNC:12406)
essential tremor
(MONDO_0003233)
Moderate
TUB
(HGNC:12406)
retinitis pigmentosa
(MONDO_0019200)
Limited
TUBB2A
(HGNC:12412)
complex cortical dysplasia with other brain malformations 5
(MONDO_0014337)
Limited
TUBG1
(HGNC:12417)
lissencephaly spectrum disorders
(MONDO_0018838)
Moderate
C1QA
(HGNC:1241)
C1Q deficiency
(MONDO_0013343)
Strong
TUFM
(HGNC:12420)
combined oxidative phosphorylation defect type 4
(MONDO_0012534)
Moderate
TULP1
(HGNC:12423)
Leber congenital amaurosis
(MONDO_0018998)
Strong
MYOT
(HGNC:12399)
myofibrillar myopathy 3
(MONDO_0012215)
Moderate
TULP1
(HGNC:12423)
retinitis pigmentosa
(MONDO_0019200)
Strong
DNAJC7
(HGNC:12392)
amyotrophic lateral sclerosis
(MONDO_0004976)
Moderate
TTN
(HGNC:12403)
dilated cardiomyopathy
(MONDO_0005021)
Definitive
TTN
(HGNC:12403)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
TTN
(HGNC:12403)
early-onset myopathy with fatal cardiomyopathy
(MONDO_0012714)
Limited
TULP3
(HGNC:12425)
ciliopathy
(MONDO_0005308)
Strong
TWIST1
(HGNC:12428)
Sweeney-Cox syndrome
(MONDO_0060592)
Moderate
TULP3
(HGNC:12425)
hepatorenocardiac degenerative fibrosis
(MONDO_0859254)
Limited
C1QBP
(HGNC:1243)
combined oxidative phosphorylation deficiency 33
(MONDO_0054677)
Limited
C1QBP
(HGNC:1243)
mitochondrial disease
(MONDO_0044970)
Limited
TTN
(HGNC:12403)
congenital myopathy
(MONDO_0019952)
Moderate
C1QB
(HGNC:1242)
C1Q deficiency
(MONDO_0013343)
Strong
TYK2
(HGNC:12440)
immunodeficiency 35
(MONDO_0012682)
Strong
TTN
(HGNC:12403)
myopathy, myofibrillar, 9, with early respiratory failure
(MONDO_0011362)
Strong
TYR
(HGNC:12442)
oculocutaneous albinism type 1A
(MONDO_0008745)
Definitive
TTN
(HGNC:12403)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Strong
TTR
(HGNC:12405)
familial amyloid neuropathy
(MONDO_0007100)
Definitive
TTN
(HGNC:12403)
autosomal recessive limb-girdle muscular dystrophy type 2J
(MONDO_0012127)
Strong
TYR
(HGNC:12442)
oculocutaneous albinism type 1B
(MONDO_0011749)
Definitive
TTR
(HGNC:12405)
amyloidosis, hereditary systemic 1
(MONDO_0971004)
Definitive
TYR
(HGNC:12442)
oculocutaneous albinism type 1
(MONDO_0018135)
Definitive
TYROBP
(HGNC:12449)
polycystic lipomembranous osteodysplasia with sclerosing leukoencephaly
(MONDO_0009092)
Strong
TYRP1
(HGNC:12450)
oculocutaneous albinism type 3
(MONDO_0008747)
Limited
C1QC
(HGNC:1245)
C1Q deficiency
(MONDO_0013343)
Strong
C1S
(HGNC:1247)
complement component C1s deficiency
(MONDO_0013419)
Moderate
UBAP1
(HGNC:12461)
spastic paraplegia 80, autosomal dominant
(MONDO_0032737)
Strong
UBA1
(HGNC:12469)
infantile-onset X-linked spinal muscular atrophy
(MONDO_0010532)
Strong
C2
(HGNC:1248)
complement component 2 deficiency
(MONDO_0009006)
Strong
UBQLN1
(HGNC:12508)
intellectual disability
(MONDO_0001071)
Limited
UBQLN2
(HGNC:12509)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
UMOD
(HGNC:12559)
familial juvenile hyperuricemic nephropathy type 1
(MONDO_0008073)
Definitive
C1S
(HGNC:1247)
Ehlers-Danlos syndrome, periodontitis type
(MONDO_0007527)
Moderate
UBE2L3
(HGNC:12488)
systemic lupus erythematosus
(MONDO_0007915)
Strong
UMPS
(HGNC:12563)
orotic aciduria
(MONDO_0009797)
Definitive
UMOD
(HGNC:12559)
autosomal dominant medullary cystic kidney disease with or without hyperuricemia
(MONDO_0008264)
Definitive
UPK3A
(HGNC:12580)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Limited
UQCRB
(HGNC:12582)
mitochondrial complex III deficiency
(MONDO_0015448)
Limited
UQCRC2
(HGNC:12586)
mitochondrial complex III deficiency
(MONDO_0015448)
Strong
UQCRC2
(HGNC:12586)
mitochondrial disease
(MONDO_0044970)
Moderate
UROD
(HGNC:12591)
familial porphyria cutanea tarda
(MONDO_0008296)
Definitive
UQCRFS1
(HGNC:12587)
mitochondrial complex III deficiency
(MONDO_0015448)
Moderate
USH1C
(HGNC:12597)
Usher syndrome type 1
(MONDO_0010168)
Strong
USH1C
(HGNC:12597)
Usher syndrome type 1C
(MONDO_0010171)
Moderate
USH1C
(HGNC:12597)
autosomal recessive nonsyndromic hearing loss 18A
(MONDO_0011192)
Limited
USH2A
(HGNC:12601)
Usher syndrome type 2A
(MONDO_0010169)
Definitive
USH2A
(HGNC:12601)
retinitis pigmentosa
(MONDO_0019200)
Definitive
USH2A
(HGNC:12601)
Usher syndrome type 2
(MONDO_0016484)
Definitive
CLRN1
(HGNC:12605)
retinitis pigmentosa
(MONDO_0019200)
Moderate
CLRN1
(HGNC:12605)
Usher syndrome type 3
(MONDO_0016485)
Strong
CFAP410
(HGNC:1260)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
CFAP410
(HGNC:1260)
axial spondylometaphyseal dysplasia
(MONDO_0011211)
Strong
CFAP410
(HGNC:1260)
cone-rod dystrophy
(MONDO_0015993)
Strong
USP18
(HGNC:12616)
pseudo-TORCH syndrome 2
(MONDO_0018828)
Strong
USP8
(HGNC:12631)
hereditary spastic paraplegia
(MONDO_0019064)
Limited
USP7
(HGNC:12630)
Hao-Fountain syndrome
(MONDO_0014805)
Strong
USP9X
(HGNC:12632)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Moderate
KDM6A
(HGNC:12637)
Kabuki syndrome 2
(MONDO_0010465)
Definitive
KDM6A
(HGNC:12637)
Kabuki syndrome
(MONDO_0016512)
Definitive
VAPB
(HGNC:12649)
amyotrophic lateral sclerosis type 8
(MONDO_0012077)
Definitive
VAPB
(HGNC:12649)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
VARS1
(HGNC:12651)
neurodevelopmental disorder with microcephaly, seizures, and cortical atrophy
(MONDO_0060621)
Moderate
VARS1
(HGNC:12651)
combined oxidative phosphorylation defect type 20
(MONDO_0014397)
Strong
VCL
(HGNC:12665)
dilated cardiomyopathy
(MONDO_0005021)
Strong
VCL
(HGNC:12665)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
VCP
(HGNC:12666)
inclusion body myopathy with Paget disease of bone and frontotemporal dementia
(MONDO_0000507)
Definitive
VCP
(HGNC:12666)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
VCP
(HGNC:12666)
neurodevelopmental disorder
(MONDO_0700092)
Limited
VCP
(HGNC:12666)
inclusion body myopathy with Paget disease of bone and frontotemporal dementia type 1
(MONDO_0008178)
Definitive
VDR
(HGNC:12679)
vitamin D-dependent rickets, type 2
(MONDO_0019642)
Definitive
VHL
(HGNC:12687)
pheochromocytoma
(MONDO_0008233)
Definitive
VHL
(HGNC:12687)
renal cell carcinoma
(MONDO_0005086)
Definitive
VHL
(HGNC:12687)
von Hippel-Lindau disease
(MONDO_0008667)
Definitive
VLDLR
(HGNC:12698)
cerebellar ataxia, intellectual disability, and dysequilibrium
(MONDO_0009133)
Strong
BEST1
(HGNC:12703)
nanophthalmia
(MONDO_0005514)
Moderate
VLDLR
(HGNC:12698)
cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 1
(MONDO_0024542)
Moderate
VHL
(HGNC:12687)
Chuvash polycythemia
(MONDO_0009892)
Definitive
BEST1
(HGNC:12703)
vitelliform macular dystrophy 2
(MONDO_0007931)
Strong
BEST1
(HGNC:12703)
adult-onset foveomacular vitelliform dystrophy
(MONDO_0011979)
Limited
BEST1
(HGNC:12703)
autosomal dominant vitreoretinochoroidopathy
(MONDO_0008662)
Strong
BEST1
(HGNC:12703)
autosomal recessive bestrophinopathy
(MONDO_0012733)
Strong
BEST1
(HGNC:12703)
inherited retinal dystrophy
(MONDO_0019118)
Definitive
BEST1
(HGNC:12703)
retinitis pigmentosa
(MONDO_0019200)
Limited
VPS33B
(HGNC:12712)
arthrogryposis, renal dysfunction, and cholestasis 1
(MONDO_0008822)
Definitive
VRK1
(HGNC:12718)
pontocerebellar hypoplasia type 1
(MONDO_0016396)
Moderate
VSX1
(HGNC:12723)
posterior polymorphous corneal dystrophy
(MONDO_0020364)
Disputed
VWF
(HGNC:12726)
von Willebrand disease 1
(MONDO_0008668)
Definitive
VWF
(HGNC:12726)
von Willebrand disease 3
(MONDO_0010191)
Strong
BEST1
(HGNC:12703)
retinitis pigmentosa 50
(MONDO_0013175)
Strong
VWF
(HGNC:12726)
von Willebrand disease 2
(MONDO_0013304)
Definitive
VWF
(HGNC:12726)
von Willebrand disease type 2A
(MONDO_0015628)
Definitive
VWF
(HGNC:12726)
von Willebrand disease type 2B
(MONDO_0015629)
Definitive
VWF
(HGNC:12726)
von Willebrand disease type 2M
(MONDO_0015630)
Definitive
VWF
(HGNC:12726)
von Willebrand disease type 2N
(MONDO_0015631)
Strong
WARS1
(HGNC:12729)
distal hereditary motor neuropathy
(MONDO_0018894)
Strong
WARS2
(HGNC:12730)
mitochondrial disease
(MONDO_0044970)
Strong
WARS2
(HGNC:12730)
neurodevelopmental disorder, mitochondrial, with abnormal movements and lactic acidosis, with or without seizures
(MONDO_0060578)
Limited
WAS
(HGNC:12731)
Wiskott-Aldrich syndrome
(MONDO_0010518)
Definitive
WAS
(HGNC:12731)
thrombocytopenia 1
(MONDO_0010743)
Definitive
WIPF1
(HGNC:12736)
Wiskott-Aldrich syndrome
(MONDO_0010518)
Limited
WDR4
(HGNC:12756)
Galloway-Mowat syndrome
(MONDO_0009627)
Limited
WASF1
(HGNC:12732)
neurodevelopmental disorder with absent language and variable seizures
(MONDO_0032876)
Definitive
BRWD1
(HGNC:12760)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
WFS1
(HGNC:12762)
type 2 diabetes mellitus
(MONDO_0005148)
Strong
WFS1
(HGNC:12762)
Wolfram syndrome 1
(MONDO_0009101)
Strong
WFS1
(HGNC:12762)
Wolfram-like syndrome
(MONDO_0013673)
Strong
FOXN1
(HGNC:12765)
T-cell immunodeficiency, congenital alopecia, and nail dystrophy
(MONDO_0011132)
Moderate
WFS1
(HGNC:12762)
Wolfram syndrome
(MONDO_0018105)
Definitive
NSD2
(HGNC:12766)
Rauch-Steindl syndrome
(MONDO_0859219)
Limited
WNT1
(HGNC:12774)
osteogenesis imperfecta type 15
(MONDO_0014086)
Definitive
WNT10B
(HGNC:12775)
tooth agenesis
(MONDO_0005486)
Moderate
WNT10B
(HGNC:12775)
split hand-foot malformation 6
(MONDO_0009157)
Moderate
WNT5A
(HGNC:12784)
autosomal dominant Robinow syndrome
(MONDO_0008389)
Strong
WNT7A
(HGNC:12786)
phocomelia, Schinzel type
(MONDO_0010164)
Limited
WNT7A
(HGNC:12786)
Fuhrmann syndrome
(MONDO_0009232)
Moderate
WRN
(HGNC:12791)
osteosarcoma
(MONDO_0009807)
Moderate
WRN
(HGNC:12791)
Werner syndrome
(MONDO_0010196)
Definitive
WT1
(HGNC:12796)
Frasier syndrome
(MONDO_0007635)
Definitive
WWOX
(HGNC:12799)
autosomal recessive spinocerebellar ataxia 12
(MONDO_0013687)
Strong
WT1
(HGNC:12796)
Denys-Drash syndrome
(MONDO_0008682)
Definitive
WWOX
(HGNC:12799)
developmental and epileptic encephalopathy, 28
(MONDO_0014533)
Definitive
WWOX
(HGNC:12799)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
XPA
(HGNC:12814)
xeroderma pigmentosum group A
(MONDO_0010210)
Definitive
XPA
(HGNC:12814)
xeroderma pigmentosum
(MONDO_0019600)
Strong
XPC
(HGNC:12816)
xeroderma pigmentosum group C
(MONDO_0010211)
Strong
XRCC2
(HGNC:12829)
breast cancer
(MONDO_0007254)
Limited
XRCC1
(HGNC:12828)
head and neck cancer
(MONDO_0005627)
Limited
XPC
(HGNC:12816)
xeroderma pigmentosum
(MONDO_0019600)
Definitive
YARS1
(HGNC:12840)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Moderate
YY1
(HGNC:12856)
Gabriele de Vries syndrome
(MONDO_0044738)
Strong
XRCC2
(HGNC:12829)
Fanconi anemia
(MONDO_0019391)
Limited
YWHAG
(HGNC:12852)
developmental and epileptic encephalopathy, 56
(MONDO_0033365)
Strong
ZIC1
(HGNC:12872)
Dandy-Walker syndrome
(MONDO_0009072)
Limited
ZMPSTE24
(HGNC:12877)
Hutchinson-Gilford progeria syndrome
(MONDO_0008310)
Moderate
ZMPSTE24
(HGNC:12877)
mandibuloacral dysplasia with type B lipodystrophy
(MONDO_0012074)
Definitive
ZIC2
(HGNC:12873)
holoprosencephaly
(MONDO_0016296)
Definitive
RNF113A
(HGNC:12974)
trichothiodystrophy
(MONDO_0018053)
Strong
ZMYM2
(HGNC:12989)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Strong
PCGF2
(HGNC:12929)
turnpenny-fry syndrome
(MONDO_0032707)
Definitive
ZMYM2
(HGNC:12989)
neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities
(MONDO_0859190)
Limited
ACTA1
(HGNC:129)
nemaline myopathy 3
(MONDO_0008070)
Strong
ACTA1
(HGNC:129)
congenital fiber-type disproportion myopathy
(MONDO_0009711)
Moderate
ACTA1
(HGNC:129)
zebra body myopathy
(MONDO_0019949)
Limited
ZNF219
(HGNC:13011)
microphthalmia
(MONDO_0021129)
Limited
CBY1
(HGNC:1307)
Joubert syndrome
(MONDO_0018772)
Moderate
SCAPER
(HGNC:13081)
retinitis pigmentosa
(MONDO_0019200)
Strong
C3
(HGNC:1318)
complement component 3 deficiency
(MONDO_0013417)
Strong
ZNF81
(HGNC:13156)
X-linked intellectual disability
(MONDO_0100284)
Disputed
AICDA
(HGNC:13203)
hyper-IgM syndrome type 2
(MONDO_0011528)
Definitive
ARL6
(HGNC:13210)
Bardet-Biedl syndrome
(MONDO_0015229)
Definitive
C3
(HGNC:1318)
C3 glomerulonephritis
(MONDO_0013892)
Moderate
ARL6
(HGNC:13210)
Bardet-Biedl syndrome 3
(MONDO_0010832)
Moderate
BCL11B
(HGNC:13222)
intellectual developmental disorder with speech delay, dysmorphic facies, and t-cell abnormalities
(MONDO_0060763)
Strong
ADAMTS9
(HGNC:13202)
ciliopathy
(MONDO_0005308)
Moderate
BCL11A
(HGNC:13221)
Dias-Logan syndrome
(MONDO_0014914)
Strong
TIMMDC1
(HGNC:1321)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
C4A
(HGNC:1323)
systemic lupus erythematosus
(MONDO_0007915)
Strong
TIMMDC1
(HGNC:1321)
Leigh syndrome
(MONDO_0009723)
Moderate
LMBR1
(HGNC:13243)
triphalangeal thumb-polysyndactyly syndrome
(MONDO_0017454)
Strong
DUOX2
(HGNC:13273)
familial thyroid dyshormonogenesis
(MONDO_0010132)
Definitive
ACTB
(HGNC:132)
Baraitser-Winter syndrome 1
(MONDO_0009470)
Strong
HDAC8
(HGNC:13315)
Cornelia de Lange syndrome 5
(MONDO_0010471)
Definitive
MYOZ2
(HGNC:1330)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
C5
(HGNC:1331)
complement component 5 deficiency
(MONDO_0012295)
Strong
MCOLN1
(HGNC:13356)
Lisch epithelial corneal dystrophy
(MONDO_0010425)
Strong
KDM3B
(HGNC:1337)
Diets-Jongmans syndrome
(MONDO_0030012)
Limited
NEK8
(HGNC:13387)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Strong
NSDHL
(HGNC:13398)
CK syndrome
(MONDO_0010441)
Strong
NEK8
(HGNC:13387)
renal-hepatic-pancreatic dysplasia 2
(MONDO_0014174)
Limited
RLIM
(HGNC:13429)
intellectual disability, X-linked 61
(MONDO_0010506)
Definitive
RPGRIP1
(HGNC:13436)
Leber congenital amaurosis 6
(MONDO_0013446)
Definitive
RPGRIP1
(HGNC:13436)
cone-rod dystrophy
(MONDO_0015993)
Strong
RPGRIP1
(HGNC:13436)
Leber congenital amaurosis
(MONDO_0018998)
Definitive
TRAF3IP2
(HGNC:1343)
chronic mucocutaneous candidiasis
(MONDO_0015279)
Moderate
SLC2A10
(HGNC:13444)
arterial tortuosity syndrome
(MONDO_0008818)
Definitive
SLC2A9
(HGNC:13446)
hereditary renal hypouricemia
(MONDO_0009071)
Definitive
C7
(HGNC:1346)
complement component 7 deficiency
(MONDO_0012412)
Definitive
SLC2A9
(HGNC:13446)
hypouricemia, renal, 2
(MONDO_0012793)
Definitive
USP27X
(HGNC:13486)
X-linked intellectual disability
(MONDO_0100284)
Strong
VPS35
(HGNC:13487)
Parkinson disease 17
(MONDO_0013625)
Definitive
SAMD9
(HGNC:1348)
normophosphatemic familial tumoral calcinosis
(MONDO_0012502)
Strong
ZBTB20
(HGNC:13503)
Primrose syndrome
(MONDO_0009798)
Definitive
RXYLT1
(HGNC:13530)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Moderate
ATP8A2
(HGNC:13533)
cerebellar ataxia, intellectual disability, and dysequilibrium
(MONDO_0009133)
Definitive
ATP8A2
(HGNC:13533)
cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 4
(MONDO_0014104)
Definitive
MARK4
(HGNC:13538)
neurodevelopmental disorder
(MONDO_0700092)
Limited
ERLIN2
(HGNC:1356)
hereditary spastic paraplegia 18
(MONDO_0012639)
Strong
BRD4
(HGNC:13575)
Cornelia de Lange syndrome
(MONDO_0016033)
Limited
C9
(HGNC:1358)
complement component 9 deficiency
(MONDO_0013445)
Definitive
C8B
(HGNC:1353)
type II complement component 8 deficiency
(MONDO_0013421)
Strong
FBXW11
(HGNC:13607)
neurodevelopmental, jaw, eye, and digital syndrome
(MONDO_0030057)
Strong
ADAMTS13
(HGNC:1366)
congenital thrombotic thrombocytopenic purpura
(MONDO_0010122)
Definitive
FBXO11
(HGNC:13590)
intellectual developmental disorder with dysmorphic facies and behavioral abnormalities
(MONDO_0060760)
Strong
KLF13
(HGNC:13672)
congenital heart disease
(MONDO_0005453)
Strong
CTCF
(HGNC:13723)
intellectual disability-feeding difficulties-developmental delay-microcephaly syndrome
(MONDO_0014213)
Strong
DCHS1
(HGNC:13681)
van Maldergem syndrome
(MONDO_0017813)
Limited
KMT2C
(HGNC:13726)
Kleefstra syndrome 2
(MONDO_0054701)
Strong
CDH23
(HGNC:13733)
Usher syndrome type 1
(MONDO_0010168)
Strong
CDH23
(HGNC:13733)
Usher syndrome type 1D
(MONDO_0010984)
Definitive
CDH23
(HGNC:13733)
autosomal recessive nonsyndromic hearing loss 12
(MONDO_0011067)
Strong
ALOXE3
(HGNC:13743)
self-healing collodion baby
(MONDO_0017267)
Strong
ALOXE3
(HGNC:13743)
congenital non-bullous ichthyosiform erythroderma
(MONDO_0019306)
Strong
ALOXE3
(HGNC:13743)
lamellar ichthyosis
(MONDO_0017778)
Strong
SOST
(HGNC:13771)
craniodiaphyseal dysplasia
(MONDO_0009031)
Strong
SOST
(HGNC:13771)
hyperostosis corticalis generalisata
(MONDO_0009395)
Definitive
CA5A
(HGNC:1377)
hyperammonemic encephalopathy due to carbonic anhydrase VA deficiency
(MONDO_0014332)
Strong
PRX
(HGNC:13797)
Charcot-Marie-Tooth disease type 3
(MONDO_0007790)
Strong
NEUROG3
(HGNC:13806)
congenital malabsorptive diarrhea 4
(MONDO_0012479)
Definitive
WNT10A
(HGNC:13829)
tooth agenesis
(MONDO_0005486)
Definitive
SLC12A5
(HGNC:13818)
epilepsy of infancy with migrating focal seizures
(MONDO_0100025)
Moderate
WNT10A
(HGNC:13829)
odonto-onycho-dermal dysplasia
(MONDO_0009773)
Definitive
CA8
(HGNC:1382)
cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 3
(MONDO_0013188)
Strong
ADGRG6
(HGNC:13841)
intellectual disability
(MONDO_0001071)
Limited
LOXL3
(HGNC:13869)
Stickler syndrome
(MONDO_0019354)
Limited
CABP4
(HGNC:1386)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Moderate
FOXP2
(HGNC:13875)
childhood apraxia of speech
(MONDO_0011184)
Definitive
CACNA1A Gene
(HGNC:1388)
episodic ataxia type 2
(MONDO_0007163)
Definitive
CACNA1A Gene
(HGNC:1388)
developmental and epileptic encephalopathy, 42
(MONDO_0014917)
Limited
CACNA1A Gene
(HGNC:1388)
benign paroxysmal torticollis of infancy
(MONDO_0019113)
Limited
CACNA1A Gene
(HGNC:1388)
spinocerebellar ataxia type 6
(MONDO_0008457)
Strong
CACNA1A Gene
(HGNC:1388)
migraine, familial hemiplegic, 1
(MONDO_0020756)
Definitive
ITCH
(HGNC:13890)
syndromic multisystem autoimmune disease due to ITCH deficiency
(MONDO_0013245)
Strong
ATOH7
(HGNC:13907)
persistent hyperplastic primary vitreous
(MONDO_0019631)
Moderate
CACNA1C
(HGNC:1390)
short QT syndrome
(MONDO_0000453)
Moderate
CACNA1C
(HGNC:1390)
intellectual disability
(MONDO_0001071)
Moderate
CACNA1C
(HGNC:1390)
long QT syndrome
(MONDO_0002442)
Strong
CACNA1C
(HGNC:1390)
Timothy syndrome
(MONDO_0010979)
Definitive
CACNA1E
(HGNC:1392)
neurodevelopmental disorder
(MONDO_0700092)
Strong
CACNA1C
(HGNC:1390)
Brugada syndrome
(MONDO_0015263)
Strong
MPIG6B
(HGNC:13937)
thrombocytopenia, anemia, and myelofibrosis
(MONDO_0044316)
Strong
CACNA1F
(HGNC:1393)
congenital stationary night blindness 2A
(MONDO_0010241)
Strong
CACNA1F
(HGNC:1393)
X-linked cone-rod dystrophy 3
(MONDO_0010335)
Limited
CACNA1F
(HGNC:1393)
Aland island eye disease
(MONDO_0010371)
Strong
CACNA1F
(HGNC:1393)
cone-rod dystrophy
(MONDO_0015993)
Moderate
CACNA1F
(HGNC:1393)
inherited retinal dystrophy
(MONDO_0019118)
Strong
CACNA1G
(HGNC:1394)
intellectual disability
(MONDO_0001071)
Limited
CACNA1G
(HGNC:1394)
spinocerebellar ataxia type 42
(MONDO_0014776)
Strong
CACNA1G
(HGNC:1394)
spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits
(MONDO_0060758)
Strong
CACNA1G
(HGNC:1394)
neurodevelopmental disorder
(MONDO_0700092)
Strong
CACNA1H
(HGNC:1395)
childhood absence epilepsy
(MONDO_0010826)
Moderate
CACNA1H
(HGNC:1395)
hyperaldosteronism, familial, type IV
(MONDO_0014875)
Moderate
CACNA1S
(HGNC:1397)
hypokalemic periodic paralysis
(MONDO_0008223)
Definitive
CACNA1S
(HGNC:1397)
malignant hyperthermia, susceptibility to, 5
(MONDO_0011163)
Strong
CACNA1S
(HGNC:1397)
congenital myopathy
(MONDO_0019952)
Limited
CACNA1S
(HGNC:1397)
hypokalemic periodic paralysis, type 1
(MONDO_0042979)
Definitive
CACNA1S
(HGNC:1397)
congenital myopathy 18
(MONDO_0859514)
Limited
PRDM12
(HGNC:13997)
congenital insensitivity to pain-hypohidrosis syndrome
(MONDO_0014662)
Limited
PRDM12
(HGNC:13997)
hereditary sensory and autonomic neuropathy
(MONDO_0015364)
Moderate
CACNA2D1
(HGNC:1399)
short QT syndrome
(MONDO_0000453)
Limited
CACNA2D1
(HGNC:1399)
Brugada syndrome
(MONDO_0015263)
Disputed
PRDM16
(HGNC:14000)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
CACNA2D1
(HGNC:1399)
developmental and epileptic encephalopathy
(MONDO_0100062)
Limited
PRDM16
(HGNC:14000)
left ventricular noncompaction
(MONDO_0018901)
Strong
ANO3
(HGNC:14004)
dystonia 24
(MONDO_0014019)
Strong
TRPV6
(HGNC:14006)
pancreatitis
(MONDO_0004982)
Strong
TRPV6
(HGNC:14006)
hyperparathyroidism, transient neonatal
(MONDO_0032591)
Limited
SLC5A7
(HGNC:14025)
congenital myasthenic syndrome 20
(MONDO_0014939)
Strong
SLC5A7
(HGNC:14025)
distal hereditary motor neuropathy type 7
(MONDO_0015355)
Strong
CSMD1
(HGNC:14026)
autism spectrum disorder
(MONDO_0005258)
Limited
CACNB2
(HGNC:1402)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
CACNB2
(HGNC:1402)
short QT syndrome
(MONDO_0000453)
Moderate
CACNB4
(HGNC:1404)
juvenile myoclonic epilepsy
(MONDO_0009696)
Limited
CACNB4
(HGNC:1404)
epilepsy
(MONDO_0005027)
Strong
HDAC4
(HGNC:14063)
2q37 microdeletion syndrome
(MONDO_0010886)
Definitive
BACH2
(HGNC:14078)
immunodeficiency 60
(MONDO_0032723)
Limited
XPO7
(HGNC:14108)
prostate cancer
(MONDO_0008315)
Limited
NPRL3
(HGNC:14124)
focal epilepsy
(MONDO_0005384)
Strong
NPRL3
(HGNC:14124)
familial focal epilepsy with variable foci
(MONDO_0020310)
Strong
DOCK9
(HGNC:14132)
keratoconus
(MONDO_0015486)
Limited
EHMT2
(HGNC:14129)
neurodevelopmental disorder
(MONDO_0700092)
Limited
PIGQ
(HGNC:14135)
developmental and epileptic encephalopathy, 77
(MONDO_0032808)
Moderate
ELAC2
(HGNC:14198)
mitochondrial disease
(MONDO_0044970)
Moderate
JPH2
(HGNC:14202)
dilated cardiomyopathy
(MONDO_0005021)
Limited
JPH2
(HGNC:14202)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
JPH3
(HGNC:14203)
Huntington disease-like 2
(MONDO_0011671)
Strong
RAB23
(HGNC:14263)
RAB23-related Carpenter syndrome
(MONDO_0008710)
Moderate
RAB18
(HGNC:14244)
Warburg micro syndrome
(MONDO_0016649)
Strong
AUTS2
(HGNC:14262)
autism spectrum disorder due to AUTS2 deficiency
(MONDO_0014361)
Strong
PCDH19
(HGNC:14270)
developmental and epileptic encephalopathy, 9
(MONDO_0010246)
Strong
IRF2BPL
(HGNC:14282)
neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures
(MONDO_0060759)
Strong
EDARADD
(HGNC:14341)
tooth agenesis
(MONDO_0005486)
Limited
MRTFA
(HGNC:14334)
immunodeficiency 66
(MONDO_0030013)
Limited
WDR13
(HGNC:14352)
intellectual disability
(MONDO_0001071)
Limited
C1QTNF5
(HGNC:14344)
late-onset retinal degeneration
(MONDO_0011579)
Strong
ACP4
(HGNC:14376)
amelogenesis imperfecta type 1
(MONDO_0015047)
Limited
HTRA2
(HGNC:14348)
3-methylglutaconic aciduria type 8
(MONDO_0044723)
Limited
ACTC1
(HGNC:143)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
NOP10
(HGNC:14378)
dyskeratosis congenita
(MONDO_0015780)
Limited
ACTC1
(HGNC:143)
dilated cardiomyopathy
(MONDO_0005021)
Strong
SLC25A19
(HGNC:14409)
Leigh syndrome
(MONDO_0009723)
Limited
NHP2
(HGNC:14377)
dyskeratosis congenita
(MONDO_0015780)
Strong
SLC25A19
(HGNC:14409)
Amish lethal microcephaly
(MONDO_0011790)
Strong
ELOVL4
(HGNC:14415)
spinocerebellar ataxia type 34
(MONDO_0007574)
Strong
ELOVL4
(HGNC:14415)
Stargardt disease 3
(MONDO_0010819)
Strong
CALM1
(HGNC:1442)
long QT syndrome 14
(MONDO_0014548)
Strong
ELOVL4
(HGNC:14415)
congenital ichthyosis-intellectual disability-spastic quadriplegia syndrome
(MONDO_0013760)
Moderate
ELOVL4
(HGNC:14415)
Stargardt disease
(MONDO_0019353)
Limited
SLC13A3
(HGNC:14430)
leukoencephalopathy, acute reversible, with increased urinary alpha-ketoglutarate
(MONDO_0032716)
Strong
CALM1
(HGNC:1442)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Definitive
LPIN2
(HGNC:14450)
Majeed syndrome
(MONDO_0012316)
Strong
TMEM237
(HGNC:14432)
Joubert syndrome
(MONDO_0018772)
Limited
CALM2
(HGNC:1445)
long QT syndrome
(MONDO_0002442)
Strong
CALM2
(HGNC:1445)
long QT syndrome 15
(MONDO_0014550)
Moderate
CALM3
(HGNC:1449)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Moderate
SLC26A9
(HGNC:14469)
cystic fibrosis
(MONDO_0009061)
Moderate
SLC26A7
(HGNC:14467)
congenital hypothyroidism
(MONDO_0018612)
Moderate
CALM2
(HGNC:1445)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Strong
ACTG1
(HGNC:144)
Baraitser-winter syndrome 2
(MONDO_0013812)
Limited
CALM3
(HGNC:1449)
familial long QT syndrome
(MONDO_0019171)
Strong
WNK1
(HGNC:14540)
hereditary sensory and autonomic neuropathy type 2
(MONDO_0019941)
Strong
ACTG1
(HGNC:144)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Definitive
NPC2
(HGNC:14537)
Niemann-Pick disease, type C2
(MONDO_0011873)
Strong
CDHR1
(HGNC:14550)
cone-rod dystrophy
(MONDO_0015993)
Strong
CDHR1
(HGNC:14550)
retinitis pigmentosa
(MONDO_0019200)
Strong
PINK1
(HGNC:14581)
autosomal recessive early-onset Parkinson disease 6
(MONDO_0011613)
Strong
ACTG2
(HGNC:145)
familial visceral myopathy
(MONDO_0016829)
Strong
PINK1
(HGNC:14581)
young-onset Parkinson disease
(MONDO_0017279)
Moderate
ACTG2
(HGNC:145)
visceral myopathy 1
(MONDO_0020754)
Definitive
CAMK2B
(HGNC:1461)
intellectual disability, autosomal dominant 54
(MONDO_0030920)
Strong
CAMK2A
(HGNC:1460)
intellectual disability, autosomal dominant 53
(MONDO_0030919)
Strong
ADAMTSL2
(HGNC:14631)
geleophysic dysplasia 1
(MONDO_0009269)
Definitive
ADAMTSL2
(HGNC:14631)
Ehlers-Danlos syndrome
(MONDO_0020066)
Limited
CRELD1
(HGNC:14630)
congenital heart disease
(MONDO_0005453)
Moderate
ABCA13
(HGNC:14638)
schizophrenia
(MONDO_0005090)
Strong
PCDH15
(HGNC:14674)
Usher syndrome type 1
(MONDO_0010168)
Definitive
PCDH15
(HGNC:14674)
Usher syndrome type 1F
(MONDO_0011186)
Definitive
PCDH15
(HGNC:14674)
autosomal recessive nonsyndromic hearing loss 23
(MONDO_0012293)
Moderate
DEAF1
(HGNC:14677)
intellectual disability, autosomal dominant 24
(MONDO_0014357)
Strong
CAPN3
(HGNC:1480)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Definitive
CAPN1
(HGNC:1476)
autosomal recessive spastic paraplegia type 76
(MONDO_0014827)
Strong
CAPN3
(HGNC:1480)
muscular dystrophy, limb-girdle, autosomal dominant
(MONDO_0015151)
Limited
CAPN3
(HGNC:1480)
muscular dystrophy, limb-girdle, autosomal dominant 4
(MONDO_0029133)
Limited
COG5
(HGNC:14857)
COG5-congenital disorder of glycosylation
(MONDO_0013325)
Limited
DNAJB6
(HGNC:14888)
autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6)
(MONDO_0021018)
Strong
SPTBN4
(HGNC:14896)
neurodevelopmental disorder with hypotonia, neuropathy, and deafness
(MONDO_0060496)
Strong
DNAJB11
(HGNC:14889)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Strong
PUM1
(HGNC:14957)
spinocerebellar ataxia 47
(MONDO_0033482)
Strong
PIGT
(HGNC:14938)
multiple congenital anomalies-hypotonia-seizures syndrome 3
(MONDO_0014165)
Strong
CASK
(HGNC:1497)
syndromic X-linked intellectual disability Najm type
(MONDO_0010417)
Definitive
POFUT1
(HGNC:14988)
Dowling-Degos disease
(MONDO_0008371)
Strong
SNX14
(HGNC:14977)
autosomal recessive spinocerebellar ataxia 20
(MONDO_0014601)
Strong
GPR101
(HGNC:14963)
acromegaly
(MONDO_0019933)
Strong
CASP8
(HGNC:1509)
autoimmune lymphoproliferative syndrome type 2B
(MONDO_0011804)
Moderate
CASQ1
(HGNC:1512)
tubular aggregate myopathy
(MONDO_0008051)
Strong
CASQ2
(HGNC:1513)
catecholaminergic polymorphic ventricular tachycardia 2
(MONDO_0012762)
Definitive
CASR
(HGNC:1514)
familial hypocalciuric hypercalcemia 1
(MONDO_0007791)
Definitive
CASR
(HGNC:1514)
autosomal dominant hypocalcemia
(MONDO_0018543)
Strong
CASR
(HGNC:1514)
neonatal severe primary hyperparathyroidism
(MONDO_0009397)
Strong
CAT
(HGNC:1516)
acatalasia
(MONDO_0013571)
Definitive
CASR
(HGNC:1514)
autosomal dominant hypocalcemia 1
(MONDO_0011013)
Definitive
CAV1
(HGNC:1527)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
CAV3
(HGNC:1529)
long QT syndrome
(MONDO_0002442)
Limited
CAV3
(HGNC:1529)
Brugada syndrome
(MONDO_0015263)
Limited
CAV1
(HGNC:1527)
heritable pulmonary arterial hypertension
(MONDO_0017148)
Limited
MICU1
(HGNC:1530)
proximal myopathy with extrapyramidal signs
(MONDO_0014300)
Strong
SERPINA6
(HGNC:1540)
corticosteroid-binding globulin deficiency
(MONDO_0012675)
Limited
CAV3
(HGNC:1529)
rippling muscle disease 2
(MONDO_0019947)
Moderate
CBL
(HGNC:1541)
CBL-related disorder
(MONDO_0013308)
Definitive
CBL
(HGNC:1541)
juvenile myelomonocytic leukemia
(MONDO_0011908)
Definitive
CBL
(HGNC:1541)
Noonan syndrome
(MONDO_0018997)
Strong
SHOC2
(HGNC:15454)
Costello syndrome
(MONDO_0009026)
Disputed
PRPF31
(HGNC:15446)
retinitis pigmentosa 11
(MONDO_0010828)
Definitive
SHOC2
(HGNC:15454)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Moderate
SHOC2
(HGNC:15454)
Noonan syndrome-like disorder with loose anagen hair
(MONDO_0011899)
Strong
MBTPS2
(HGNC:15455)
osteogenesis imperfecta
(MONDO_0019019)
Moderate
MBTPS2
(HGNC:15455)
BRESEK syndrome
(MONDO_0019414)
Strong
MBTPS1
(HGNC:15456)
spondyloepiphyseal dysplasia, kondo-fu type
(MONDO_0032721)
Moderate
DIAPH3
(HGNC:15480)
auditory neuropathy
(MONDO_0021944)
Limited
MBTPS2
(HGNC:15455)
keratosis follicularis spinulosa decalvans
(MONDO_0000136)
Strong
DNAJC6
(HGNC:15469)
young-onset Parkinson disease
(MONDO_0017279)
Moderate
ANKH
(HGNC:15492)
craniometaphyseal dysplasia, autosomal dominant
(MONDO_0007397)
Limited
ANKH
(HGNC:15492)
craniometaphyseal dysplasia
(MONDO_0015465)
Strong
PUS1
(HGNC:15508)
myopathy, lactic acidosis, and sideroblastic anemia
(MONDO_0000863)
Strong
ANKH
(HGNC:15492)
chondrocalcinosis 2
(MONDO_0007319)
Strong
XYLT1
(HGNC:15516)
Desbuquois dysplasia 2
(MONDO_0014343)
Strong
XYLT1
(HGNC:15516)
Desbuquois dysplasia
(MONDO_0015426)
Strong
DCTN4
(HGNC:15518)
cystic fibrosis
(MONDO_0009061)
Limited
CBS
(HGNC:1550)
classic homocystinuria
(MONDO_0009352)
Definitive
LPAR6
(HGNC:15520)
isolated familial wooly hair disorder
(MONDO_0008686)
Strong
LPAR6
(HGNC:15520)
hypotrichosis 8
(MONDO_0010206)
Strong
LPAR6
(HGNC:15520)
hypotrichosis simplex
(MONDO_0018914)
Strong
JAM3
(HGNC:15532)
porencephaly-microcephaly-bilateral congenital cataract syndrome
(MONDO_0013394)
Strong
SPRY4
(HGNC:15533)
Kallmann syndrome
(MONDO_0018800)
Limited
CHCHD10
(HGNC:15559)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
IL36RN
(HGNC:15561)
pustulosis palmaris et plantaris
(MONDO_0015597)
Limited
SETBP1
(HGNC:15573)
Schinzel-Giedion syndrome
(MONDO_0010010)
Definitive
SS18L1
(HGNC:15592)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
SETBP1
(HGNC:15573)
intellectual disability, autosomal dominant 29
(MONDO_0014482)
Strong
HAMP
(HGNC:15598)
hemochromatosis type 2
(MONDO_0019257)
Strong
NBAS
(HGNC:15625)
short stature-optic atrophy-Pelger-HuC+t anomaly syndrome
(MONDO_0013889)
Strong
NBAS
(HGNC:15625)
infantile liver failure syndrome 2
(MONDO_0014659)
Definitive
KLHL7
(HGNC:15646)
PERCHING syndrome
(MONDO_0014890)
Limited
TLR7
(HGNC:15631)
systemic lupus erythematosus
(MONDO_0007915)
Strong
KLHL7
(HGNC:15646)
retinitis pigmentosa
(MONDO_0019200)
Strong
ALG9
(HGNC:15672)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Strong
ALG9
(HGNC:15672)
Gillessen-Kaesbach-Nishimura syndrome
(MONDO_0009890)
Strong
PHIP
(HGNC:15673)
PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome
(MONDO_0035133)
Strong
CTTNBP2
(HGNC:15679)
autism spectrum disorder
(MONDO_0005258)
Limited
LDB3
(HGNC:15710)
myofibrillar myopathy 4
(MONDO_0012277)
Limited
LDB3
(HGNC:15710)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
LDB3
(HGNC:15710)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
ALG9
(HGNC:15672)
ALG9-congenital disorder of glycosylation
(MONDO_0012117)
Strong
LDB3
(HGNC:15710)
familial dilated cardiomyopathy
(MONDO_0016333)
Moderate
LRPPRC
(HGNC:15714)
Leigh syndrome
(MONDO_0009723)
Strong
LRPPRC
(HGNC:15714)
congenital lactic acidosis, Saguenay-Lac-Saint-Jean type
(MONDO_0009069)
Strong
GEMIN4
(HGNC:15717)
neurodevelopmental disorder with microcephaly, cataracts, and renal abnormalities
(MONDO_0060664)
Strong
OBSCN
(HGNC:15719)
dilated cardiomyopathy
(MONDO_0005021)
Limited
OBSCN
(HGNC:15719)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
OSBPL2
(HGNC:15761)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Moderate
KRIT1
(HGNC:1573)
famililal cerebral cavernous malformations
(MONDO_0031037)
Definitive
ULK4
(HGNC:15784)
prostate cancer
(MONDO_0008315)
Limited
GATA5
(HGNC:15802)
familial bicuspid aortic valve
(MONDO_0007194)
Disputed
GATA5
(HGNC:15802)
familial atrial fibrillation
(MONDO_0018054)
Limited
GATA5
(HGNC:15802)
tetralogy of fallot
(MONDO_0008542)
Moderate
OVOL2
(HGNC:15804)
posterior polymorphous corneal dystrophy 1
(MONDO_0007378)
Moderate
ANKRD1
(HGNC:15819)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
ANKRD1
(HGNC:15819)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
BSCL2
(HGNC:15832)
hereditary spastic paraplegia 17
(MONDO_0010043)
Strong
BSCL2
(HGNC:15832)
neonatal diabetes mellitus
(MONDO_0016391)
Limited
BSCL2
(HGNC:15832)
congenital generalized lipodystrophy type 2
(MONDO_0010020)
Definitive
OVOL2
(HGNC:15804)
posterior polymorphous corneal dystrophy
(MONDO_0020364)
Strong
BSCL2
(HGNC:15832)
distal hereditary motor neuropathy
(MONDO_0018894)
Definitive
PROKR2
(HGNC:15836)
septooptic dysplasia
(MONDO_0008428)
Limited
PROKR2
(HGNC:15836)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
CCND2
(HGNC:1583)
megalencephaly-polymicrogyria-postaxial polydactyly-hydrocephalus syndrome
(MONDO_0019375)
Definitive
PROKR2
(HGNC:15836)
Kallmann syndrome
(MONDO_0018800)
Strong
KMT2B
(HGNC:15840)
dystonia 28, childhood-onset
(MONDO_0015004)
Definitive
KMT2B
(HGNC:15840)
intellectual developmental disorder, autosomal dominant 68
(MONDO_0030969)
Strong
TASP1
(HGNC:15859)
Suleiman-El-Hattab syndrome
(MONDO_0033532)
Strong
ARFGEF2
(HGNC:15853)
periventricular nodular heterotopia
(MONDO_0020341)
Limited
PRPF6
(HGNC:15860)
retinitis pigmentosa
(MONDO_0019200)
Strong
RBCK1
(HGNC:15864)
polyglucosan body myopathy 1 with or without immunodeficiency
(MONDO_0014389)
Strong
KIZ
(HGNC:15865)
retinitis pigmentosa
(MONDO_0019200)
Strong
TMEM230
(HGNC:15876)
Parkinson disease
(MONDO_0005180)
Limited
MYH7B
(HGNC:15906)
left ventricular noncompaction
(MONDO_0018901)
Limited
RTEL1
(HGNC:15888)
Hoyeraal-Hreidarsson syndrome
(MONDO_0018045)
Strong
RTEL1
(HGNC:15888)
dyskeratosis congenita
(MONDO_0015780)
Definitive
NOP56
(HGNC:15911)
spinocerebellar ataxia type 36
(MONDO_0013594)
Strong
PLCB1
(HGNC:15917)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
PLCB1
(HGNC:15917)
malignant migrating partial seizures of infancy
(MONDO_0017385)
Limited
SALL4
(HGNC:15924)
Duane retraction syndrome
(MONDO_0007473)
Limited
SALL4
(HGNC:15924)
Duane-radial ray syndrome
(MONDO_0011812)
Strong
SAMHD1
(HGNC:15925)
Moyamoya disease
(MONDO_0016820)
Limited
RP1L1
(HGNC:15946)
retinitis pigmentosa
(MONDO_0019200)
Strong
SAMHD1
(HGNC:15925)
Aicardi-Goutieres syndrome 5
(MONDO_0013059)
Limited
GDAP1
(HGNC:15968)
Charcot-Marie-Tooth disease type 4A
(MONDO_0008961)
Definitive
GDAP1
(HGNC:15968)
Charcot-Marie-Tooth disease axonal type 2K
(MONDO_0011916)
Strong
TP63
(HGNC:15979)
ankyloblepharon-ectodermal defects-cleft lip/palate syndrome
(MONDO_0007124)
Strong
TP63
(HGNC:15979)
ADULT syndrome
(MONDO_0007072)
Strong
TP63
(HGNC:15979)
Rapp-Hodgkin syndrome
(MONDO_0007508)
Strong
TP63
(HGNC:15979)
split hand-foot malformation 4
(MONDO_0011535)
Limited
TP63
(HGNC:15979)
EEC syndrome
(MONDO_0010004)
Definitive
TP63
(HGNC:15979)
limb-mammary syndrome
(MONDO_0011334)
Moderate
TP63
(HGNC:15979)
split hand-foot malformation
(MONDO_0016576)
Limited
NAV3
(HGNC:15998)
neurodevelopmental disorder
(MONDO_0700092)
Strong
SELENON
(HGNC:15999)
congenital fiber-type disproportion myopathy
(MONDO_0009711)
Moderate
SELENON
(HGNC:15999)
rigid spine muscular dystrophy 1
(MONDO_0011271)
Definitive
SELENON
(HGNC:15999)
desmin-related myopathy with Mallory body-like inclusions
(MONDO_0019398)
Limited
SUGCT
(HGNC:16001)
glutaric acidemia type 3
(MONDO_0009283)
Strong
STRC
(HGNC:16035)
autosomal recessive nonsyndromic hearing loss 16
(MONDO_0011364)
Strong
CFAP52
(HGNC:16053)
situs inversus
(MONDO_0010029)
Limited
RAB33B
(HGNC:16075)
Smith-McCort dysplasia 2
(MONDO_0014087)
Limited
RAB33B
(HGNC:16075)
Smith-McCort dysplasia
(MONDO_0015799)
Strong
MCM8
(HGNC:16147)
colorectal cancer
(MONDO_0005575)
Limited
TBC1D20
(HGNC:16133)
Warburg micro syndrome
(MONDO_0016649)
Strong
ACTL6B
(HGNC:160)
developmental and epileptic encephalopathy, 76
(MONDO_0032768)
Strong
SLC17A9
(HGNC:16192)
disseminated superficial actinic porokeratosis
(MONDO_0019212)
Limited
RSPO4
(HGNC:16175)
nonsyndromic congenital nail disorder 4
(MONDO_0008798)
Strong
TP53RK
(HGNC:16197)
Galloway-Mowat syndrome
(MONDO_0009627)
Strong
ACTL7A
(HGNC:161)
male infertility
(MONDO_0005372)
Strong
MGME1
(HGNC:16205)
mitochondrial DNA depletion syndrome 11
(MONDO_0014039)
Limited
DNAJC5
(HGNC:16235)
ceroid lipofuscinosis, neuronal, 4 (Kufs type)
(MONDO_0008083)
Definitive
DNAJC5
(HGNC:16235)
adult neuronal ceroid lipofuscinosis
(MONDO_0019260)
Strong
MYLK2
(HGNC:16243)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
SUN5
(HGNC:16252)
spermatogenic failure 16
(MONDO_0014961)
Definitive
SLC19A3
(HGNC:16266)
Leigh syndrome
(MONDO_0009723)
Strong
PNPLA6
(HGNC:16268)
cerebellar ataxia-hypogonadism syndrome
(MONDO_0008935)
Strong
PNPLA6
(HGNC:16268)
Laurence-Moon syndrome
(MONDO_0009514)
Definitive
PNPLA6
(HGNC:16268)
hereditary spastic paraplegia 39
(MONDO_0012787)
Limited
PNPLA6
(HGNC:16268)
trichomegaly-retina pigmentary degeneration-dwarfism syndrome
(MONDO_0010152)
Definitive
NFU1
(HGNC:16287)
multiple mitochondrial dysfunctions syndrome 1
(MONDO_0011582)
Strong
UPB1
(HGNC:16297)
beta-ureidopropionase deficiency
(MONDO_0013164)
Disputed
CD19
(HGNC:1633)
common variable immunodeficiency
(MONDO_0015517)
Strong
USH1G
(HGNC:16356)
Usher syndrome type 1
(MONDO_0010168)
Moderate
USH1G
(HGNC:16356)
Usher syndrome type 1G
(MONDO_0011748)
Limited
WHRN
(HGNC:16361)
Usher syndrome type 2
(MONDO_0016484)
Limited
PARK7
(HGNC:16369)
young-onset Parkinson disease
(MONDO_0017279)
Strong
TRIM22
(HGNC:16379)
inflammatory bowel disease
(MONDO_0005265)
Moderate
TRIM32
(HGNC:16380)
Bardet-Biedl syndrome 11
(MONDO_0014439)
Limited
TRIM32
(HGNC:16380)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Moderate
TRIM32
(HGNC:16380)
Bardet-Biedl syndrome
(MONDO_0015229)
Limited
CARD11
(HGNC:16393)
immunodeficiency 11b with atopic dermatitis
(MONDO_0054697)
Limited
CARD11
(HGNC:16393)
BENTA disease
(MONDO_0014645)
Strong
NLRP3
(HGNC:16400)
keratitis fugax hereditaria
(MONDO_0007849)
Limited
NLRP3
(HGNC:16400)
Muckle-Wells syndrome
(MONDO_0008633)
Definitive
NLRP3
(HGNC:16400)
CINCA syndrome
(MONDO_0011776)
Definitive
NLRP3
(HGNC:16400)
cryopyrin-associated periodic syndrome
(MONDO_0016168)
Definitive
NLRP3
(HGNC:16400)
familial cold autoinflammatory syndrome
(MONDO_0018768)
Strong
EFHC1
(HGNC:16406)
epilepsy
(MONDO_0005027)
Limited
EFHC1
(HGNC:16406)
juvenile myoclonic epilepsy
(MONDO_0009696)
Strong
SLC4A11
(HGNC:16438)
Fuchs' endothelial dystrophy
(MONDO_0005321)
Strong
SLC4A11
(HGNC:16438)
congenital hereditary endothelial dystrophy of cornea
(MONDO_0009019)
Definitive
SLC4A11
(HGNC:16438)
corneal dystrophy-perceptive deafness syndrome
(MONDO_0009015)
Definitive
SUFU
(HGNC:16466)
medulloblastoma
(MONDO_0007959)
Strong
SUFU
(HGNC:16466)
Joubert syndrome
(MONDO_0018772)
Moderate
SLC45A2
(HGNC:16472)
oculocutaneous albinism type 4
(MONDO_0011683)
Definitive
NME8
(HGNC:16473)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
ZMIZ1
(HGNC:16493)
neurodevelopmental disorder with dysmorphic facies and distal skeletal anomalies
(MONDO_0032855)
Strong
RAB39B
(HGNC:16499)
early-onset parkinsonism-intellectual disability syndrome
(MONDO_0010709)
Strong
BPIFC
(HGNC:16503)
trichilemmal cyst
(MONDO_0012328)
Limited
ZMIZ1
(HGNC:16493)
syndromic intellectual disability
(MONDO_0000508)
Strong
BSND
(HGNC:16512)
Bartter disease type 4A
(MONDO_0011242)
Strong
BSND
(HGNC:16512)
Bartter syndrome type 4
(MONDO_0019524)
Strong
TMC1
(HGNC:16513)
autosomal dominant nonsyndromic hearing loss 36
(MONDO_0011708)
Strong
RAPGEF4
(HGNC:16626)
prostate cancer
(MONDO_0008315)
Limited
CHEK2
(HGNC:16627)
familial ovarian cancer
(MONDO_0016248)
Limited
TMC1
(HGNC:16513)
nonsyndromic genetic hearing loss
(MONDO_0019497)
Definitive
CHEK2
(HGNC:16627)
hereditary breast carcinoma
(MONDO_0016419)
Strong
CHEK2
(HGNC:16627)
hereditary nonpolyposis colon cancer
(MONDO_0018630)
Limited
KGD4
(HGNC:16631)
Leigh syndrome
(MONDO_0009723)
Limited
CHEK2
(HGNC:16627)
acute myeloid leukemia
(MONDO_0018874)
Disputed
KIF1B
(HGNC:16636)
Charcot-Marie-Tooth disease type 2A1
(MONDO_0007308)
Limited
KIF1B
(HGNC:16636)
pheochromocytoma
(MONDO_0008233)
Limited
CD36
(HGNC:1663)
platelet-type bleeding disorder 10
(MONDO_0012031)
Strong
SRRM2
(HGNC:16639)
intellectual developmental disorder, autosomal dominant 72
(MONDO_0957397)
Strong
IFITM5
(HGNC:16644)
osteogenesis imperfecta type 5
(MONDO_0012591)
Definitive
SCARB2
(HGNC:1665)
Unverricht-Lundborg syndrome
(MONDO_0009698)
Strong
SCARB2
(HGNC:1665)
action myoclonus-renal failure syndrome
(MONDO_0009699)
Definitive
SCARB2
(HGNC:1665)
progressive myoclonus epilepsy
(MONDO_0020074)
Strong
TUBGCP4
(HGNC:16691)
microcephaly and chorioretinopathy 3
(MONDO_0014592)
Strong
ZFPM2
(HGNC:16700)
tetralogy of fallot
(MONDO_0008542)
Moderate
MCEE
(HGNC:16732)
methylmalonic acidemia due to methylmalonyl-CoA epimerase deficiency
(MONDO_0009615)
Strong
BCAP31
(HGNC:16695)
severe motor and intellectual disabilities-sensorineural deafness-dystonia syndrome
(MONDO_0010334)
Moderate
DHX30
(HGNC:16716)
neurodevelopmental disorder with severe motor impairment and absent language
(MONDO_0060622)
Definitive
ZBTB11
(HGNC:16740)
intellectual developmental disorder, autosomal recessive 69
(MONDO_0032715)
Strong
FBXO32
(HGNC:16731)
dilated cardiomyopathy
(MONDO_0005021)
Strong
CDC73
(HGNC:16783)
hyperparathyroidism 2 with jaw tumors
(MONDO_0007768)
Definitive
CD3D
(HGNC:1673)
immunodeficiency 19
(MONDO_0014280)
Limited
ZNF423
(HGNC:16762)
nephronophthisis
(MONDO_0019005)
Limited
TAOK2
(HGNC:16835)
autism spectrum disorder
(MONDO_0005258)
Strong
COQ8A
(HGNC:16812)
autosomal recessive ataxia due to ubiquinone deficiency
(MONDO_0012784)
Definitive
COQ8A
(HGNC:16812)
coenzyme Q10 deficiency
(MONDO_0018151)
Strong
LITAF
(HGNC:16841)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
CDC73
(HGNC:16783)
familial isolated hyperparathyroidism
(MONDO_0015027)
Strong
CDC73
(HGNC:16783)
parathyroid gland carcinoma
(MONDO_0012004)
Strong
LITAF
(HGNC:16841)
Charcot-Marie-Tooth disease type 1C
(MONDO_0010995)
Strong
FIG4
(HGNC:16873)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Definitive
FIG4
(HGNC:16873)
Yunis-Varon syndrome
(MONDO_0008995)
Strong
RAPGEF2
(HGNC:16854)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
CD59
(HGNC:1689)
primary CD59 deficiency
(MONDO_0012858)
Strong
BCKDK
(HGNC:16902)
branched-chain keto acid dehydrogenase kinase deficiency
(MONDO_0013970)
Definitive
NEBL
(HGNC:16932)
dilated cardiomyopathy
(MONDO_0005021)
Strong
DGAT2
(HGNC:16940)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Limited
ERLIN1
(HGNC:16947)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
ERLIN1
(HGNC:16947)
hereditary spastic paraplegia 62
(MONDO_0014302)
Moderate
ARPP21
(HGNC:16968)
amyotrophic lateral sclerosis
(MONDO_0004976)
Refuted
RRAGA
(HGNC:16963)
cataract
(MONDO_0005129)
Moderate
TRIOBP
(HGNC:17009)
autosomal recessive nonsyndromic hearing loss 28
(MONDO_0012355)
Strong
PRICKLE1
(HGNC:17019)
epilepsy
(MONDO_0005027)
Limited
PRICKLE1
(HGNC:17019)
progressive myoclonus epilepsy
(MONDO_0020074)
Moderate
CD81
(HGNC:1701)
common variable immunodeficiency
(MONDO_0015517)
Limited
PRICKLE1
(HGNC:17019)
Unverricht-Lundborg syndrome
(MONDO_0009698)
Refuted
ASTN2
(HGNC:17021)
intellectual disability
(MONDO_0001071)
Limited
ASTN2
(HGNC:17021)
autism spectrum disorder
(MONDO_0005258)
Moderate
MFN2
(HGNC:16877)
Charcot-Marie-Tooth disease type 2A2
(MONDO_0012231)
Definitive
SART3
(HGNC:16860)
disseminated superficial actinic porokeratosis
(MONDO_0019212)
Limited
FIG4
(HGNC:16873)
Charcot-Marie-Tooth disease type 4J
(MONDO_0012640)
Definitive
FIG4
(HGNC:16873)
amyotrophic lateral sclerosis
(MONDO_0004976)
Moderate
EXOSC8
(HGNC:17035)
pontocerebellar hypoplasia, type 1C
(MONDO_0014485)
Strong
MFN2
(HGNC:16877)
hereditary motor and sensory neuropathy type 6
(MONDO_0019551)
Strong
FIG4
(HGNC:16873)
amyotrophic lateral sclerosis type 11
(MONDO_0012945)
Limited
TNIP1
(HGNC:16903)
systemic lupus erythematosus
(MONDO_0007915)
Moderate
HCN4
(HGNC:16882)
familial sick sinus syndrome
(MONDO_0012061)
Strong
RPH3A
(HGNC:17056)
congenital myasthenic syndrome
(MONDO_0018940)
Limited
EXOSC8
(HGNC:17035)
pontocerebellar hypoplasia type 1
(MONDO_0016396)
Limited
RPH3A
(HGNC:17056)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
MFN2
(HGNC:16877)
multiple symmetric lipomatosis
(MONDO_0007908)
Moderate
NIPA1
(HGNC:17043)
hereditary spastic paraplegia 6
(MONDO_0010878)
Definitive
ICOSLG
(HGNC:17087)
combined immunodeficiency
(MONDO_0015131)
Limited
SYNE1
(HGNC:17089)
autosomal recessive ataxia, Beauce type
(MONDO_0012549)
Strong
LARS2
(HGNC:17095)
Perrault syndrome
(MONDO_0017312)
Definitive
DICER1
(HGNC:17098)
pleuropulmonary blastoma
(MONDO_0011014)
Definitive
DICER1
(HGNC:17098)
DICER1-related tumor predisposition
(MONDO_0100216)
Definitive
RAB3GAP1
(HGNC:17063)
Warburg micro syndrome 1
(MONDO_0010822)
Definitive
DICER1
(HGNC:17098)
global developmental delay - lung cysts - overgrowth - Wilms tumor syndrome
(MONDO_0018445)
Moderate
SUZ12
(HGNC:17101)
Imagawa-Matsumoto syndrome
(MONDO_0032916)
Moderate
SUZ12
(HGNC:17101)
Weaver syndrome
(MONDO_0010193)
Strong
CDON
(HGNC:17104)
pituitary stalk interruption syndrome
(MONDO_0019828)
Limited
TNPO3
(HGNC:17103)
autosomal dominant limb-girdle muscular dystrophy type 1F
(MONDO_0012034)
Strong
ADAMTS17
(HGNC:17109)
Weill-Marchesani 4 syndrome, recessive
(MONDO_0013176)
Strong
CDAN1
(HGNC:1713)
congenital dyserythropoietic anemia type 1
(MONDO_0020337)
Definitive
CDAN1
(HGNC:1713)
congenital dyserythropoietic anemia
(MONDO_0019403)
Definitive
OPTN
(HGNC:17142)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
ORC6
(HGNC:17151)
Meier-Gorlin syndrome
(MONDO_0016817)
Strong
RAB3GAP2
(HGNC:17168)
Warburg micro syndrome 2
(MONDO_0013641)
Strong
CDC14A
(HGNC:1718)
autosomal recessive nonsyndromic hearing loss 32
(MONDO_0012091)
Strong
NDUFA13
(HGNC:17194)
mitochondrial complex 1 deficiency, nuclear type 28
(MONDO_0032632)
Strong
ACVR1
(HGNC:171)
congenital heart disease
(MONDO_0005453)
Limited
DHX37
(HGNC:17210)
46,XY complete gonadal dysgenesis
(MONDO_0010765)
Strong
CHSY1
(HGNC:17198)
temtamy preaxial brachydactyly syndrome
(MONDO_0011533)
Strong
POLR1A
(HGNC:17264)
acrofacial dysostosis Cincinnati type
(MONDO_0014651)
Moderate
AGTPBP1
(HGNC:17258)
pontocerebellar hypoplasia type 1
(MONDO_0016396)
Moderate
COLEC11
(HGNC:17213)
3MC syndrome
(MONDO_0017398)
Strong
CENPJ
(HGNC:17272)
autosomal recessive primary microcephaly
(MONDO_0016660)
Limited
CENPJ
(HGNC:17272)
Seckel syndrome
(MONDO_0019342)
Strong
DHX37
(HGNC:17210)
46,XY sex reversal 11
(MONDO_8000015)
Strong
RRM2B
(HGNC:17296)
Kearns-Sayre syndrome
(MONDO_0010787)
Limited
APOA5
(HGNC:17288)
hyperlipoproteinemia type V
(MONDO_0007762)
Moderate
SP7
(HGNC:17321)
osteogenesis imperfecta type 12
(MONDO_0013460)
Limited
RIMS1
(HGNC:17282)
autism spectrum disorder
(MONDO_0005258)
Limited
RRM2B
(HGNC:17296)
mitochondrial neurogastrointestinal encephalomyopathy
(MONDO_0017575)
Limited
WAC
(HGNC:17327)
DeSanto-Shinawi syndrome
(MONDO_0018760)
Strong
DTNBP1
(HGNC:17328)
Hermansky-Pudlak syndrome 7
(MONDO_0013559)
Limited
CDK13
(HGNC:1733)
syndromic intellectual disability
(MONDO_0000508)
Strong
PRPF8
(HGNC:17340)
glaucoma
(MONDO_0005041)
Strong
PRPF8
(HGNC:17340)
retinitis pigmentosa
(MONDO_0019200)
Strong
BRWD3
(HGNC:17342)
childhood epilepsy with centrotemporal spikes
(MONDO_0007295)
Limited
PRPF8
(HGNC:17340)
neurodevelopmental disorder
(MONDO_0700092)
Limited
PRPF3
(HGNC:17348)
retinitis pigmentosa
(MONDO_0019200)
Strong
BRWD3
(HGNC:17342)
West syndrome
(MONDO_0018097)
Limited
CDC42
(HGNC:1736)
macrothrombocytopenia-lymphedema-developmental delay-facial dysmorphism-camptodactyly syndrome
(MONDO_0014757)
Moderate
PRPF4
(HGNC:17349)
retinitis pigmentosa
(MONDO_0019200)
Strong
CDC45
(HGNC:1739)
Meier-Gorlin syndrome
(MONDO_0016817)
Strong
CDC45
(HGNC:1739)
Meier-Gorlin syndrome 7
(MONDO_0014894)
Limited
TPK1
(HGNC:17358)
Leigh syndrome
(MONDO_0009723)
Strong
HOMER2
(HGNC:17513)
nonsyndromic genetic hearing loss
(MONDO_0019497)
Strong
CLCF1
(HGNC:17412)
cold-induced sweating syndrome
(MONDO_0015526)
Moderate
CDH15
(HGNC:1754)
intellectual disability
(MONDO_0001071)
Limited
CDC6
(HGNC:1744)
Meier-Gorlin syndrome 5
(MONDO_0013432)
Limited
CDH1
(HGNC:1748)
hereditary diffuse gastric adenocarcinoma
(MONDO_0007648)
Strong
CDH2
(HGNC:1759)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Moderate
SPEN
(HGNC:17575)
Radio-Tartaglia syndrome
(MONDO_0859143)
Strong
KAT6B
(HGNC:17582)
RASopathy
(MONDO_0021060)
Limited
CDH2
(HGNC:1759)
agenesis of corpus callosum, cardiac, ocular, and genital syndrome
(MONDO_0030065)
Strong
ACVRL1
(HGNC:175)
telangiectasia, hereditary hemorrhagic, type 2
(MONDO_0010880)
Definitive
ZNF674
(HGNC:17625)
X-linked intellectual disability
(MONDO_0100284)
Disputed
NDE1
(HGNC:17619)
NDE1-related microhydranencephaly
(MONDO_0011504)
Moderate
ZNF674
(HGNC:17625)
intellectual disability
(MONDO_0001071)
Disputed
CDH3
(HGNC:1762)
EEM syndrome
(MONDO_0009155)
Limited
IL17RD
(HGNC:17616)
Kallmann syndrome
(MONDO_0018800)
Limited
CDC6
(HGNC:1744)
Meier-Gorlin syndrome
(MONDO_0016817)
Limited
DACT1
(HGNC:17748)
Townes-Brocks syndrome
(MONDO_0007142)
Moderate
DCLRE1C
(HGNC:17642)
Omenn syndrome
(MONDO_0011338)
Definitive
ADGRV1
(HGNC:17416)
Usher syndrome type 2C
(MONDO_0011558)
Definitive
THSD1
(HGNC:17754)
non-immune hydrops fetalis
(MONDO_0009369)
Strong
CLCF1
(HGNC:17412)
Cold-induced sweating syndrome 1
(MONDO_0010091)
Moderate
TNFRSF13C
(HGNC:17755)
common variable immunodeficiency
(MONDO_0015517)
Moderate
CDK6
(HGNC:1777)
autosomal recessive primary microcephaly
(MONDO_0016660)
Moderate
MAP3K20
(HGNC:17797)
split hand-foot malformation
(MONDO_0016576)
Limited
ZFTRAF1
(HGNC:17806)
neurodevelopmental disorder
(MONDO_0700092)
Strong
NUP188
(HGNC:17859)
sandestig-stefanova syndrome
(MONDO_0032926)
Moderate
CDKN1B
(HGNC:1785)
multiple endocrine neoplasia type 4
(MONDO_0012552)
Strong
NT5C3A
(HGNC:17820)
hemolytic anemia due to pyrimidine 5' nucleotidase deficiency
(MONDO_0009946)
Strong
TRAF3IP1
(HGNC:17861)
Senior-Loken syndrome
(MONDO_0017842)
Limited
AFF4
(HGNC:17869)
cognitive impairment - coarse facies - heart defects - obesity - pulmonary involvement - short stature - skeletal dysplasia syndrome
(MONDO_0014609)
Moderate
CDKN1C
(HGNC:1786)
Silver-Russell syndrome
(MONDO_0008394)
Strong
CDH11
(HGNC:1750)
Elsahy-Waters syndrome
(MONDO_0008885)
Moderate
INVS
(HGNC:17870)
Senior-Loken syndrome
(MONDO_0017842)
Limited
INVS
(HGNC:17870)
nephronophthisis 2
(MONDO_0011190)
Limited
CDKN1B
(HGNC:1785)
multiple endocrine neoplasia
(MONDO_0017169)
Strong
NMNAT1
(HGNC:17877)
Leber congenital amaurosis 9
(MONDO_0012056)
Definitive
ADGRV1
(HGNC:17416)
Usher syndrome type 2
(MONDO_0016484)
Definitive
HOMER2
(HGNC:17513)
autosomal dominant nonsyndromic hearing loss 68
(MONDO_0014740)
Strong
NMNAT1
(HGNC:17877)
cone-rod dystrophy
(MONDO_0015993)
Moderate
SARS2
(HGNC:17697)
hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome
(MONDO_0013458)
Strong
GJC2
(HGNC:17494)
hypomyelinating leukodystrophy 2
(MONDO_0012125)
Definitive
NMNAT1
(HGNC:17877)
Leber congenital amaurosis
(MONDO_0018998)
Definitive
DACT1
(HGNC:17748)
Townes-Brocks syndrome 2
(MONDO_0054582)
Strong
CDKN2A
(HGNC:1787)
melanoma and neural system tumor syndrome
(MONDO_0007967)
Limited
CDKN2A
(HGNC:1787)
melanoma-pancreatic cancer syndrome
(MONDO_0011713)
Limited
GJC2
(HGNC:17494)
hereditary spastic paraplegia 44
(MONDO_0013179)
Limited
CDKN2B
(HGNC:1788)
renal cell carcinoma
(MONDO_0005086)
Strong
PGAP2
(HGNC:17893)
hyperphosphatasia with intellectual disability syndrome 3
(MONDO_0013628)
Strong
CDKN2A
(HGNC:1787)
familial atypical multiple mole melanoma syndrome
(MONDO_0018453)
Definitive
PSMC3IP
(HGNC:17928)
46 XX gonadal dysgenesis
(MONDO_0009299)
Limited
PGAP2
(HGNC:17893)
hyperphosphatasia-intellectual disability syndrome
(MONDO_0016596)
Strong
REEP2
(HGNC:17975)
hereditary spastic paraplegia
(MONDO_0019064)
Moderate
SLC22A12
(HGNC:17989)
hereditary renal hypouricemia
(MONDO_0009071)
Definitive
CDKN2A
(HGNC:1787)
melanoma, cutaneous malignant, susceptibility to, 2
(MONDO_0007964)
Strong
B3GALT6
(HGNC:17978)
spondyloepimetaphyseal dysplasia with joint laxity
(MONDO_0019675)
Definitive
TRPM4
(HGNC:17993)
erythrokeratodermia variabilis
(MONDO_0017851)
Moderate
EXOSC3
(HGNC:17944)
pontocerebellar hypoplasia type 1
(MONDO_0016396)
Definitive
FKRP
(HGNC:17997)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Strong
FKRP
(HGNC:17997)
muscular dystrophy-dystroglycanopathy type B5
(MONDO_0011688)
Definitive
TRPM4
(HGNC:17993)
Brugada syndrome
(MONDO_0015263)
Limited
FKRP
(HGNC:17997)
muscle-eye-brain disease
(MONDO_0018939)
Strong
AADAC
(HGNC:17)
Tourette syndrome
(MONDO_0007661)
Limited
CDSN
(HGNC:1802)
hypotrichosis 2
(MONDO_0007805)
Strong
FKRP
(HGNC:17997)
autosomal recessive limb-girdle muscular dystrophy type 2I
(MONDO_0011787)
Definitive
NUP160
(HGNC:18017)
familial idiopathic steroid-resistant nephrotic syndrome
(MONDO_0019006)
Limited
TMC6
(HGNC:18021)
epidermodysplasia verruciformis
(MONDO_0009176)
Definitive
ARID2
(HGNC:18037)
Coffin-Siris syndrome
(MONDO_0015452)
Strong
KDM5B
(HGNC:18039)
intellectual disability
(MONDO_0001071)
Moderate
ARID2
(HGNC:18037)
Coffin-Siris syndrome 6
(MONDO_0033492)
Strong
ARID1B
(HGNC:18040)
Coffin-Siris syndrome
(MONDO_0015452)
Definitive
PKD1L1
(HGNC:18053)
situs inversus
(MONDO_0010029)
Moderate
ARX
(HGNC:18060)
corpus callosum agenesis-abnormal genitalia syndrome
(MONDO_0010224)
Strong
ARX
(HGNC:18060)
X-linked lissencephaly with abnormal genitalia
(MONDO_0010268)
Definitive
ARX
(HGNC:18060)
West syndrome
(MONDO_0018097)
Strong
ARX
(HGNC:18060)
infantile epileptic-dyskinetic encephalopathy
(MONDO_0018226)
Strong
ARID1B
(HGNC:18040)
Coffin-Siris syndrome 1
(MONDO_0007617)
Definitive
ARX
(HGNC:18060)
Partington syndrome
(MONDO_0010654)
Definitive
ARX
(HGNC:18060)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
ARX
(HGNC:18060)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Moderate
TRPV4
(HGNC:18083)
autosomal dominant brachyolmia
(MONDO_0007232)
Strong
TRPV4
(HGNC:18083)
metatropic dysplasia
(MONDO_0007986)
Definitive
TRPV4
(HGNC:18083)
parastremmatic dwarfism
(MONDO_0008196)
Strong
TRPV4
(HGNC:18083)
scapuloperoneal spinal muscular atrophy, autosomal dominant
(MONDO_0008408)
Definitive
TRPV4
(HGNC:18083)
spondylometaphyseal dysplasia, Kozlowski type
(MONDO_0008477)
Strong
TRPV4
(HGNC:18083)
neuronopathy, distal hereditary motor, autosomal dominant 8
(MONDO_0010839)
Limited
TRPV4
(HGNC:18083)
familial digital arthropathy-brachydactyly
(MONDO_0011732)
Moderate
TRPV4
(HGNC:18083)
neuromuscular disease
(MONDO_0019056)
Limited
MFRP
(HGNC:18121)
nanophthalmia
(MONDO_0005514)
Definitive
SOX17
(HGNC:18122)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
AFG2A
(HGNC:18119)
microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome
(MONDO_0014698)
Strong
DCDC2
(HGNC:18141)
ciliopathy
(MONDO_0005308)
Strong
PHF6
(HGNC:18145)
Borjeson-Forssman-Lehmann syndrome
(MONDO_0010537)
Strong
TXNRD2
(HGNC:18155)
dilated cardiomyopathy
(MONDO_0005021)
Strong
FKBP10
(HGNC:18169)
osteogenesis imperfecta type 3
(MONDO_0009804)
Strong
FKBP10
(HGNC:18169)
osteogenesis imperfecta type 11
(MONDO_0012592)
Strong
FKBP10
(HGNC:18169)
Bruck syndrome 1
(MONDO_0009806)
Strong
FKBP10
(HGNC:18169)
arthrogryposis-like syndrome
(MONDO_0015241)
Strong
VPS33A
(HGNC:18179)
mucopolysaccharidosis-plus syndrome
(MONDO_0015012)
Definitive
GIPC3
(HGNC:18183)
autosomal recessive nonsyndromic hearing loss 15
(MONDO_0011160)
Strong
TMCO1
(HGNC:18188)
craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development 1
(MONDO_0800436)
Strong
RBFOX1
(HGNC:18222)
epilepsy
(MONDO_0005027)
Moderate
RCBTB1
(HGNC:18243)
exudative vitreoretinopathy
(MONDO_0019516)
Disputed
MOCOS
(HGNC:18234)
xanthinuria type II
(MONDO_0011346)
Limited
RBFOX1
(HGNC:18222)
neurodevelopmental disorder
(MONDO_0700092)
Strong
BANK1
(HGNC:18233)
systemic lupus erythematosus
(MONDO_0007915)
Limited
ATP6V0D2
(HGNC:18266)
Ehlers-Danlos syndrome
(MONDO_0020066)
Limited
KCTD1
(HGNC:18249)
scalp-ear-nipple syndrome
(MONDO_0008404)
Strong
RAX2
(HGNC:18286)
retinitis pigmentosa
(MONDO_0019200)
Moderate
TXNRD2
(HGNC:18155)
familial glucocorticoid deficiency
(MONDO_0008733)
Moderate
ASXL1
(HGNC:18318)
Bohring-Opitz syndrome
(MONDO_0011510)
Definitive
PADI3
(HGNC:18337)
uncombable hair syndrome
(MONDO_0008621)
Strong
CEBPA
(HGNC:1833)
acute myeloid leukemia
(MONDO_0018874)
Definitive
WDR19
(HGNC:18340)
cranioectodermal dysplasia
(MONDO_0009032)
Strong
ALG1
(HGNC:18294)
ALG1-congenital disorder of glycosylation
(MONDO_0012052)
Definitive
WDR19
(HGNC:18340)
ciliopathy
(MONDO_0005308)
Strong
WDR19
(HGNC:18340)
nephronophthisis 13
(MONDO_0013718)
Moderate
WDR19
(HGNC:18340)
Jeune syndrome
(MONDO_0018770)
Limited
TENT5A
(HGNC:18345)
osteogenesis imperfecta
(MONDO_0019019)
Moderate
IMPG2
(HGNC:18362)
adult-onset foveomacular vitelliform dystrophy
(MONDO_0011979)
Strong
IL17RC
(HGNC:18358)
chronic mucocutaneous candidiasis
(MONDO_0015279)
Moderate
WDR19
(HGNC:18340)
Senior-Loken syndrome
(MONDO_0017842)
Moderate
IMPG2
(HGNC:18362)
inherited retinal dystrophy
(MONDO_0019118)
Limited
IMPG2
(HGNC:18362)
retinitis pigmentosa
(MONDO_0019200)
Strong
CEBPE
(HGNC:1836)
specific granule deficiency
(MONDO_0009506)
Moderate
SMARCAD1
(HGNC:18398)
isolated congenital adermatoglyphia
(MONDO_0007619)
Strong
SMARCAD1
(HGNC:18398)
palmoplantar keratoderma-sclerodactyly syndrome
(MONDO_0008416)
Strong
ADA2
(HGNC:1839)
Sneddon syndrome
(MONDO_0008436)
Strong
HPSE2
(HGNC:18374)
Ochoa syndrome
(MONDO_0000463)
Strong
ADA2
(HGNC:1839)
Diamond-Blackfan anemia
(MONDO_0015253)
Limited
SETD2
(HGNC:18420)
Sotos syndrome
(MONDO_0019349)
Moderate
SETD2
(HGNC:18420)
Luscan-Lumish syndrome
(MONDO_0014791)
Definitive
HAVCR2
(HGNC:18437)
subcutaneous panniculitis-like T-cell lymphoma
(MONDO_0019475)
Strong
MCFD2
(HGNC:18451)
combined deficiency of factor V and factor VIII
(MONDO_0018175)
Definitive
NAXE
(HGNC:18453)
Leigh syndrome
(MONDO_0009723)
Strong
PROK2
(HGNC:18455)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
DEPDC5
(HGNC:18423)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Strong
ZDHHC5
(HGNC:18472)
schizophrenia
(MONDO_0005090)
Limited
ATP6V0A2
(HGNC:18481)
wrinkly skin syndrome
(MONDO_0010208)
Definitive
ZDHHC9
(HGNC:18475)
X-linked intellectual disability with marfanoid habitus
(MONDO_0010655)
Limited
PROK2
(HGNC:18455)
Kallmann syndrome
(MONDO_0018800)
Strong
CEL
(HGNC:1848)
maturity-onset diabetes of the young
(MONDO_0018911)
Limited
CELSR1
(HGNC:1850)
hydrops fetalis
(MONDO_0015193)
Moderate
ATP6V0A2
(HGNC:18481)
autosomal recessive cutis laxa type 2A
(MONDO_0018163)
Definitive
CEL
(HGNC:1848)
maturity-onset diabetes of the young type 8
(MONDO_0012348)
Strong
RNF43
(HGNC:18505)
hyperplastic polyposis syndrome
(MONDO_0015524)
Limited
CYS1
(HGNC:18525)
polycystic kidney disease
(MONDO_0020642)
Limited
CENPE
(HGNC:1856)
Seckel syndrome
(MONDO_0019342)
Limited
RNASEH2A
(HGNC:18518)
Aicardi-Goutieres syndrome
(MONDO_0018866)
Definitive
CENPE
(HGNC:1856)
autosomal recessive primary microcephaly
(MONDO_0016660)
Limited
CENPF
(HGNC:1857)
Stromme syndrome
(MONDO_0009477)
Moderate
NEK10
(HGNC:18592)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
CEP250
(HGNC:1859)
retinitis pigmentosa
(MONDO_0019200)
Moderate
NEK9
(HGNC:18591)
NEK9-related lethal skeletal dysplasia
(MONDO_0014870)
Limited
LRRK2
(HGNC:18618)
Parkinson disease
(MONDO_0005180)
Definitive
CPT1C
(HGNC:18540)
hereditary spastic paraplegia
(MONDO_0019064)
Limited
CPT1C
(HGNC:18540)
hereditary spastic paraplegia 73
(MONDO_0014568)
Limited
LRRK2
(HGNC:18618)
autosomal dominant Parkinson disease 8
(MONDO_0011764)
Strong
COG7
(HGNC:18622)
COG7-congenital disorder of glycosylation
(MONDO_0012118)
Moderate
COG6
(HGNC:18621)
COG6-congenital disorder of glycosylation
(MONDO_0013810)
Strong
NAA10
(HGNC:18704)
microphthalmia, syndromic 1
(MONDO_0010671)
Limited
CDK5RAP2
(HGNC:18672)
autosomal recessive primary microcephaly
(MONDO_0016660)
Strong
PMPCA
(HGNC:18667)
autosomal recessive spinocerebellar ataxia 2
(MONDO_0008943)
Limited
GRIP1
(HGNC:18708)
Fraser syndrome
(MONDO_0009046)
Moderate
DNAI2
(HGNC:18744)
primary ciliary dyskinesia
(MONDO_0016575)
Definitive
IFT27
(HGNC:18626)
Bardet-Biedl syndrome
(MONDO_0015229)
Moderate
SLURP1
(HGNC:18746)
palmoplantar keratosis
(MONDO_0006590)
Moderate
RHOBTB2
(HGNC:18756)
developmental and epileptic encephalopathy, 64
(MONDO_0033373)
Strong
SLC36A2
(HGNC:18762)
hyperglycinuria
(MONDO_0007677)
Moderate
BBS7
(HGNC:18758)
Bardet-Biedl syndrome
(MONDO_0015229)
Definitive
SLC36A2
(HGNC:18762)
iminoglycinuria
(MONDO_0009448)
Strong
ZFP57
(HGNC:18791)
transient neonatal diabetes mellitus
(MONDO_0020525)
Moderate
HPS6
(HGNC:18817)
Hermansky-Pudlak syndrome 6
(MONDO_0013558)
Strong
CAMTA1
(HGNC:18806)
cerebellar dysfunction with variable cognitive and behavioral abnormalities
(MONDO_0013886)
Strong
NDUFAF1
(HGNC:18828)
mitochondrial disease
(MONDO_0044970)
Limited
LIPI
(HGNC:18821)
hypertriglyceridemia
(MONDO_0005347)
Limited
NDUFAF1
(HGNC:18828)
mitochondrial complex I deficiency
(MONDO_0100133)
Limited
CTHRC1
(HGNC:18831)
Barrett esophagus
(MONDO_0013662)
Limited
PMPCA
(HGNC:18667)
mitochondrial disease
(MONDO_0044970)
Moderate
PPP1R13L
(HGNC:18838)
dilated cardiomyopathy
(MONDO_0005021)
Strong
CFTR
(HGNC:1884)
hereditary chronic pancreatitis
(MONDO_0008185)
Strong
CDK5RAP2
(HGNC:18672)
corpus callosum, agenesis of
(MONDO_0009022)
Limited
COG8
(HGNC:18623)
COG8-congenital disorder of glycosylation
(MONDO_0012635)
Moderate
LDLRAP1
(HGNC:18640)
homozygous familial hypercholesterolemia
(MONDO_0018328)
Strong
CFTR
(HGNC:1884)
cystic fibrosis
(MONDO_0009061)
Definitive
CFTR
(HGNC:1884)
congenital bilateral absence of vas deferens
(MONDO_0018801)
Definitive
KCNT1
(HGNC:18865)
malignant migrating partial seizures of infancy
(MONDO_0017385)
Strong
CREB3L3
(HGNC:18855)
hypertriglyceridemia
(MONDO_0005347)
Strong
KCNT1
(HGNC:18865)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Strong
MMAA
(HGNC:18871)
methylmalonic aciduria, cblA type
(MONDO_0009613)
Definitive
IFIH1
(HGNC:18873)
Singleton-Merten dysplasia
(MONDO_0008429)
Strong
IFIH1
(HGNC:18873)
Aicardi-Goutieres syndrome
(MONDO_0018866)
Definitive
IFIH1
(HGNC:18873)
Singleton-Merten syndrome 1
(MONDO_0024535)
Strong
IFIH1
(HGNC:18873)
Aicardi-Goutieres syndrome 7
(MONDO_0014367)
Moderate
TDP1
(HGNC:18884)
spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1
(MONDO_0011801)
Definitive
AP1S3
(HGNC:18971)
pustulosis palmaris et plantaris
(MONDO_0015597)
Limited
AP1S3
(HGNC:18971)
psoriasis 14, pustular
(MONDO_0013626)
Limited
MAST1
(HGNC:19034)
mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations
(MONDO_0032648)
Limited
DCXR
(HGNC:18985)
pentosuria
(MONDO_0009846)
Strong
GBA2
(HGNC:18986)
hereditary spastic paraplegia 46
(MONDO_0013737)
Moderate
THOC2
(HGNC:19073)
X-linked intellectual disability-short stature-overweight syndrome
(MONDO_0010496)
Limited
NALCN
(HGNC:19082)
Freeman-Sheldon syndrome
(MONDO_0008675)
Moderate
NALCN
(HGNC:19082)
congenital contractures of the limbs and face, hypotonia, and developmental delay
(MONDO_0014556)
Definitive
RIGI
(HGNC:19102)
Singleton-Merten dysplasia
(MONDO_0008429)
Definitive
FGD4
(HGNC:19125)
Charcot-Marie-Tooth disease type 4H
(MONDO_0012250)
Strong
NPHP4
(HGNC:19104)
Senior-Loken syndrome
(MONDO_0017842)
Moderate
PSAT1
(HGNC:19129)
Neu-Laxova syndrome
(MONDO_0000179)
Strong
RTTN
(HGNC:18654)
bilateral generalized polymicrogyria
(MONDO_0013907)
Moderate
FGD4
(HGNC:19125)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
CRB2
(HGNC:18688)
ventriculomegaly-cystic kidney disease
(MONDO_0009063)
Strong
CRB2
(HGNC:18688)
retinitis pigmentosa
(MONDO_0019200)
Limited
PSAT1
(HGNC:19129)
PSAT deficiency
(MONDO_0012596)
Moderate
PSAT1
(HGNC:19129)
neurometabolic disorder due to serine deficiency
(MONDO_0018162)
Moderate
HS6ST2
(HGNC:19133)
Paganini-Miozzo syndrome
(MONDO_0026724)
Limited
POMGNT1
(HGNC:19139)
autosomal recessive limb-girdle muscular dystrophy type 2O
(MONDO_0013161)
Limited
POMGNT1
(HGNC:19139)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Definitive
CHD1
(HGNC:1915)
Pilarowski-Bjornsson syndrome
(MONDO_0060568)
Limited
POMGNT1
(HGNC:19139)
retinitis pigmentosa
(MONDO_0019200)
Strong
KIF17
(HGNC:19167)
schizophrenia
(MONDO_0005090)
Limited
CHD1L
(HGNC:1916)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Moderate
CHD2
(HGNC:1917)
Lennox-Gastaut syndrome
(MONDO_0016532)
Limited
CHD2
(HGNC:1917)
myoclonic-astatic epilepsy
(MONDO_0016025)
Limited
KIF14
(HGNC:19181)
autosomal recessive primary microcephaly
(MONDO_0016660)
Moderate
FRAS1
(HGNC:19185)
Fraser syndrome
(MONDO_0009046)
Definitive
CHEK1
(HGNC:1925)
hereditary breast carcinoma
(MONDO_0016419)
Limited
CHD4
(HGNC:1919)
Sifrim-Hitz-Weiss syndrome
(MONDO_0014946)
Definitive
TTC5
(HGNC:19274)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Strong
MTO1
(HGNC:19261)
mitochondrial disease
(MONDO_0044970)
Strong
CHD3
(HGNC:1918)
Snijders Blok-Campeau syndrome
(MONDO_0032600)
Definitive
P3H1
(HGNC:19316)
osteogenesis imperfecta type 3
(MONDO_0009804)
Definitive
P3H1
(HGNC:19316)
osteogenesis imperfecta type 8
(MONDO_0012581)
Definitive
CHI3L1
(HGNC:1932)
schizophrenia
(MONDO_0005090)
Moderate
KIF21A
(HGNC:19349)
congenital fibrosis of extraocular muscles
(MONDO_0007614)
Strong
MMAB
(HGNC:19331)
methylmalonic aciduria, cblB type
(MONDO_0009614)
Definitive
CUX2
(HGNC:19347)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
KIF21A
(HGNC:19349)
congenital fibrosis of extraocular muscles type 1
(MONDO_0021083)
Definitive
SIN3A
(HGNC:19353)
congenital diaphragmatic hernia
(MONDO_0005711)
Moderate
CHKB
(HGNC:1938)
megaconial type congenital muscular dystrophy
(MONDO_0011246)
Definitive
SOCS1
(HGNC:19383)
autoimmune disease
(MONDO_0007179)
Strong
SOCS4
(HGNC:19392)
autoimmune disease
(MONDO_0007179)
Limited
ZMYND10
(HGNC:19412)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
CHRNA1
(HGNC:1955)
postsynaptic congenital myasthenic syndrome
(MONDO_0020344)
Limited
SBDS
(HGNC:19440)
Shwachman-Diamond syndrome
(MONDO_0009833)
Definitive
ADA
(HGNC:186)
Omenn syndrome
(MONDO_0011338)
Strong
CHRNA1
(HGNC:1955)
lethal multiple pterygium syndrome
(MONDO_0009668)
Moderate
CHRNA2
(HGNC:1956)
benign familial infantile epilepsy
(MONDO_0017615)
Limited
CHRNA4
(HGNC:1958)
sleep-related hypermotor epilepsy
(MONDO_0000030)
Moderate
CHRNA2
(HGNC:1956)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Moderate
ADAM17
(HGNC:195)
congenital heart disease
(MONDO_0005453)
Moderate
HYDIN
(HGNC:19368)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
ADAM17
(HGNC:195)
inflammatory skin and bowel disease, neonatal, 1
(MONDO_0013693)
Moderate
CHRNA4
(HGNC:1958)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Definitive
CHRNA7
(HGNC:1960)
epilepsy
(MONDO_0005027)
Moderate
CHRNB4
(HGNC:1964)
lung cancer
(MONDO_0008903)
Strong
CHRNA7
(HGNC:1960)
complex neurodevelopmental disorder
(MONDO_0100038)
Limited
SCAF4
(HGNC:19304)
Fliedner-Zweier syndrome
(MONDO_0957787)
Limited
CHRNB2
(HGNC:1962)
sleep-related hypermotor epilepsy
(MONDO_0000030)
Moderate
CHRNG
(HGNC:1967)
lethal multiple pterygium syndrome
(MONDO_0009668)
Limited
CHRNE
(HGNC:1966)
congenital myasthenic syndrome 4C
(MONDO_0012157)
Strong
CHRND
(HGNC:1965)
lethal multiple pterygium syndrome
(MONDO_0009668)
Limited
CHRNG
(HGNC:1967)
autosomal recessive multiple pterygium syndrome
(MONDO_0009926)
Strong
EIF2AK4
(HGNC:19687)
pulmonary venoocclusive disease
(MONDO_0009937)
Definitive
EIF2AK4
(HGNC:19687)
heritable pulmonary arterial hypertension
(MONDO_0017148)
Limited
NECTIN4
(HGNC:19688)
ectodermal dysplasia-syndactyly syndrome
(MONDO_0013311)
Definitive
NECTIN4
(HGNC:19688)
ectodermal dysplasia-syndactyly syndrome 1
(MONDO_0024565)
Strong
LYST
(HGNC:1968)
Chediak-Higashi syndrome
(MONDO_0008963)
Definitive
MECR
(HGNC:19691)
dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities
(MONDO_0015003)
Moderate
CHRNA2
(HGNC:1956)
sleep-related hypermotor epilepsy
(MONDO_0000030)
Limited
CNKSR2
(HGNC:19701)
intellectual disability, X-linked, syndromic, Houge type
(MONDO_0030909)
Strong
KCNV2
(HGNC:19698)
cone dystrophy with supernormal rod response
(MONDO_0012475)
Definitive
COQ4
(HGNC:19693)
mitochondrial disease
(MONDO_0044970)
Strong
ADAMTSL4
(HGNC:19706)
isolated ectopia lentis
(MONDO_0015998)
Definitive
DISP1
(HGNC:19711)
holoprosencephaly
(MONDO_0016296)
Strong
ADAMTSL4
(HGNC:19706)
ectopia lentis et pupillae
(MONDO_0009153)
Definitive
DDHD1
(HGNC:19714)
hereditary spastic paraplegia 28
(MONDO_0012256)
Moderate
DDHD1
(HGNC:19714)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
CHST3
(HGNC:1971)
spondyloepiphyseal dysplasia with congenital joint dislocations
(MONDO_0007738)
Definitive
CANT1
(HGNC:19721)
Desbuquois dysplasia 1
(MONDO_0009629)
Definitive
TNS2
(HGNC:19737)
nephrotic syndrome
(MONDO_0005377)
Moderate
POMT2
(HGNC:19743)
autosomal recessive limb-girdle muscular dystrophy type 2N
(MONDO_0013162)
Strong
POMT2
(HGNC:19743)
muscle-eye-brain disease
(MONDO_0018939)
Strong
EVC2
(HGNC:19747)
acrofacial dysostosis, Weyers type
(MONDO_0008673)
Strong
CHUK
(HGNC:1974)
cocoon syndrome
(MONDO_0013334)
Moderate
TTC7A
(HGNC:19750)
multiple intestinal atresia
(MONDO_0009465)
Definitive
VSX2
(HGNC:1975)
microphthalmia
(MONDO_0021129)
Limited
ISCA2
(HGNC:19857)
multiple mitochondrial dysfunctions syndrome 4
(MONDO_0014611)
Strong
CIT
(HGNC:1985)
autosomal recessive primary microcephaly
(MONDO_0016660)
Strong
TRAPPC4
(HGNC:19943)
neurodevelopmental disorder with epilepsy, spasticity, and brain atrophy
(MONDO_0032894)
Strong
SLC25A22
(HGNC:19954)
early myoclonic encephalopathy
(MONDO_0016022)
Strong
SLC25A22
(HGNC:19954)
malignant migrating partial seizures of infancy
(MONDO_0017385)
Strong
KIAA0586
(HGNC:19960)
Joubert syndrome
(MONDO_0018772)
Strong
KIAA0586
(HGNC:19960)
Joubert syndrome 23
(MONDO_0014664)
Moderate
TTLL5
(HGNC:19963)
cone-rod dystrophy
(MONDO_0015993)
Strong
CCDC88C
(HGNC:19967)
spinocerebellar ataxia type 40
(MONDO_0014475)
Moderate
RDH12
(HGNC:19977)
retinitis pigmentosa
(MONDO_0019200)
Moderate
RDH12
(HGNC:19977)
Leber congenital amaurosis
(MONDO_0018998)
Strong
CYCS
(HGNC:19986)
thrombocytopenia 4
(MONDO_0012775)
Strong
GREM1
(HGNC:2001)
hereditary mixed polyposis syndrome
(MONDO_0011023)
Strong
USP45
(HGNC:20080)
Leber congenital amaurosis
(MONDO_0018998)
Strong
PCSK9
(HGNC:20001)
homozygous familial hypercholesterolemia
(MONDO_0018328)
Limited
TTC8
(HGNC:20087)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
AK7
(HGNC:20091)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
AHNAK2
(HGNC:20125)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Limited
TEDC1
(HGNC:20127)
microcephaly
(MONDO_0001149)
Limited
GPR143
(HGNC:20145)
ocular albinism
(MONDO_0017304)
Definitive
SLC17A8
(HGNC:20151)
autosomal dominant nonsyndromic hearing loss 25
(MONDO_0011568)
Strong
CHD8
(HGNC:20153)
intellectual disability
(MONDO_0001071)
Strong
CHD8
(HGNC:20153)
autism
(MONDO_0005260)
Definitive
CHD8
(HGNC:20153)
congenital myasthenic syndrome
(MONDO_0018940)
Limited
CHD8
(HGNC:20153)
intellectual developmental disorder with autism and macrocephaly
(MONDO_0014017)
Definitive
HECTD1
(HGNC:20157)
neural tube defect
(MONDO_0018075)
Limited
HECTD1
(HGNC:20157)
neurodevelopmental disorder
(MONDO_0700092)
Strong
TMEM260
(HGNC:20185)
structural heart defects and renal anomalies syndrome
(MONDO_0044321)
Definitive
POLR1C
(HGNC:20194)
Treacher-Collins syndrome
(MONDO_0002457)
Moderate
SLC35C1
(HGNC:20197)
leukocyte adhesion deficiency type II
(MONDO_0009953)
Strong
CLCN1
(HGNC:2019)
myotonia congenita, autosomal recessive
(MONDO_0009715)
Moderate
B3GLCT
(HGNC:20207)
Peters plus syndrome
(MONDO_0009856)
Definitive
CLCN2
(HGNC:2020)
epilepsy
(MONDO_0005027)
Limited
CLCN4
(HGNC:2022)
intellectual disability, X-linked 49
(MONDO_0010250)
Strong
NUBPL
(HGNC:20278)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
TRIT1
(HGNC:20286)
mitochondrial disease
(MONDO_0044970)
Strong
TRIT1
(HGNC:20286)
combined oxidative phosphorylation deficiency 35
(MONDO_0054742)
Definitive
SLITRK1
(HGNC:20297)
Tourette syndrome
(MONDO_0007661)
Disputed
CLDN10
(HGNC:2033)
HELIX syndrome
(MONDO_0060564)
Strong
VIPAS39
(HGNC:20347)
arthrogryposis-renal dysfunction-cholestasis syndrome
(MONDO_0017123)
Strong
CLDN1
(HGNC:2032)
neonatal ichthyosis-sclerosing cholangitis syndrome
(MONDO_0011874)
Strong
CLDN14
(HGNC:2035)
autosomal recessive nonsyndromic hearing loss 29
(MONDO_0013537)
Limited
NDUFA11
(HGNC:20371)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFB11
(HGNC:20372)
mitochondrial disease
(MONDO_0044970)
Strong
CLDN2
(HGNC:2041)
hereditary chronic pancreatitis
(MONDO_0008185)
Limited
CLDN19
(HGNC:2040)
renal hypomagnesemia 5 with ocular involvement
(MONDO_0009548)
Strong
POLR1D
(HGNC:20422)
Treacher-Collins syndrome
(MONDO_0002457)
Definitive
SPATA7
(HGNC:20423)
retinitis pigmentosa
(MONDO_0019200)
Limited
SPATA7
(HGNC:20423)
Leber congenital amaurosis
(MONDO_0018998)
Strong
UPF3B
(HGNC:20439)
X-linked intellectual disability with marfanoid habitus
(MONDO_0010655)
Limited
POLR1B
(HGNC:20454)
Treacher-Collins syndrome
(MONDO_0002457)
Moderate
NME7
(HGNC:20461)
situs inversus
(MONDO_0010029)
Limited
BRIP1
(HGNC:20473)
familial ovarian cancer
(MONDO_0016248)
Limited
TRAF7
(HGNC:20456)
cardiac, facial, and digital anomalies with developmental delay
(MONDO_0032572)
Definitive
BRIP1
(HGNC:20473)
hereditary breast carcinoma
(MONDO_0016419)
Limited
BRIP1
(HGNC:20473)
Fanconi anemia
(MONDO_0019391)
Strong
TMC8
(HGNC:20474)
epidermodysplasia verruciformis
(MONDO_0009176)
Definitive
COA8
(HGNC:20492)
mitochondrial disease
(MONDO_0044970)
Strong
SV2A
(HGNC:20566)
epilepsy
(MONDO_0005027)
Strong
CYP26C1
(HGNC:20577)
focal facial dermal dysplasia type IV
(MONDO_0013997)
Strong
CYP2U1
(HGNC:20582)
hereditary spastic paraplegia 56
(MONDO_0014015)
Strong
CYP2U1
(HGNC:20582)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
UFM1
(HGNC:20597)
hypomyelinating leukodystrophy 6
(MONDO_0012905)
Strong
DHDDS
(HGNC:20603)
developmental delay and seizures with or without movement abnormalities
(MONDO_0044326)
Limited
DHDDS
(HGNC:20603)
retinitis pigmentosa
(MONDO_0019200)
Definitive
AIMP2
(HGNC:20609)
leukodystrophy, hypomyelinating, 17
(MONDO_0054817)
Limited
SLC24A5
(HGNC:20611)
oculocutaneous albinism type 6
(MONDO_0018264)
Moderate
MICAL1
(HGNC:20619)
epilepsy
(MONDO_0005027)
Limited
CHD7
(HGNC:20626)
CHARGE syndrome
(MONDO_0008965)
Definitive
SLC25A26
(HGNC:20661)
combined oxidative phosphorylation deficiency 28
(MONDO_0014775)
Limited
PHF8
(HGNC:20672)
syndromic X-linked intellectual disability Siderius type
(MONDO_0010286)
Strong
SLC25A24
(HGNC:20662)
Fontaine progeroid syndrome
(MONDO_0012853)
Strong
TWIST2
(HGNC:20670)
ablepharon macrostomia syndrome
(MONDO_0008693)
Strong
WDFY3
(HGNC:20751)
autism spectrum disorder
(MONDO_0005258)
Strong
CLN3
(HGNC:2074)
inherited retinal dystrophy
(MONDO_0019118)
Limited
SLC9A9
(HGNC:20653)
autism spectrum disorder
(MONDO_0005258)
Limited
SLC25A26
(HGNC:20661)
mitochondrial disease
(MONDO_0044970)
Moderate
PDLIM3
(HGNC:20767)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
PDLIM3
(HGNC:20767)
dilated cardiomyopathy
(MONDO_0005021)
Limited
ZFYVE26
(HGNC:20761)
hereditary spastic paraplegia 15
(MONDO_0010044)
Strong
CLN5
(HGNC:2076)
neuronal ceroid lipofuscinosis 5
(MONDO_0009745)
Definitive
CHD7
(HGNC:20626)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
TUBB4B
(HGNC:20771)
Leber congenital amaurosis with early-onset deafness
(MONDO_0060650)
Strong
TUBB3
(HGNC:20772)
congenital fibrosis of extraocular muscles
(MONDO_0007614)
Moderate
TUBB4A
(HGNC:20774)
torsion dystonia 4
(MONDO_0007493)
Limited
TUBB3
(HGNC:20772)
complex cortical dysplasia with other brain malformations 1
(MONDO_0013541)
Definitive
TUBB
(HGNC:20778)
multiple benign circumferential skin creases on limbs
(MONDO_0007990)
Moderate
TPP1
(HGNC:2073)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Definitive
CHD7
(HGNC:20626)
Kallmann syndrome
(MONDO_0018800)
Strong
TXNDC15
(HGNC:20652)
Meckel syndrome
(MONDO_0018921)
Limited
FANCL
(HGNC:20748)
Fanconi anemia
(MONDO_0019391)
Strong
CLN6
(HGNC:2077)
ceroid lipofuscinosis, neuronal, 6A
(MONDO_0011144)
Strong
RHBDF2
(HGNC:20788)
palmoplantar keratoderma-esophageal carcinoma syndrome
(MONDO_0007856)
Strong
CYBRD1
(HGNC:20797)
hereditary hemochromatosis
(MONDO_0006507)
Limited
CLN8
(HGNC:2079)
autism spectrum disorder
(MONDO_0005258)
Limited
CLN8
(HGNC:2079)
neuronal ceroid lipofuscinosis 8
(MONDO_0010830)
Moderate
CLN8
(HGNC:2079)
neuronal ceroid lipofuscinosis 8 northern epilepsy variant
(MONDO_0012391)
Strong
CLN8
(HGNC:2079)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Strong
SLC35D1
(HGNC:20800)
schneckenbecken dysplasia
(MONDO_0010013)
Definitive
TPCN2
(HGNC:20820)
albinism
(MONDO_0043209)
Moderate
CLPP
(HGNC:2084)
Perrault syndrome 3
(MONDO_0013588)
Strong
SLC39A14
(HGNC:20858)
hypermanganesemia with dystonia 2
(MONDO_0014864)
Limited
THAP1
(HGNC:20856)
torsion dystonia 6
(MONDO_0011264)
Definitive
SLC39A8
(HGNC:20862)
SLC39A8-CDG
(MONDO_0014746)
Definitive
PLEKHG1
(HGNC:20884)
periventricular leukomalacia
(MONDO_0015742)
Limited
BMP10
(HGNC:20869)
pulmonary arterial hypertension
(MONDO_0015924)
Moderate
GTDC1
(HGNC:20887)
neurodevelopmental disorder
(MONDO_0700092)
Limited
BCOR
(HGNC:20893)
microphthalmia, syndromic 2
(MONDO_0010261)
Definitive
POLD3
(HGNC:20932)
hearing loss disorder
(MONDO_0005365)
Moderate
SMYD1
(HGNC:20986)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
PHACTR1
(HGNC:20990)
West syndrome
(MONDO_0018097)
Strong
PHACTR1
(HGNC:20990)
developmental and epileptic encephalopathy, 70
(MONDO_0032663)
Moderate
ALPK1
(HGNC:20917)
retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and migraine headache syndrome
(MONDO_0013999)
Strong
ANTXR1
(HGNC:21014)
GAPO syndrome
(MONDO_0009263)
Strong
AARS2
(HGNC:21022)
combined oxidative phosphorylation defect type 8
(MONDO_0013570)
Strong
AARS2
(HGNC:21022)
mitochondrial disease
(MONDO_0044970)
Definitive
HACE1
(HGNC:21033)
spastic paraplegia-severe developmental delay-epilepsy syndrome
(MONDO_0014764)
Strong
NDUFAF4
(HGNC:21034)
mitochondrial complex I deficiency
(MONDO_0100133)
Limited
PITPNM3
(HGNC:21043)
cone-rod dystrophy 5
(MONDO_0010969)
Limited
PITPNM3
(HGNC:21043)
cone-rod dystrophy
(MONDO_0015993)
Limited
ERMARD
(HGNC:21056)
periventricular nodular heterotopia
(MONDO_0020341)
Limited
RSPH9
(HGNC:21057)
primary ciliary dyskinesia
(MONDO_0016575)
Definitive
SERAC1
(HGNC:21061)
Leigh syndrome
(MONDO_0009723)
Strong
FARS2
(HGNC:21062)
hereditary spastic paraplegia 77
(MONDO_0014882)
Moderate
FARS2
(HGNC:21062)
combined oxidative phosphorylation defect type 14
(MONDO_0013986)
Strong
IYD
(HGNC:21071)
familial thyroid dyshormonogenesis
(MONDO_0010132)
Limited
MIB1
(HGNC:21086)
left ventricular noncompaction
(MONDO_0018901)
Strong
ZBTB24
(HGNC:21143)
immunodeficiency-centromeric instability-facial anomalies syndrome
(MONDO_0000133)
Strong
DSE
(HGNC:21144)
Ehlers-Danlos syndrome, musculocontractural type
(MONDO_0011142)
Strong
ZBTB24
(HGNC:21143)
immunodeficiency-centromeric instability-facial anomalies syndrome 2
(MONDO_0013553)
Strong
RMND1
(HGNC:21176)
combined oxidative phosphorylation defect type 11
(MONDO_0013969)
Definitive
RMND1
(HGNC:21176)
mitochondrial disease
(MONDO_0044970)
Definitive
FA2H
(HGNC:21197)
hereditary spastic paraplegia 35
(MONDO_0012866)
Strong
WDR26
(HGNC:21208)
Skraban-Deardorff syndrome
(MONDO_0054636)
Strong
LEMD2
(HGNC:21244)
Marbach-Rustad progeroid syndrome
(MONDO_0859147)
Limited
LHFPL5
(HGNC:21253)
autosomal recessive nonsyndromic hearing loss 67
(MONDO_0012460)
Definitive
DSG4
(HGNC:21307)
monilethrix
(MONDO_0008009)
Strong
ELOVL5
(HGNC:21308)
spinocerebellar ataxia type 38
(MONDO_0014417)
Definitive
DYM
(HGNC:21317)
Smith-McCort dysplasia
(MONDO_0015799)
Limited
PDHX
(HGNC:21350)
pyruvate dehydrogenase E3-binding protein deficiency
(MONDO_0009503)
Strong
TDRD6
(HGNC:21339)
oligospermia
(MONDO_0001913)
Strong
PDHX
(HGNC:21350)
Leigh syndrome
(MONDO_0009723)
Limited
SBF2
(HGNC:2135)
Charcot-Marie-Tooth disease type 4B2
(MONDO_0011475)
Moderate
RIPPLY2
(HGNC:21390)
spondylocostal dysostosis 6, autosomal recessive
(MONDO_0014694)
Moderate
RARS2
(HGNC:21406)
mitochondrial disease
(MONDO_0044970)
Moderate
IFT74
(HGNC:21424)
Bardet-Biedl syndrome
(MONDO_0015229)
Moderate
INPP5E
(HGNC:21474)
Joubert syndrome
(MONDO_0018772)
Definitive
RFX6
(HGNC:21478)
Martinez-Frias syndrome
(MONDO_0011042)
Strong
DNAAF4
(HGNC:21493)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
KIF12
(HGNC:21495)
cholestasis
(MONDO_0001751)
Strong
ACAD9
(HGNC:21497)
acyl-CoA dehydrogenase 9 deficiency
(MONDO_0012624)
Strong
CNGA3
(HGNC:2150)
cone-rod dystrophy
(MONDO_0015993)
Strong
CNGA3
(HGNC:2150)
achromatopsia
(MONDO_0018852)
Definitive
CNGB1
(HGNC:2151)
retinitis pigmentosa
(MONDO_0019200)
Definitive
CNGB3
(HGNC:2153)
cone dystrophy
(MONDO_0000455)
Strong
CNGB3
(HGNC:2153)
achromatopsia
(MONDO_0018852)
Definitive
EYS
(HGNC:21555)
retinitis pigmentosa
(MONDO_0019200)
Definitive
RSPH4A
(HGNC:21558)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
CEP85L
(HGNC:21638)
lissencephaly 10
(MONDO_0030031)
Limited
MPC1
(HGNC:21606)
mitochondrial pyruvate carrier deficiency
(MONDO_0013877)
Strong
SATB2
(HGNC:21637)
chromosome 2q32-q33 deletion syndrome
(MONDO_0012864)
Moderate
TOPORS
(HGNC:21653)
inherited retinal dystrophy
(MONDO_0019118)
Limited
TOPORS
(HGNC:21653)
retinitis pigmentosa
(MONDO_0019200)
Strong
RSPO1
(HGNC:21679)
palmoplantar keratoderma-XX sex reversal-predisposition to squamous cell carcinoma syndrome
(MONDO_0012530)
Moderate
RNASET2
(HGNC:21686)
cystic leukoencephalopathy without megalencephaly
(MONDO_0013058)
Strong
CERKL
(HGNC:21699)
retinitis pigmentosa
(MONDO_0019200)
Definitive
ADAM9
(HGNC:216)
cone-rod dystrophy
(MONDO_0015993)
Limited
BRAT1
(HGNC:21701)
neurodevelopmental disorder with cerebellar atrophy and with or without seizures
(MONDO_0020841)
Strong
CCM2
(HGNC:21708)
famililal cerebral cavernous malformations
(MONDO_0031037)
Strong
LHX4
(HGNC:21734)
pituitary stalk interruption syndrome
(MONDO_0019828)
Moderate
CNTN4
(HGNC:2174)
autism spectrum disorder
(MONDO_0005258)
Limited
CNTN6
(HGNC:2176)
Tourette syndrome
(MONDO_0007661)
Moderate
COCH
(HGNC:2180)
autosomal dominant nonsyndromic hearing loss 9
(MONDO_0011058)
Definitive
COCH
(HGNC:2180)
nonsyndromic genetic hearing loss
(MONDO_0019497)
Strong
DYNC2I1
(HGNC:21862)
Jeune syndrome
(MONDO_0018770)
Strong
COCH
(HGNC:2180)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Strong
COL11A1
(HGNC:2186)
Marshall syndrome
(MONDO_0007949)
Strong
COL11A1
(HGNC:2186)
fibrochondrogenesis 1
(MONDO_0009226)
Limited
COL11A1
(HGNC:2186)
Stickler syndrome type 2
(MONDO_0011493)
Definitive
COL11A1
(HGNC:2186)
fibrochondrogenesis
(MONDO_0016068)
Moderate
RINT1
(HGNC:21876)
breast cancer
(MONDO_0007254)
Disputed
COL11A2
(HGNC:2187)
fibrochondrogenesis
(MONDO_0016068)
Limited
RINT1
(HGNC:21876)
hereditary breast carcinoma
(MONDO_0016419)
Refuted
IFT56
(HGNC:21882)
biliary, renal, neurologic, and skeletal syndrome
(MONDO_0859191)
Limited
COL12A1
(HGNC:2188)
Bethlem myopathy
(MONDO_0008029)
Strong
COL12A1
(HGNC:2188)
Ullrich congenital muscular dystrophy
(MONDO_0000355)
Limited
COL12A1
(HGNC:2188)
Bethlem myopathy 2
(MONDO_0034022)
Strong
ADAMTS2
(HGNC:218)
Ehlers-Danlos syndrome, dermatosparaxis type
(MONDO_0009161)
Strong
COL17A1
(HGNC:2194)
epithelial recurrent erosion dystrophy
(MONDO_0007381)
Strong
COL17A1
(HGNC:2194)
amelogenesis imperfecta
(MONDO_0019507)
Strong
COL1A2
(HGNC:2198)
osteogenesis imperfecta type 4
(MONDO_0008148)
Moderate
COL1A2
(HGNC:2198)
osteogenesis imperfecta
(MONDO_0019019)
Definitive
ADAMTS3
(HGNC:219)
Hennekam syndrome
(MONDO_0016256)
Limited
COL1A1
(HGNC:2197)
Ehlers-Danlos syndrome
(MONDO_0020066)
Definitive
COL1A1
(HGNC:2197)
osteogenesis imperfecta type 1
(MONDO_0008146)
Definitive
ADAMTS3
(HGNC:219)
hennekam lymphangiectasia-lymphedema syndrome 3
(MONDO_0032564)
Limited
COL2A1
(HGNC:2200)
Stickler syndrome type 1
(MONDO_0007160)
Definitive
COL2A1
(HGNC:2200)
Legg-Calve-Perthes disease
(MONDO_0007885)
Disputed
COL2A1
(HGNC:2200)
platyspondylic dysplasia, Torrance type
(MONDO_0007895)
Moderate
COL2A1
(HGNC:2200)
Kniest dysplasia
(MONDO_0007987)
Definitive
COL2A1
(HGNC:2200)
spondyloepiphyseal dysplasia congenita
(MONDO_0008471)
Definitive
COL2A1
(HGNC:2200)
spondylometaphyseal dysplasia, Schmidt type
(MONDO_0008478)
Limited
COL2A1
(HGNC:2200)
achondrogenesis type II
(MONDO_0008702)
Strong
COL2A1
(HGNC:2200)
spondyloepiphyseal dysplasia with metatarsal shortening
(MONDO_0012206)
Strong
COL2A1
(HGNC:2200)
mild spondyloepiphyseal dysplasia due to COL2A1 mutation with early-onset osteoarthritis
(MONDO_0011496)
Strong
COL2A1
(HGNC:2200)
spondyloperipheral dysplasia
(MONDO_0010078)
Strong
COL1A1
(HGNC:2197)
osteogenesis imperfecta type 2
(MONDO_0008147)
Moderate
KCTD7
(HGNC:21957)
progressive myoclonic epilepsy type 3
(MONDO_0012721)
Strong
COL1A1
(HGNC:2197)
osteogenesis imperfecta type 4
(MONDO_0008148)
Strong
COL1A1
(HGNC:2197)
Caffey disease
(MONDO_0007244)
Definitive
KCTD7
(HGNC:21957)
progressive myoclonus epilepsy
(MONDO_0020074)
Definitive
COL18A1
(HGNC:2195)
Knobloch syndrome 1
(MONDO_0800167)
Strong
COL1A1
(HGNC:2197)
Ehlers-Danlos syndrome, classic type
(MONDO_0007522)
Strong
COL2A1
(HGNC:2200)
otospondylomegaepiphyseal dysplasia, autosomal recessive
(MONDO_0044206)
Limited
COL2A1
(HGNC:2200)
spondylometaphyseal dysplasia
(MONDO_0016763)
Refuted
COL1A2
(HGNC:2198)
osteogenesis imperfecta type 1
(MONDO_0008146)
Definitive
COL2A1
(HGNC:2200)
autosomal dominant rhegmatogenous retinal detachment
(MONDO_0016202)
Moderate
COL4A1
(HGNC:2202)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Limited
COL3A1
(HGNC:2201)
Ehlers-Danlos syndrome, vascular type
(MONDO_0017314)
Definitive
COL2A1
(HGNC:2200)
avascular necrosis of femoral head, primary, 1
(MONDO_0054550)
Strong
COL4A1
(HGNC:2202)
autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome
(MONDO_0012726)
Strong
COL1A2
(HGNC:2198)
osteogenesis imperfecta type 2
(MONDO_0008147)
Moderate
COL4A1
(HGNC:2202)
microangiopathy and leukoencephalopathy, pontine, autosomal dominant
(MONDO_0032814)
Strong
COL4A1
(HGNC:2202)
familial porencephaly
(MONDO_0020496)
Definitive
COL4A2
(HGNC:2203)
familial porencephaly
(MONDO_0020496)
Strong
COL4A3
(HGNC:2204)
autosomal dominant Alport syndrome
(MONDO_0007086)
Definitive
COL4A3
(HGNC:2204)
autosomal recessive Alport syndrome
(MONDO_0008762)
Definitive
COL2A1
(HGNC:2200)
dysspondyloenchondromatosis
(MONDO_0019412)
Moderate
COL2A1
(HGNC:2200)
hypochondrogenesis
(MONDO_0019669)
Limited
COL4A3
(HGNC:2204)
Alport syndrome
(MONDO_0018965)
Definitive
COL4A4
(HGNC:2206)
autosomal dominant Alport syndrome
(MONDO_0007086)
Strong
COL4A4
(HGNC:2206)
autosomal recessive Alport syndrome
(MONDO_0008762)
Strong
COL4A4
(HGNC:2206)
Alport syndrome
(MONDO_0018965)
Strong
COL4A5
(HGNC:2207)
Alport syndrome
(MONDO_0018965)
Definitive
COL4A5
(HGNC:2207)
X-linked Alport syndrome
(MONDO_0010520)
Definitive
COL4A6
(HGNC:2208)
X-linked nonsyndromic hearing loss
(MONDO_0019586)
Limited
COL5A2
(HGNC:2210)
Ehlers-Danlos syndrome, classic type
(MONDO_0007522)
Definitive
COL5A2
(HGNC:2210)
Ehlers-Danlos syndrome
(MONDO_0020066)
Strong
COL6A2
(HGNC:2212)
Ullrich congenital muscular dystrophy 1A
(MONDO_0009681)
Strong
COL7A1
(HGNC:2214)
transient bullous dermolysis of the newborn
(MONDO_0007548)
Strong
COL7A1
(HGNC:2214)
recessive dystrophic epidermolysis bullosa
(MONDO_0009179)
Definitive
COL7A1
(HGNC:2214)
dystrophic epidermolysis bullosa pruriginosa
(MONDO_0011398)
Strong
COL7A1
(HGNC:2214)
dystrophic epidermolysis bullosa, nails only
(MONDO_0015553)
Limited
COL7A1
(HGNC:2214)
recessive dystrophic epidermolysis bullosa inversa
(MONDO_0019310)
Moderate
COL8A2
(HGNC:2216)
Fuchs' endothelial dystrophy
(MONDO_0005321)
Definitive
COL8A2
(HGNC:2216)
posterior polymorphous corneal dystrophy
(MONDO_0020364)
Disputed
COL9A1
(HGNC:2217)
Stickler syndrome
(MONDO_0019354)
Strong
COL9A2
(HGNC:2218)
Stickler syndrome
(MONDO_0019354)
Strong
AP5Z1
(HGNC:22197)
hereditary spastic paraplegia 48
(MONDO_0013342)
Limited
COL9A3
(HGNC:2219)
Stickler syndrome
(MONDO_0019354)
Strong
COL7A1
(HGNC:2214)
pretibial dystrophic epidermolysis bullosa
(MONDO_0007552)
Moderate
COLEC10
(HGNC:2220)
3MC syndrome
(MONDO_0017398)
Strong
COLEC10
(HGNC:2220)
3MC syndrome 3
(MONDO_0009554)
Strong
KIAA1549
(HGNC:22219)
retinitis pigmentosa
(MONDO_0019200)
Limited
COMP
(HGNC:2227)
multiple epiphyseal dysplasia type 1
(MONDO_0007561)
Moderate
CORO1A
(HGNC:2252)
severe combined immunodeficiency due to CORO1A deficiency
(MONDO_0014168)
Strong
COX10
(HGNC:2260)
Leigh syndrome
(MONDO_0009723)
Strong
COX10
(HGNC:2260)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Strong
COX10
(HGNC:2260)
mitochondrial disease
(MONDO_0044970)
Moderate
COX15
(HGNC:2263)
Leigh syndrome
(MONDO_0009723)
Moderate
COX5A
(HGNC:2267)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Limited
COX4I1
(HGNC:2265)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Limited
GMPPA
(HGNC:22923)
alacrima, achalasia, and intellectual disability syndrome
(MONDO_0014219)
Strong
GMPPA
(HGNC:22923)
triple-A syndrome
(MONDO_0009279)
Refuted
GMPPB
(HGNC:22932)
autosomal recessive limb-girdle muscular dystrophy type 2T
(MONDO_0014142)
Strong
COX8A
(HGNC:2294)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Limited
POGLUT1
(HGNC:22954)
Dowling-Degos disease
(MONDO_0008371)
Strong
MED13L
(HGNC:22962)
syndromic intellectual disability
(MONDO_0000508)
Strong
POGLUT1
(HGNC:22954)
autosomal recessive limb-girdle muscular dystrophy type 2R1
(MONDO_0014977)
Strong
MED13L
(HGNC:22962)
congenital heart disease
(MONDO_0005453)
Strong
PEX26
(HGNC:22965)
Zellweger spectrum disorders
(MONDO_0019609)
Strong
CPA1
(HGNC:2296)
hereditary chronic pancreatitis
(MONDO_0008185)
Moderate
FAM20B
(HGNC:23017)
Desbuquois dysplasia
(MONDO_0015426)
Limited
FAM20A
(HGNC:23015)
amelogenesis imperfecta type 1G
(MONDO_0008771)
Definitive
COL27A1
(HGNC:22986)
Steel syndrome
(MONDO_0014061)
Definitive
GMPPB
(HGNC:22932)
congenital myasthenic syndrome
(MONDO_0018940)
Definitive
NLRP7
(HGNC:22947)
complete hydatidiform mole
(MONDO_0016785)
Definitive
CPE
(HGNC:2303)
BDV syndrome
(MONDO_0859150)
Strong
PDSS2
(HGNC:23041)
Leigh syndrome
(MONDO_0009723)
Limited
LMBRD1
(HGNC:23038)
methylmalonic aciduria and homocystinuria type cblF
(MONDO_0010183)
Strong
SLC10A7
(HGNC:23088)
short stature, amelogenesis imperfecta, and skeletal dysplasia with scoliosis
(MONDO_0032703)
Definitive
SLC13A5
(HGNC:23089)
amelocerebrohypohidrotic syndrome
(MONDO_0009185)
Strong
SLC29A3
(HGNC:23096)
dysosteosclerosis
(MONDO_0009138)
Limited
FAT4
(HGNC:23109)
Hennekam syndrome
(MONDO_0016256)
Strong
SLC13A5
(HGNC:23089)
developmental and epileptic encephalopathy, 25
(MONDO_0014392)
Strong
CPN1
(HGNC:2312)
carboxypeptidase N deficiency
(MONDO_0008910)
Limited
UNC13D
(HGNC:23147)
familial hemophagocytic lymphohistiocytosis 3
(MONDO_0012146)
Definitive
FAT4
(HGNC:23109)
van Maldergem syndrome
(MONDO_0017813)
Strong
ALG2
(HGNC:23159)
ALG2-congenital disorder of glycosylation
(MONDO_0011933)
Strong
ALG8
(HGNC:23161)
ALG8-congenital disorder of glycosylation
(MONDO_0011969)
Strong
PNPT1
(HGNC:23166)
hearing loss disorder
(MONDO_0005365)
Moderate
PNPT1
(HGNC:23166)
Leigh syndrome
(MONDO_0009723)
Moderate
PNPT1
(HGNC:23166)
spinocerebellar ataxia type 25
(MONDO_0012103)
Limited
PNPT1
(HGNC:23166)
combined oxidative phosphorylation defect type 13
(MONDO_0013977)
Limited
FANCM
(HGNC:23168)
breast cancer
(MONDO_0007254)
Strong
FANCM
(HGNC:23168)
Fanconi anemia
(MONDO_0019391)
Limited
PIGW
(HGNC:23213)
hyperphosphatasia with intellectual disability syndrome 5
(MONDO_0014457)
Strong
PIGO
(HGNC:23215)
hyperphosphatasia-intellectual disability syndrome
(MONDO_0016596)
Moderate
CPOX
(HGNC:2321)
harderoporphyria
(MONDO_0030048)
Strong
SPATA13
(HGNC:23222)
primary angle-closure glaucoma
(MONDO_0001868)
Moderate
MYPN
(HGNC:23246)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
UBA5
(HGNC:23230)
developmental and epileptic encephalopathy, 44
(MONDO_0014933)
Definitive
MYPN
(HGNC:23246)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
MYPN
(HGNC:23246)
cap myopathy
(MONDO_0015753)
Moderate
ETHE1
(HGNC:23287)
Leigh syndrome
(MONDO_0009723)
Limited
HKDC1
(HGNC:23302)
retinitis pigmentosa
(MONDO_0019200)
Moderate
A2ML1
(HGNC:23336)
Noonan syndrome
(MONDO_0018997)
Disputed
PXK
(HGNC:23326)
systemic lupus erythematosus
(MONDO_0007915)
Disputed
CR2
(HGNC:2336)
systemic lupus erythematosus
(MONDO_0007915)
Limited
CR2
(HGNC:2336)
common variable immunodeficiency
(MONDO_0015517)
Limited
FREM1
(HGNC:23399)
oculotrichoanal syndrome
(MONDO_0009560)
Strong
FREM1
(HGNC:23399)
BNAR syndrome
(MONDO_0012165)
Moderate
LRMDA
(HGNC:23405)
oculocutaneous albinism type 7
(MONDO_0014070)
Moderate
DOLK
(HGNC:23406)
DK1-congenital disorder of glycosylation
(MONDO_0012556)
Moderate
CRADD
(HGNC:2340)
intellectual disability, autosomal recessive 34
(MONDO_0013785)
Strong
CRB1
(HGNC:2343)
nanophthalmia
(MONDO_0005514)
Limited
CRB1
(HGNC:2343)
Leber congenital amaurosis 8
(MONDO_0013453)
Limited
CRB1
(HGNC:2343)
pigmented paravenous retinochoroidal atrophy
(MONDO_0008246)
Limited
CRB1
(HGNC:2343)
Leber congenital amaurosis
(MONDO_0018998)
Definitive
CRB1
(HGNC:2343)
retinitis pigmentosa
(MONDO_0019200)
Definitive
DOCK11
(HGNC:23483)
autoinflammatory disease, multisystem, with immune dysregulation, X-linked
(MONDO_0957494)
Strong
CREBBP
(HGNC:2348)
Rubinstein-Taybi syndrome due to CREBBP mutations
(MONDO_0008393)
Strong
CREBBP
(HGNC:2348)
Rubinstein-Taybi syndrome
(MONDO_0019188)
Definitive
CRH
(HGNC:2355)
autosomal dominant nocturnal frontal lobe epilepsy
(MONDO_0020300)
Limited
DHTKD1
(HGNC:23537)
2-aminoadipic 2-oxoadipic aciduria
(MONDO_0008774)
Strong
MORC2
(HGNC:23573)
Leigh syndrome
(MONDO_0009723)
Limited
ANKRD17
(HGNC:23575)
Chopra-Amiel-Gordon syndrome
(MONDO_0859186)
Strong
VPS13D
(HGNC:23595)
Leigh syndrome
(MONDO_0009723)
Limited
VPS13D
(HGNC:23595)
autosomal recessive cerebellar ataxia-saccadic intrusion syndrome
(MONDO_0011811)
Strong
VPS13C
(HGNC:23594)
young-onset Parkinson disease
(MONDO_0017279)
Moderate
SKIC3
(HGNC:23639)
trichohepatoenteric syndrome
(MONDO_0009105)
Definitive
CRKL
(HGNC:2363)
congenital heart disease
(MONDO_0005453)
Limited
CRLF1
(HGNC:2364)
Cold-induced sweating syndrome 1
(MONDO_0010091)
Definitive
CRLF1
(HGNC:2364)
cold-induced sweating syndrome
(MONDO_0015526)
Strong
GNE
(HGNC:23657)
sialuria
(MONDO_0010028)
Limited
GPR161
(HGNC:23694)
pituitary stalk interruption syndrome
(MONDO_0019828)
Limited
ADCY5
(HGNC:236)
neurodevelopmental disorder
(MONDO_0700092)
Limited
TTC12
(HGNC:23700)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
PGAP3
(HGNC:23719)
hyperphosphatasia with intellectual disability syndrome 4
(MONDO_0014318)
Strong
PTF1A
(HGNC:23734)
pancreatic agenesis
(MONDO_0009832)
Strong
PGAP3
(HGNC:23719)
hyperphosphatasia-intellectual disability syndrome
(MONDO_0016596)
Strong
PTF1A
(HGNC:23734)
permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome
(MONDO_0012192)
Moderate
PTF1A
(HGNC:23734)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Moderate
MED27
(HGNC:2377)
neurodevelopmental disorder with spasticity, cataracts, and cerebellar hypoplasia
(MONDO_0859137)
Limited
PIKFYVE
(HGNC:23785)
fleck corneal dystrophy
(MONDO_0007376)
Limited
CRTAP
(HGNC:2379)
osteogenesis imperfecta type 3
(MONDO_0009804)
Moderate
PACS2
(HGNC:23794)
developmental and epileptic encephalopathy, 66
(MONDO_0054845)
Strong
CRTAP
(HGNC:2379)
osteogenesis imperfecta type 7
(MONDO_0012536)
Limited
ADCY6
(HGNC:237)
lethal congenital contracture syndrome 8
(MONDO_0014570)
Strong
CRX
(HGNC:2383)
retinitis pigmentosa
(MONDO_0019200)
Strong
ASXL2
(HGNC:23805)
Shashi-Pena syndrome
(MONDO_0014963)
Strong
SLX4
(HGNC:23845)
hereditary breast carcinoma
(MONDO_0016419)
Limited
CRYAB
(HGNC:2389)
fatal infantile hypertonic myofibrillar myopathy
(MONDO_0013472)
Limited
SLX4
(HGNC:23845)
Fanconi anemia
(MONDO_0019391)
Strong
ABAT
(HGNC:23)
GABA aminotransaminase deficiency
(MONDO_0013166)
Moderate
APPL1
(HGNC:24035)
maturity-onset diabetes of the young type 14
(MONDO_0014674)
Limited
APPL1
(HGNC:24035)
maturity-onset diabetes of the young
(MONDO_0018911)
Limited
CLMP
(HGNC:24039)
congenital short bowel syndrome
(MONDO_0014097)
Strong
ADIPOR1
(HGNC:24040)
retinitis pigmentosa
(MONDO_0019200)
Moderate
KNL1
(HGNC:24054)
autosomal recessive primary microcephaly
(MONDO_0016660)
Definitive
GALM
(HGNC:24063)
galactosemia 4
(MONDO_0030105)
Definitive
SORBS2
(HGNC:24098)
congenital heart disease
(MONDO_0005453)
Limited
RNASEH2C
(HGNC:24116)
Aicardi-Goutieres syndrome
(MONDO_0018866)
Definitive
B9D1
(HGNC:24123)
Joubert syndrome
(MONDO_0018772)
Limited
B9D1
(HGNC:24123)
Meckel syndrome
(MONDO_0018921)
Limited
PHF21A
(HGNC:24156)
intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without seizures
(MONDO_0032883)
Strong
BRCC3
(HGNC:24185)
Moyamoya disease
(MONDO_0016820)
Moderate
FAM111B
(HGNC:24200)
hereditary sclerosing poikiloderma with tendon and pulmonary involvement
(MONDO_0014310)
Strong
CISD2
(HGNC:24212)
Wolfram syndrome 2
(MONDO_0011502)
Strong
CISD2
(HGNC:24212)
Wolfram syndrome
(MONDO_0018105)
Strong
GLYCTK
(HGNC:24247)
D-glyceric aciduria
(MONDO_0009070)
Strong
YARS2
(HGNC:24249)
myopathy, lactic acidosis, and sideroblastic anemia
(MONDO_0000863)
Definitive
YARS2
(HGNC:24249)
myopathy, lactic acidosis, and sideroblastic anemia 2
(MONDO_0013307)
Definitive
ASCC1
(HGNC:24268)
spinal muscular atrophy with congenital bone fractures 2
(MONDO_0014807)
Moderate
PTRH2
(HGNC:24265)
neurologic, endocrine, and pancreatic disease, multisystem, infantile-onset 1
(MONDO_8000012)
Strong
CARTPT
(HGNC:24323)
inherited obesity
(MONDO_0019182)
Limited
OTUD6B
(HGNC:24281)
intellectual developmental disorder with dysmorphic facies, seizures, and distal limb anomalies
(MONDO_0044319)
Strong
CSF1R
(HGNC:2433)
brain abnormalities, neurodegeneration, and dysosteosclerosis
(MONDO_0032772)
Moderate
CSF2RB
(HGNC:2436)
hereditary pulmonary alveolar proteinosis
(MONDO_0012580)
Limited
CSF2RA
(HGNC:2435)
hereditary pulmonary alveolar proteinosis
(MONDO_0012580)
Limited
CSF3R
(HGNC:2439)
hereditary neutrophilia
(MONDO_0008092)
Limited
DMGDH
(HGNC:24475)
dimethylglycine dehydrogenase deficiency
(MONDO_0011610)
Limited
BOLA3
(HGNC:24415)
multiple mitochondrial dysfunctions syndrome 2
(MONDO_0013675)
Strong
MMACHC
(HGNC:24525)
methylmalonic aciduria and homocystinuria type cblC
(MONDO_0010184)
Definitive
TCTN3
(HGNC:24519)
orofaciodigital syndrome IV
(MONDO_0009794)
Limited
ATL3
(HGNC:24526)
hereditary sensory and autonomic neuropathy type 1
(MONDO_0018213)
Strong
WDR62
(HGNC:24502)
microcephaly 2, primary, autosomal recessive, with or without cortical malformations
(MONDO_0011435)
Definitive
TCTN3
(HGNC:24519)
ciliopathy
(MONDO_0005308)
Limited
CHMP2B
(HGNC:24537)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
CHMP2B
(HGNC:24537)
frontotemporal dementia and/or amyotrophic lateral sclerosis 7
(MONDO_0010936)
Definitive
C2CD3
(HGNC:24564)
orofaciodigital syndrome type 14
(MONDO_0014413)
Strong
KANSL1
(HGNC:24565)
Koolen-de Vries syndrome
(MONDO_0012496)
Definitive
CDT1 Gene
(HGNC:24576)
Meier-Gorlin syndrome
(MONDO_0016817)
Strong
DYNC2LI1
(HGNC:24595)
Ellis-van Creveld syndrome
(MONDO_0009162)
Strong
HYCC1
(HGNC:24587)
hypomyelinating leukodystrophy 5
(MONDO_0012514)
Definitive
CSNK2B
(HGNC:2460)
Poirier-Bienvenu neurodevelopmental syndrome
(MONDO_0032889)
Definitive
ANKS1B
(HGNC:24600)
neurodevelopmental disorder
(MONDO_0700092)
Limited
DYNC2LI1
(HGNC:24595)
short-rib thoracic dysplasia 15 with polydactyly
(MONDO_0014907)
Strong
CFHR5
(HGNC:24668)
C3 glomerulonephritis
(MONDO_0013892)
Limited
SMC3
(HGNC:2468)
Cornelia de Lange syndrome
(MONDO_0016033)
Strong
EPS15L1
(HGNC:24634)
split hand-foot malformation
(MONDO_0016576)
Limited
NRROS
(HGNC:24613)
seizures, early-onset, with neurodegeneration and brain calcifications
(MONDO_0030033)
Moderate
CSRP3
(HGNC:2472)
dilated cardiomyopathy
(MONDO_0005021)
Limited
SIL1
(HGNC:24624)
Marinesco-Sjogren syndrome
(MONDO_0009567)
Definitive
VPS35L
(HGNC:24641)
Ritscher-Schinzel syndrome
(MONDO_0019078)
Moderate
EHMT1
(HGNC:24650)
Kleefstra syndrome 1
(MONDO_0027407)
Definitive
QRICH1
(HGNC:24713)
Ververi-Brady syndrome
(MONDO_0060707)
Strong
FAM111A
(HGNC:24725)
autosomal dominant Kenny-Caffey syndrome
(MONDO_0007478)
Definitive
CSRP3
(HGNC:2472)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
NHLRC2
(HGNC:24731)
fibrosis, neurodegeneration, and cerebral angiomatosis
(MONDO_0032651)
Strong
FAM111A
(HGNC:24725)
osteocraniostenosis
(MONDO_0011215)
Strong
CST3
(HGNC:2475)
ACys amyloidosis
(MONDO_0007098)
Strong
LRIT3
(HGNC:24783)
congenital stationary night blindness
(MONDO_0016293)
Limited
ZNF699
(HGNC:24750)
DEGCAGS syndrome
(MONDO_0859181)
Limited
CSTA
(HGNC:2481)
acral peeling skin syndrome
(MONDO_0012345)
Moderate
CSTA
(HGNC:2481)
exfoliative ichthyosis
(MONDO_0017339)
Limited
GAS2L2
(HGNC:24846)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
MFF
(HGNC:24858)
Leigh syndrome
(MONDO_0009723)
Limited
MFF
(HGNC:24858)
encephalopathy due to defective mitochondrial and peroxisomal fission 2
(MONDO_0014905)
Limited
MOGS
(HGNC:24862)
MOGS-congenital disorder of glycosylation
(MONDO_0011629)
Strong
NKX2-5
(HGNC:2488)
dilated cardiomyopathy
(MONDO_0005021)
Limited
NKX2-5
(HGNC:2488)
tetralogy of fallot
(MONDO_0008542)
Limited
ZC4H2
(HGNC:24931)
Wieacker-Wolff syndrome, female-restricted
(MONDO_0026762)
Limited
CTBP1
(HGNC:2494)
hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome
(MONDO_0060666)
Strong
NPRL2
(HGNC:24969)
familial focal epilepsy with variable foci
(MONDO_0020310)
Limited
NPRL2
(HGNC:24969)
focal epilepsy
(MONDO_0005384)
Strong
COA3
(HGNC:24990)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Limited
CCN2
(HGNC:2500)
kyphomelic dysplasia
(MONDO_0008881)
Strong
CCN2
(HGNC:2500)
spondyloepimetaphyseal dysplasia
(MONDO_0100510)
Strong
TMEM216
(HGNC:25018)
Joubert syndrome 2
(MONDO_0011963)
Strong
TMEM216
(HGNC:25018)
Meckel syndrome
(MONDO_0018921)
Strong
CTLA4
(HGNC:2505)
systemic lupus erythematosus
(MONDO_0007915)
Strong
ACD
(HGNC:25070)
Hoyeraal-Hreidarsson syndrome
(MONDO_0018045)
Limited
CTLA4
(HGNC:2505)
autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency
(MONDO_0014493)
Definitive
BOD1
(HGNC:25114)
intellectual disability
(MONDO_0001071)
Limited
CTNNA3
(HGNC:2511)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
MTSS2
(HGNC:25094)
intellectual developmental disorder with ocular anomalies and distinctive facial features
(MONDO_0859303)
Strong
MARS2
(HGNC:25133)
spastic ataxia 3
(MONDO_0012664)
Limited
MARS2
(HGNC:25133)
combined oxidative phosphorylation defect type 25
(MONDO_0014636)
Limited
PKDCC
(HGNC:25123)
rhizomelic limb shortening with dysmorphic features
(MONDO_0032935)
Limited
MARS2
(HGNC:25133)
mitochondrial disease
(MONDO_0044970)
Limited
LRSAM1
(HGNC:25135)
Charcot-Marie-Tooth disease axonal type 2P
(MONDO_0013753)
Strong
CTNNB1
(HGNC:2514)
severe intellectual disability-progressive spastic diplegia syndrome
(MONDO_0014035)
Definitive
HOGA1
(HGNC:25155)
primary hyperoxaluria type 3
(MONDO_0013327)
Definitive
CTNNB1
(HGNC:2514)
exudative vitreoretinopathy
(MONDO_0019516)
Strong
CTNND2
(HGNC:2516)
neurodevelopmental disorder
(MONDO_0700092)
Limited
CTNND1
(HGNC:2515)
blepharocheilodontic syndrome
(MONDO_0007339)
Strong
CTNS
(HGNC:2518)
ocular cystinosis
(MONDO_0009064)
Strong
CTNS
(HGNC:2518)
juvenile nephropathic cystinosis
(MONDO_0009066)
Definitive
CTNS
(HGNC:2518)
nephropathic infantile cystinosis
(MONDO_0018467)
Definitive
SLC25A46
(HGNC:25198)
Leigh syndrome
(MONDO_0009723)
Limited
SLC25A46
(HGNC:25198)
pontocerebellar hypoplasia type 1
(MONDO_0016396)
Limited
MMADHC
(HGNC:25221)
methylmalonic aciduria and homocystinuria type cblD
(MONDO_0010185)
Strong
COQ2
(HGNC:25223)
multiple system atrophy
(MONDO_0007803)
Limited
SGSM3
(HGNC:25228)
neurodevelopmental disorder
(MONDO_0700092)
Strong
CCDC39
(HGNC:25244)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
CTRC
(HGNC:2523)
hereditary chronic pancreatitis
(MONDO_0008185)
Strong
CTSB
(HGNC:2527)
keratolytic winter erythema
(MONDO_0007854)
Refuted
ODAD4
(HGNC:25280)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
TLCD3B
(HGNC:25295)
cone-rod dystrophy
(MONDO_0015993)
Strong
CTSD
(HGNC:2529)
neuronal ceroid lipofuscinosis 10
(MONDO_0012414)
Limited
CTSD
(HGNC:2529)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Strong
CTSF
(HGNC:2531)
adult neuronal ceroid lipofuscinosis
(MONDO_0019260)
Strong
C3orf20
(HGNC:25320)
neuromyelitis optica
(MONDO_0019100)
Limited
SLC30A10
(HGNC:25355)
cirrhosis - dystonia - polycythemia - hypermanganesemia syndrome
(MONDO_0013208)
Moderate
CCDC8
(HGNC:25367)
3-M syndrome
(MONDO_0007477)
Limited
FREM2
(HGNC:25396)
Fraser syndrome
(MONDO_0009046)
Definitive
ADH5
(HGNC:253)
AMED syndrome, digenic
(MONDO_0030894)
Strong
OTUD5
(HGNC:25402)
multiple congenital anomalies-neurodevelopmental syndrome, X-linked
(MONDO_0025351)
Moderate
SASS6
(HGNC:25403)
autosomal recessive primary microcephaly
(MONDO_0016660)
Limited
ZWILCH
(HGNC:25468)
autism spectrum disorder
(MONDO_0005258)
Limited
TRMU
(HGNC:25481)
mitochondrial myopathy with reversible cytochrome C oxidase deficiency
(MONDO_0010780)
Limited
TRMU
(HGNC:25481)
Leigh syndrome
(MONDO_0009723)
Limited
LRRC56
(HGNC:25430)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
TSR2
(HGNC:25455)
Diamond-Blackfan anemia
(MONDO_0015253)
Limited
MTPAP
(HGNC:25532)
mitochondrial disease
(MONDO_0044970)
Limited
VAC14
(HGNC:25507)
Yunis-Varon syndrome
(MONDO_0008995)
Limited
TRMU
(HGNC:25481)
acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins
(MONDO_0013111)
Moderate
CUBN
(HGNC:2548)
Imerslund-Grasbeck syndrome
(MONDO_0009853)
Strong
DARS2
(HGNC:25538)
mitochondrial disease
(MONDO_0044970)
Strong
CUL3
(HGNC:2553)
neurodevelopmental disorder with or without autism or seizures
(MONDO_0030994)
Strong
SETD5
(HGNC:25566)
intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency
(MONDO_0014336)
Moderate
VPS53
(HGNC:25608)
pontocerebellar hypoplasia type 2E
(MONDO_0014370)
Limited
NAXD
(HGNC:25576)
NAD(P)HX dehydratase deficiency
(MONDO_0034121)
Strong
CWF19L1
(HGNC:25613)
autosomal recessive spinocerebellar ataxia 17
(MONDO_0014503)
Strong
ODAD2
(HGNC:25583)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
ARL13B
(HGNC:25419)
Joubert syndrome
(MONDO_0018772)
Strong
WRAP53
(HGNC:25522)
dyskeratosis congenita
(MONDO_0015780)
Strong
TBC1D23
(HGNC:25622)
pontocerebellar hypoplasia, type 11
(MONDO_0054669)
Limited
TTC21B
(HGNC:25660)
nephronophthisis 12
(MONDO_0013442)
Moderate
ANO10
(HGNC:25519)
autosomal recessive spinocerebellar ataxia 10
(MONDO_0013392)
Limited
BCORL1
(HGNC:25657)
Shukla-Vernon syndrome
(MONDO_0026727)
Limited
CCDC88A
(HGNC:25523)
PEHO-like syndrome
(MONDO_0020495)
Limited
AAGAB
(HGNC:25662)
punctate palmoplantar keratoderma type 1
(MONDO_0019332)
Definitive
RNASEH2B
(HGNC:25671)
prostate cancer
(MONDO_0008315)
Limited
RNASEH2B
(HGNC:25671)
Aicardi-Goutieres syndrome 2
(MONDO_0012429)
Limited
RNASEH2B
(HGNC:25671)
Aicardi-Goutieres syndrome
(MONDO_0018866)
Definitive
OFD1
(HGNC:2567)
Simpson-Golabi-Behmel syndrome type 2
(MONDO_0010265)
Limited
CXCR4
(HGNC:2561)
WHIM syndrome
(MONDO_0023880)
Definitive
OFD1
(HGNC:2567)
retinitis pigmentosa 23
(MONDO_0010320)
Limited
OFD1
(HGNC:2567)
Joubert syndrome 10
(MONDO_0010431)
Strong
OFD1
(HGNC:2567)
orofaciodigital syndrome I
(MONDO_0010702)
Definitive
OFD1
(HGNC:2567)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
OFD1
(HGNC:2567)
retinitis pigmentosa
(MONDO_0019200)
Limited
CARS2
(HGNC:25695)
combined oxidative phosphorylation defect type 27
(MONDO_0014728)
Strong
CARS2
(HGNC:25695)
mitochondrial disease
(MONDO_0044970)
Moderate
GPATCH3
(HGNC:25720)
congenital glaucoma
(MONDO_0020366)
Moderate
TRAPPC11
(HGNC:25751)
triple-A syndrome
(MONDO_0009279)
Limited
TRAPPC11
(HGNC:25751)
autosomal recessive limb-girdle muscular dystrophy type R18
(MONDO_0014144)
Definitive
NHEJ1
(HGNC:25737)
Cernunnos-XLF deficiency
(MONDO_0012650)
Strong
TCTN2
(HGNC:25774)
Meckel syndrome
(MONDO_0018921)
Limited
CYBA
(HGNC:2577)
chronic granulomatous disease
(MONDO_0018305)
Definitive
ARMC5
(HGNC:25781)
ACTH-independent macronodular adrenal hyperplasia 2
(MONDO_0014416)
Definitive
REEP1
(HGNC:25786)
hereditary spastic paraplegia 31
(MONDO_0012453)
Definitive
EFL1
(HGNC:25789)
Shwachman-Diamond syndrome
(MONDO_0009833)
Strong
GUF1
(HGNC:25799)
West syndrome
(MONDO_0018097)
Limited
CYC1
(HGNC:2579)
mitochondrial disease
(MONDO_0044970)
Moderate
CPLANE1
(HGNC:25801)
orofaciodigital syndrome type 6
(MONDO_0010176)
Moderate
FAM161A
(HGNC:25808)
retinitis pigmentosa
(MONDO_0019200)
Strong
ADK
(HGNC:257)
adenosine kinase deficiency
(MONDO_0100255)
Definitive
CYLD
(HGNC:2584)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
SRD5A3
(HGNC:25812)
SRD5A3-congenital disorder of glycosylation
(MONDO_0012885)
Strong
GRHL3
(HGNC:25839)
van der Woude syndrome
(MONDO_0019508)
Strong
GINS3
(HGNC:25851)
Meier-Gorlin syndrome
(MONDO_0016817)
Strong
ZNF606
(HGNC:25879)
neuromyelitis optica
(MONDO_0019100)
Limited
CYLD
(HGNC:2584)
familial multiple trichoepithelioma
(MONDO_0011114)
Strong
ORAI1
(HGNC:25896)
tubular aggregate myopathy
(MONDO_0008051)
Strong
ORAI1
(HGNC:25896)
Stormorken syndrome
(MONDO_0008497)
Strong
POMGNT2
(HGNC:25902)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Limited
CEP89
(HGNC:25907)
intellectual disability
(MONDO_0001071)
Limited
MFSD2A
(HGNC:25897)
autosomal recessive primary microcephaly
(MONDO_0016660)
Strong
CYP11A1
(HGNC:2590)
Congenital adrenal insufficiency with 46, XY sex reversal OR 46,XY disorder of sex development-adrenal insufficiency due to CYP11A1 deficiency
(MONDO_0013400)
Strong
CYP11B1
(HGNC:2591)
congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency
(MONDO_0008729)
Strong
CYP11B2
(HGNC:2592)
corticosterone methyloxidase type 2 deficiency
(MONDO_0012524)
Strong
CYP17A1
(HGNC:2593)
congenital adrenal hyperplasia due to 17-alpha-hydroxylase deficiency
(MONDO_0008730)
Strong
TET2
(HGNC:25941)
pulmonary arterial hypertension
(MONDO_0015924)
Strong
KLHL24
(HGNC:25947)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
CYP11B2
(HGNC:2592)
corticosterone methyloxidase type 1 deficiency
(MONDO_0008751)
Definitive
CYP19A1
(HGNC:2594)
aromatase deficiency
(MONDO_0013301)
Strong
CYP19A1
(HGNC:2594)
aromatase excess syndrome
(MONDO_0007690)
Definitive
CYP1B1
(HGNC:2597)
Peters anomaly
(MONDO_0011414)
Strong
CYP1B1
(HGNC:2597)
congenital glaucoma
(MONDO_0020366)
Definitive
NSUN2
(HGNC:25994)
Dubowitz syndrome
(MONDO_0009124)
Moderate
TTC19
(HGNC:26006)
Leigh syndrome
(MONDO_0009723)
Strong
TTC19
(HGNC:26006)
mitochondrial complex III deficiency nuclear type 2
(MONDO_0014063)
Strong
TTC19
(HGNC:26006)
mitochondrial complex III deficiency
(MONDO_0015448)
Strong
CYP21A2
(HGNC:2600)
classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
(MONDO_0008728)
Definitive
TRMT10C
(HGNC:26022)
mitochondrial disease
(MONDO_0044970)
Moderate
CYP24A1
(HGNC:2602)
hypercalcemia, infantile, 1
(MONDO_0020739)
Definitive
PIGV
(HGNC:26031)
hyperphosphatasia with intellectual disability syndrome 1
(MONDO_0009398)
Strong
TMEM127
(HGNC:26038)
renal cell carcinoma
(MONDO_0005086)
Limited
PIGV
(HGNC:26031)
hyperphosphatasia-intellectual disability syndrome
(MONDO_0016596)
Strong
TMEM70
(HGNC:26050)
mitochondrial disease
(MONDO_0044970)
Strong
SLC25A38
(HGNC:26054)
autosomal recessive sideroblastic anemia
(MONDO_0016828)
Definitive
CYP27B1
(HGNC:2606)
vitamin D-dependent rickets, type 1
(MONDO_0009924)
Definitive
CYP2A6
(HGNC:2610)
nicotine dependence
(MONDO_0008575)
Limited
CCDC40
(HGNC:26090)
primary ciliary dyskinesia
(MONDO_0016575)
Definitive
TCTN1
(HGNC:26113)
Meckel syndrome
(MONDO_0018921)
Limited
PALB2
(HGNC:26144)
familial ovarian cancer
(MONDO_0016248)
Strong
PALB2
(HGNC:26144)
Fanconi anemia
(MONDO_0019391)
Definitive
PALB2
(HGNC:26144)
hereditary breast carcinoma
(MONDO_0016419)
Strong
AGBL5
(HGNC:26147)
retinitis pigmentosa
(MONDO_0019200)
Strong
CTC1
(HGNC:26169)
dyskeratosis congenita
(MONDO_0015780)
Strong
COLGALT1
(HGNC:26182)
brain small vessel disease 3
(MONDO_0100105)
Strong
FHOD3
(HGNC:26178)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
STN1
(HGNC:26200)
Coats plus syndrome
(MONDO_0012815)
Moderate
OCEL1
(HGNC:26221)
Aicardi syndrome
(MONDO_0010568)
Disputed
POMK
(HGNC:26267)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Limited
PIEZO2
(HGNC:26270)
arthrogryposis- oculomotor limitation-electroretinal anomalies syndrome
(MONDO_0007158)
Definitive
PIEZO2
(HGNC:26270)
Gordon syndrome
(MONDO_0007252)
Definitive
PIEZO2
(HGNC:26270)
Marden-Walker syndrome
(MONDO_0009564)
Limited
SPEF2
(HGNC:26293)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
NARS2
(HGNC:26274)
combined oxidative phosphorylation defect type 24
(MONDO_0014547)
Strong
NARS2
(HGNC:26274)
mitochondrial disease
(MONDO_0044970)
Strong
SCLT1
(HGNC:26406)
Bardet-Biedl syndrome
(MONDO_0015229)
Moderate
HEPACAM
(HGNC:26361)
megalencephalic leukoencephalopathy with subcortical cysts 2A
(MONDO_0013490)
Strong
HEPACAM
(HGNC:26361)
megalencephalic leukoencephalopathy with subcortical cysts
(MONDO_0011391)
Definitive
UROC1
(HGNC:26444)
urocanic aciduria
(MONDO_0010167)
Disputed
ZMAT2
(HGNC:26433)
congenital radioulnar synostosis
(MONDO_0017985)
Limited
NARS2
(HGNC:26274)
Leigh syndrome
(MONDO_0009723)
Moderate
AGBL1
(HGNC:26504)
Fuchs' endothelial dystrophy
(MONDO_0005321)
Disputed
LOXHD1
(HGNC:26521)
Fuchs' endothelial dystrophy
(MONDO_0005321)
Disputed
HGSNAT
(HGNC:26527)
mucopolysaccharidosis type 3
(MONDO_0018937)
Definitive
HGSNAT
(HGNC:26527)
retinitis pigmentosa
(MONDO_0019200)
Strong
CYP7B1
(HGNC:2652)
congenital bile acid synthesis defect 3
(MONDO_0013439)
Limited
DZIP1L
(HGNC:26551)
autosomal recessive polycystic kidney disease
(MONDO_0009889)
Moderate
CFAP53
(HGNC:26530)
situs inversus
(MONDO_0010029)
Moderate
ODAD1
(HGNC:26560)
primary ciliary dyskinesia 20
(MONDO_0014030)
Moderate
UNC80
(HGNC:26582)
hypotonia, infantile, with psychomotor retardation and characteristic facies 2
(MONDO_0014777)
Strong
DOK7
(HGNC:26594)
congenital myasthenic syndrome 10
(MONDO_0009690)
Definitive
DOK7
(HGNC:26594)
fetal akinesia deformation sequence 1
(MONDO_0100101)
Moderate
WDR81
(HGNC:26600)
cerebellar ataxia, intellectual disability, and dysequilibrium syndrome 2
(MONDO_0012430)
Strong
POC5
(HGNC:26658)
retinitis pigmentosa
(MONDO_0019200)
Limited
CYP7B1
(HGNC:2652)
hereditary spastic paraplegia 5A
(MONDO_0010047)
Definitive
LOXHD1
(HGNC:26521)
autosomal recessive nonsyndromic hearing loss 77
(MONDO_0013119)
Definitive
RNF168
(HGNC:26661)
RIDDLE syndrome
(MONDO_0012764)
Moderate
CFAP43
(HGNC:26684)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
CFAP43
(HGNC:26684)
normal pressure hydrocephalus
(MONDO_0009366)
Moderate
BBS12
(HGNC:26648)
Bardet-Biedl syndrome
(MONDO_0015229)
Definitive
CEP120
(HGNC:26690)
ciliopathy
(MONDO_0005308)
Moderate
DAB1
(HGNC:2661)
spinocerebellar ataxia type 37
(MONDO_0014410)
Strong
CEP120
(HGNC:26690)
Jeune syndrome
(MONDO_0018770)
Strong
CEP120
(HGNC:26690)
Joubert syndrome
(MONDO_0018772)
Moderate
CFAP47
(HGNC:26708)
polycystic kidney disease
(MONDO_0020642)
Limited
CD55
(HGNC:2665)
protein-losing enteropathy
(MONDO_0009174)
Strong
MTRFR
(HGNC:26784)
Leigh syndrome
(MONDO_0009723)
Moderate
MTRFR
(HGNC:26784)
combined oxidative phosphorylation defect type 7
(MONDO_0013306)
Moderate
DARS1
(HGNC:2678)
hypomyelination with brain stem and spinal cord involvement and leg spasticity
(MONDO_0014115)
Limited
WDR72
(HGNC:26790)
renal tubular acidosis
(MONDO_0001909)
Limited
WDR72
(HGNC:26790)
amelogenesis imperfecta
(MONDO_0019507)
Definitive
RILPL1
(HGNC:26814)
oculopharyngodistal myopathy 4
(MONDO_0030712)
Limited
CYP4F22
(HGNC:26820)
lamellar ichthyosis
(MONDO_0017778)
Moderate
CCDC141
(HGNC:26821)
hypogonadotropic hypogonadism
(MONDO_0018555)
Moderate
CCDC141
(HGNC:26821)
Kallmann syndrome
(MONDO_0018800)
Limited
TMTC3
(HGNC:26899)
periventricular nodular heterotopia
(MONDO_0020341)
Strong
DBH
(HGNC:2689)
orthostatic hypotension 1
(MONDO_0009123)
Strong
FOXRED1
(HGNC:26927)
Leigh syndrome
(MONDO_0009723)
Strong
FOXRED1
(HGNC:26927)
mitochondrial disease
(MONDO_0044970)
Strong
CDIN1
(HGNC:26929)
congenital dyserythropoietic anemia type 1
(MONDO_0020337)
Moderate
HIKESHI
(HGNC:26938)
hypomyelinating leukodystrophy 13
(MONDO_0014813)
Limited
BLTP1
(HGNC:26953)
Alkuraya-Kucinskas syndrome
(MONDO_0060631)
Limited
PDZD8
(HGNC:26974)
intellectual developmental disorder with autism and dysmorphic facies
(MONDO_0859281)
Strong
DCC
(HGNC:2701)
esophageal cancer
(MONDO_0007576)
Limited
METTL23
(HGNC:26988)
intellectual disability, autosomal recessive 44
(MONDO_0014409)
Strong
DCC
(HGNC:2701)
colorectal cancer
(MONDO_0005575)
Strong
DCC
(HGNC:2701)
Kallmann syndrome
(MONDO_0018800)
Moderate
DCC
(HGNC:2701)
familial congenital mirror movements
(MONDO_0016558)
Strong
C5orf47
(HGNC:27026)
neuromyelitis optica
(MONDO_0019100)
Limited
DNAJC21
(HGNC:27030)
Shwachman-Diamond syndrome
(MONDO_0009833)
Moderate
DNAJC21
(HGNC:27030)
bone marrow failure syndrome 3
(MONDO_0014887)
Moderate
DCN
(HGNC:2705)
congenital stromal corneal dystrophy
(MONDO_0012401)
Moderate
CARMIL2
(HGNC:27089)
severe combined immunodeficiency due to CARMIL2 deficiency
(MONDO_0029134)
Limited
DCT
(HGNC:2709)
oculocutaneous albinism type 8
(MONDO_0030899)
Strong
DCTN1
(HGNC:2711)
amyotrophic lateral sclerosis
(MONDO_0004976)
Moderate
DCTN1
(HGNC:2711)
Perry syndrome
(MONDO_0008201)
Definitive
DCTN1
(HGNC:2711)
neuronopathy, distal hereditary motor, type 7B
(MONDO_0011879)
Moderate
DDB2
(HGNC:2718)
xeroderma pigmentosum group E
(MONDO_0010213)
Moderate
DDB2
(HGNC:2718)
xeroderma pigmentosum
(MONDO_0019600)
Definitive
ACSF3
(HGNC:27288)
combined malonic and methylmalonic acidemia
(MONDO_0013661)
Definitive
DDOST
(HGNC:2728)
DDOST-congenital disorder of glycosylation
(MONDO_0013789)
Moderate
IBA57
(HGNC:27302)
multiple mitochondrial dysfunctions syndrome 3
(MONDO_0014132)
Strong
IBA57
(HGNC:27302)
mitochondrial disease
(MONDO_0044970)
Strong
FLCN
(HGNC:27310)
colorectal cancer
(MONDO_0005575)
Limited
FLCN
(HGNC:27310)
familial spontaneous pneumothorax
(MONDO_0008259)
Strong
DDR2
(HGNC:2731)
warburg-cinotti syndrome
(MONDO_0032579)
Strong
ANO5
(HGNC:27337)
gnathodiaphyseal dysplasia
(MONDO_0008151)
Strong
ANO5
(HGNC:27337)
autosomal recessive limb-girdle muscular dystrophy type 2L
(MONDO_0012652)
Strong
ANO5
(HGNC:27337)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Strong
TECRL
(HGNC:27365)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Moderate
RBM20
(HGNC:27424)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
DDX3X
(HGNC:2745)
Toriello-Carey syndrome
(MONDO_0009021)
Limited
TSEN54
(HGNC:27561)
pontocerebellar hypoplasia type 2A
(MONDO_0010190)
Strong
TSEN54
(HGNC:27561)
pontocerebellar hypoplasia type 2
(MONDO_0016759)
Definitive
EMC10
(HGNC:27609)
neurodevelopmental disorder with dysmorphic facies and variable seizures
(MONDO_0031011)
Strong
DES
(HGNC:2770)
atrioventricular block
(MONDO_0000465)
Limited
DES
(HGNC:2770)
dilated cardiomyopathy
(MONDO_0005021)
Strong
DES
(HGNC:2770)
myofibrillar myopathy 1
(MONDO_0011076)
Strong
DES
(HGNC:2770)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Moderate
STING1
(HGNC:27962)
familial chilblain lupus
(MONDO_0018827)
Moderate
GRHL2
(HGNC:2799)
posterior polymorphous corneal dystrophy
(MONDO_0020364)
Strong
NIPAL4
(HGNC:28018)
lamellar ichthyosis
(MONDO_0017778)
Strong
NIPAL4
(HGNC:28018)
congenital non-bullous ichthyosiform erythroderma
(MONDO_0019306)
Moderate
WDPCP
(HGNC:28027)
Bardet-Biedl syndrome
(MONDO_0015229)
Limited
LYRM7
(HGNC:28072)
mitochondrial disease
(MONDO_0044970)
Definitive
NDUFAF2
(HGNC:28086)
Leigh syndrome
(MONDO_0009723)
Strong
GSDME
(HGNC:2810)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Strong
NDUFAF2
(HGNC:28086)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
TMEM107
(HGNC:28128)
ciliopathy
(MONDO_0005308)
Limited
CCDC115
(HGNC:28178)
CCDC115-CDG
(MONDO_0014789)
Strong
CEP19
(HGNC:28209)
Bardet-Biedl syndrome
(MONDO_0015229)
Limited
CFAP300
(HGNC:28188)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
HPDL
(HGNC:28242)
neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities
(MONDO_0033613)
Moderate
PHYKPL
(HGNC:28249)
phosphohydroxylysinuria
(MONDO_0014008)
Limited
TBCK
(HGNC:28261)
hypotonia, infantile, with psychomotor retardation and characteristic facies 3
(MONDO_0014823)
Definitive
DYNC2I2
(HGNC:28296)
Jeune syndrome
(MONDO_0018770)
Strong
ODAD3
(HGNC:28303)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
TET3
(HGNC:28313)
Beck-Fahrner syndrome
(MONDO_0032922)
Strong
C9orf72
(HGNC:28337)
progressive myoclonus epilepsy
(MONDO_0020074)
Limited
D2HGDH
(HGNC:28358)
D-2-hydroxyglutaric aciduria
(MONDO_0010924)
Definitive
SGMS2
(HGNC:28395)
calvarial doughnut lesions-bone fragility syndrome
(MONDO_0007470)
Strong
TMEM67
(HGNC:28396)
ciliopathy
(MONDO_0005308)
Strong
TMEM67
(HGNC:28396)
Joubert syndrome
(MONDO_0018772)
Definitive
TMEM67
(HGNC:28396)
Joubert syndrome 6
(MONDO_0012539)
Strong
TMEM67
(HGNC:28396)
Meckel syndrome
(MONDO_0018921)
Definitive
MFSD8
(HGNC:28486)
neuronal ceroid lipofuscinosis 7
(MONDO_0012588)
Limited
EOGT
(HGNC:28526)
Adams-Oliver syndrome
(MONDO_0007034)
Strong
KLHDC8B
(HGNC:28557)
classic Hodgkin lymphoma
(MONDO_0009348)
Limited
DGUOK
(HGNC:2858)
mitochondrial DNA depletion syndrome 3 (hepatocerebral type)
(MONDO_0009636)
Strong
B3GALNT2
(HGNC:28596)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Strong
SNX31
(HGNC:28605)
schizophrenia
(MONDO_0005090)
Limited
B3GALNT2
(HGNC:28596)
muscle-eye-brain disease
(MONDO_0018939)
Strong
RICTOR
(HGNC:28611)
Tourette syndrome
(MONDO_0007661)
Limited
DHFR
(HGNC:2861)
constitutional megaloblastic anemia with severe neurologic disease
(MONDO_0013456)
Limited
NDUFAF6
(HGNC:28625)
Leigh syndrome
(MONDO_0009723)
Strong
DHCR7
(HGNC:2860)
Smith-Lemli-Opitz syndrome
(MONDO_0010035)
Definitive
B9D2
(HGNC:28636)
Meckel syndrome
(MONDO_0018921)
Moderate
DIS3L2
(HGNC:28648)
Perlman syndrome
(MONDO_0009965)
Definitive
DHH
(HGNC:2865)
46,XY complete gonadal dysgenesis
(MONDO_0010765)
Strong
DHODH
(HGNC:2867)
postaxial acrofacial dysostosis
(MONDO_0009903)
Strong
COQ5
(HGNC:28722)
neurodevelopmental disorder
(MONDO_0700092)
Strong
AFG2B
(HGNC:28762)
neurodevelopmental disorder with hearing loss and spasticity
(MONDO_0859206)
Limited
CYB5R3
(HGNC:2873)
hereditary methemoglobinemia
(MONDO_0018963)
Strong
CYB5R3
(HGNC:2873)
methemoglobinemia due to deficiency of methemoglobin reductase
(MONDO_0009606)
Definitive
DRAM2
(HGNC:28769)
cone-rod dystrophy 21
(MONDO_0014669)
Strong
DIAPH1
(HGNC:2876)
autosomal dominant nonsyndromic hearing loss 1
(MONDO_0007424)
Strong
P4HTM
(HGNC:28858)
hypotonia, hypoventilation, impaired intellectual development, dysautonomia, epilepsy, and eye abnormalities
(MONDO_0032780)
Strong
MAGT1
(HGNC:28880)
X-linked intellectual disability
(MONDO_0100284)
Disputed
DRAM2
(HGNC:28769)
cone-rod dystrophy
(MONDO_0015993)
Strong
DIAPH1
(HGNC:2876)
progressive microcephaly-seizures-cortical blindness-developmental delay syndrome
(MONDO_0014714)
Definitive
MAGT1
(HGNC:28880)
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia
(MONDO_0010455)
Strong
SAMD11
(HGNC:28706)
retinitis pigmentosa
(MONDO_0019200)
Moderate
CCDC22
(HGNC:28909)
epilepsy
(MONDO_0005027)
Limited
CCDC120
(HGNC:28910)
osteopetrosis
(MONDO_0017198)
Limited
WDR45
(HGNC:28912)
West syndrome
(MONDO_0018097)
Moderate
CCDC22
(HGNC:28909)
Ritscher-Schinzel syndrome
(MONDO_0019078)
Strong
JAZF1
(HGNC:28917)
systemic lupus erythematosus
(MONDO_0007915)
Limited
IQCB1
(HGNC:28949)
Senior-Loken syndrome
(MONDO_0017842)
Definitive
KRT71
(HGNC:28927)
isolated familial wooly hair disorder
(MONDO_0008686)
Moderate
IQCB1
(HGNC:28949)
Leber congenital amaurosis
(MONDO_0018998)
Definitive
NUP93
(HGNC:28958)
familial idiopathic steroid-resistant nephrotic syndrome
(MONDO_0019006)
Strong
TMEM94
(HGNC:28983)
intellectual developmental disorder with cardiac defects and dysmorphic facies
(MONDO_0032672)
Limited
DLAT
(HGNC:2896)
Leigh syndrome
(MONDO_0009723)
Limited
WASHC5
(HGNC:28984)
hereditary spastic paraplegia 8
(MONDO_0011339)
Moderate
WASHC5
(HGNC:28984)
Ritscher-Schinzel syndrome
(MONDO_0019078)
Strong
EMC1
(HGNC:28957)
cerebellar atrophy, visual impairment, and psychomotor retardation;
(MONDO_0014811)
Strong
PIEZO1
(HGNC:28993)
lymphatic malformation 6
(MONDO_0014797)
Strong
RUBCN
(HGNC:28991)
autosomal recessive spinocerebellar ataxia 15
(MONDO_0014311)
Limited
FRMPD4
(HGNC:29007)
intellectual disability, X-linked 104
(MONDO_0010509)
Strong
DLG1
(HGNC:2900)
Brugada syndrome
(MONDO_0015263)
Moderate
GRK2
(HGNC:289)
Jeune syndrome
(MONDO_0018770)
Limited
KDM6B
(HGNC:29012)
neurodevelopmental disorder
(MONDO_0700092)
Strong
KDM6B
(HGNC:29012)
neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities
(MONDO_0032790)
Definitive
CEP290
(HGNC:29021)
Bardet-Biedl syndrome
(MONDO_0015229)
Limited
CEP290
(HGNC:29021)
Joubert syndrome with oculorenal defect
(MONDO_0009480)
Strong
CEP290
(HGNC:29021)
Senior-Loken syndrome
(MONDO_0017842)
Strong
CEP290
(HGNC:29021)
Leber congenital amaurosis 10
(MONDO_0012723)
Strong
CEP290
(HGNC:29021)
Meckel syndrome
(MONDO_0018921)
Definitive
CEP290
(HGNC:29021)
Leber congenital amaurosis
(MONDO_0018998)
Definitive
SZT2
(HGNC:29040)
developmental and epileptic encephalopathy, 18
(MONDO_0014201)
Strong
SZT2
(HGNC:29040)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
DSTYK
(HGNC:29043)
hereditary spastic paraplegia 23
(MONDO_0010046)
Strong
DSTYK
(HGNC:29043)
renal agenesis, unilateral
(MONDO_0019636)
Limited
KATNIP
(HGNC:29068)
Joubert syndrome
(MONDO_0018772)
Strong
IFT140
(HGNC:29077)
Jeune syndrome
(MONDO_0018770)
Strong
IFT140
(HGNC:29077)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Definitive
IFT140
(HGNC:29077)
Leber congenital amaurosis
(MONDO_0018998)
Moderate
IFT140
(HGNC:29077)
retinitis pigmentosa
(MONDO_0019200)
Strong
CEP135
(HGNC:29086)
autosomal recessive primary microcephaly
(MONDO_0016660)
Moderate
SMCHD1
(HGNC:29090)
facioscapulohumeral muscular dystrophy
(MONDO_0001347)
Definitive
SMCHD1
(HGNC:29090)
arhinia, choanal atresia, and microphthalmia
(MONDO_0011323)
Definitive
OBSL1
(HGNC:29092)
3-M syndrome
(MONDO_0007477)
Strong
OBSL1
(HGNC:29092)
3M syndrome 2
(MONDO_0013039)
Definitive
ANKLE2
(HGNC:29101)
autosomal recessive primary microcephaly
(MONDO_0016660)
Strong
TELO2
(HGNC:29099)
TELO2-related intellectual disability-neurodevelopmental disorder
(MONDO_0014848)
Strong
PLEKHG5
(HGNC:29105)
neuromuscular disease
(MONDO_0019056)
Strong
DDHD2
(HGNC:29106)
hereditary spastic paraplegia 54
(MONDO_0014018)
Definitive
DLL4
(HGNC:2910)
aplasia cutis congenita
(MONDO_0007145)
Limited
PLEKHM2
(HGNC:29131)
dilated cardiomyopathy
(MONDO_0005021)
Limited
MAU2
(HGNC:29140)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
FASTKD2
(HGNC:29160)
combined oxidative phosphorylation deficiency 44
(MONDO_0030020)
Limited
RPGRIP1L
(HGNC:29168)
Meckel syndrome
(MONDO_0018921)
Strong
RPGRIP1L
(HGNC:29168)
Joubert syndrome 7
(MONDO_0012694)
Moderate
WASHC4
(HGNC:29174)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Strong
CEP164
(HGNC:29182)
ciliopathy
(MONDO_0005308)
Limited
CEP164
(HGNC:29182)
Senior-Loken syndrome
(MONDO_0017842)
Strong
FAN1
(HGNC:29170)
hereditary nonpolyposis colon cancer
(MONDO_0018630)
Strong
ANKRD26
(HGNC:29186)
thrombocytopenia 2
(MONDO_0008555)
Definitive
ANKRD26
(HGNC:29186)
acute myeloid leukemia
(MONDO_0018874)
Moderate
TBC1D24
(HGNC:29203)
autosomal recessive nonsyndromic hearing loss 86
(MONDO_0013826)
Moderate
TNRC6B
(HGNC:29190)
global developmental delay with speech and behavioral abnormalities
(MONDO_0030995)
Strong
TBC1D24
(HGNC:29203)
malignant migrating partial seizures of infancy
(MONDO_0017385)
Limited
TBC1D24
(HGNC:29203)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Moderate
INTU
(HGNC:29239)
orofaciodigital syndrome 17
(MONDO_0033375)
Limited
PRR12
(HGNC:29217)
neuroocular syndrome
(MONDO_0859193)
Limited
WDR35
(HGNC:29250)
short-rib thoracic dysplasia 7 with or without polydactyly
(MONDO_0013569)
Limited
CC2D2A
(HGNC:29253)
Joubert syndrome 9
(MONDO_0012849)
Strong
USP53
(HGNC:29255)
cholestasis
(MONDO_0001751)
Strong
CC2D2A
(HGNC:29253)
Meckel syndrome
(MONDO_0018921)
Definitive
IFT80
(HGNC:29262)
Beemer-Langer syndrome
(MONDO_0010024)
Moderate
IFT80
(HGNC:29262)
Jeune syndrome
(MONDO_0018770)
Limited
DMD
(HGNC:2928)
Becker muscular dystrophy
(MONDO_0010311)
Definitive
DMD
(HGNC:2928)
dilated cardiomyopathy 3B
(MONDO_0010542)
Definitive
DMD
(HGNC:2928)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Limited
DMD
(HGNC:2928)
Duchenne muscular dystrophy
(MONDO_0010679)
Definitive
DMD
(HGNC:2928)
progressive muscular dystrophy
(MONDO_0016106)
Limited
CEP152
(HGNC:29298)
autosomal recessive primary microcephaly
(MONDO_0016660)
Limited
CEP152
(HGNC:29298)
Seckel syndrome
(MONDO_0019342)
Strong
SLC7A14
(HGNC:29326)
retinitis pigmentosa
(MONDO_0019200)
Limited
UVSSA
(HGNC:29304)
UV-sensitive syndrome
(MONDO_0015797)
Definitive
DMP1
(HGNC:2932)
autosomal recessive hypophosphatemic rickets
(MONDO_0017324)
Moderate
DMRT1
(HGNC:2934)
46,XY disorder of sex development
(MONDO_0020040)
Limited
ASXL3
(HGNC:29357)
syndromic intellectual disability
(MONDO_0000508)
Definitive
DMXL2
(HGNC:2938)
developmental and epileptic encephalopathy, 81
(MONDO_0032858)
Limited
CFAP74
(HGNC:29368)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
DMRT2
(HGNC:2935)
spondylocostal dysostosis
(MONDO_0000359)
Limited
DNAH1
(HGNC:2940)
primary ciliary dyskinesia
(MONDO_0016575)
Moderate
ANKRD24
(HGNC:29424)
sensorineural hearing loss disorder
(MONDO_0020678)
Limited
CLTRN
(HGNC:29437)
Hartnup disease
(MONDO_0009324)
Moderate
DNAH3
(HGNC:2949)
male infertility
(MONDO_0005372)
Strong
NEXMIF
(HGNC:29433)
myoclonic-astatic epilepsy
(MONDO_0016025)
Limited
DNAH14
(HGNC:2945)
neurodevelopmental disorder
(MONDO_0700092)
Limited
TBL1XR1
(HGNC:29529)
Pierpont syndrome
(MONDO_0011213)
Strong
GLDN
(HGNC:29514)
lethal congenital contracture syndrome 11
(MONDO_0014965)
Strong
DNAH9
(HGNC:2953)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
DNAH9
(HGNC:2953)
situs inversus
(MONDO_0010029)
Strong
DNAH8
(HGNC:2952)
primary ciliary dyskinesia
(MONDO_0016575)
Disputed
DNAI1
(HGNC:2954)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
LIPT1
(HGNC:29569)
Leigh syndrome
(MONDO_0009723)
Strong
NEXN
(HGNC:29557)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
DNASE1
(HGNC:2956)
systemic lupus erythematosus
(MONDO_0007915)
Limited
DNASE1L3
(HGNC:2959)
hypocomplementemic urticarial vasculitis
(MONDO_0018227)
Strong
SH2B3
(HGNC:29605)
acute lymphoblastic leukemia
(MONDO_0004967)
Limited
MLPH
(HGNC:29643)
Griscelli syndrome type 3
(MONDO_0012220)
Strong
DYNC1H1
(HGNC:2961)
autosomal dominant childhood-onset proximal spinal muscular atrophy without contractures
(MONDO_0008026)
Strong
ROGDI
(HGNC:29478)
amelocerebrohypohidrotic syndrome
(MONDO_0009185)
Strong
DYNC2H1
(HGNC:2962)
Jeune syndrome
(MONDO_0018770)
Strong
PJVK
(HGNC:29502)
autosomal recessive nonsyndromic hearing loss 59
(MONDO_0012445)
Moderate
KIDINS220
(HGNC:29508)
spastic paraplegia, intellectual disability, nystagmus, and obesity
(MONDO_0015007)
Strong
IFT43
(HGNC:29669)
cranioectodermal dysplasia
(MONDO_0009032)
Limited
GNPTAB
(HGNC:29670)
mucolipidosis type III, alpha/beta
(MONDO_0018931)
Definitive
GNPTAB
(HGNC:29670)
mucolipidosis
(MONDO_0019248)
Strong
MSTO1
(HGNC:29678)
mitochondrial disease
(MONDO_0044970)
Strong
IARS2
(HGNC:29685)
Leigh syndrome
(MONDO_0009723)
Strong
DNM1
(HGNC:2972)
Lennox-Gastaut syndrome
(MONDO_0016532)
Strong
DNM1
(HGNC:2972)
developmental and epileptic encephalopathy
(MONDO_0100062)
Definitive
IARS2
(HGNC:29685)
cataract-growth hormone deficiency-sensory neuropathy-sensorineural hearing loss-skeletal dysplasia syndrome
(MONDO_0014455)
Strong
DNM1L
(HGNC:2973)
encephalopathy due to mitochondrial and peroxisomal fission defect
(MONDO_0054865)
Moderate
DNM2
(HGNC:2974)
fetal akinesia-cerebral and retinal hemorrhage syndrome
(MONDO_0014149)
Limited
DNM2
(HGNC:2974)
Charcot-Marie-Tooth disease dominant intermediate B
(MONDO_0011674)
Limited
DNMT1
(HGNC:2976)
hereditary sensory neuropathy-deafness-dementia syndrome
(MONDO_0013584)
Strong
DNM1L
(HGNC:2973)
autosomal dominant optic atrophy, classic form
(MONDO_0008134)
Strong
DNMT3A
(HGNC:2978)
Heyn-Sproul-Jackson syndrome
(MONDO_0032882)
Limited
DNM2
(HGNC:2974)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
DNMT3A
(HGNC:2978)
Tatton-Brown-Rahman overgrowth syndrome
(MONDO_0014382)
Definitive
DNMT1
(HGNC:2976)
autosomal dominant cerebellar ataxia, deafness and narcolepsy
(MONDO_0011397)
Strong
DNMT3B
(HGNC:2979)
immunodeficiency-centromeric instability-facial anomalies syndrome
(MONDO_0000133)
Definitive
DCPS
(HGNC:29812)
Al-Raqad syndrome
(MONDO_0014648)
Strong
DNMT3B
(HGNC:2979)
facioscapulohumeral muscular dystrophy
(MONDO_0001347)
Limited
NADSYN1
(HGNC:29832)
congenital vertebral-cardiac-renal anomalies syndrome
(MONDO_0020831)
Strong
MYLK3
(HGNC:29826)
dilated cardiomyopathy
(MONDO_0005021)
Strong
NUP107
(HGNC:29914)
46 XX gonadal dysgenesis
(MONDO_0009299)
Moderate
NSMF
(HGNC:29843)
hypogonadotropic hypogonadism
(MONDO_0018555)
Limited
HECW2
(HGNC:29853)
neurodevelopmental disorder with hypotonia, seizures, and absent language
(MONDO_0014995)
Limited
NUP107
(HGNC:29914)
familial idiopathic steroid-resistant nephrotic syndrome
(MONDO_0019006)
Limited
MDM1
(HGNC:29917)
schizophrenia
(MONDO_0005090)
Limited
NUP107
(HGNC:29914)
Galloway-Mowat syndrome
(MONDO_0009627)
Strong
NDUFAF3
(HGNC:29918)
mitochondrial disease
(MONDO_0044970)
Strong
COASY
(HGNC:29932)
neurodegeneration with brain iron accumulation 6
(MONDO_0014290)
Moderate
SPATA16
(HGNC:29935)
spermatogenic failure 6
(MONDO_0007060)
Limited
NDUFAF3
(HGNC:29918)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
DPAGT1
(HGNC:2995)
DPAGT1-congenital disorder of glycosylation
(MONDO_0011964)
Definitive
COASY
(HGNC:29932)
pontocerebellar hypoplasia, type 12
(MONDO_0032643)
Strong
ABCA1
(HGNC:29)
Tangier disease
(MONDO_0008783)
Definitive
PACS1
(HGNC:30032)
Schuurs-Hoeijmakers syndrome
(MONDO_0014006)
Definitive
DPM1
(HGNC:3005)
congenital disorder of glycosylation type 1E
(MONDO_0012123)
Strong
PIK3R5
(HGNC:30035)
spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2
(MONDO_0018996)
Limited
KIAA0319L
(HGNC:30071)
systemic lupus erythematosus
(MONDO_0007915)
Limited
POLR3A
(HGNC:30074)
odontoleukodystrophy
(MONDO_0019177)
Strong
POLR3A
(HGNC:30074)
leukoencephalopathy-ataxia-hypodontia-hypomyelination syndrome
(MONDO_0011897)
Moderate
REEP6
(HGNC:30078)
retinitis pigmentosa 77
(MONDO_0015013)
Strong
PSENEN
(HGNC:30100)
Dowling-Degos disease
(MONDO_0008371)
Strong
DPP6
(HGNC:3010)
paroxysmal familial ventricular fibrillation
(MONDO_0100234)
Definitive
POP1
(HGNC:30129)
anauxetic dysplasia
(MONDO_0011773)
Strong
DPYD
(HGNC:3012)
dihydropyrimidine dehydrogenase deficiency
(MONDO_0010130)
Definitive
DPYS
(HGNC:3013)
dihydropyrimidinuria
(MONDO_0009111)
Strong
DPYSL2
(HGNC:3014)
schizophrenia
(MONDO_0005090)
Limited
STRADA
(HGNC:30172)
polyhydramnios, megalencephaly, and symptomatic epilepsy
(MONDO_0012611)
Strong
CRBN
(HGNC:30185)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Moderate
ATP13A2
(HGNC:30213)
Kufor-Rakeb syndrome
(MONDO_0011706)
Definitive
RFT1
(HGNC:30220)
RFT1-congenital disorder of glycosylation
(MONDO_0012783)
Definitive
SLC52A2
(HGNC:30224)
Brown-Vialetto-van Laere syndrome 2
(MONDO_0013867)
Strong
SLC52A1
(HGNC:30225)
ariboflavinosis
(MONDO_0004573)
Limited
PREPL
(HGNC:30228)
hypotonia-cystinuria syndrome
(MONDO_0011669)
Definitive
PREPL
(HGNC:30228)
myasthenic syndrome, congenital, 22
(MONDO_0044299)
Strong
CC2D1A
(HGNC:30237)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Strong
WLS
(HGNC:30238)
Zaki syndrome
(MONDO_0859209)
Strong
TUSC3
(HGNC:30242)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Strong
PNPO
(HGNC:30260)
pyridoxal phosphate-responsive seizures
(MONDO_0012407)
Strong
PYCR2
(HGNC:30262)
hypomyelinating leukodystrophy 10
(MONDO_0014632)
Strong
DRD5
(HGNC:3026)
attention deficit-hyperactivity disorder
(MONDO_0007743)
Limited
RGS9BP
(HGNC:30304)
bradyopsia
(MONDO_0012033)
Moderate
ARHGEF28
(HGNC:30322)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
RIC3
(HGNC:30338)
Parkinson disease
(MONDO_0005180)
Disputed
ATN1
(HGNC:3033)
congenital hypotonia, epilepsy, developmental delay, and digital anomalies
(MONDO_0032781)
Moderate
POLR3B
(HGNC:30348)
hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism
(MONDO_0013722)
Strong
KLHL40
(HGNC:30372)
nemaline myopathy 8
(MONDO_0014138)
Strong
SCAMP5
(HGNC:30386)
epilepsy
(MONDO_0005027)
Strong
IFT172
(HGNC:30391)
short-rib thoracic dysplasia 9 with or without polydactyly
(MONDO_0009964)
Limited
IFT172
(HGNC:30391)
Jeune syndrome
(MONDO_0018770)
Limited
DSCAM
(HGNC:3039)
autism spectrum disorder
(MONDO_0005258)
Moderate
AEBP1
(HGNC:303)
Ehlers-Danlos syndrome, classic-like, 2
(MONDO_0054813)
Strong
SHROOM3
(HGNC:30422)
neural tube defect
(MONDO_0018075)
Moderate
PIGP
(HGNC:3046)
developmental and epileptic encephalopathy, 55
(MONDO_0033364)
Limited
KIF7
(HGNC:30497)
acrocallosal syndrome
(MONDO_0008708)
Strong
DSG2
(HGNC:3049)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
PRRT2
(HGNC:30500)
infantile convulsions and choreoathetosis
(MONDO_0011178)
Strong
PRRT2
(HGNC:30500)
benign familial infantile epilepsy
(MONDO_0017615)
Definitive
PRRT2
(HGNC:30500)
neurodevelopmental disorder
(MONDO_0700092)
Limited
DSP
(HGNC:3052)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
YIF1B
(HGNC:30511)
Kaya-Barakat-Masson syndrome
(MONDO_0030878)
Strong
DSP
(HGNC:3052)
lethal acantholytic epidermolysis bullosa
(MONDO_0012323)
Moderate
DSP
(HGNC:3052)
cardiomyopathy, dilated, with wooly hair, keratoderma, and tooth agenesis
(MONDO_0014355)
Limited
DSP
(HGNC:3052)
severe dermatitis-multiple allergies-metabolic wasting syndrome
(MONDO_0014218)
Limited
DSP
(HGNC:3052)
arrhythmogenic cardiomyopathy with wooly hair and keratoderma
(MONDO_0011581)
Definitive
DSPP
(HGNC:3054)
dentin dysplasia type II
(MONDO_0007437)
Moderate
DSP
(HGNC:3052)
striate palmoplantar keratoderma
(MONDO_0018865)
Limited
DSPP
(HGNC:3054)
dentinogenesis imperfecta type 2
(MONDO_0007441)
Limited
DSPP
(HGNC:3054)
dentinogenesis imperfecta type 3
(MONDO_0007442)
Strong
MARCHF6
(HGNC:30550)
benign adult familial myoclonic epilepsy
(MONDO_0019448)
Refuted
DNAAF1
(HGNC:30539)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
DTNA
(HGNC:3057)
Meniere disease
(MONDO_0007972)
Limited
TXNL4A
(HGNC:30551)
choanal atresia-hearing loss-cardiac defects-craniofacial dysmorphism syndrome
(MONDO_0012064)
Strong
PARS2
(HGNC:30563)
mitochondrial disease
(MONDO_0044970)
Limited
SEPSECS
(HGNC:30605)
pontocerebellar hypoplasia type 2
(MONDO_0016759)
Strong
UBA2
(HGNC:30661)
ACCES syndrome
(MONDO_0859262)
Strong
DTYMK
(HGNC:3061)
mitochondrial DNA depletion syndrome
(MONDO_0018158)
Limited
TSHZ3
(HGNC:30700)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Strong
DNAJB13
(HGNC:30718)
primary ciliary dyskinesia
(MONDO_0016575)
Limited
PPP1R21
(HGNC:30595)
neurodevelopmental disorder with hypotonia, facial dysmorphism, and brain abnormalities
(MONDO_0859165)
Strong
DUSP6
(HGNC:3072)
hypogonadotropic hypogonadism
(MONDO_0018555)
Limited
DUSP6
(HGNC:3072)
Kallmann syndrome
(MONDO_0018800)
Limited
TMEM165
(HGNC:30760)
TMEM165-congenital disorder of glycosylation
(MONDO_0013870)
Moderate
GATAD2B
(HGNC:30778)
severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome
(MONDO_0014034)
Strong
CEP57
(HGNC:30794)
mosaic variegated aneuploidy syndrome
(MONDO_0000141)
Strong
TM9SF4
(HGNC:30797)
autism spectrum disorder
(MONDO_0005258)
Limited
CEP57
(HGNC:30794)
mosaic variegated aneuploidy syndrome 2
(MONDO_0013582)
Strong
TUBB2B
(HGNC:30829)
congenital fibrosis of extraocular muscles
(MONDO_0007614)
Limited
TRAPPC9
(HGNC:30832)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Strong
POC1B
(HGNC:30836)
cone-rod dystrophy
(MONDO_0015993)
Strong
SNRNP200
(HGNC:30859)
retinitis pigmentosa
(MONDO_0019200)
Strong
ALG13
(HGNC:30881)
developmental and epileptic encephalopathy, 36
(MONDO_0010472)
Definitive
ALG13
(HGNC:30881)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Limited
PDGFD
(HGNC:30620)
pulmonary arterial hypertension
(MONDO_0015924)
Moderate
ALG13
(HGNC:30881)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
TMEM126B
(HGNC:30883)
mitochondrial disease
(MONDO_0044970)
Strong
TMEM126B
(HGNC:30883)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
ATP5MK
(HGNC:30889)
Leigh syndrome
(MONDO_0009723)
Strong
SLC6A20
(HGNC:30927)
hyperglycinuria
(MONDO_0007677)
Moderate
DYRK1B
(HGNC:3092)
abdominal obesity-metabolic syndrome 3
(MONDO_0014352)
Strong
DYSF
(HGNC:3097)
autosomal recessive limb-girdle muscular dystrophy type 2B
(MONDO_0009676)
Strong
DYSF
(HGNC:3097)
distal myopathy with anterior tibial onset
(MONDO_0011721)
Definitive
DYSF
(HGNC:3097)
Miyoshi myopathy
(MONDO_0009685)
Definitive
DYSF
(HGNC:3097)
autosomal recessive limb-girdle muscular dystrophy
(MONDO_0015152)
Strong
DYSF
(HGNC:3097)
qualitative or quantitative defects of dysferlin
(MONDO_0016145)
Definitive
TOR1A
(HGNC:3098)
early-onset generalized limb-onset dystonia
(MONDO_0007492)
Definitive
GREB1L
(HGNC:31042)
bilateral renal agenesis
(MONDO_0015986)
Limited
GREB1L
(HGNC:31042)
renal agenesis, unilateral
(MONDO_0019636)
Limited
GREB1L
(HGNC:31042)
renal hypodysplasia/aplasia 3
(MONDO_0024520)
Strong
GREB1L
(HGNC:31042)
hearing loss, autosomal dominant 80
(MONDO_0030998)
Moderate
LEFTY2
(HGNC:3122)
congenital heart disease
(MONDO_0005453)
Limited
LEFTY2
(HGNC:3122)
visceral heterotaxy
(MONDO_0018677)
Limited
GPR179
(HGNC:31371)
congenital stationary night blindness
(MONDO_0016293)
Definitive
WDR37
(HGNC:31406)
neurooculocardiogenitourinary syndrome
(MONDO_0032850)
Strong
TYMP
(HGNC:3148)
mitochondrial disease
(MONDO_0044970)
Strong
EDA
(HGNC:3157)
tooth agenesis
(MONDO_0005486)
Strong
ECHS1
(HGNC:3151)
mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency
(MONDO_0014563)
Definitive
AFG3L2
(HGNC:315)
spinocerebellar ataxia type 28
(MONDO_0012450)
Definitive
SAMD12
(HGNC:31750)
epilepsy, familial adult myoclonic, 1
(MONDO_0010985)
Limited
AFG3L2
(HGNC:315)
spastic ataxia 5
(MONDO_0013776)
Moderate
EDN1
(HGNC:3176)
auriculocondylar syndrome
(MONDO_0000107)
Limited
SAMD12
(HGNC:31750)
benign adult familial myoclonic epilepsy
(MONDO_0019448)
Definitive
EDN3
(HGNC:3178)
Waardenburg syndrome
(MONDO_0018094)
Limited
EDNRA
(HGNC:3179)
cystic fibrosis
(MONDO_0009061)
Limited
EDNRA
(HGNC:3179)
mandibulofacial dysostosis with alopecia
(MONDO_0014608)
Strong
EDNRB
(HGNC:3180)
ABCD syndrome
(MONDO_0010895)
Limited
EED
(HGNC:3188)
Weaver syndrome
(MONDO_0010193)
Strong
EED
(HGNC:3188)
Cohen-Gibson syndrome
(MONDO_0060510)
Strong
LCA5
(HGNC:31923)
severe early-childhood-onset retinal dystrophy
(MONDO_0009549)
Strong
LCA5
(HGNC:31923)
Leber congenital amaurosis
(MONDO_0018998)
Strong
CEACAM16
(HGNC:31948)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Strong
ACAN
(HGNC:319)
spondyloepiphyseal dysplasia, Kimberley type
(MONDO_0012019)
Moderate
ACAN
(HGNC:319)
spondyloepimetaphyseal dysplasia, aggrecan type
(MONDO_0013014)
Moderate
ACAN
(HGNC:319)
osteochondritis dissecans
(MONDO_0017178)
Strong
EEF2
(HGNC:3214)
spinocerebellar ataxia type 26
(MONDO_0012246)
Strong
EEF2
(HGNC:3214)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
EFEMP1
(HGNC:3218)
Doyne honeycomb retinal dystrophy
(MONDO_0007471)
Definitive
EFEMP2
(HGNC:3219)
thoracic aortic aneurysm
(MONDO_0005396)
Limited
MEGF8
(HGNC:3233)
Carpenter syndrome
(MONDO_0019012)
Strong
EGR2
(HGNC:3239)
Charcot-Marie-Tooth disease type 3
(MONDO_0007790)
Strong
EGR2
(HGNC:3239)
Charcot-Marie-Tooth disease type 4E
(MONDO_0011527)
Moderate
EGR2
(HGNC:3239)
Charcot-Marie-Tooth disease type 1D
(MONDO_0011890)
Strong
EGR2
(HGNC:3239)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
SLC38A8
(HGNC:32434)
foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome
(MONDO_0012216)
Strong
ALG11
(HGNC:32456)
ALG11-congenital disorder of glycosylation
(MONDO_0013349)
Strong
ANKDD1B
(HGNC:32525)
ankylosing spondylitis
(MONDO_0005306)
Limited
AGPAT2
(HGNC:325)
neonatal diabetes mellitus
(MONDO_0016391)
Limited
EHHADH
(HGNC:3247)
primary Fanconi syndrome
(MONDO_0007600)
Moderate
EIF2B5
(HGNC:3261)
leukoencephalopathy with vanishing white matter 5
(MONDO_0957873)
Strong
AGPAT2
(HGNC:325)
congenital generalized lipodystrophy type 1
(MONDO_0012071)
Strong
AGO2
(HGNC:3263)
Lessel-Kreienkamp syndrome
(MONDO_0030897)
Limited
EIF2S3
(HGNC:3267)
MEHMO syndrome
(MONDO_0010258)
Strong
AGO1
(HGNC:3262)
neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures
(MONDO_0859531)
Moderate
MED11
(HGNC:32687)
neurodegeneration with developmental delay, early respiratory failure, myoclonic seizures, and brain abnormalities
(MONDO_0957225)
Limited
SLCO1B7
(HGNC:32934)
schizophrenia
(MONDO_0005090)
Limited
DUOXA2
(HGNC:32698)
familial thyroid dyshormonogenesis
(MONDO_0010132)
Strong
RNF207
(HGNC:32947)
long QT syndrome
(MONDO_0002442)
Limited
SMPD4
(HGNC:32949)
neurodevelopmental disorder with microcephaly, arthrogryposis, and structural brain anomalies
(MONDO_0032838)
Moderate
ABCA2
(HGNC:32)
intellectual developmental disorder with poor growth and with or without seizures or ataxia
(MONDO_0032930)
Strong
ELANE
(HGNC:3309)
neutropenia
(MONDO_0001475)
Strong
ELN
(HGNC:3327)
supravalvular aortic stenosis
(MONDO_0008504)
Strong
AGR2
(HGNC:328)
respiratory infections, recurrent, and failure to thrive with or without diarrhea
(MONDO_0859370)
Moderate
ELANE
(HGNC:3309)
cyclic hematopoiesis
(MONDO_0008090)
Definitive
EMD
(HGNC:3331)
X-linked Emery-Dreifuss muscular dystrophy
(MONDO_0010680)
Definitive
EMX2
(HGNC:3341)
schizencephaly
(MONDO_0010011)
Disputed
ENAM
(HGNC:3344)
amelogenesis imperfecta type 1
(MONDO_0015047)
Moderate
AGRN
(HGNC:329)
congenital myasthenic syndrome 8
(MONDO_0014052)
Strong
ATRIP
(HGNC:33499)
breast cancer
(MONDO_0007254)
Strong
ENG
(HGNC:3349)
telangiectasia, hereditary hemorrhagic, type 1
(MONDO_0008535)
Definitive
ELN
(HGNC:3327)
autosomal dominant cutis laxa
(MONDO_0019571)
Definitive
CCDC103
(HGNC:32700)
primary ciliary dyskinesia
(MONDO_0016575)
Definitive
ELF4
(HGNC:3319)
autoinflammatory syndrome, familial, X-linked, Behcet-like 2
(MONDO_0024770)
Strong
ENG
(HGNC:3349)
juvenile polyposis syndrome
(MONDO_0017380)
Limited
ENPP1
(HGNC:3356)
arterial calcification, generalized, of infancy, 1
(MONDO_0008817)
Strong
NDUFAF8
(HGNC:33551)
Leigh syndrome
(MONDO_0009723)
Moderate
ENPP1
(HGNC:3356)
autosomal recessive inherited pseudoxanthoma elasticum
(MONDO_0009925)
Strong
ENPP1
(HGNC:3356)
hypophosphatemic rickets, autosomal recessive, 2
(MONDO_0013219)
Strong
ENPP1
(HGNC:3356)
hypopigmentation-punctate palmoplantar keratoderma syndrome
(MONDO_0014227)
Strong
ENPP1
(HGNC:3356)
autosomal recessive hypophosphatemic rickets
(MONDO_0017324)
Definitive
PATL2
(HGNC:33630)
oocyte maturation defect 4
(MONDO_0021575)
Definitive
ENPP1
(HGNC:3356)
arterial calcification of infancy
(MONDO_0018870)
Definitive
MICOS13
(HGNC:33702)
mitochondrial disease
(MONDO_0044970)
Limited
CFAP221
(HGNC:33720)
primary ciliary dyskinesia
(MONDO_0016575)
Moderate
EP300
(HGNC:3373)
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency
(MONDO_0013364)
Limited
EP300
(HGNC:3373)
Rubinstein-Taybi syndrome
(MONDO_0019188)
Strong
EPB41
(HGNC:3377)
hereditary elliptocytosis
(MONDO_0017319)
Moderate
EPB42
(HGNC:3381)
hereditary spherocytosis
(MONDO_0019350)
Strong
SDHAF1
(HGNC:33867)
mitochondrial disease
(MONDO_0044970)
Strong
EPHB4
(HGNC:3395)
capillary malformation-arteriovenous malformation 2
(MONDO_0020785)
Strong
EPHB4
(HGNC:3395)
capillary malformation-arteriovenous malformation syndrome
(MONDO_0012016)
Definitive
EPHX2
(HGNC:3402)
hypercholesterolemia, familial, 1
(MONDO_0007750)
Limited
EPOR
(HGNC:3416)
primary familial polycythemia due to EPO receptor mutation
(MONDO_0007572)
Definitive
ERAL1
(HGNC:3424)
Perrault syndrome
(MONDO_0017312)
Strong
ERBB2
(HGNC:3430)
lung cancer
(MONDO_0008903)
Strong
ERBB2
(HGNC:3430)
Hirschsprung disease
(MONDO_0018309)
Moderate
ERBB3
(HGNC:3431)
Hirschsprung disease
(MONDO_0018309)
Moderate
ERBB4
(HGNC:3432)
amyotrophic lateral sclerosis
(MONDO_0004976)
Moderate
ERCC2
(HGNC:3434)
sarcoma
(MONDO_0005089)
Limited
ERCC1
(HGNC:3433)
COFS syndrome
(MONDO_0008926)
Limited
ERCC2
(HGNC:3434)
COFS syndrome
(MONDO_0008926)
Moderate
ERCC2
(HGNC:3434)
xeroderma pigmentosum group D
(MONDO_0010212)
Strong
ERCC2
(HGNC:3434)
xeroderma pigmentosum-Cockayne syndrome complex
(MONDO_0016354)
Strong
ERCC2
(HGNC:3434)
trichothiodystrophy
(MONDO_0018053)
Definitive
ERCC2
(HGNC:3434)
xeroderma pigmentosum
(MONDO_0019600)
Definitive
ERCC3
(HGNC:3435)
xeroderma pigmentosum group B
(MONDO_0012531)
Moderate
ERCC3
(HGNC:3435)
xeroderma pigmentosum-Cockayne syndrome complex
(MONDO_0016354)
Strong
ERCC3
(HGNC:3435)
trichothiodystrophy
(MONDO_0018053)
Moderate
ERCC3
(HGNC:3435)
xeroderma pigmentosum
(MONDO_0019600)
Strong
ERCC4
(HGNC:3436)
xeroderma pigmentosum group F
(MONDO_0010215)
Strong
ERCC4
(HGNC:3436)
XFE progeroid syndrome
(MONDO_0012590)
Limited
ERCC4
(HGNC:3436)
Fanconi anemia complementation group Q
(MONDO_0014108)
Strong
ERCC4
(HGNC:3436)
xeroderma pigmentosum-Cockayne syndrome complex
(MONDO_0016354)
Limited
ERCC4
(HGNC:3436)
Fanconi anemia
(MONDO_0019391)
Strong
ERCC4
(HGNC:3436)
xeroderma pigmentosum
(MONDO_0019600)
Definitive
ERCC5
(HGNC:3437)
COFS syndrome
(MONDO_0008926)
Strong
ERCC5
(HGNC:3437)
xeroderma pigmentosum-Cockayne syndrome complex
(MONDO_0016354)
Strong
ERCC5
(HGNC:3437)
xeroderma pigmentosum
(MONDO_0019600)
Definitive
PCARE
(HGNC:34383)
retinitis pigmentosa
(MONDO_0019200)
Strong
ERCC6
(HGNC:3438)
COFS syndrome
(MONDO_0008926)
Limited
ERCC6
(HGNC:3438)
UV-sensitive syndrome
(MONDO_0015797)
Limited
ERCC6
(HGNC:3438)
Cockayne syndrome type 2
(MONDO_0019570)
Definitive
ERCC8
(HGNC:3439)
UV-sensitive syndrome
(MONDO_0015797)
Limited
ERCC8
(HGNC:3439)
Cockayne syndrome type 1
(MONDO_0019569)
Definitive
ERCC8
(HGNC:3439)
Cockayne syndrome type 2
(MONDO_0019570)
Disputed
ERF
(HGNC:3444)
craniosynostosis 4
(MONDO_0010929)
Limited
ERF
(HGNC:3444)
Chitayat syndrome
(MONDO_0014956)
Strong
ESR2
(HGNC:3468)
familial medullary thyroid carcinoma
(MONDO_0007958)
Limited
ESR1
(HGNC:3467)
estrogen resistance syndrome
(MONDO_0014148)
Moderate
ESRRB
(HGNC:3473)
autosomal recessive nonsyndromic hearing loss 35
(MONDO_0012060)
Moderate
ETFB
(HGNC:3482)
multiple acyl-CoA dehydrogenase deficiency
(MONDO_0009282)
Strong
ETS1
(HGNC:3488)
congenital heart disease
(MONDO_0005453)
Limited
ETS1
(HGNC:3488)
systemic lupus erythematosus
(MONDO_0007915)
Strong
AHR
(HGNC:348)
foveal hypoplasia
(MONDO_0044203)
Limited
ETV6
(HGNC:3495)
thrombocytopenia 5
(MONDO_0014536)
Definitive
EVC
(HGNC:3497)
acrofacial dysostosis, Weyers type
(MONDO_0008673)
Limited
MECOM
(HGNC:3498)
radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome
(MONDO_0011555)
Moderate
MECOM
(HGNC:3498)
radioulnar synostosis with amegakaryocytic thrombocytopenia 2
(MONDO_0014758)
Strong
ABCA4
(HGNC:34)
severe early-childhood-onset retinal dystrophy
(MONDO_0009549)
Definitive
ABCA4
(HGNC:34)
cone-rod dystrophy
(MONDO_0015993)
Strong
ABCA4
(HGNC:34)
retinitis pigmentosa
(MONDO_0019200)
Definitive
ABCA4
(HGNC:34)
Stargardt disease
(MONDO_0019353)
Definitive
EWSR1
(HGNC:3508)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
EXO1
(HGNC:3511)
Lynch syndrome
(MONDO_0005835)
Limited
BHLHA9
(HGNC:35126)
mesoaxial synostotic syndactyly with phalangeal reduction
(MONDO_0012271)
Strong
EXT1
(HGNC:3512)
chondrosarcoma
(MONDO_0008977)
Moderate
EXT2
(HGNC:3513)
seizures-scoliosis-macrocephaly syndrome
(MONDO_0014731)
Strong
EXTL3
(HGNC:3518)
immunoskeletal dysplasia with neurodevelopmental abnormalities
(MONDO_0044312)
Limited
EYA4
(HGNC:3522)
autosomal dominant nonsyndromic hearing loss 10
(MONDO_0011031)
Strong
EZH2
(HGNC:3527)
Weaver syndrome
(MONDO_0010193)
Definitive
F11
(HGNC:3529)
congenital factor XI deficiency
(MONDO_0012897)
Strong
F12
(HGNC:3530)
congenital factor XII deficiency
(MONDO_0009315)
Definitive
F12
(HGNC:3530)
hereditary angioedema type 3
(MONDO_0012526)
Moderate
F13B
(HGNC:3534)
factor XIII, b subunit, deficiency of
(MONDO_0013190)
Limited
F13B
(HGNC:3534)
congenital factor XIII deficiency
(MONDO_0018029)
Limited
F2
(HGNC:3535)
congenital prothrombin deficiency
(MONDO_0013361)
Moderate
F5
(HGNC:3542)
thrombophilia due to activated protein C resistance
(MONDO_0008560)
Definitive
F5
(HGNC:3542)
congenital factor V deficiency
(MONDO_0009210)
Definitive
F8
(HGNC:3546)
hemophilia A
(MONDO_0010602)
Definitive
F8
(HGNC:3546)
severe hemophilia A
(MONDO_0015719)
Definitive
F8
(HGNC:3546)
mild hemophilia A
(MONDO_0015721)
Definitive
F9
(HGNC:3551)
severe hemophilia B
(MONDO_0015715)
Strong
ACSL4
(HGNC:3571)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Moderate
BPTF
(HGNC:3581)
neurodevelopmental disorder with dysmorphic facies and distal limb anomalies
(MONDO_0060596)
Strong
FANCB
(HGNC:3583)
Fanconi anemia
(MONDO_0019391)
Strong
FANCA
(HGNC:3582)
Fanconi anemia
(MONDO_0019391)
Definitive
FANCC
(HGNC:3584)
colorectal cancer
(MONDO_0005575)
Limited
FANCC
(HGNC:3584)
breast cancer
(MONDO_0007254)
Limited
FANCC
(HGNC:3584)
ovarian cancer
(MONDO_0008170)
Limited
FANCC
(HGNC:3584)
prostate cancer
(MONDO_0008315)
Limited
FANCC
(HGNC:3584)
Fanconi anemia complementation group C
(MONDO_0009213)
Moderate
FANCC
(HGNC:3584)
Fanconi anemia
(MONDO_0019391)
Definitive
FANCD2
(HGNC:3585)
Fanconi anemia
(MONDO_0019391)
Definitive
FANCE
(HGNC:3586)
Fanconi anemia
(MONDO_0019391)
Definitive
FANCF
(HGNC:3587)
Fanconi anemia
(MONDO_0019391)
Definitive
FANCG
(HGNC:3588)
Fanconi anemia
(MONDO_0019391)
Definitive
AIP
(HGNC:358)
familial isolated pituitary adenoma
(MONDO_0017824)
Strong
AIP
(HGNC:358)
acromegaly
(MONDO_0019933)
Strong
AIP
(HGNC:358)
pituitary gigantism
(MONDO_0020479)
Strong
AIPL1
(HGNC:359)
Leber congenital amaurosis 4
(MONDO_0011458)
Strong
FBLN2
(HGNC:3601)
pulmonary arterial hypertension
(MONDO_0015924)
Limited
AIPL1
(HGNC:359)
Leber congenital amaurosis
(MONDO_0018998)
Definitive
FBN1
(HGNC:3603)
geleophysic dysplasia
(MONDO_0000127)
Strong
FBN1
(HGNC:3603)
Shprintzen-Goldberg syndrome
(MONDO_0008426)
Limited
FBN1
(HGNC:3603)
stiff skin syndrome
(MONDO_0008492)
Limited
FBN1
(HGNC:3603)
Acromicric dysplasia
(MONDO_0007055)
Strong
FBN1
(HGNC:3603)
Marfan syndrome
(MONDO_0007947)
Definitive
FBN1
(HGNC:3603)
progeroid and marfanoid aspect-lipodystrophy syndrome
(MONDO_0014831)
Limited
FBN1
(HGNC:3603)
familial thoracic aortic aneurysm and aortic dissection
(MONDO_0019625)
Strong
FBN1
(HGNC:3603)
isolated ectopia lentis
(MONDO_0015998)
Strong
FGA
(HGNC:3661)
congenital afibrinogenemia
(MONDO_0008737)
Definitive
FGA
(HGNC:3661)
familial dysfibrinogenemia
(MONDO_0014452)
Strong
FGA
(HGNC:3661)
congenital fibrinogen deficiency
(MONDO_0018060)
Definitive
FGA
(HGNC:3661)
AFib amyloidosis
(MONDO_0019733)
Moderate
FGB
(HGNC:3662)
congenital afibrinogenemia
(MONDO_0008737)
Strong
FGB
(HGNC:3662)
familial dysfibrinogenemia
(MONDO_0014452)
Strong
FGF10
(HGNC:3666)
LADD syndrome
(MONDO_0007872)
Strong
FGF10
(HGNC:3666)
aplasia of lacrimal and salivary glands
(MONDO_0008397)
Definitive
FGA
(HGNC:3661)
familial visceral amyloidosis
(MONDO_0007099)
Limited
FGF10
(HGNC:3666)
craniosynostosis
(MONDO_0015469)
Limited
FGF12
(HGNC:3668)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
FGF16
(HGNC:3672)
syndactyly type 8
(MONDO_0010669)
Moderate
FGF17
(HGNC:3673)
Kallmann syndrome
(MONDO_0018800)
Limited
FGF3
(HGNC:3681)
deafness with labyrinthine aplasia, microtia, and microdontia
(MONDO_0012541)
Strong
FGF8
(HGNC:3686)
holoprosencephaly
(MONDO_0016296)
Moderate
FGF8
(HGNC:3686)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
FGF8
(HGNC:3686)
Kallmann syndrome
(MONDO_0018800)
Moderate
FKTN
(HGNC:3622)
dilated cardiomyopathy 1X
(MONDO_0012704)
Limited
FKTN
(HGNC:3622)
autosomal recessive limb-girdle muscular dystrophy type 2M
(MONDO_0012699)
Limited
FBN1
(HGNC:3603)
Weill-Marchesani syndrome
(MONDO_0018096)
Strong
AK2
(HGNC:362)
reticular dysgenesis
(MONDO_0009973)
Strong
FGA
(HGNC:3661)
thrombophilia
(MONDO_0002305)
Limited
FBN1
(HGNC:3603)
neonatal Marfan syndrome
(MONDO_0017309)
Definitive
FGFR1
(HGNC:3688)
Jackson-Weiss syndrome
(MONDO_0007400)
Limited
FGFR1
(HGNC:3688)
Pfeiffer syndrome
(MONDO_0007043)
Definitive
FGFR1
(HGNC:3688)
tooth agenesis
(MONDO_0005486)
Limited
FKTN
(HGNC:3622)
muscle-eye-brain disease
(MONDO_0018939)
Strong
FCGR2B
(HGNC:3618)
systemic lupus erythematosus
(MONDO_0007915)
Strong
FGFR1
(HGNC:3688)
osteoglophonic dwarfism
(MONDO_0008150)
Strong
FGF9
(HGNC:3687)
multiple synostoses syndrome
(MONDO_0017923)
Strong
FCGR3B
(HGNC:3620)
systemic lupus erythematosus
(MONDO_0007915)
Limited
AIRE
(HGNC:360)
autoimmune polyendocrine syndrome type 1
(MONDO_0009411)
Definitive
FGFR1
(HGNC:3688)
encephalocraniocutaneous lipomatosis
(MONDO_0013074)
Strong
FGFR1
(HGNC:3688)
septooptic dysplasia
(MONDO_0008428)
Limited
FGFR1
(HGNC:3688)
holoprosencephaly
(MONDO_0016296)
Moderate
FGFR1
(HGNC:3688)
Hartsfield-Bixler-Demyer syndrome
(MONDO_0014196)
Strong
FGFR1
(HGNC:3688)
Kallmann syndrome
(MONDO_0018800)
Definitive
FGFR1
(HGNC:3688)
hypogonadotropic hypogonadism
(MONDO_0018555)
Definitive
FGFR2
(HGNC:3689)
Saethre-Chotzen syndrome
(MONDO_0007042)
Limited
FGFR2
(HGNC:3689)
Apert syndrome
(MONDO_0007041)
Definitive
FGFR2
(HGNC:3689)
Beare-Stevenson cutis gyrata syndrome
(MONDO_0007412)
Strong
FGFR2
(HGNC:3689)
Pfeiffer syndrome
(MONDO_0007043)
Definitive
FGFR2
(HGNC:3689)
Crouzon syndrome
(MONDO_0007405)
Definitive
FGFR2
(HGNC:3689)
Antley-Bixler syndrome
(MONDO_0008803)
Strong
FGFR2
(HGNC:3689)
Pfeiffer syndrome type 2
(MONDO_0019660)
Moderate
FGFR2
(HGNC:3689)
LADD syndrome
(MONDO_0007872)
Moderate
FGFR2
(HGNC:3689)
Pfeiffer syndrome type 1
(MONDO_0019659)
Definitive
FGFR3
(HGNC:3690)
Achondroplasia
(MONDO_0007037)
Definitive
FGFR3
(HGNC:3690)
hypochondroplasia
(MONDO_0007793)
Definitive
FGFR2
(HGNC:3689)
Jackson-Weiss syndrome
(MONDO_0007400)
Strong
FGFR3
(HGNC:3690)
thanatophoric dysplasia type 1
(MONDO_0008546)
Definitive
FGFR3
(HGNC:3690)
LADD syndrome
(MONDO_0007872)
Moderate
FGFR3
(HGNC:3690)
Muenke syndrome
(MONDO_0011274)
Definitive
FGFR3
(HGNC:3690)
Crouzon syndrome-acanthosis nigricans syndrome
(MONDO_0012833)
Definitive
FGFR3
(HGNC:3690)
camptodactyly-tall stature-scoliosis-hearing loss syndrome
(MONDO_0012504)
Moderate
FGG
(HGNC:3694)
thrombophilia
(MONDO_0002305)
Limited
FGFR3
(HGNC:3690)
severe achondroplasia-developmental delay-acanthosis nigricans syndrome
(MONDO_0014658)
Strong
FGG
(HGNC:3694)
congenital fibrinogen deficiency
(MONDO_0018060)
Strong
FH
(HGNC:3700)
leiomyosarcoma
(MONDO_0005058)
Limited
FH
(HGNC:3700)
hereditary leiomyomatosis and renal cell cancer
(MONDO_0007888)
Definitive
FIBP
(HGNC:3705)
tall stature-intellectual disability-renal anomalies syndrome
(MONDO_0014918)
Limited
FH
(HGNC:3700)
fumaric aciduria
(MONDO_0011730)
Definitive
FHL1
(HGNC:3702)
X-linked myopathy with postural muscle atrophy
(MONDO_0010401)
Strong
ATP8B1
(HGNC:3706)
progressive familial intrahepatic cholestasis type 1
(MONDO_0008892)
Definitive
CRPPA
(HGNC:37276)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Definitive
KLLN
(HGNC:37212)
Cowden disease
(MONDO_0016063)
Limited
TMEM231
(HGNC:37234)
Meckel syndrome
(MONDO_0018921)
Definitive
FLNA
(HGNC:3754)
otopalatodigital syndrome type 2
(MONDO_0010571)
Strong
FLNA
(HGNC:3754)
Melnick-Needles syndrome
(MONDO_0010650)
Definitive
FLNA
(HGNC:3754)
congenital short bowel syndrome
(MONDO_0014097)
Limited
FLNA
(HGNC:3754)
periventricular nodular heterotopia
(MONDO_0020341)
Definitive
FLNB
(HGNC:3755)
atelosteogenesis type I
(MONDO_0007167)
Strong
FLNA
(HGNC:3754)
frontometaphyseal dysplasia
(MONDO_0015942)
Definitive
FLNB
(HGNC:3755)
atelosteogenesis type III
(MONDO_0007168)
Strong
FLNB
(HGNC:3755)
Larsen syndrome
(MONDO_0007875)
Definitive
FLNC
(HGNC:3756)
dilated cardiomyopathy
(MONDO_0005021)
Strong
FLNB
(HGNC:3755)
Boomerang dysplasia
(MONDO_0007208)
Strong
FLNB
(HGNC:3755)
spondylocarpotarsal synostosis syndrome
(MONDO_0010094)
Definitive
FLNC
(HGNC:3756)
myofibrillar myopathy 5
(MONDO_0012289)
Strong
FMR1
(HGNC:3775)
fragile X-associated tremor/ataxia syndrome
(MONDO_0010382)
Definitive
FLRT3
(HGNC:3762)
Kallmann syndrome
(MONDO_0018800)
Limited
FMR1
(HGNC:3775)
fragile X syndrome
(MONDO_0010383)
Definitive
FOLR1
(HGNC:3791)
neurodegenerative syndrome due to cerebral folate transport deficiency
(MONDO_0013110)
Definitive
AFF2
(HGNC:3776)
FRAXE intellectual disability
(MONDO_0010659)
Limited
AKAP9
(HGNC:379)
long QT syndrome
(MONDO_0002442)
Limited
FMR1
(HGNC:3775)
premature ovarian failure 1
(MONDO_0010706)
Moderate
FLT4
(HGNC:3767)
tetralogy of fallot
(MONDO_0008542)
Strong
FOXC1
(HGNC:3800)
aniridia
(MONDO_0019172)
Limited
FOXC1
(HGNC:3800)
Peters anomaly
(MONDO_0011414)
Limited
FOXC1
(HGNC:3800)
Axenfeld-Rieger syndrome
(MONDO_0019187)
Definitive
FOXC1
(HGNC:3800)
Rieger anomaly
(MONDO_0019628)
Strong
FOXD3
(HGNC:3804)
aniridia
(MONDO_0019172)
Limited
FOXC1
(HGNC:3800)
Axenfeld anomaly
(MONDO_0020368)
Definitive
FOXD3
(HGNC:3804)
anterior segment dysgenesis
(MONDO_0019503)
Limited
FOXE1
(HGNC:3806)
Bamforth-Lazarus syndrome
(MONDO_0009437)
Moderate
FOXE3
(HGNC:3808)
cataract
(MONDO_0005129)
Moderate
FOXE3
(HGNC:3808)
congenital primary aphakia
(MONDO_0012456)
Limited
FOXE3
(HGNC:3808)
Peters anomaly
(MONDO_0011414)
Moderate
FOXI1
(HGNC:3815)
hearing loss disorder
(MONDO_0005365)
Limited
FOXE3
(HGNC:3808)
anterior segment dysgenesis
(MONDO_0019503)
Strong
FOXI1
(HGNC:3815)
Pendred syndrome
(MONDO_0010134)
Limited
FOXI1
(HGNC:3815)
autosomal recessive nonsyndromic hearing loss 4
(MONDO_0010933)
Limited
FOXJ1
(HGNC:3816)
primary ciliary dyskinesia
(MONDO_0016575)
Strong
FOXP1
(HGNC:3823)
congenital heart disease
(MONDO_0005453)
Limited
AKT1
(HGNC:391)
Cowden disease
(MONDO_0016063)
Limited
AKT1
(HGNC:391)
Proteus syndrome
(MONDO_0008318)
Definitive
AKT2
(HGNC:392)
type 2 diabetes mellitus
(MONDO_0005148)
Moderate
AKT3
(HGNC:393)
microcephaly
(MONDO_0001149)
Moderate
MTOR
(HGNC:3942)
macrocephaly-intellectual disability-neurodevelopmental disorder-small thorax syndrome
(MONDO_0014716)
Definitive
PRSS56
(HGNC:39433)
nanophthalmia
(MONDO_0005514)
Strong
ALAD
(HGNC:395)
porphyria due to ALA dehydratase deficiency
(MONDO_0013000)
Strong
FSCN2
(HGNC:3960)
retinitis pigmentosa
(MONDO_0019200)
Limited
FSHB
(HGNC:3964)
hypogonadotropic hypogonadism 24 without anosmia
(MONDO_0009239)
Moderate
FSHR
(HGNC:3969)
ovarian hyperstimulation syndrome
(MONDO_0011972)
Strong
FTCD
(HGNC:3974)
formiminoglutamic aciduria
(MONDO_0009240)
Strong
PET100
(HGNC:40038)
Leigh syndrome
(MONDO_0009723)
Strong
FUS
(HGNC:4010)
amyotrophic lateral sclerosis
(MONDO_0004976)
Definitive
FUS
(HGNC:4010)
amyotrophic lateral sclerosis type 6
(MONDO_0011951)
Strong
FUS
(HGNC:4010)
juvenile amyotrophic lateral sclerosis
(MONDO_0017593)
Definitive
KDSR
(HGNC:4021)
erythrokeratodermia variabilis
(MONDO_0017851)
Moderate
FXR1
(HGNC:4023)
congenital myopathy
(MONDO_0019952)
Strong
ALDH3A2
(HGNC:403)
Sjogren-Larsson syndrome
(MONDO_0010031)
Definitive
FZD4
(HGNC:4042)
persistent hyperplastic primary vitreous
(MONDO_0019631)
Limited
XRCC6
(HGNC:4055)
autism spectrum disorder
(MONDO_0005258)
Limited
FZD2
(HGNC:4040)
autosomal dominant omodysplasia
(MONDO_0008123)
Moderate
G6PC1
(HGNC:4056)
glycogen storage disease due to glucose-6-phosphatase deficiency type IA
(MONDO_0009287)
Definitive
GAA
(HGNC:4065)
glycogen storage disease II
(MONDO_0009290)
Definitive
G6PD
(HGNC:4057)
G6PD deficiency
(MONDO_0005775)
Definitive
GABRA1
(HGNC:4075)
juvenile myoclonic epilepsy
(MONDO_0009696)
Limited
GABRA1
(HGNC:4075)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
GABRB1
(HGNC:4081)
developmental and epileptic encephalopathy, 45
(MONDO_0014942)
Moderate
GABRB3
(HGNC:4083)
childhood absence epilepsy
(MONDO_0010826)
Moderate
GABRB3
(HGNC:4083)
developmental and epileptic encephalopathy, 43
(MONDO_0014921)
Strong
GABRB3
(HGNC:4083)
Lennox-Gastaut syndrome
(MONDO_0016532)
Strong
GABRB3
(HGNC:4083)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
GABRD
(HGNC:4084)
epilepsy
(MONDO_0005027)
Limited
GABRG2
(HGNC:4087)
epilepsy
(MONDO_0005027)
Strong
GABRG2
(HGNC:4087)
childhood epilepsy with centrotemporal spikes
(MONDO_0007295)
Moderate
GAD1
(HGNC:4092)
developmental and epileptic encephalopathy 89
(MONDO_0030856)
Limited
GABRG2
(HGNC:4087)
generalized epilepsy with febrile seizures plus
(MONDO_0018214)
Moderate
GALE
(HGNC:4116)
galactose epimerase deficiency
(MONDO_0009257)
Strong
GALK1
(HGNC:4118)
galactokinase deficiency
(MONDO_0009255)
Definitive
B4GALNT1
(HGNC:4117)
hereditary spastic paraplegia 26
(MONDO_0012213)
Strong
GANAB
(HGNC:4138)
autosomal dominant polycystic kidney disease
(MONDO_0004691)
Moderate
GAN
(HGNC:4137)
giant axonal neuropathy 1
(MONDO_0009749)
Strong
ALDOA
(HGNC:414)
glycogen storage disease due to aldolase A deficiency
(MONDO_0012747)
Limited
GARS1
(HGNC:4162)
Charcot-Marie-Tooth disease type 2D
(MONDO_0011091)
Definitive
GAS1
(HGNC:4165)
holoprosencephaly
(MONDO_0016296)
Limited
GAS8
(HGNC:4166)
primary ciliary dyskinesia
(MONDO_0016575)
Definitive
GAS2
(HGNC:4167)
hearing loss disorder
(MONDO_0005365)
Strong
GATA1
(HGNC:4170)
cutaneous porphyria
(MONDO_0009902)
Limited
GATA1
(HGNC:4170)
Diamond-Blackfan anemia
(MONDO_0015253)
Strong
GATA1
(HGNC:4170)
GATA1-Related X-Linked Cytopenia
(MONDO_0100089)
Definitive
GATA2
(HGNC:4171)
deafness-lymphedema-leukemia syndrome
(MONDO_0013540)
Definitive
GATA2
(HGNC:4171)
monocytopenia with susceptibility to infections
(MONDO_0013607)
Definitive
GATA2
(HGNC:4171)
myelodysplastic syndrome
(MONDO_0018881)
Strong
GATA3
(HGNC:4172)
hypoparathyroidism-deafness-renal disease syndrome
(MONDO_0007797)
Definitive
GATA4
(HGNC:4173)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
GATA4
(HGNC:4173)
tetralogy of fallot
(MONDO_0008542)
Limited
GATA4
(HGNC:4173)
neonatal diabetes mellitus
(MONDO_0016391)
Limited
GATA6
(HGNC:4174)
tetralogy of fallot
(MONDO_0008542)
Strong
GATA6
(HGNC:4174)
neonatal diabetes mellitus
(MONDO_0016391)
Definitive
GATA6
(HGNC:4174)
conotruncal heart malformations
(MONDO_0016581)
Strong
GATM
(HGNC:4175)
primary Fanconi syndrome
(MONDO_0007600)
Moderate
GATM
(HGNC:4175)
Fanconi renotubular syndrome 1
(MONDO_0024525)
Limited
GATM
(HGNC:4175)
AGAT deficiency
(MONDO_0012996)
Definitive
GBA1
(HGNC:4177)
Parkinson disease
(MONDO_0005180)
Strong
GBA1
(HGNC:4177)
Gaucher disease type I
(MONDO_0009265)
Definitive
GBA1
(HGNC:4177)
Gaucher disease type II
(MONDO_0009266)
Strong
GBA1
(HGNC:4177)
Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome
(MONDO_0009268)
Limited
GBA1
(HGNC:4177)
Gaucher disease perinatal lethal
(MONDO_0011945)
Moderate
GBA1
(HGNC:4177)
Gaucher disease
(MONDO_0018150)
Definitive
GBA1
(HGNC:4177)
Gaucher disease type III
(MONDO_0009267)
Definitive
GCH1
(HGNC:4193)
GTP cyclohydrolase I deficiency
(MONDO_0100184)
Strong
GCGR
(HGNC:4192)
GCGR-related hyperglucagonemia
(MONDO_0018582)
Strong
GCK
(HGNC:4195)
maturity-onset diabetes of the young type 2
(MONDO_0007453)
Definitive
GCK
(HGNC:4195)
monogenic diabetes
(MONDO_0015967)
Definitive
GCK
(HGNC:4195)
maturity-onset diabetes of the young
(MONDO_0018911)
Definitive
GCK
(HGNC:4195)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Definitive
GCM2
(HGNC:4198)
familial isolated hyperparathyroidism
(MONDO_0015027)
Strong
OPN1MW
(HGNC:4206)
blue cone monochromacy
(MONDO_0010563)
Definitive
GCSH
(HGNC:4208)
glycine encephalopathy
(MONDO_0011612)
Moderate
GDF1
(HGNC:4214)
right atrial isomerism
(MONDO_0008832)
Strong
GDF2
(HGNC:4217)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
GDF2
(HGNC:4217)
hereditary hemorrhagic telangiectasia
(MONDO_0019180)
Strong
GDF5
(HGNC:4220)
Angel-shaped phalango-epiphyseal dysplasia
(MONDO_0007114)
Limited
GDF5
(HGNC:4220)
brachydactyly type A1
(MONDO_0007215)
Moderate
GDF5
(HGNC:4220)
brachydactyly type A2
(MONDO_0007216)
Moderate
GDF5
(HGNC:4220)
brachydactyly type C
(MONDO_0007221)
Strong
GDF5
(HGNC:4220)
proximal symphalangism
(MONDO_0008511)
Strong
GDF5
(HGNC:4220)
acromesomelic dysplasia 2C, Hunter-Thompson type
(MONDO_0008717)
Limited
GDF5
(HGNC:4220)
acromesomelic dysplasia 2B
(MONDO_0009231)
Strong
GDF6
(HGNC:4221)
microphthalmia
(MONDO_0021129)
Limited
GDF6
(HGNC:4221)
multiple synostoses syndrome 4
(MONDO_0054752)
Moderate
GDI1
(HGNC:4226)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Limited
GFI1B
(HGNC:4238)
platelet storage pool deficiency
(MONDO_0008495)
Moderate
GGCX
(HGNC:4247)
body skin hyperlaxity due to vitamin K-dependent coagulation factor deficiency
(MONDO_0012570)
Moderate
GGCX
(HGNC:4247)
pulmonary arterial hypertension
(MONDO_0015924)
Moderate
GH1
(HGNC:4261)
isolated growth hormone deficiency type II
(MONDO_0008250)
Definitive
GJA1
(HGNC:4274)
autosomal dominant palmoplantar keratoderma and congenital alopecia
(MONDO_0007083)
Moderate
GJA1
(HGNC:4274)
oculodentodigital dysplasia
(MONDO_0008111)
Definitive
GJA1
(HGNC:4274)
Hallermann-Streiff syndrome
(MONDO_0009318)
Limited
GJA1
(HGNC:4274)
craniometaphyseal dysplasia
(MONDO_0015465)
Moderate
GJA1
(HGNC:4274)
erythrokeratodermia variabilis
(MONDO_0017851)
Limited
GJA5
(HGNC:4279)
familial atrial fibrillation
(MONDO_0018054)
Moderate
GJB1
(HGNC:4283)
Charcot-Marie-Tooth disease X-linked dominant 1
(MONDO_0010549)
Definitive
GJB2
(HGNC:4284)
palmoplantar keratoderma-deafness syndrome
(MONDO_0007852)
Limited
GJB2
(HGNC:4284)
keratoderma hereditarium mutilans
(MONDO_0007422)
Strong
GJB2
(HGNC:4284)
autosomal dominant keratitis-ichthyosis-hearing loss syndrome
(MONDO_0007850)
Strong
GJB2
(HGNC:4284)
Bart-Pumphrey syndrome
(MONDO_0007866)
Limited
GJB2
(HGNC:4284)
KID syndrome
(MONDO_0018781)
Strong
GJB2
(HGNC:4284)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Definitive
GJB3
(HGNC:4285)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Limited
GJB4
(HGNC:4286)
erythrokeratodermia variabilis
(MONDO_0017851)
Strong
GJB6
(HGNC:4288)
KID syndrome
(MONDO_0018781)
Limited
GLA
(HGNC:4296)
Fabry disease
(MONDO_0010526)
Definitive
GLB1
(HGNC:4298)
GM1 gangliosidosis type 1
(MONDO_0009260)
Strong
GLB1
(HGNC:4298)
mucopolysaccharidosis type 4B
(MONDO_0009660)
Strong
GLB1
(HGNC:4298)
GM1 gangliosidosis
(MONDO_0018149)
Definitive
ABCB11
(HGNC:42)
progressive familial intrahepatic cholestasis type 2
(MONDO_0011156)
Definitive
ABCB11
(HGNC:42)
benign recurrent intrahepatic cholestasis type 2
(MONDO_0011559)
Strong
ALOX12B
(HGNC:430)
self-healing collodion baby
(MONDO_0017267)
Strong
ALOX12B
(HGNC:430)
lamellar ichthyosis
(MONDO_0017778)
Definitive
GCLC
(HGNC:4311)
cystic fibrosis
(MONDO_0009061)
Limited
ALOX12B
(HGNC:430)
congenital non-bullous ichthyosiform erythroderma
(MONDO_0019306)
Definitive
GCLC
(HGNC:4311)
gamma-glutamylcysteine synthetase deficiency
(MONDO_0009259)
Strong
GLE1
(HGNC:4315)
amyotrophic lateral sclerosis
(MONDO_0004976)
Moderate
GLE1
(HGNC:4315)
lethal congenital contracture syndrome 1
(MONDO_0009670)
Moderate
GLE1
(HGNC:4315)
lethal arthrogryposis-anterior horn cell disease syndrome
(MONDO_0012750)
Moderate
GLI1
(HGNC:4317)
Ellis-van Creveld syndrome
(MONDO_0009162)
Strong
GLI2
(HGNC:4318)
postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome
(MONDO_0014369)
Limited
GLI2
(HGNC:4318)
holoprosencephaly
(MONDO_0016296)
Limited
GLI3
(HGNC:4319)
Pallister-Hall syndrome
(MONDO_0007804)
Definitive
GLI3
(HGNC:4319)
polysyndactyly 4
(MONDO_0008272)
Limited
GLI3
(HGNC:4319)
Greig cephalopolysyndactyly syndrome
(MONDO_0008287)
Definitive
GLI3
(HGNC:4319)
acrocallosal syndrome
(MONDO_0008708)
Limited
BICRA
(HGNC:4332)
Coffin-Siris syndrome 12
(MONDO_0025699)
Limited
GLRB
(HGNC:4329)
hereditary hyperekplexia
(MONDO_0021022)
Strong
GM2A
(HGNC:4367)
Tay-Sachs disease AB variant
(MONDO_0010099)
Moderate
GNA11
(HGNC:4379)
familial hypocalciuric hypercalcemia 2
(MONDO_0007792)
Strong
GNA11
(HGNC:4379)
autosomal dominant hypocalcemia 2
(MONDO_0014146)
Strong
GNA11
(HGNC:4379)
autosomal dominant hypocalcemia
(MONDO_0018543)
Strong
GNA11
(HGNC:4379)
congenital hemangioma
(MONDO_0018715)
Moderate
GNAI3
(HGNC:4387)
auriculocondylar syndrome 1
(MONDO_0011234)
Definitive
GNAL
(HGNC:4388)
dystonia 25
(MONDO_0014033)
Strong
GNAO1
(HGNC:4389)
movement disorder
(MONDO_0005395)
Definitive
GNAO1
(HGNC:4389)
developmental and epileptic encephalopathy, 17
(MONDO_0014199)
Strong
GNAO1
(HGNC:4389)
neurodevelopmental disorder with involuntary movements
(MONDO_0060491)
Strong
GNAO1
(HGNC:4389)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
ALPL
(HGNC:438)
perinatal lethal hypophosphatasia
(MONDO_0016605)
Definitive
ALPL
(HGNC:438)
odontohypophosphatasia
(MONDO_0016607)
Limited
GNAQ
(HGNC:4390)
congenital hemangioma
(MONDO_0018715)
Limited
GNAQ
(HGNC:4390)
Sturge-Weber syndrome
(MONDO_0008501)
Definitive
GNAS
(HGNC:4392)
pseudohypoparathyroidism type 1A
(MONDO_0007078)
Strong
GNAS
(HGNC:4392)
progressive osseous heteroplasia
(MONDO_0008153)
Strong
GNAS
(HGNC:4392)
pseudohypoparathyroidism type 1B
(MONDO_0011301)
Strong
GNAS
(HGNC:4392)
pseudohypoparathyroidism type 1C
(MONDO_0012911)
Moderate
GNAS
(HGNC:4392)
pseudopseudohypoparathyroidism
(MONDO_0012912)
Definitive
GNAS
(HGNC:4392)
McCune-Albright syndrome
(MONDO_0018919)
Definitive
GNAT2
(HGNC:4394)
achromatopsia
(MONDO_0018852)
Strong
GNB3
(HGNC:4400)
congenital stationary night blindness
(MONDO_0016293)
Strong
GNMT
(HGNC:4415)
glycine N-methyltransferase deficiency
(MONDO_0011698)
Limited
GNB5
(HGNC:4401)
gnb5-related intellectual disability-cardiac arrhythmia syndrome
(MONDO_0014953)
Moderate
GNPAT
(HGNC:4416)
rhizomelic chondrodysplasia punctata type 2
(MONDO_0009112)
Strong
GNRH1
(HGNC:4419)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
GNRHR
(HGNC:4421)
hypogonadotropic hypogonadism 7 with or without anosmia
(MONDO_0007794)
Definitive
GOSR2
(HGNC:4431)
progressive myoclonic epilepsy type 6
(MONDO_0013526)
Limited
GP1BA
(HGNC:4439)
autosomal dominant macrothrombocytopenia
(MONDO_0015372)
Strong
ALS2
(HGNC:443)
amyotrophic lateral sclerosis type 2, juvenile
(MONDO_0008780)
Strong
ALS2
(HGNC:443)
juvenile primary lateral sclerosis
(MONDO_0011663)
Definitive
ALS2
(HGNC:443)
infantile-onset ascending hereditary spastic paralysis
(MONDO_0011797)
Definitive
GP1BB
(HGNC:4440)
Bernard-Soulier syndrome
(MONDO_0009276)
Definitive
ALS2
(HGNC:443)
juvenile amyotrophic lateral sclerosis
(MONDO_0017593)
Strong
GPC6
(HGNC:4454)
autosomal recessive omodysplasia
(MONDO_0009779)
Strong
GPC4
(HGNC:4452)
Keipert syndrome
(MONDO_0009720)
Strong
GPAA1
(HGNC:4446)
glycosylphosphatidylinositol biosynthesis defect 15
(MONDO_0060627)
Moderate
SETX
(HGNC:445)
amyotrophic lateral sclerosis type 4
(MONDO_0011223)
Strong
SETX
(HGNC:445)
distal hereditary motor neuropathy
(MONDO_0018894)
Limited
ADGRG1
(HGNC:4512)
bilateral frontoparietal polymicrogyria
(MONDO_0011738)
Strong
GPR68
(HGNC:4519)
amelogenesis imperfecta type 2
(MONDO_0015048)
Limited
GRHPR
(HGNC:4570)
primary hyperoxaluria type 2
(MONDO_0009824)
Definitive
GRID2
(HGNC:4576)
autosomal recessive spinocerebellar ataxia 18
(MONDO_0014530)
Strong
GRIK2
(HGNC:4580)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Limited
ALX3
(HGNC:449)
frontorhiny
(MONDO_0007636)
Definitive
GABBR2
(HGNC:4507)
neurodevelopmental disorder with poor language and loss of hand skills
(MONDO_0060659)
Limited
ALX4
(HGNC:450)
parietal foramina 2
(MONDO_0012309)
Moderate
KISS1R
(HGNC:4510)
hypogonadotropic hypogonadism
(MONDO_0018555)
Strong
AMACR
(HGNC:451)
alpha-methylacyl-CoA racemase deficiency
(MONDO_0013681)
Definitive
GRIN2A
(HGNC:4585)
childhood epilepsy with centrotemporal spikes
(MONDO_0007295)
Strong
GRIN2A
(HGNC:4585)
Landau-Kleffner syndrome
(MONDO_0009509)
Moderate
GRIN2A
(HGNC:4585)
neurodevelopmental disorder
(MONDO_0700092)
Strong
GRIN2C
(HGNC:4587)
Alzheimer disease
(MONDO_0004975)
Moderate
GRIN2B
(HGNC:4586)
West syndrome
(MONDO_0018097)
Moderate
GRM1
(HGNC:4593)
spinocerebellar ataxia 44
(MONDO_0033479)
Limited
GRM1
(HGNC:4593)
autosomal recessive spinocerebellar ataxia 13
(MONDO_0013905)
Strong
ABCB4
(HGNC:45)
low phospholipid associated cholelithiasis
(MONDO_0010939)
Strong
ABCB4
(HGNC:45)
progressive familial intrahepatic cholestasis type 3
(MONDO_0011214)
Strong
GRM6
(HGNC:4598)
congenital stationary night blindness
(MONDO_0016293)
Definitive
GRN
(HGNC:4601)
GRN-related frontotemporal lobar degeneration with Tdp43 inclusions
(MONDO_0011842)
Definitive
GRN
(HGNC:4601)
neuronal ceroid lipofuscinosis 11
(MONDO_0013866)
Strong
GSK3B
(HGNC:4617)
neurodevelopmental disorder
(MONDO_0700092)
Strong
GRN
(HGNC:4601)
neuronal ceroid lipofuscinosis
(MONDO_0016295)
Definitive
GSS
(HGNC:4624)
glutathione synthetase deficiency with 5-oxoprolinuria
(MONDO_0009947)
Definitive
GSTM3
(HGNC:4635)
cystic fibrosis
(MONDO_0009061)
Limited
GSTZ1
(HGNC:4643)
maleylacetoacetate isomerase deficiency
(MONDO_0060527)
Disputed
AMHR2
(HGNC:465)
persistent Mullerian duct syndrome
(MONDO_0009857)
Strong
GUCA1A
(HGNC:4678)
cone dystrophy
(MONDO_0000455)
Definitive
GUCA1A
(HGNC:4678)
central areolar choroidal dystrophy
(MONDO_0008982)
Moderate
GUCA1B
(HGNC:4679)
retinitis pigmentosa
(MONDO_0019200)
Moderate
GUCA1A
(HGNC:4678)
cone-rod dystrophy
(MONDO_0015993)
Definitive
GUCY2C
(HGNC:4688)
congenital sodium diarrhea
(MONDO_0015170)
Moderate
AMMECR1
(HGNC:467)
Alport syndrome-intellectual disability-midface hypoplasia-elliptocytosis syndrome
(MONDO_0010263)
Strong
GUCY2D
(HGNC:4689)
Leber congenital amaurosis 1
(MONDO_0008764)
Definitive
GUCY2D
(HGNC:4689)
central areolar choroidal dystrophy
(MONDO_0008982)
Limited
GUCY2D
(HGNC:4689)
cone-rod dystrophy 6
(MONDO_0011143)
Moderate
GUCY2D
(HGNC:4689)
cone-rod dystrophy
(MONDO_0015993)
Strong
GYG1
(HGNC:4699)
glycogen storage disease XV
(MONDO_0013291)
Strong
AMPD1
(HGNC:468)
adenosine monophosphate deaminase deficiency
(MONDO_0013028)
Strong
GYG1
(HGNC:4699)
polyglucosan body myopathy type 2
(MONDO_0014526)
Strong
AMPD2
(HGNC:469)
pontocerebellar hypoplasia type 9
(MONDO_0014351)
Strong
GYS1
(HGNC:4706)
glycogen storage disease due to muscle and heart glycogen synthase deficiency
(MONDO_0012693)
Moderate
GYS2
(HGNC:4707)
glycogen storage disorder due to hepatic glycogen synthase deficiency
(MONDO_0009414)
Moderate
H1-4
(HGNC:4718)
Rahman syndrome
(MONDO_0044323)
Strong
AMT
(HGNC:473)
glycine encephalopathy
(MONDO_0011612)
Definitive
MACROH2A1
(HGNC:4740)
brachydactyly-elbow wrist dysplasia syndrome
(MONDO_0008520)
Limited
H6PD
(HGNC:4795)
cortisone reductase deficiency
(MONDO_0000193)
Strong
H6PD
(HGNC:4795)
cortisone reductase deficiency 1
(MONDO_0011503)
Strong
HAAO
(HGNC:4796)
congenital vertebral-cardiac-renal anomalies syndrome
(MONDO_0020831)
Strong
HADH
(HGNC:4799)
3-hydroxyacyl-CoA dehydrogenase deficiency
(MONDO_0017715)
Limited
ABCB6
(HGNC:47)
dyschromatosis universalis hereditaria
(MONDO_0000736)
Definitive
ABCB6
(HGNC:47)
familial pseudohyperkalemia
(MONDO_0012204)
Strong
HSD17B10
(HGNC:4800)
HSD10 mitochondrial disease
(MONDO_0010327)
Definitive
HADHA
(HGNC:4801)
long chain 3-hydroxyacyl-CoA dehydrogenase deficiency
(MONDO_0012173)
Strong
HAL
(HGNC:4806)
histidinemia
(MONDO_0009345)
Strong
HAND1
(HGNC:4807)
congenital heart disease
(MONDO_0005453)
Limited
HBA1
(HGNC:4823)
alpha thalassemia spectrum
(MONDO_0011399)
Definitive
HBA1
(HGNC:4823)
hemoglobin H disease
(MONDO_0013512)
Limited
HBA1
(HGNC:4823)
Hb Bart's hydrops fetalis
(MONDO_0015579)
Limited
HBA2
(HGNC:4824)
alpha thalassemia spectrum
(MONDO_0011399)
Definitive
HBA2
(HGNC:4824)
hemoglobin H disease
(MONDO_0013512)
Moderate
HBA2
(HGNC:4824)
hemoglobin M disease
(MONDO_0018023)
Limited
HBA2
(HGNC:4824)
Hb Bart's hydrops fetalis
(MONDO_0015579)
Definitive
HBB
(HGNC:4827)
dominant beta-thalassemia
(MONDO_0011381)
Moderate
HBB
(HGNC:4827)
hemoglobin E disease
(MONDO_0016243)
Limited
HBB
(HGNC:4827)
sickle cell anemia
(MONDO_0011382)
Definitive
HBB
(HGNC:4827)
beta-thalassemia major
(MONDO_0016486)
Definitive
HBB
(HGNC:4827)
beta-thalassemia intermedia
(MONDO_0016487)
Definitive
HBB
(HGNC:4827)
delta-beta-thalassemia
(MONDO_0016489)
Moderate
HBB
(HGNC:4827)
hemoglobin E-beta-thalassemia syndrome
(MONDO_0016491)
Moderate
HBB
(HGNC:4827)
sickle cell-hemoglobin E disease syndrome
(MONDO_0016671)
Moderate
HBB
(HGNC:4827)
sickle cell-hemoglobin c disease syndrome
(MONDO_0016669)
Moderate
HBB
(HGNC:4827)
hemoglobin M disease
(MONDO_0018023)
Limited
HBB
(HGNC:4827)
hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome
(MONDO_0018749)
Moderate
HBB
(HGNC:4827)
beta thalassemia
(MONDO_0019402)
Definitive
HBD
(HGNC:4829)
delta-beta-thalassemia
(MONDO_0016489)
Limited
HCFC1
(HGNC:4839)
X-linked intellectual disability
(MONDO_0100284)
Strong
HCN1
(HGNC:4845)
generalized epilepsy with febrile seizures plus
(MONDO_0018214)
Strong
ANG
(HGNC:483)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
ANGPT1
(HGNC:484)
primary congenital glaucoma
(MONDO_0000365)
Moderate
HTT
(HGNC:4851)
Lopes-Maciel-Rodan syndrome
(MONDO_0054573)
Limited
HFE
(HGNC:4886)
hemochromatosis type 1
(MONDO_0021001)
Definitive
ABCB7
(HGNC:48)
X-linked sideroblastic anemia with ataxia
(MONDO_0010524)
Strong
HESX1
(HGNC:4877)
septooptic dysplasia
(MONDO_0008428)
Strong
HIBADH
(HGNC:4907)
3-hydroxyisobutyric aciduria
(MONDO_0009371)
Moderate
HDC
(HGNC:4855)
Tourette syndrome
(MONDO_0007661)
Limited
HESX1
(HGNC:4877)
Kallmann syndrome
(MONDO_0018800)
Limited
HESX1
(HGNC:4877)
pituitary stalk interruption syndrome
(MONDO_0019828)
Limited
HIBCH
(HGNC:4908)
Leigh syndrome
(MONDO_0009723)
Strong
CFH
(HGNC:4883)
dense deposit disease
(MONDO_0019736)
Limited
CFH
(HGNC:4883)
basal laminar drusen
(MONDO_0007472)
Strong
HFE
(HGNC:4886)
cystic fibrosis
(MONDO_0009061)
Limited
HINT1
(HGNC:4912)
Gamstorp-Wohlfart syndrome
(MONDO_0007646)
Strong
HINT1
(HGNC:4912)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Definitive
HIRA
(HGNC:4916)
neurodevelopmental disorder
(MONDO_0700092)
Limited
ANGPTL3
(HGNC:491)
familial hypobetalipoproteinemia 2
(MONDO_0011505)
Moderate
HK1
(HGNC:4922)
Charcot-Marie-Tooth disease type 4G
(MONDO_0011534)
Strong
HK1
(HGNC:4922)
neurodevelopmental disorder with visual defects and brain anomalies
(MONDO_0032807)
Moderate
SLC39A7
(HGNC:4927)
agammaglobulinemia
(MONDO_0015977)
Strong
ANK2
(HGNC:493)
long QT syndrome
(MONDO_0002442)
Limited
ANK1
(HGNC:492)
hereditary spherocytosis type 1
(MONDO_0008447)
Definitive
ANK2
(HGNC:493)
cardiac arrhythmia, ankyrin-B-related
(MONDO_0010958)
Strong
ANK2
(HGNC:493)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Disputed
ANK2
(HGNC:493)
Brugada syndrome
(MONDO_0015263)
Limited
ANK2
(HGNC:493)
neurodevelopmental disorder
(MONDO_0700092)
Strong
ANK3
(HGNC:494)
intellectual disability
(MONDO_0001071)
Moderate
HLA-DRB1
(HGNC:4948)
systemic lupus erythematosus
(MONDO_0007915)
Definitive
RIPK4
(HGNC:496)
ectodermal dysplasia syndrome
(MONDO_0019287)
Moderate
MNX1
(HGNC:4979)
neonatal diabetes mellitus
(MONDO_0016391)
Limited
MNX1
(HGNC:4979)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Limited
HMGA2
(HGNC:5009)
Silver-Russell syndrome 5
(MONDO_0020795)
Strong
HMGCS2
(HGNC:5008)
3-hydroxy-3-methylglutaryl-CoA synthase deficiency
(MONDO_0011614)
Definitive
HMGA1
(HGNC:5010)
type 2 diabetes mellitus
(MONDO_0005148)
Moderate
HMOX1
(HGNC:5013)
chronic obstructive pulmonary disease
(MONDO_0005002)
Limited
HMOX1
(HGNC:5013)
heme oxygenase 1 deficiency
(MONDO_0013536)
Limited
HMX1
(HGNC:5017)
oculoauricular syndrome
(MONDO_0012802)
Moderate
HNF4A
(HGNC:5024)
maturity-onset diabetes of the young type 1
(MONDO_0007452)
Strong
HNF4A
(HGNC:5024)
monogenic diabetes
(MONDO_0015967)
Definitive
HNF4A
(HGNC:5024)
maturity-onset diabetes of the young
(MONDO_0018911)
Strong
HNMT
(HGNC:5028)
intellectual disability, autosomal recessive 51
(MONDO_0014759)
Strong
HNRNPA1
(HGNC:5031)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
HNRNPA2B1
(HGNC:5033)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
HNRNPH1
(HGNC:5041)
neurodevelopmental disorder
(MONDO_0700092)
Limited
HNRNPH2
(HGNC:5042)
intellectual disability, X-linked, syndromic, Bain type
(MONDO_0010512)
Strong
HOXA1
(HGNC:5099)
human HOXA1 syndromes
(MONDO_0011099)
Strong
HOXA1
(HGNC:5099)
Bosley-Salih-Alorainy syndrome
(MONDO_0019075)
Strong
HOXA2
(HGNC:5103)
microtia
(MONDO_0010920)
Strong
HOXB13
(HGNC:5112)
prostate cancer
(MONDO_0008315)
Definitive
HOXD13
(HGNC:5136)
synpolydactyly type 1
(MONDO_0008513)
Definitive
HOXD10
(HGNC:5133)
congenital vertical talus
(MONDO_0008652)
Strong
HOXD13
(HGNC:5136)
brachydactyly type E
(MONDO_0019677)
Moderate
HPCA
(HGNC:5144)
torsion dystonia 2
(MONDO_0009141)
Strong
HPGD
(HGNC:5154)
cranio-osteoarthropathy
(MONDO_0015466)
Moderate
HPGD
(HGNC:5154)
isolated congenital digital clubbing
(MONDO_0007343)
Limited
HR
(HGNC:5172)
alopecia universalis congenita
(MONDO_0008757)
Limited
HPGD
(HGNC:5154)
hypertrophic osteoarthropathy, primary, autosomal recessive, 1
(MONDO_0024546)
Strong
HR
(HGNC:5172)
Marie Unna hereditary hypotrichosis
(MONDO_0018631)
Definitive
HR
(HGNC:5172)
hypotrichosis 4
(MONDO_0100522)
Limited
HRAS
(HGNC:5173)
rhabdomyosarcoma
(MONDO_0005212)
Moderate
HRAS
(HGNC:5173)
Noonan syndrome-like disorder with loose anagen hair
(MONDO_0011899)
Limited
HRAS
(HGNC:5173)
Costello syndrome
(MONDO_0009026)
Definitive
ABCC1
(HGNC:51)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Limited
HS6ST1
(HGNC:5201)
hypogonadotropic hypogonadism
(MONDO_0018555)
Moderate
HS6ST1
(HGNC:5201)
Kallmann syndrome
(MONDO_0018800)
Moderate
HSD11B1
(HGNC:5208)
cortisone reductase deficiency
(MONDO_0000193)
Moderate
HSD17B3
(HGNC:5212)
46,XY disorder of sex development due to 17-beta-hydroxysteroid dehydrogenase 3 deficiency
(MONDO_0009916)
Definitive
HSD3B2
(HGNC:5218)
congenital adrenal hyperplasia due to 3-beta-hydroxysteroid dehydrogenase deficiency
(MONDO_0008727)
Definitive
HSF4
(HGNC:5227)
cataract 5 multiple types
(MONDO_0007290)
Strong
HSPA9
(HGNC:5244)
autosomal recessive sideroblastic anemia
(MONDO_0016828)
Limited
HSPB1
(HGNC:5246)
distal hereditary motor neuropathy type 2
(MONDO_0015352)
Strong
IARS1
(HGNC:5330)
growth retardation, intellectual developmental disorder, hypotonia, and hepatopathy
(MONDO_0014911)
Limited
HSPG2
(HGNC:5273)
Silverman-Handmaker type dyssegmental dysplasia
(MONDO_0009140)
Moderate
HSPG2
(HGNC:5273)
Schwartz-Jampel syndrome type 1
(MONDO_0100435)
Definitive
NOD2
(HGNC:5331)
Blau syndrome
(MONDO_0008523)
Definitive
ICOS
(HGNC:5351)
common variable immunodeficiency
(MONDO_0015517)
Definitive
ID2
(HGNC:5361)
congenital heart disease
(MONDO_0005453)
Limited
ANXA11
(HGNC:535)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
IDH1
(HGNC:5382)
Maffucci syndrome
(MONDO_0013808)
Definitive
IDH2
(HGNC:5383)
D-2-hydroxyglutaric aciduria
(MONDO_0010924)
Strong
IDH3B
(HGNC:5385)
retinitis pigmentosa
(MONDO_0019200)
Moderate
IDH3G
(HGNC:5386)
retinitis pigmentosa
(MONDO_0019200)
Strong
IDUA
(HGNC:5391)
Scheie syndrome
(MONDO_0011760)
Strong
IDUA
(HGNC:5391)
Hurler-Scheie syndrome
(MONDO_0011759)
Definitive
IFNAR1
(HGNC:5432)
immunodeficiency 106, susceptibility to viral infections
(MONDO_0030970)
Strong
ABCC2
(HGNC:53)
Dubin-Johnson syndrome
(MONDO_0009380)
Strong
IFRD1
(HGNC:5456)
spinocerebellar ataxia type 18
(MONDO_0011834)
Limited
IGF1
(HGNC:5464)
growth delay due to insulin-like growth factor type 1 deficiency
(MONDO_0012110)
Moderate
IGF1R
(HGNC:5465)
growth delay due to insulin-like growth factor I resistance
(MONDO_0010038)
Strong
IGFALS
(HGNC:5468)
short stature due to primary acid-labile subunit deficiency
(MONDO_0014420)
Moderate
IGFBP7
(HGNC:5476)
familial retinal arterial macroaneurysm
(MONDO_0013640)
Limited
IGHMBP2
(HGNC:5542)
Charcot-Marie-Tooth disease axonal type 2S
(MONDO_0014511)
Strong
AP1B1
(HGNC:554)
ichthyosiform erythroderma, corneal involvement, and hearing loss
(MONDO_0009440)
Moderate
AP1B1
(HGNC:554)
MEDNIK syndrome
(MONDO_0012251)
Strong
AP1S2
(HGNC:560)
autism spectrum disorder
(MONDO_0005258)
Limited
AP1S2
(HGNC:560)
syndromic X-linked intellectual disability 5
(MONDO_0010574)
Strong
AP1S2
(HGNC:560)
fried syndrome
(MONDO_0019428)
Strong
AP2S1
(HGNC:565)
familial hypocalciuric hypercalcemia 3
(MONDO_0010926)
Definitive
RBPJ
(HGNC:5724)
Adams-Oliver syndrome
(MONDO_0007034)
Moderate
AP4E1
(HGNC:573)
hereditary spastic paraplegia 51
(MONDO_0013401)
Limited
AP4B1
(HGNC:572)
hereditary spastic paraplegia 47
(MONDO_0013551)
Strong
AP4M1
(HGNC:574)
hereditary spastic paraplegia 50
(MONDO_0013048)
Strong
AP4S1
(HGNC:575)
hereditary spastic paraplegia 52
(MONDO_0013552)
Strong
ABCC6
(HGNC:57)
arterial calcification, generalized, of infancy, 2
(MONDO_0013768)
Limited
APC
(HGNC:583)
sarcoma
(MONDO_0005089)
Limited
APC
(HGNC:583)
desmoid tumor
(MONDO_0007608)
Strong
APC
(HGNC:583)
Cenani-Lenz syndactyly syndrome
(MONDO_0008931)
Limited
APEX1
(HGNC:587)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
ATG12
(HGNC:588)
colorectal cancer
(MONDO_0005575)
Limited
APC
(HGNC:583)
gastric adenocarcinoma and proximal polyposis of the stomach
(MONDO_0017790)
Strong
IGSF1
(HGNC:5948)
X-linked central congenital hypothyroidism with late-onset testicular enlargement
(MONDO_0010475)
Definitive
CADM1
(HGNC:5951)
autism spectrum disorder
(MONDO_0005258)
Limited
IHH
(HGNC:5956)
brachydactyly type A1
(MONDO_0007215)
Definitive
IHH
(HGNC:5956)
acrocapitofemoral dysplasia
(MONDO_0011907)
Strong
ELP1
(HGNC:5959)
Riley-Day syndrome
(MONDO_0009131)
Definitive
IKBKG
(HGNC:5961)
ectodermal dysplasia and immune deficiency
(MONDO_0010293)
Definitive
IL10
(HGNC:5962)
systemic lupus erythematosus
(MONDO_0007915)
Moderate
IL12RB1
(HGNC:5971)
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency
(MONDO_0013955)
Definitive
IL11RA
(HGNC:5967)
craniosynostosis and dental anomalies
(MONDO_0013615)
Definitive
ABCC8
(HGNC:59)
diabetes mellitus
(MONDO_0005015)
Strong
IL17RA
(HGNC:5985)
chronic mucocutaneous candidiasis
(MONDO_0015279)
Definitive
ABCC8
(HGNC:59)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
ABCC8
(HGNC:59)
pulmonary arterial hypertension
(MONDO_0015924)
Moderate
ABCC8
(HGNC:59)
monogenic diabetes
(MONDO_0015967)
Strong
ABCC8
(HGNC:59)
maturity-onset diabetes of the young
(MONDO_0018911)
Definitive
ABCC8
(HGNC:59)
transient neonatal diabetes mellitus
(MONDO_0020525)
Definitive
ABCC8
(HGNC:59)
familial hyperinsulinism
(MONDO_0017182)
Definitive
IL1RN
(HGNC:6000)
sterile multifocal osteomyelitis with periostitis and pustulosis
(MONDO_0013021)
Strong
ABCC8
(HGNC:59)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Definitive
IL2RA
(HGNC:6008)
immunodeficiency due to CD25 deficiency
(MONDO_0011664)
Limited
IL21
(HGNC:6005)
common variable immunodeficiency
(MONDO_0015517)
Limited
APOA1
(HGNC:600)
hypoalphalipoproteinemia, primary, 2
(MONDO_0032766)
Limited
IL2RA
(HGNC:6008)
neonatal diabetes mellitus
(MONDO_0016391)
Limited
IL7R
(HGNC:6024)
Omenn syndrome
(MONDO_0011338)
Limited
APOB
(HGNC:603)
hypercholesterolemia, autosomal dominant, type B
(MONDO_0007751)
Definitive
IL2RG
(HGNC:6010)
Omenn syndrome
(MONDO_0011338)
Limited
APOB
(HGNC:603)
homozygous familial hypercholesterolemia
(MONDO_0018328)
Limited
IMPDH1
(HGNC:6052)
Leber congenital amaurosis 11
(MONDO_0013454)
Limited
IMPDH1
(HGNC:6052)
Leber congenital amaurosis
(MONDO_0018998)
Limited
IMPDH1
(HGNC:6052)
inherited retinal dystrophy
(MONDO_0019118)
Strong
APOA1
(HGNC:600)
AApoAI amyloidosis
(MONDO_0019731)
Limited
IMPDH1
(HGNC:6052)
retinitis pigmentosa
(MONDO_0019200)
Strong
IMPG1
(HGNC:6055)
retinitis pigmentosa
(MONDO_0019200)
Strong
IMPG1
(HGNC:6055)
adult-onset foveomacular vitelliform dystrophy
(MONDO_0011979)
Strong
ING1
(HGNC:6062)
head and neck squamous cell carcinoma
(MONDO_0010150)
Limited
INS
(HGNC:6081)
maturity-onset diabetes of the young type 10
(MONDO_0013240)
Moderate
INPPL1
(HGNC:6080)
opsismodysplasia
(MONDO_0009785)
Strong
INS
(HGNC:6081)
hyperproinsulinemia
(MONDO_0014535)
Limited
INS
(HGNC:6081)
maturity-onset diabetes of the young
(MONDO_0018911)
Strong
INS
(HGNC:6081)
transient neonatal diabetes mellitus
(MONDO_0020525)
Limited
INS
(HGNC:6081)
monogenic diabetes
(MONDO_0015967)
Definitive
INSL3
(HGNC:6086)
cryptorchidism
(MONDO_0009047)
Moderate
INS
(HGNC:6081)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Definitive
INSR
(HGNC:6091)
Rabson-Mendenhall syndrome
(MONDO_0009874)
Definitive
INSR
(HGNC:6091)
Donohue syndrome
(MONDO_0009517)
Strong
INSR
(HGNC:6091)
insulin-resistance syndrome type A
(MONDO_0012520)
Strong
APOC2
(HGNC:609)
familial apolipoprotein C-II deficiency
(MONDO_0008810)
Moderate
ABCC9
(HGNC:60)
dilated cardiomyopathy
(MONDO_0005021)
Limited
ABCC9
(HGNC:60)
Brugada syndrome
(MONDO_0015263)
Moderate
FOXP3
(HGNC:6106)
immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome
(MONDO_0010580)
Definitive
PDX1
(HGNC:6107)
pancreatic agenesis
(MONDO_0009832)
Definitive
PDX1
(HGNC:6107)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Limited
PDX1
(HGNC:6107)
maturity-onset diabetes of the young
(MONDO_0018911)
Limited
IRAK1
(HGNC:6112)
systemic lupus erythematosus
(MONDO_0007915)
Strong
IRF5
(HGNC:6120)
systemic lupus erythematosus
(MONDO_0007915)
Definitive
IRF6
(HGNC:6121)
tooth agenesis
(MONDO_0005486)
Disputed
IRF6
(HGNC:6121)
van der Woude syndrome 1
(MONDO_0007333)
Definitive
IRX4
(HGNC:6129)
congenital heart disease
(MONDO_0005453)
Limited
ITGA3
(HGNC:6139)
epidermolysis bullosa, junctional 7, with interstitial lung disease and nephrotic syndrome
(MONDO_0013881)
Strong
APOE
(HGNC:613)
lipoprotein glomerulopathy
(MONDO_0012725)
Strong
APOE
(HGNC:613)
hyperlipoproteinemia type 3
(MONDO_0018473)
Definitive
ITGA7
(HGNC:6143)
congenital fiber-type disproportion myopathy
(MONDO_0009711)
Limited
ITGA8
(HGNC:6144)
bilateral renal agenesis
(MONDO_0015986)
Strong
ITGAM
(HGNC:6149)
systemic lupus erythematosus
(MONDO_0007915)
Strong
ITGB3
(HGNC:6156)
Glanzmann thrombasthenia
(MONDO_0100326)
Definitive
ITGB4
(HGNC:6158)
aplasia cutis congenita
(MONDO_0007145)
Limited
ITGB4
(HGNC:6158)
junctional epidermolysis bullosa with pyloric atresia
(MONDO_0009183)
Definitive
ITK
(HGNC:6171)
lymphoproliferative syndrome 1
(MONDO_0013081)
Strong
ITK
(HGNC:6171)
lymphoproliferative syndrome
(MONDO_0016537)
Definitive
ITM2B
(HGNC:6174)
ADan amyloidosis
(MONDO_0007297)
Limited
ITGB4
(HGNC:6158)
epidermolysis bullosa simplex
(MONDO_0017610)
Limited
EIF6
(HGNC:6159)
Shwachman-Diamond syndrome
(MONDO_0009833)
Limited
STT3A
(HGNC:6172)
STT3A-congenital disorder of glycosylation
(MONDO_0014270)
Strong
ITPA
(HGNC:6176)
developmental and epileptic encephalopathy, 35
(MONDO_0014719)
Strong
ITM2B
(HGNC:6174)
ABri amyloidosis
(MONDO_0008306)
Limited
ITPR1
(HGNC:6180)
spinocerebellar ataxia type 15/16
(MONDO_0011694)
Definitive
ITPA
(HGNC:6176)
inosine triphosphatase deficiency
(MONDO_0013461)
Strong
ITPR1
(HGNC:6180)
spinocerebellar ataxia type 29
(MONDO_0007298)
Strong
ITPR1
(HGNC:6180)
aniridia-cerebellar ataxia-intellectual disability syndrome
(MONDO_0008795)
Strong
JAK3
(HGNC:6193)
T-B+ severe combined immunodeficiency due to JAK3 deficiency
(MONDO_0010938)
Definitive
ABCD1
(HGNC:61)
adrenomyeloneuropathy
(MONDO_0015339)
Definitive
JAG1
(HGNC:6188)
tetralogy of fallot
(MONDO_0008542)
Limited
APOL2
(HGNC:619)
schizophrenia
(MONDO_0005090)
Limited
JAG1
(HGNC:6188)
Alagille syndrome due to a JAG1 point mutation
(MONDO_0016862)
Definitive
JAK2
(HGNC:6192)
familial thrombocytosis
(MONDO_0019111)
Moderate
ABCD1
(HGNC:61)
adrenoleukodystrophy
(MONDO_0018544)
Definitive
JUP
(HGNC:6207)
Naxos disease
(MONDO_0011017)
Definitive
ABCD1
(HGNC:61)
Hirschsprung disease
(MONDO_0018309)
Limited
ABCD1
(HGNC:61)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
KCNE5
(HGNC:6241)
Brugada syndrome
(MONDO_0015263)
Limited
KCNE3
(HGNC:6243)
Brugada syndrome
(MONDO_0015263)
Limited
KCND3
(HGNC:6239)
spinocerebellar ataxia type 19/22
(MONDO_0011819)
Definitive
KCNH2
(HGNC:6251)
short QT syndrome
(MONDO_0000453)
Definitive
KCNC1
(HGNC:6233)
progressive myoclonus epilepsy
(MONDO_0020074)
Definitive
KCNC2
(HGNC:6234)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
KCNE1
(HGNC:6240)
atrial fibrillation
(MONDO_0004981)
Limited
KCNE1
(HGNC:6240)
long QT syndrome 5
(MONDO_0013372)
Definitive
APP
(HGNC:620)
ABeta amyloidosis, dutch type
(MONDO_0015033)
Moderate
APP
(HGNC:620)
cerebral amyloid angiopathy, APP-related
(MONDO_0011583)
Limited
KCNA1
(HGNC:6218)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
KCNA2
(HGNC:6220)
developmental and epileptic encephalopathy
(MONDO_0100062)
Strong
KCNH2
(HGNC:6251)
long QT syndrome 2
(MONDO_0013367)
Definitive
KCNH2
(HGNC:6251)
long QT syndrome
(MONDO_0002442)
Definitive
KCNH2
(HGNC:6251)
Brugada syndrome
(MONDO_0015263)
Moderate
KCNE2
(HGNC:6242)
long QT syndrome
(MONDO_0002442)
Limited
KCNJ10
(HGNC:6256)
EAST syndrome
(MONDO_0013005)
Definitive
KCNC1
(HGNC:6233)
progressive myoclonic epilepsy type 7
(MONDO_0014521)
Strong
KCNJ10
(HGNC:6256)
Pendred syndrome
(MONDO_0010134)
Limited
KCNJ11
(HGNC:6257)
maturity-onset diabetes of the young type 13
(MONDO_0014589)
Strong
KCNJ11
(HGNC:6257)
monogenic diabetes
(MONDO_0015967)
Strong
KCNJ11
(HGNC:6257)
maturity-onset diabetes of the young
(MONDO_0018911)
Strong
KCNJ11
(HGNC:6257)
DEND syndrome
(MONDO_0019207)
Strong
KCNJ11
(HGNC:6257)
intermediate DEND syndrome
(MONDO_0020569)
Strong
KCNJ11
(HGNC:6257)
permanent neonatal diabetes mellitus
(MONDO_0100164)
Definitive
KCNJ11
(HGNC:6257)
transient neonatal diabetes mellitus
(MONDO_0020525)
Strong
KCNJ13
(HGNC:6259)
snowflake vitreoretinal degeneration
(MONDO_0008663)
Strong
KCNJ13
(HGNC:6259)
Leber congenital amaurosis
(MONDO_0018998)
Strong
KCNJ16
(HGNC:6262)
hypokalemic tubulopathy and deafness
(MONDO_0859167)
Strong
KCNJ2
(HGNC:6263)
Andersen-Tawil syndrome
(MONDO_0008222)
Definitive
KCNJ2
(HGNC:6263)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Disputed
KCNJ2
(HGNC:6263)
long QT syndrome
(MONDO_0002442)
Limited
KCNJ2
(HGNC:6263)
short QT syndrome type 3
(MONDO_0012314)
Limited
KCNJ2
(HGNC:6263)
short QT syndrome
(MONDO_0000453)
Moderate
KCNJ5
(HGNC:6266)
Andersen-Tawil syndrome
(MONDO_0008222)
Limited
KCNJ5
(HGNC:6266)
familial hyperaldosteronism type III
(MONDO_0013359)
Strong
KCNJ5
(HGNC:6266)
long QT syndrome
(MONDO_0002442)
Limited
KCNJ6
(HGNC:6267)
Keppen-Lubinsky syndrome
(MONDO_0013572)
Strong
KCNJ8
(HGNC:6269)
hypertrichotic osteochondrodysplasia Cantu type
(MONDO_0009406)
Limited
KCNJ5
(HGNC:6266)
long QT syndrome 13
(MONDO_0013279)
Limited
KCNJ8
(HGNC:6269)
Brugada syndrome
(MONDO_0015263)
Moderate
KCNK3
(HGNC:6278)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
KCNK3
(HGNC:6278)
heritable pulmonary arterial hypertension
(MONDO_0017148)
Moderate
KCNMA1
(HGNC:6284)
Liang-Wang syndrome
(MONDO_0032886)
Moderate
KCNK4
(HGNC:6279)
facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth syndrome
(MONDO_0032714)
Strong
KCNK9
(HGNC:6283)
Birk-Barel syndrome
(MONDO_0012856)
Strong
KCNN3
(HGNC:6292)
Zimmermann-Laband syndrome
(MONDO_0000200)
Strong
KCNN4
(HGNC:6293)
dehydrated hereditary stomatocytosis
(MONDO_0017910)
Strong
KCNQ1
(HGNC:6294)
Jervell and Lange-Nielsen syndrome
(MONDO_0002441)
Definitive
KCNQ1
(HGNC:6294)
short QT syndrome
(MONDO_0000453)
Strong
KCNQ1
(HGNC:6294)
long QT syndrome
(MONDO_0002442)
Definitive
KCNQ1
(HGNC:6294)
hypertrophic cardiomyopathy
(MONDO_0005045)
Limited
KCNQ1
(HGNC:6294)
familial atrial fibrillation
(MONDO_0018054)
Limited
KCNQ1
(HGNC:6294)
long QT syndrome 1
(MONDO_0100316)
Definitive
KCNQ2
(HGNC:6296)
seizures, benign familial neonatal, 2
(MONDO_0007366)
Strong
KCNQ2
(HGNC:6296)
developmental and epileptic encephalopathy, 7
(MONDO_0013387)
Strong
KCNQ2
(HGNC:6296)
malignant migrating partial seizures of infancy
(MONDO_0017385)
Limited
KCNQ2
(HGNC:6296)
benign neonatal seizures
(MONDO_0016027)
Definitive
KCNQ2
(HGNC:6296)
benign familial infantile epilepsy
(MONDO_0017615)
Moderate
KCNQ3
(HGNC:6297)
benign familial infantile epilepsy
(MONDO_0017615)
Limited
KCNQ3
(HGNC:6297)
seizures, benign familial neonatal, 2
(MONDO_0007366)
Strong
KCNQ4
(HGNC:6298)
hearing loss disorder
(MONDO_0005365)
Strong
KDR
(HGNC:6307)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
KCNQ4
(HGNC:6298)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Strong
KERA
(HGNC:6309)
cornea plana
(MONDO_0000733)
Definitive
KIF1C
(HGNC:6317)
spastic ataxia 2
(MONDO_0012651)
Moderate
KIF2A
(HGNC:6318)
complex cortical dysplasia with other brain malformations 3
(MONDO_0014170)
Limited
KIF3B
(HGNC:6320)
ciliopathy
(MONDO_0005308)
Strong
AQP1
(HGNC:633)
pulmonary arterial hypertension
(MONDO_0015924)
Limited
KISS1
(HGNC:6341)
hypogonadotropic hypogonadism
(MONDO_0018555)
Limited
KIT
(HGNC:6342)
mastocytosis
(MONDO_0007950)
Definitive
KIT
(HGNC:6342)
gastrointestinal stromal tumor
(MONDO_0011719)
Definitive
KIT
(HGNC:6342)
piebaldism
(MONDO_0008244)
Definitive
KIT
(HGNC:6342)
cutaneous mastocytosis
(MONDO_0019023)
Moderate
KITLG
(HGNC:6343)
hyperpigmentation with or without hypopigmentation, familial progressive
(MONDO_0007771)
Limited
KITLG
(HGNC:6343)
Waardenburg syndrome type 2
(MONDO_0019517)
Limited
KITLG
(HGNC:6343)
familial progressive hyper- and hypopigmentation
(MONDO_0017239)
Definitive
KLF1
(HGNC:6345)
congenital dyserythropoietic anemia type 4
(MONDO_0013355)
Strong
KLF1
(HGNC:6345)
hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome
(MONDO_0018749)
Strong
KLF2
(HGNC:6347)
pulmonary arterial hypertension
(MONDO_0015924)
Limited
KLHL3
(HGNC:6354)
pseudohypoaldosteronism type 2D
(MONDO_0013781)
Definitive
KLK1
(HGNC:6357)
pulmonary arterial hypertension
(MONDO_0015924)
Moderate
AQP4
(HGNC:637)
neuromyelitis optica
(MONDO_0019100)
Limited
KIF11
(HGNC:6388)
microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability
(MONDO_0007918)
Definitive
KNG1
(HGNC:6383)
congenital high-molecular-weight kininogen deficiency
(MONDO_0009234)
Definitive
KIF22
(HGNC:6391)
spondyloepimetaphyseal dysplasia with multiple dislocations
(MONDO_0011335)
Strong
KRAS
(HGNC:6407)
linear nevus sebaceous syndrome
(MONDO_0008097)
Strong
KRAS
(HGNC:6407)
Costello syndrome
(MONDO_0009026)
Limited
KRAS
(HGNC:6407)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Limited
KRAS
(HGNC:6407)
Noonan syndrome
(MONDO_0018997)
Definitive
KRT1
(HGNC:6412)
epidermolytic ichthyosis
(MONDO_0007239)
Strong
MAFB
(HGNC:6408)
Duane retraction syndrome
(MONDO_0007473)
Strong
KRT1
(HGNC:6412)
ichthyosis hystrix of Curth-Macklin
(MONDO_0007808)
Limited
KRT1
(HGNC:6412)
annular epidermolytic ichthyosis
(MONDO_0011870)
Moderate
KRT1
(HGNC:6412)
diffuse nonepidermolytic palmoplantar keratoderma
(MONDO_0010962)
Limited
KRT1
(HGNC:6412)
congenital reticular ichthyosiform erythroderma
(MONDO_0012208)
Limited
KRT1
(HGNC:6412)
striate palmoplantar keratoderma
(MONDO_0018865)
Moderate
KRT10
(HGNC:6413)
congenital reticular ichthyosiform erythroderma
(MONDO_0012208)
Limited
KRT10
(HGNC:6413)
annular epidermolytic ichthyosis
(MONDO_0011870)
Limited
KRT10
(HGNC:6413)
autosomal recessive epidermolytic ichthyosis
(MONDO_0044742)
Moderate
KRT14
(HGNC:6416)
dermatopathia pigmentosa reticularis
(MONDO_0007445)
Moderate
KRT14
(HGNC:6416)
epidermolysis bullosa simplex 2F, with mottled pigmentation
(MONDO_0007556)
Limited
KRT14
(HGNC:6416)
epidermolysis bullosa simplex 1A, generalized severe
(MONDO_0007550)
Strong
KRT14
(HGNC:6416)
Naegeli-Franceschetti-Jadassohn syndrome
(MONDO_0008059)
Definitive
KRT16
(HGNC:6423)
pachyonychia congenita 1
(MONDO_0008173)
Strong
KRT17
(HGNC:6427)
pachyonychia congenita 2
(MONDO_0008174)
Strong
KRT17
(HGNC:6427)
sebocystomatosis
(MONDO_0008485)
Strong
KRT18
(HGNC:6430)
cirrhosis, familial
(MONDO_0007329)
Limited
KRT3
(HGNC:6440)
Meesmann corneal dystrophy
(MONDO_0007379)
Strong
KRT5
(HGNC:6442)
epidermolysis bullosa simplex 2F, with mottled pigmentation
(MONDO_0007556)
Strong
KRT5
(HGNC:6442)
Dowling-Degos disease
(MONDO_0008371)
Strong
KRT5
(HGNC:6442)
epidermolysis bullosa simplex 2E, with migratory circinate erythema
(MONDO_0012258)
Limited
AR
(HGNC:644)
partial androgen insensitivity syndrome
(MONDO_0010720)
Definitive
AR
(HGNC:644)
Kennedy disease
(MONDO_0010735)
Definitive
AR
(HGNC:644)
androgen insensitivity syndrome
(MONDO_0019154)
Definitive
KRT81
(HGNC:6458)
monilethrix
(MONDO_0008009)
Limited
AR
(HGNC:644)
complete androgen insensitivity syndrome
(MONDO_0021023)
Definitive
KRT83
(HGNC:6460)
erythrokeratodermia variabilis
(MONDO_0017851)
Limited
KYNU GENE
(HGNC:6469)
congenital vertebral-cardiac-renal anomalies syndrome
(MONDO_0020831)
Strong
L1CAM
(HGNC:6470)
MASA syndrome
(MONDO_0010559)
Definitive
L1CAM
(HGNC:6470)
X-linked hydrocephalus with stenosis of the aqueduct of Sylvius
(MONDO_0010611)
Definitive
AFF3
(HGNC:6473)
intellectual disability
(MONDO_0001071)
Limited
L1CAM
(HGNC:6470)
L1 syndrome
(MONDO_0017140)
Definitive
AFF3
(HGNC:6473)
KINSSHIP syndrome
(MONDO_0851095)
Definitive
LAMA2
(HGNC:6482)
congenital merosin-deficient muscular dystrophy 1A
(MONDO_0011925)
Definitive
LAMA2
(HGNC:6482)
muscular dystrophy, limb-girdle, autosomal recessive 23
(MONDO_0029136)
Strong
LAMA3
(HGNC:6483)
junctional epidermolysis bullosa Herlitz type
(MONDO_0009182)
Strong
LAMA3
(HGNC:6483)
laryngo-onycho-cutaneous syndrome
(MONDO_0009513)
Definitive
LAMA2
(HGNC:6482)
LAMA2-related muscular dystrophy
(MONDO_0100228)
Definitive
LAMA4
(HGNC:6484)
dilated cardiomyopathy
(MONDO_0005021)
Limited
LAMB3
(HGNC:6490)
junctional epidermolysis bullosa Herlitz type
(MONDO_0009182)
Definitive
LAMB3
(HGNC:6490)
generalized junctional epidermolysis bullosa non-Herlitz type
(MONDO_0019307)
Strong
LAMC2
(HGNC:6493)
junctional epidermolysis bullosa
(MONDO_0017612)
Definitive
LARGE1
(HGNC:6511)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Limited
LBR
(HGNC:6518)
Greenberg dysplasia
(MONDO_0008974)
Strong
LBR
(HGNC:6518)
Pelger-Huet anomaly
(MONDO_0008214)
Definitive
LCAT
(HGNC:6522)
fish eye disease
(MONDO_0007620)
Definitive
LBR
(HGNC:6518)
regressive spondylometaphyseal dysplasia
(MONDO_0018663)
Moderate
LCAT
(HGNC:6522)
Norum disease
(MONDO_0009515)
Definitive
LCAT
(HGNC:6522)
LCAT deficiency
(MONDO_0018999)
Definitive
LCT
(HGNC:6530)
congenital lactase deficiency
(MONDO_0009115)
Definitive
LDLR
(HGNC:6547)
hypercholesterolemia, familial, 1
(MONDO_0007750)
Definitive
LDLR
(HGNC:6547)
homozygous familial hypercholesterolemia
(MONDO_0018328)
Definitive
ARF3
(HGNC:654)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
LEP
(HGNC:6553)
obesity due to congenital leptin deficiency
(MONDO_0013991)
Definitive
LEPR
(HGNC:6554)
obesity due to leptin receptor gene deficiency
(MONDO_0013992)
Strong
LHB
(HGNC:6584)
hypogonadotropic hypogonadism 23 with or without anosmia
(MONDO_0009223)
Limited
LIG4
(HGNC:6601)
Dubowitz syndrome
(MONDO_0009124)
Moderate
LHCGR
(HGNC:6585)
familial male-limited precocious puberty
(MONDO_0008303)
Strong
LIPC
(HGNC:6619)
hyperlipidemia due to hepatic triglyceride lipase deficiency
(MONDO_0013533)
Strong
LIG4
(HGNC:6601)
DNA ligase IV deficiency
(MONDO_0011686)
Strong
LIPE
(HGNC:6621)
LIPE-related familial partial lipodystrophy
(MONDO_0014431)
Limited
LMAN1
(HGNC:6631)
combined deficiency of factor V and factor VIII
(MONDO_0018175)
Definitive
LMNA
(HGNC:6636)
atrioventricular block
(MONDO_0000465)
Definitive
LMNA
(HGNC:6636)
atrial fibrillation
(MONDO_0004981)
Moderate
LMNA
(HGNC:6636)
dilated cardiomyopathy
(MONDO_0005021)
Definitive
LMNA
(HGNC:6636)
dilated cardiomyopathy 1A
(MONDO_0007269)
Definitive
LMNA
(HGNC:6636)
dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome
(MONDO_0008915)
Limited
LMNA
(HGNC:6636)
familial partial lipodystrophy, Dunnigan type
(MONDO_0007906)
Definitive
LMNA
(HGNC:6636)
Hutchinson-Gilford progeria syndrome
(MONDO_0008310)
Definitive
LMNA
(HGNC:6636)
Charcot-Marie-Tooth disease type 2B1
(MONDO_0011569)
Definitive
LMNA
(HGNC:6636)
mandibuloacral dysplasia with type A lipodystrophy
(MONDO_0009557)
Moderate
LMNA
(HGNC:6636)
congenital muscular dystrophy due to LMNA mutation
(MONDO_0013178)
Strong
LMNA
(HGNC:6636)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Moderate
LMNA
(HGNC:6636)
atypical Werner syndrome
(MONDO_0019321)
Strong
LMNA
(HGNC:6636)
Emery-Dreifuss muscular dystrophy 2, autosomal dominant
(MONDO_0021569)
Strong
LMOD3
(HGNC:6649)
nemaline myopathy 10
(MONDO_0014513)
Strong
LMX1A
(HGNC:6653)
Mobius syndrome
(MONDO_0008006)
Limited
LMNB1
(HGNC:6637)
adult-onset autosomal dominant demyelinating leukodystrophy
(MONDO_0008215)
Definitive
LMX1B
(HGNC:6654)
nail-patella syndrome
(MONDO_0008061)
Definitive
LMX1B
(HGNC:6654)
nail-patella-like renal disease
(MONDO_0009724)
Moderate
LORICRIN
(HGNC:6663)
loricrin keratoderma
(MONDO_0011396)
Strong
LPL
(HGNC:6677)
hyperlipidemia, familial combined, LPL related
(MONDO_0007759)
Limited
LRAT
(HGNC:6685)
severe early-childhood-onset retinal dystrophy
(MONDO_0009549)
Limited
RHOA
(HGNC:667)
ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies
(MONDO_0032884)
Limited
LRAT
(HGNC:6685)
Leber congenital amaurosis
(MONDO_0018998)
Moderate
LRAT
(HGNC:6685)
retinitis pigmentosa
(MONDO_0019200)
Moderate
LRP1
(HGNC:6692)
schizophrenia
(MONDO_0005090)
Moderate
LRP2
(HGNC:6694)
Stickler syndrome
(MONDO_0019354)
Limited
LRP4
(HGNC:6696)
sclerosteosis 2
(MONDO_0013679)
Moderate
LRP4
(HGNC:6696)
congenital myasthenic syndrome 17
(MONDO_0014578)
Strong
LRP4
(HGNC:6696)
sclerosteosis
(MONDO_0017838)
Strong
LRP5
(HGNC:6697)
autosomal dominant osteosclerosis, Worth type
(MONDO_0007764)
Definitive
LRP5
(HGNC:6697)
hyperostosis corticalis generalisata
(MONDO_0009395)
Strong
LRP5
(HGNC:6697)
osteoporosis-pseudoglioma syndrome
(MONDO_0009820)
Definitive
LRP5
(HGNC:6697)
exudative vitreoretinopathy
(MONDO_0019516)
Definitive
LRP6
(HGNC:6698)
tooth agenesis
(MONDO_0005486)
Strong
LRRFIP1
(HGNC:6702)
schizophrenia
(MONDO_0005090)
Limited
LSS
(HGNC:6708)
hypotrichosis simplex
(MONDO_0018914)
Moderate
LSS
(HGNC:6708)
cataract 44
(MONDO_0014673)
Definitive
LSS
(HGNC:6708)
alopecia-intellectual disability syndrome 4
(MONDO_0030009)
Strong
LSS
(HGNC:6708)
hypotrichosis 14
(MONDO_0032649)
Moderate
LTBP2
(HGNC:6715)
congenital glaucoma
(MONDO_0020366)
Limited
LTBP2
(HGNC:6715)
Weill-Marchesani syndrome
(MONDO_0018096)
Moderate
LYZ
(HGNC:6740)
ALys amyloidosis
(MONDO_0019732)
Strong
LZTFL1
(HGNC:6741)
ciliopathy
(MONDO_0005308)
Moderate
LZTFL1
(HGNC:6741)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
LZTR1
(HGNC:6742)
breast cancer
(MONDO_0007254)
Limited
CAPRIN1
(HGNC:6743)
autism spectrum disorder
(MONDO_0005258)
Limited
ARHGAP4
(HGNC:674)
intellectual disability
(MONDO_0001071)
Limited
MAD2L2
(HGNC:6764)
Fanconi anemia
(MONDO_0019391)
Strong
SMAD2
(HGNC:6768)
congenital heart disease
(MONDO_0005453)
Limited
SMAD2
(HGNC:6768)
Loeys-Dietz syndrome
(MONDO_0018954)
Limited
SMAD3
(HGNC:6769)
aneurysm-osteoarthritis syndrome
(MONDO_0013426)
Strong
SMAD3
(HGNC:6769)
familial thoracic aortic aneurysm and aortic dissection
(MONDO_0019625)
Limited
SMAD4
(HGNC:6770)
Myhre syndrome
(MONDO_0007688)
Definitive
SMAD4
(HGNC:6770)
pulmonary arterial hypertension
(MONDO_0015924)
Limited
SMAD4
(HGNC:6770)
juvenile polyposis syndrome
(MONDO_0017380)
Definitive
SMAD4
(HGNC:6770)
hereditary hemorrhagic telangiectasia
(MONDO_0019180)
Definitive
SMAD6
(HGNC:6772)
congenital radioulnar synostosis
(MONDO_0017985)
Strong
SMAD9
(HGNC:6774)
pulmonary arterial hypertension
(MONDO_0015924)
Definitive
MAGEL2
(HGNC:6814)
Schaaf-Yang syndrome
(MONDO_0014243)
Definitive
SMAD9
(HGNC:6774)
heritable pulmonary arterial hypertension
(MONDO_0017148)
Limited
MAN1B1
(HGNC:6823)
Rafiq syndrome
(MONDO_0013624)
Strong
MAN1B1
(HGNC:6823)
MAN1B1-congenital disorder of glycosylation
(MONDO_0018349)
Strong
MAN2B1
(HGNC:6826)
alpha-mannosidosis
(MONDO_0009561)
Definitive
MAOA
(HGNC:6833)
Brunner syndrome
(MONDO_0010379)
Strong
MAP1B
(HGNC:6836)
periventricular nodular heterotopia
(MONDO_0020341)
Moderate
MANBA
(HGNC:6831)
beta-mannosidosis
(MONDO_0009562)
Definitive
MAP2K1
(HGNC:6840)
Noonan syndrome with multiple lentigines
(MONDO_0007893)
Limited
MAP2K1
(HGNC:6840)
Costello syndrome
(MONDO_0009026)
Limited
MAP2K1
(HGNC:6840)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Definitive
MAP2K1
(HGNC:6840)
Noonan syndrome
(MONDO_0018997)
Definitive
MAP2K2
(HGNC:6842)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Strong
MAP2K2
(HGNC:6842)
neurofibromatosis-Noonan syndrome
(MONDO_0011035)
Refuted
MAP2K2
(HGNC:6842)
Noonan syndrome
(MONDO_0018997)
Moderate
MAP3K1
(HGNC:6848)
46,XY complete gonadal dysgenesis
(MONDO_0010765)
Strong
MAP3K1
(HGNC:6848)
breast cancer
(MONDO_0007254)
Moderate
MAP3K6
(HGNC:6858)
gastric cancer
(MONDO_0001056)
Disputed
MAP3K6
(HGNC:6858)
hereditary diffuse gastric adenocarcinoma
(MONDO_0007648)
Disputed
MAP3K7
(HGNC:6859)
cardiospondylocarpofacial syndrome
(MONDO_0008005)
Strong
MAP3K7
(HGNC:6859)
frontometaphyseal dysplasia
(MONDO_0015942)
Strong
MAP3K7
(HGNC:6859)
frontometaphyseal dysplasia 2
(MONDO_0014935)
Moderate
ARHGEF6
(HGNC:685)
congenital anomaly of kidney and urinary tract
(MONDO_0019719)
Strong
ARHGEF6
(HGNC:685)
X-linked intellectual disability
(MONDO_0100284)
Disputed
MAPKAPK3
(HGNC:6888)
patterned macular dystrophy 3
(MONDO_0014920)
Moderate
MAPKAPK5
(HGNC:6889)
neurocardiofaciodigital syndrome
(MONDO_0859247)
Strong
MAPT
(HGNC:6893)
Pick disease
(MONDO_0008243)
Strong
MAPT
(HGNC:6893)
semantic dementia
(MONDO_0010857)
Limited
MARS1
(HGNC:6898)
Charcot-Marie-Tooth disease axonal type 2U
(MONDO_0014566)
Limited
MARS1
(HGNC:6898)
severe early-onset pulmonary alveolar proteinosis due to MARS deficiency
(MONDO_0014206)
Strong
MATN3
(HGNC:6909)
multiple epiphyseal dysplasia type 5
(MONDO_0011765)
Moderate
ABCD4
(HGNC:68)
methylmalonic acidemia with homocystinuria, type cblJ
(MONDO_0013925)
Moderate
MAT1A
(HGNC:6903)
methionine adenosyltransferase deficiency
(MONDO_0009607)
Strong
MASP1
(HGNC:6901)
3MC syndrome
(MONDO_0017398)
Definitive
MATR3
(HGNC:6912)
distal myopathy with vocal cord weakness
(MONDO_0018951)
Limited
MC4R
(HGNC:6932)
obesity due to melanocortin 4 receptor deficiency
(MONDO_0019115)
Limited
MC4R
(HGNC:6932)
inherited obesity
(MONDO_0019182)
Strong
MCCC1
(HGNC:6936)
3-methylcrotonyl-CoA carboxylase deficiency
(MONDO_0018950)
Definitive
ARL3
(HGNC:694)
Joubert syndrome
(MONDO_0018772)
Limited
CHST6
(HGNC:6938)
macular corneal dystrophy
(MONDO_0009020)
Definitive
PHOX2A
(HGNC:691)
fibrosis of extraocular muscles, congenital, 2
(MONDO_0011181)
Strong
ARL3
(HGNC:694)
retinitis pigmentosa
(MONDO_0019200)
Moderate
PHOX2A
(HGNC:691)
congenital fibrosis of extraocular muscles
(MONDO_0007614)
Disputed
MCPH1
(HGNC:6954)
microcephaly 1, primary, autosomal recessive
(MONDO_0009617)
Definitive
MCPH1
(HGNC:6954)
autosomal recessive primary microcephaly
(MONDO_0016660)
Definitive
MDM2
(HGNC:6973)
Li-Fraumeni syndrome
(MONDO_0018875)
Limited
MC2R
(HGNC:6930)
glucocorticoid deficiency 1
(MONDO_0024536)
Definitive
MAX
(HGNC:6913)
pheochromocytoma
(MONDO_0008233)
Strong
ARL6IP1
(HGNC:697)
hereditary spastic paraplegia
(MONDO_0019064)
Strong
MECP2
(HGNC:6990)
systemic lupus erythematosus
(MONDO_0007915)
Limited
MCCC1
(HGNC:6936)
3-methylcrotonyl-CoA carboxylase 1 deficiency
(MONDO_0008861)
Strong
MECP2
(HGNC:6990)
syndromic X-linked intellectual disability Lubs type
(MONDO_0010283)
Definitive
MECP2
(HGNC:6990)
severe neonatal-onset encephalopathy with microcephaly
(MONDO_0010397)
Limited
MECP2
(HGNC:6990)
Rett syndrome
(MONDO_0010726)
Definitive
MECP2
(HGNC:6990)
atypical Rett syndrome
(MONDO_0017746)
Moderate
MECP2
(HGNC:6990)
non-syndromic X-linked intellectual disability
(MONDO_0019181)
Moderate
MEF2C
(HGNC:6996)
intellectual disability, autosomal dominant 20
(MONDO_0013266)
Moderate
MEFV
(HGNC:6998)
familial Mediterranean fever
(MONDO_0018088)
Definitive
MEIS2
(HGNC:7001)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
MEN1
(HGNC:7010)
familial isolated hyperparathyroidism
(MONDO_0015027)
Strong
MEN1
(HGNC:7010)
multiple endocrine neoplasia type 1
(MONDO_0007540)
Definitive
MEN1
(HGNC:7010)
pituitary gigantism
(MONDO_0020479)
Limited
MET
(HGNC:7029)
osteofibrous dysplasia
(MONDO_0011806)
Moderate
MET
(HGNC:7029)
hereditary papillary renal cell carcinoma
(MONDO_0003789)
Definitive
MET
(HGNC:7029)
papillary renal cell carcinoma
(MONDO_0017884)
Limited
MGAT2
(HGNC:7045)
MGAT2-congenital disorder of glycosylation
(MONDO_0008908)
Limited
MGP
(HGNC:7060)
Keutel syndrome
(MONDO_0009495)
Strong
CIITA
(HGNC:7067)
MHC class II deficiency
(MONDO_0008855)
Definitive
MID1
(HGNC:7095)
X-linked Opitz G/BBB syndrome
(MONDO_0010222)
Definitive
MIPEP
(HGNC:7104)
mitochondrial disease
(MONDO_0044970)
Moderate
MITF
(HGNC:7105)
renal cell carcinoma
(MONDO_0005086)
Limited
MITF
(HGNC:7105)
Tietz syndrome
(MONDO_0007077)
Definitive
MITF
(HGNC:7105)
Waardenburg syndrome type 2A
(MONDO_0008671)
Strong
MITF
(HGNC:7105)
Waardenburg syndrome
(MONDO_0018094)
Definitive
MITF
(HGNC:7105)
Waardenburg syndrome type 2
(MONDO_0019517)
Definitive
ATXN3
(HGNC:7106)
Machado-Joseph disease
(MONDO_0007182)
Definitive
MKS1
(HGNC:7121)
Meckel syndrome, type 1
(MONDO_0009571)
Definitive
MKS1
(HGNC:7121)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
MKS1
(HGNC:7121)
Joubert syndrome
(MONDO_0018772)
Strong
MKS1
(HGNC:7121)
Meckel syndrome
(MONDO_0018921)
Definitive
MLH1
(HGNC:7127)
rhabdomyosarcoma
(MONDO_0005212)
Limited
MLH1
(HGNC:7127)
Lynch syndrome
(MONDO_0005835)
Definitive
MLH1
(HGNC:7127)
Muir-Torre syndrome
(MONDO_0008018)
Definitive
MLH1
(HGNC:7127)
breast cancer
(MONDO_0007254)
Limited
MLH1
(HGNC:7127)
ovarian cancer
(MONDO_0008170)
Strong
MLH1
(HGNC:7127)
prostate cancer
(MONDO_0008315)
Strong
MLH1
(HGNC:7127)
mismatch repair cancer syndrome 1
(MONDO_0010159)
Definitive
MLH1
(HGNC:7127)
Lynch syndrome 2
(MONDO_0012249)
Definitive
MLH1
(HGNC:7127)
hereditary breast carcinoma
(MONDO_0016419)
Limited
KMT2A
(HGNC:7132)
Wiedemann-Steiner syndrome
(MONDO_0011518)
Definitive
KMT2D
(HGNC:7133)
Kabuki syndrome
(MONDO_0016512)
Definitive
ARSA
(HGNC:713)
metachromatic leukodystrophy, juvenile form
(MONDO_0009591)
Strong
ARSA
(HGNC:713)
metachromatic leukodystrophy
(MONDO_0018868)
Definitive
TRPM1
(HGNC:7146)
congenital stationary night blindness
(MONDO_0016293)
Definitive
MLYCD
(HGNC:7150)
malonic aciduria
(MONDO_0009556)
Definitive
MMP13
(HGNC:7159)
metaphyseal chondrodysplasia, Spahr type
(MONDO_0009597)
Strong
MMP13
(HGNC:7159)
metaphyseal anadysplasia
(MONDO_0015177)
Limited
MMP14
(HGNC:7160)
Winchester syndrome
(MONDO_0010201)
Moderate
MMP14
(HGNC:7160)
multicentric osteolysis-nodulosis-arthropathy spectrum
(MONDO_0018298)
Limited
MMP2
(HGNC:7166)
multicentric osteolysis-nodulosis-arthropathy spectrum
(MONDO_0018298)
Definitive
MMP9
(HGNC:7176)
metaphyseal anadysplasia 2
(MONDO_0013113)
Limited
ALDH6A1
(HGNC:7179)
methylmalonate semialdehyde dehydrogenase deficiency
(MONDO_0013579)
Moderate
MN1
(HGNC:7180)
CEBALID syndrome
(MONDO_0032908)
Strong
MOCS1
(HGNC:7190)
sulfite oxidase deficiency due to molybdenum cofactor deficiency type A
(MONDO_0009643)
Strong
MOCS2
(HGNC:7193)
sulfite oxidase deficiency due to molybdenum cofactor deficiency type B
(MONDO_0009644)
Definitive
ARSL
(HGNC:719)
X-linked chondrodysplasia punctata 1
(MONDO_0010555)
Strong
MPL
(HGNC:7217)
familial thrombocytosis
(MONDO_0019111)
Strong
MPST
(HGNC:7223)
encephalopathy due to beta-mercaptolactate-cysteine disulfiduria
(MONDO_0009585)
Limited
MPV17
(HGNC:7224)
Charcot-Marie-Tooth disease, axonal, type 2EE
(MONDO_0032728)
Moderate
MPV17
(HGNC:7224)
mitochondrial DNA depletion syndrome 6 (hepatocerebral type)
(MONDO_0009747)
Definitive
MPV17
(HGNC:7224)
mitochondrial disease
(MONDO_0044970)
Strong
MPZ
(HGNC:7225)
Charcot-Marie-Tooth disease type 1B
(MONDO_0007307)
Definitive
MPZ
(HGNC:7225)
Charcot-Marie-Tooth disease type 2J
(MONDO_0011903)
Strong
MPZ
(HGNC:7225)
Charcot-Marie-Tooth disease type 3
(MONDO_0007790)
Strong
MRAS
(HGNC:7227)
Noonan syndrome
(MONDO_0018997)
Definitive
MPZ
(HGNC:7225)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Definitive
MRE11
(HGNC:7230)
prostate cancer
(MONDO_0008315)
Moderate
MRE11
(HGNC:7230)
breast cancer
(MONDO_0007254)
Moderate
MS4A1
(HGNC:7315)
common variable immunodeficiency
(MONDO_0015517)
Limited
SEPTIN9
(HGNC:7323)
neuralgic amyotrophy
(MONDO_0017362)
Strong
MRE11
(HGNC:7230)
hereditary breast carcinoma
(MONDO_0016419)
Limited
MSH2
(HGNC:7325)
breast cancer
(MONDO_0007254)
Moderate
MRE11
(HGNC:7230)
ataxia-telangiectasia-like disorder 1
(MONDO_0024557)
Limited
MSH2
(HGNC:7325)
prostate cancer
(MONDO_0008315)
Strong
MSH2
(HGNC:7325)
rhabdomyosarcoma
(MONDO_0005212)
Limited
MSH3
(HGNC:7326)
Lynch syndrome
(MONDO_0005835)
Limited
MSH2
(HGNC:7325)
Muir-Torre syndrome
(MONDO_0008018)
Definitive
MSH2
(HGNC:7325)
mismatch repair cancer syndrome 1
(MONDO_0010159)
Strong
MSH2
(HGNC:7325)
hereditary breast carcinoma
(MONDO_0016419)
Limited
MSH6
(HGNC:7329)
Lynch syndrome
(MONDO_0005835)
Definitive
MSH6
(HGNC:7329)
breast cancer
(MONDO_0007254)
Moderate
MSH6
(HGNC:7329)
mismatch repair cancer syndrome 1
(MONDO_0010159)
Definitive
MSH6
(HGNC:7329)
hereditary breast carcinoma
(MONDO_0016419)
Moderate
MSH6
(HGNC:7329)
Muir-Torre syndrome
(MONDO_0008018)
Moderate
MSL3
(HGNC:7370)
Basilicata-Akhtar syndrome
(MONDO_0026730)
Definitive
MSN
(HGNC:7373)
combined immunodeficiency due to moesin deficiency
(MONDO_0010514)
Strong
MSR1
(HGNC:7376)
Barrett esophagus
(MONDO_0013662)
Moderate
MSH2
(HGNC:7325)
ovarian cancer
(MONDO_0008170)
Strong
MST1
(HGNC:7380)
epidermodysplasia verruciformis
(MONDO_0009176)
Limited
MSX1
(HGNC:7391)
tooth and nail syndrome
(MONDO_0008582)
Strong
MSX2
(HGNC:7392)
parietal foramina with cleidocranial dysplasia
(MONDO_0008198)
Moderate
MSH6
(HGNC:7329)
ovarian cancer
(MONDO_0008170)
Definitive
MT-ATP6
(HGNC:7414)
Leigh syndrome
(MONDO_0009723)
Strong
MT-ATP6
(HGNC:7414)
Leber hereditary optic neuropathy
(MONDO_0010788)
Limited
MSH6
(HGNC:7329)
prostate cancer
(MONDO_0008315)
Moderate
MT-ATP6
(HGNC:7414)
NARP syndrome
(MONDO_0010794)
Strong
MT-ATP6
(HGNC:7414)
mitochondrial disease
(MONDO_0044970)
Definitive
MT-ATP8
(HGNC:7415)
mitochondrial disease
(MONDO_0044970)
Limited
MT-CO1
(HGNC:7419)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Limited
MT-CO1
(HGNC:7419)
Leigh syndrome
(MONDO_0009723)
Limited
MT-CO1
(HGNC:7419)
MELAS syndrome
(MONDO_0010789)
Limited
MT-CO1
(HGNC:7419)
mitochondrial disease
(MONDO_0044970)
Limited
MT-CO2
(HGNC:7421)
cytochrome-c oxidase deficiency disease
(MONDO_0009068)
Limited
MT-CO2
(HGNC:7421)
Leigh syndrome
(MONDO_0009723)
Limited
MT-CO2
(HGNC:7421)
MELAS syndrome
(MONDO_0010789)
Limited
MT-CO2
(HGNC:7421)
mitochondrial disease
(MONDO_0044970)
Strong
MT-CO3
(HGNC:7422)
Leigh syndrome
(MONDO_0009723)
Limited
MT-CO3
(HGNC:7422)
Leber hereditary optic neuropathy
(MONDO_0010788)
Definitive
MT-CO3
(HGNC:7422)
mitochondrial disease
(MONDO_0044970)
Strong
MT-ATP6
(HGNC:7414)
maternally-inherited Leigh syndrome
(MONDO_0016814)
Definitive
MT-CYB
(HGNC:7427)
Leber hereditary optic neuropathy
(MONDO_0010788)
Strong
MT-CYB
(HGNC:7427)
mitochondrial complex III deficiency
(MONDO_0015448)
Moderate
MT-CYB
(HGNC:7427)
mitochondrial disease
(MONDO_0044970)
Moderate
MTHFR
(HGNC:7436)
homocystinuria due to methylene tetrahydrofolate reductase deficiency
(MONDO_0009353)
Definitive
MTMR2
(HGNC:7450)
Charcot-Marie-Tooth disease type 4B1
(MONDO_0011066)
Definitive
MT-ND1
(HGNC:7455)
Leigh syndrome
(MONDO_0009723)
Strong
MT-ND1
(HGNC:7455)
Leber hereditary optic neuropathy
(MONDO_0010788)
Definitive
MT-ND1
(HGNC:7455)
MELAS syndrome
(MONDO_0010789)
Moderate
MT-ND1
(HGNC:7455)
mitochondrial disease
(MONDO_0044970)
Moderate
MT-ND1
(HGNC:7455)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
MT-ND2
(HGNC:7456)
Leber hereditary optic neuropathy
(MONDO_0010788)
Limited
MT-ND2
(HGNC:7456)
mitochondrial disease
(MONDO_0044970)
Limited
MT-ND2
(HGNC:7456)
mitochondrial complex I deficiency
(MONDO_0100133)
Moderate
MT-ND3
(HGNC:7458)
Leigh syndrome
(MONDO_0009723)
Strong
MT-ND2
(HGNC:7456)
Leigh syndrome
(MONDO_0009723)
Limited
MT-ND3
(HGNC:7458)
mitochondrial disease
(MONDO_0044970)
Strong
MT-ND3
(HGNC:7458)
mitochondrial complex I deficiency
(MONDO_0100133)
Moderate
MT-ND4
(HGNC:7459)
Leigh syndrome
(MONDO_0009723)
Strong
MT-ND4
(HGNC:7459)
Leber hereditary optic neuropathy
(MONDO_0010788)
Definitive
MT-ND4
(HGNC:7459)
MELAS syndrome
(MONDO_0010789)
Limited
MT-ND4
(HGNC:7459)
mitochondrial disease
(MONDO_0044970)
Moderate
MT-ND4L
(HGNC:7460)
Leber hereditary optic neuropathy
(MONDO_0010788)
Definitive
MT-ND4L
(HGNC:7460)
mitochondrial disease
(MONDO_0044970)
Limited
MT-ND5
(HGNC:7461)
Leigh syndrome
(MONDO_0009723)
Definitive
MT-ND5
(HGNC:7461)
Leber hereditary optic neuropathy
(MONDO_0010788)
Strong
MT-ND5
(HGNC:7461)
MELAS syndrome
(MONDO_0010789)
Strong
MT-ND5
(HGNC:7461)
mitochondrial disease
(MONDO_0044970)
Definitive
MT-ND6
(HGNC:7462)
Leigh syndrome
(MONDO_0009723)
Strong
MT-ND6
(HGNC:7462)
Leber hereditary optic neuropathy
(MONDO_0010788)
Definitive
MT-ND6
(HGNC:7462)
MELAS syndrome
(MONDO_0010789)
Limited
MT-ND6
(HGNC:7462)
mitochondrial disease
(MONDO_0044970)
Moderate
MTX2
(HGNC:7506)
mandibuloacral dysplasia
(MONDO_0016584)
Limited
MTR
(HGNC:7468)
methylcobalamin deficiency type cblG
(MONDO_0009609)
Strong
MTX2
(HGNC:7506)
mandibuloacral dysplasia progeroid syndrome
(MONDO_0030880)
Limited
MUC1
(HGNC:7508)
tubulointerstitial kidney disease, autosomal dominant, 2
(MONDO_0020726)
Definitive
MUC5B
(HGNC:7516)
interstitial lung disease
(MONDO_0015925)
Moderate
MUSK
(HGNC:7525)
fetal akinesia deformation sequence 1
(MONDO_0100101)
Limited
MUTYH
(HGNC:7527)
colorectal cancer
(MONDO_0005575)
Definitive
MUTYH
(HGNC:7527)
familial ovarian cancer
(MONDO_0016248)
Limited
MUTYH
(HGNC:7527)
familial adenomatous polyposis 2
(MONDO_0012041)
Definitive
MUTYH
(HGNC:7527)
hereditary breast carcinoma
(MONDO_0016419)
Disputed
MVD
(HGNC:7529)
disseminated superficial actinic porokeratosis
(MONDO_0019212)
Strong
TRIM37
(HGNC:7523)
mulibrey nanism
(MONDO_0009664)
Definitive
MVK
(HGNC:7530)
hyperimmunoglobulinemia D with periodic fever
(MONDO_0009849)
Definitive
MVK
(HGNC:7530)
mevalonic aciduria
(MONDO_0012481)
Strong
MYBPC3
(HGNC:7551)
atrial fibrillation
(MONDO_0004981)
Limited
MYBPC3
(HGNC:7551)
dilated cardiomyopathy
(MONDO_0005021)
Strong
MYBPC3
(HGNC:7551)
hypertrophic cardiomyopathy
(MONDO_0005045)
Definitive
MYBPC3
(HGNC:7551)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
MYH3
(HGNC:7573)
contractures, pterygia, and spondylocarpotarsal fusion syndrome 1A
(MONDO_0008338)
Limited
MYD88
(HGNC:7562)
pyogenic bacterial infections due to MyD88 deficiency
(MONDO_0012839)
Moderate
MYCN
(HGNC:7559)
Feingold syndrome type 1
(MONDO_0008115)
Definitive
MVK
(HGNC:7530)
disseminated superficial actinic porokeratosis
(MONDO_0019212)
Strong
MYH3
(HGNC:7573)
Freeman-Sheldon syndrome
(MONDO_0008675)
Strong
MYH3
(HGNC:7573)
spondylocarpotarsal synostosis syndrome
(MONDO_0010094)
Strong
MYH3
(HGNC:7573)
Sheldon-hall syndrome
(MONDO_0011128)
Strong
MYH3
(HGNC:7573)
contractures, pterygia, and variable skeletal fusions syndrome 1B
(MONDO_0020746)
Moderate
MYH6
(HGNC:7576)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
MYH7
(HGNC:7577)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
MYH6
(HGNC:7576)
hypertrophic cardiomyopathy
(MONDO_0005045)
Moderate
MYH7
(HGNC:7577)
hypertrophic cardiomyopathy
(MONDO_0005045)
Strong
MYH7
(HGNC:7577)
congenital heart disease
(MONDO_0005453)
Moderate
MYH7
(HGNC:7577)
MYH7-related skeletal myopathy
(MONDO_0008050)
Strong
MYH7
(HGNC:7577)
congenital myopathy 7A, myosin storage, autosomal dominant
(MONDO_0008409)
Definitive
MYH8
(HGNC:7578)
trismus-pseudocamptodactyly syndrome
(MONDO_0008016)
Strong
MYH7
(HGNC:7577)
Ebstein anomaly
(MONDO_0009144)
Strong
MYH7
(HGNC:7577)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
MYH7
(HGNC:7577)
left ventricular noncompaction
(MONDO_0018901)
Definitive
MYH9
(HGNC:7579)
macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss
(MONDO_0015912)
Definitive
MYL1
(HGNC:7582)
congenital myopathy
(MONDO_0019952)
Moderate
MYL2
(HGNC:7583)
dilated cardiomyopathy
(MONDO_0005021)
Limited
MYO15A
(HGNC:7594)
autosomal recessive nonsyndromic hearing loss 3
(MONDO_0010860)
Definitive
MYO6
(HGNC:7605)
autosomal dominant nonsyndromic hearing loss 22
(MONDO_0011660)
Moderate
MYO5A
(HGNC:7602)
Griscelli syndrome type 1
(MONDO_0008962)
Strong
MYO7A
(HGNC:7606)
Usher syndrome type 2
(MONDO_0016484)
Limited
MYO7A
(HGNC:7606)
autosomal recessive nonsyndromic hearing loss 2
(MONDO_0010807)
Moderate
MYO7A
(HGNC:7606)
autosomal dominant nonsyndromic hearing loss 11
(MONDO_0011032)
Strong
MYO7A
(HGNC:7606)
Usher syndrome type 1B
(MONDO_0700087)
Definitive
MYL2
(HGNC:7583)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
MYL2
(HGNC:7583)
congenital fiber-type disproportion myopathy
(MONDO_0009711)
Limited
MYT1
(HGNC:7622)
craniofacial microsomia
(MONDO_0015397)
Strong
MYOC
(HGNC:7610)
congenital glaucoma
(MONDO_0020366)
Limited
NAGA
(HGNC:7631)
alpha-N-acetylgalactosaminidase deficiency type 1
(MONDO_0012221)
Strong
NBN
(HGNC:7652)
prostate cancer
(MONDO_0008315)
Strong
NAGA
(HGNC:7631)
alpha-N-acetylgalactosaminidase deficiency
(MONDO_0017779)
Limited
MYL3
(HGNC:7584)
dilated cardiomyopathy
(MONDO_0005021)
Moderate
NBN
(HGNC:7652)
Nijmegen breakage syndrome
(MONDO_0009623)
Definitive
NBN
(HGNC:7652)
hereditary breast carcinoma
(MONDO_0016419)
Limited
MYL3
(HGNC:7584)
hypertrophic cardiomyopathy
(MONDO_0005045)
Definitive
NCF2
(HGNC:7661)
chronic granulomatous disease
(MONDO_0018305)
Strong
NCF4
(HGNC:7662)
chronic granulomatous disease
(MONDO_0018305)
Strong
NDRG1
(HGNC:7679)
Charcot-Marie-Tooth disease type 4D
(MONDO_0011085)
Strong
MYL3
(HGNC:7584)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Limited
NDUFA1
(HGNC:7683)
Leigh syndrome
(MONDO_0009723)
Limited
NDUFA1
(HGNC:7683)
mitochondrial complex I deficiency
(MONDO_0100133)
Moderate
NDUFA2
(HGNC:7685)
Leigh syndrome
(MONDO_0009723)
Limited
NDST1
(HGNC:7680)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Strong
NDUFA3
(HGNC:7686)
Leigh syndrome
(MONDO_0009723)
Limited
NDUFA6
(HGNC:7690)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFA4
(HGNC:7687)
Leigh syndrome
(MONDO_0009723)
Moderate
NDUFB3
(HGNC:7698)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
ABL1
(HGNC:76)
congenital heart defects and skeletal malformations syndrome
(MONDO_0060532)
Definitive
NDUFB8
(HGNC:7703)
Leigh syndrome
(MONDO_0009723)
Moderate
NDUFB9
(HGNC:7704)
mitochondrial complex I deficiency
(MONDO_0100133)
Limited
NDUFS1
(HGNC:7707)
Leigh syndrome
(MONDO_0009723)
Strong
NDUFS1
(HGNC:7707)
mitochondrial disease
(MONDO_0044970)
Strong
NDUFS1
(HGNC:7707)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFS2
(HGNC:7708)
Leigh syndrome
(MONDO_0009723)
Strong
NDUFS2
(HGNC:7708)
Leber hereditary optic neuropathy
(MONDO_0010788)
Limited
NDUFS2
(HGNC:7708)
mitochondrial complex I deficiency
(MONDO_0100133)
Definitive
NDUFS3
(HGNC:7710)
Leigh syndrome
(MONDO_0009723)
Moderate
NDUFS3
(HGNC:7710)
mitochondrial complex I deficiency
(MONDO_0100133)
Limited
NDUFS4
(HGNC:7711)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFS6
(HGNC:7713)
mitochondrial disease
(MONDO_0044970)
Moderate
NDUFS6
(HGNC:7713)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFS7
(HGNC:7714)
Leigh syndrome
(MONDO_0009723)
Strong
NDUFS7
(HGNC:7714)
mitochondrial complex I deficiency
(MONDO_0100133)
Limited
NDUFS8
(HGNC:7715)
Leigh syndrome
(MONDO_0009723)
Strong
NDUFS8
(HGNC:7715)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFV1
(HGNC:7716)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NDUFV2
(HGNC:7717)
Leigh syndrome
(MONDO_0009723)
Strong
NDUFV2
(HGNC:7717)
mitochondrial complex I deficiency
(MONDO_0100133)
Strong
NEB
(HGNC:7720)
lethal multiple pterygium syndrome
(MONDO_0009668)
Limited
NEDD4L
(HGNC:7728)
periventricular nodular heterotopia
(MONDO_0020341)
Strong
NEFH
(HGNC:7737)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
NEFL
(HGNC:7739)
Charcot-Marie-Tooth disease type 2
(MONDO_0018993)
Moderate
NEK1
(HGNC:7744)
orofaciodigital syndrome type II
(MONDO_0009642)
Moderate
NEU1
(HGNC:7758)
sialidosis type 2
(MONDO_0009738)
Definitive
NEU1
(HGNC:7758)
sialidosis type 1
(MONDO_0019346)
Definitive
SERPINC1
(HGNC:775)
hereditary antithrombin deficiency
(MONDO_0013144)
Definitive
NEUROD1
(HGNC:7762)
maturity-onset diabetes of the young type 6
(MONDO_0011668)
Moderate
NEUROD1
(HGNC:7762)
monogenic diabetes
(MONDO_0015967)
Limited
NEUROD1
(HGNC:7762)
maturity-onset diabetes of the young
(MONDO_0018911)
Limited
NF1
(HGNC:7765)
neurofibromatosis-Noonan syndrome
(MONDO_0011035)
Strong
NF1
(HGNC:7765)
Moyamoya disease
(MONDO_0016820)
Moderate
NF1
(HGNC:7765)
neurofibromatosis type 1
(MONDO_0018975)
Definitive
NF2
(HGNC:7773)
NF2-related schwannomatosis
(MONDO_0007039)
Definitive
NFATC1
(HGNC:7775)
congenital heart disease
(MONDO_0005453)
Moderate
ZFHX3
(HGNC:777)
epilepsy
(MONDO_0005027)
Moderate
ZFHX3
(HGNC:777)
spinocerebellar ataxia type 4
(MONDO_0010847)
Strong
NFKB1
(HGNC:7794)
common variable immunodeficiency
(MONDO_0015517)
Definitive
NFKB2
(HGNC:7795)
deficiency in anterior pituitary function - variable immunodeficiency syndrome
(MONDO_0017407)
Strong
NFKBIA
(HGNC:7797)
ectodermal dysplasia and immune deficiency
(MONDO_0010293)
Strong
ATCAY
(HGNC:779)
Cayman type cerebellar ataxia
(MONDO_0011025)
Moderate
NGF
(HGNC:7808)
hereditary sensory and autonomic neuropathy type 5
(MONDO_0012092)
Strong
NGF
(HGNC:7808)
hereditary sensory and autonomic neuropathy
(MONDO_0015364)
Strong
NOG
(HGNC:7866)
stapes ankylosis with broad thumbs and toes
(MONDO_0008484)
Strong
NOG
(HGNC:7866)
multiple synostoses syndrome 1
(MONDO_0008519)
Strong
NOG
(HGNC:7866)
tarsal-carpal coalition syndrome
(MONDO_0008521)
Limited
NOG
(HGNC:7866)
brachydactyly type B2
(MONDO_0012658)
Limited
NOG
(HGNC:7866)
multiple synostoses syndrome
(MONDO_0017923)
Definitive
NONO
(HGNC:7871)
syndromic X-linked intellectual disability 34
(MONDO_0010501)
Strong
CNOT1
(HGNC:7877)
Vissers-Bodmer syndrome
(MONDO_0033618)
Definitive
CNOT2
(HGNC:7878)
intellectual developmental disorder with nasal speech, dysmorphic facies, and variable skeletal anomalies
(MONDO_0032832)
Strong
NOTCH1
(HGNC:7881)
connective tissue disorder
(MONDO_0003900)
Limited
CNOT3
(HGNC:7879)
intellectual developmental disorder with speech delay, autism, and dysmorphic facies
(MONDO_0032864)
Strong
NOTCH1
(HGNC:7881)
familial bicuspid aortic valve
(MONDO_0007194)
Limited
NOTCH1
(HGNC:7881)
Adams-Oliver syndrome
(MONDO_0007034)
Strong
NOTCH2
(HGNC:7882)
Acroosteolysis dominant type
(MONDO_0007057)
Definitive
NOTCH2
(HGNC:7882)
Alagille syndrome
(MONDO_0007318)
Strong
NOTCH2
(HGNC:7882)
Alagille syndrome due to a NOTCH2 point mutation
(MONDO_0012439)
Moderate
NOTCH3
(HGNC:7883)
cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1
(MONDO_0000914)
Definitive
NOTCH3
(HGNC:7883)
pulmonary arterial hypertension
(MONDO_0015924)
Limited
NOTCH3
(HGNC:7883)
lateral meningocele syndrome
(MONDO_0007537)
Strong
NOTCH3
(HGNC:7883)
infantile myofibromatosis
(MONDO_0016824)
Limited
NPC1
(HGNC:7897)
Niemann-Pick disease, type C1
(MONDO_0009757)
Definitive
NPHP1
(HGNC:7905)
nephronophthisis 1
(MONDO_0009728)
Definitive
NPHP1
(HGNC:7905)
Bardet-Biedl syndrome
(MONDO_0015229)
Limited
NPHP1
(HGNC:7905)
Senior-Loken syndrome
(MONDO_0017842)
Definitive
NPHP3
(HGNC:7907)
nephronophthisis 3
(MONDO_0011456)
Strong
NPHP3
(HGNC:7907)
renal-hepatic-pancreatic dysplasia
(MONDO_0017417)
Moderate
NPHP3
(HGNC:7907)
Senior-Loken syndrome
(MONDO_0017842)
Limited
NPHS1
(HGNC:7908)
congenital nephrotic syndrome, Finnish type
(MONDO_0009732)
Definitive
ATF6
(HGNC:791)
cone-rod dystrophy
(MONDO_0015993)
Strong
ATF6
(HGNC:791)
achromatopsia
(MONDO_0018852)
Strong
NPR2
(HGNC:7944)
tall stature-scoliosis-macrodactyly of the great toes syndrome
(MONDO_0014401)
Moderate
ATM
(HGNC:795)
gastric carcinoma
(MONDO_0004950)
Limited
NPR2
(HGNC:7944)
short stature with nonspecific skeletal abnormalities
(MONDO_0014551)
Strong
ATIC
(HGNC:794)
AICA-ribosiduria
(MONDO_0012099)
Strong
ATM
(HGNC:795)
prostate cancer
(MONDO_0008315)
Strong
ATM
(HGNC:795)
sarcoma
(MONDO_0005089)
Moderate
ATM
(HGNC:795)
ataxia telangiectasia
(MONDO_0008840)
Definitive
ATM
(HGNC:795)
hereditary nonpolyposis colon cancer
(MONDO_0018630)
Limited
NR1H4
(HGNC:7967)
cholestasis, progressive familial intrahepatic, 5
(MONDO_0014884)
Moderate
NR2E1
(HGNC:7973)
microcephaly
(MONDO_0001149)
Limited
ATM
(HGNC:795)
hereditary breast carcinoma
(MONDO_0016419)
Moderate
NR2E3
(HGNC:7974)
Goldmann-Favre syndrome
(MONDO_0100289)
Moderate
NR0B1
(HGNC:7960)
X-linked adrenal hypoplasia congenita
(MONDO_0010264)
Definitive
NR3C1
(HGNC:7978)
glucocorticoid resistance
(MONDO_0014421)
Moderate
NR2E3
(HGNC:7974)
retinitis pigmentosa
(MONDO_0019200)
Definitive
NR3C2
(HGNC:7979)
autosomal dominant pseudohypoaldosteronism type 1
(MONDO_0008329)
Definitive
NR5A1
(HGNC:7983)
46,XY complete gonadal dysgenesis
(MONDO_0010765)
Strong
NR5A1
(HGNC:7983)
46,XY partial gonadal dysgenesis
(MONDO_0016674)
Strong
NRAS
(HGNC:7989)
Noonan syndrome with multiple lentigines
(MONDO_0007893)
Limited
NR4A2
(HGNC:7981)
neurodevelopmental disorder
(MONDO_0700092)
Strong
NRAS
(HGNC:7989)
Costello syndrome
(MONDO_0009026)
Refuted
NRAS
(HGNC:7989)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Limited
NRAS
(HGNC:7989)
Noonan syndrome
(MONDO_0018997)
Strong
NRP1
(HGNC:8004)
congenital heart disease
(MONDO_0005453)
Limited
NRXN1
(HGNC:8008)
schizophrenia
(MONDO_0005090)
Strong
NRL
(HGNC:8002)
enhanced S-cone syndrome
(MONDO_0100288)
Limited
NRL
(HGNC:8002)
retinitis pigmentosa
(MONDO_0019200)
Definitive
NRXN1
(HGNC:8008)
autism
(MONDO_0005260)
Strong
NRXN1
(HGNC:8008)
Pitt-Hopkins-like syndrome 2
(MONDO_0013690)
Limited
ATP1A2
(HGNC:800)
alternating hemiplegia of childhood 1
(MONDO_0007087)
Limited
NRXN2
(HGNC:8009)
autism
(MONDO_0005260)
Limited
ATP1A2
(HGNC:800)
migraine, familial hemiplegic, 2
(MONDO_0011232)
Definitive
ATP1A2
(HGNC:800)
alternating hemiplegia of childhood
(MONDO_0016241)
Moderate
NRXN3
(HGNC:8010)
autism
(MONDO_0005260)
Limited
ATP1A3
(HGNC:801)
dystonia 12
(MONDO_0007496)
Definitive
ATP1A3
(HGNC:801)
cerebellar ataxia-areflexia-pes cavus-optic atrophy-sensorineural hearing loss syndrome
(MONDO_0011038)
Definitive
CNTNAP1
(HGNC:8011)
lethal congenital contracture syndrome 7
(MONDO_0014569)
Moderate
NT5E
(HGNC:8021)
hereditary arterial and articular multiple calcification syndrome
(MONDO_0008895)
Strong
ATP1A3
(HGNC:801)
alternating hemiplegia of childhood 2
(MONDO_0013900)
Definitive
ATP1A3
(HGNC:801)
alternating hemiplegia of childhood
(MONDO_0016241)
Definitive
NT5C2
(HGNC:8022)
hereditary spastic paraplegia 45
(MONDO_0013165)
Strong
NTN1
(HGNC:8029)
familial congenital mirror movements
(MONDO_0016558)
Moderate
NTRK1
(HGNC:8031)
hereditary sensory and autonomic neuropathy type 4
(MONDO_0009746)
Definitive
NTHL1
(HGNC:8028)
breast cancer
(MONDO_0007254)
Limited
NUP88
(HGNC:8067)
fetal akinesia deformation sequence 1
(MONDO_0100101)
Strong
NTRK3
(HGNC:8033)
congenital heart disease
(MONDO_0005453)
Moderate
NYX
(HGNC:8082)
congenital stationary night blindness
(MONDO_0016293)
Definitive
OCA2
(HGNC:8101)
oculocutaneous albinism type 2
(MONDO_0008746)
Definitive
OCRL
(HGNC:8108)
Dent disease type 2
(MONDO_0010359)
Definitive
ODC1
(HGNC:8109)
neurodevelopmental disorder with alopecia and brain abnormalities
(MONDO_0033642)
Strong
TENM1
(HGNC:8117)
cerebral palsy
(MONDO_0006497)
Limited
ATP2A1
(HGNC:811)
Brody myopathy
(MONDO_0010977)
Definitive
OGDH
(HGNC:8124)
oxoglutaricaciduria
(MONDO_0008759)
Strong
ONECUT1
(HGNC:8138)
neonatal diabetes mellitus
(MONDO_0016391)
Moderate
OPLAH
(HGNC:8149)
5-oxoprolinase deficiency
(MONDO_0009825)
Limited
OPA3
(HGNC:8142)
3-methylglutaconic aciduria type 3
(MONDO_0009787)
Strong
SIGMAR1
(HGNC:8157)
autosomal recessive distal spinal muscular atrophy 2
(MONDO_0011585)
Strong
SIGMAR1
(HGNC:8157)
juvenile amyotrophic lateral sclerosis
(MONDO_0017593)
Limited
ATP5F1A
(HGNC:823)
mitochondrial disease
(MONDO_0044970)
Moderate
ORC1
(HGNC:8487)
Meier-Gorlin syndrome
(MONDO_0016817)
Definitive
ORC4
(HGNC:8490)
Meier-Gorlin syndrome
(MONDO_0016817)
Strong
ACACA
(HGNC:84)
acetyl-coa carboxylase deficiency
(MONDO_0013493)
Limited
OSMR
(HGNC:8507)
familial primary localized cutaneous amyloidosis
(MONDO_0007101)
Strong
OTOF
(HGNC:8515)
autosomal recessive nonsyndromic hearing loss 9
(MONDO_0010986)
Definitive
ATP6V1A
(HGNC:851)
developmental and epileptic encephalopathy 93
(MONDO_0020632)
Strong
ATP6V1A
(HGNC:851)
autosomal recessive cutis laxa type 2D
(MONDO_0027451)
Strong
OXCT1
(HGNC:8527)
succinyl-CoA:3-ketoacid CoA transferase deficiency
(MONDO_0009492)
Strong
P2RX6
(HGNC:8538)
myopathy
(MONDO_0005336)
Limited
ATP6V1B1
(HGNC:853)
autosomal recessive distal renal tubular acidosis
(MONDO_0018440)
Definitive
P4HA2
(HGNC:8547)
myopia
(MONDO_0001384)
Moderate
P4HB
(HGNC:8548)
Cole-Carpenter syndrome 1
(MONDO_0007204)
Limited
P4HB
(HGNC:8548)
Cole-Carpenter syndrome
(MONDO_0016085)
Moderate
BLOC1S6
(HGNC:8549)
Hermansky-Pudlak syndrome 9
(MONDO_0013606)
Limited
ATP6V1B2
(HGNC:854)
Zimmermann-Laband syndrome
(MONDO_0000200)
Strong
ATP6V1B2
(HGNC:854)
autosomal dominant deafness - onychodystrophy syndrome
(MONDO_0007420)
Strong
ATP6V1B2
(HGNC:854)
Zimmermann-Laband syndrome 2
(MONDO_0014646)
Limited
PAH
(HGNC:8582)
phenylketonuria
(MONDO_0009861)
Definitive
ATP6V1B2
(HGNC:854)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
PAH
(HGNC:8582)
maternal phenylketonuria
(MONDO_0016366)
Definitive
PAH
(HGNC:8582)
mild phenylketonuria
(MONDO_0019258)
Definitive
PAH
(HGNC:8582)
classic phenylketonuria
(MONDO_0019259)
Definitive
PAH
(HGNC:8582)
mild hyperphenylalaninemia
(MONDO_0019335)
Definitive
PAK1
(HGNC:8590)
intellectual developmental disorder with macrocephaly, seizures, and speech delay
(MONDO_0032568)
Strong
PAK2
(HGNC:8591)
Knobloch syndrome 2
(MONDO_0100119)
Strong
PRKN
(HGNC:8607)
Parkinson disease
(MONDO_0005180)
Definitive
PRKN
(HGNC:8607)
autosomal recessive juvenile Parkinson disease 2
(MONDO_0010820)
Strong
PRKN
(HGNC:8607)
young-onset Parkinson disease
(MONDO_0017279)
Definitive
PARN
(HGNC:8609)
dyskeratosis congenita
(MONDO_0015780)
Strong
PAX1
(HGNC:8615)
otofaciocervical syndrome 2
(MONDO_0014254)
Strong
PAX2
(HGNC:8616)
renal coloboma syndrome
(MONDO_0007352)
Definitive
PAX3
(HGNC:8617)
craniofacial-deafness-hand syndrome
(MONDO_0007395)
Limited
PARN
(HGNC:8609)
Hoyeraal-Hreidarsson syndrome
(MONDO_0018045)
Strong
PAX3
(HGNC:8617)
Waardenburg syndrome type 3
(MONDO_0007862)
Moderate
PAX2
(HGNC:8616)
focal segmental glomerulosclerosis 7
(MONDO_0014451)
Limited
PAX4
(HGNC:8618)
maturity-onset diabetes of the young type 9
(MONDO_0012818)
Strong
PAX6
(HGNC:8620)
diabetes mellitus
(MONDO_0005015)
Moderate
PAX4
(HGNC:8618)
monogenic diabetes
(MONDO_0015967)
Strong
PAX6
(HGNC:8620)
aniridia-cerebellar ataxia-intellectual disability syndrome
(MONDO_0008795)
Disputed
PAX6
(HGNC:8620)
Peters anomaly
(MONDO_0011414)
Limited
PBX1
(HGNC:8632)
congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay
(MONDO_0060549)
Strong
PAX8
(HGNC:8622)
athyreosis
(MONDO_0019855)
Limited
PCDH12
(HGNC:8657)
diencephalic-mesencephalic junction dysplasia syndrome 1
(MONDO_0009625)
Limited
PC
(HGNC:8636)
pyruvate carboxylase deficiency disease
(MONDO_0009949)
Definitive
PCDH12
(HGNC:8657)
diencephalic-mesencephalic junction dysplasia
(MONDO_0017868)
Strong
ATP7A
(HGNC:869)
X-linked distal spinal muscular atrophy type 3
(MONDO_0010338)
Limited
ATP6V0A4
(HGNC:866)
autosomal recessive distal renal tubular acidosis
(MONDO_0018440)
Strong
PCK1
(HGNC:8724)
phosphoenolpyruvate carboxykinase deficiency, cytosolic
(MONDO_0009866)
Strong
PAX6
(HGNC:8620)
autosomal dominant keratitis
(MONDO_0007848)
Strong
PCK1
(HGNC:8724)
phosphoenolpyruvate carboxykinase deficiency
(MONDO_0017320)
Limited
ATP7A
(HGNC:869)
Hirschsprung disease
(MONDO_0018309)
Limited
CHMP1A
(HGNC:8740)
pontocerebellar hypoplasia type 8
(MONDO_0013990)
Limited
PDCD1
(HGNC:8760)
systemic lupus erythematosus
(MONDO_0007915)
Moderate
PCYT1A
(HGNC:8754)
spondylometaphyseal dysplasia-cone-rod dystrophy syndrome
(MONDO_0012160)
Strong
PDCD10
(HGNC:8761)
cerebral cavernous malformation 3
(MONDO_0011305)
Definitive
PAX4
(HGNC:8618)
maturity-onset diabetes of the young
(MONDO_0018911)
Strong
AIFM1
(HGNC:8768)
spondyloepimetaphyseal dysplasia, Bieganski type
(MONDO_0010275)
Strong
PDCD10
(HGNC:8761)
famililal cerebral cavernous malformations
(MONDO_0031037)
Strong
PDE11A
(HGNC:8773)
primary pigmented nodular adrenocortical disease
(MONDO_0015999)
Limited
AIFM1
(HGNC:8768)
Charcot-Marie-Tooth disease X-linked recessive 4
(MONDO_0010689)
Strong
PDE2A
(HGNC:8777)
intellectual developmental disorder with paroxysmal dyskinesia or seizures
(MONDO_0030900)
Strong
PDE3A
(HGNC:8778)
brachydactyly-arterial hypertension syndrome
(MONDO_0007211)
Definitive
PDE4D
(HGNC:8783)
acrodysostosis
(MONDO_0019797)
Strong
PDE6A
(HGNC:8785)
retinitis pigmentosa
(MONDO_0019200)
Definitive
PDE6B
(HGNC:8786)
congenital stationary night blindness
(MONDO_0016293)
Limited
PDE6C
(HGNC:8787)
cone dystrophy
(MONDO_0000455)
Strong
PDE6C
(HGNC:8787)
achromatopsia
(MONDO_0018852)
Definitive
PDE8B
(HGNC:8794)
primary pigmented nodular adrenocortical disease
(MONDO_0015999)
Limited
PDE6H
(HGNC:8790)
achromatopsia
(MONDO_0018852)
Moderate
PDGFRA
(HGNC:8803)
polyps, multiple and recurrent inflammatory fibroid, gastrointestinal
(MONDO_0008285)
Limited
PDGFRA
(HGNC:8803)
gastrointestinal stromal tumor
(MONDO_0011719)
Definitive
PDGFRB
(HGNC:8804)
acroosteolysis-keloid-like lesions-premature aging syndrome
(MONDO_0011150)
Strong
PDGFRB
(HGNC:8804)
skeletal overgrowth-craniofacial dysmorphism-hyperelastic skin-white matter lesions syndrome
(MONDO_0014704)
Strong
PDHA1
(HGNC:8806)
Leigh syndrome
(MONDO_0009723)
Strong
PDGFRB
(HGNC:8804)
infantile myofibromatosis
(MONDO_0016824)
Definitive
PDHB
(HGNC:8808)
Leigh syndrome
(MONDO_0009723)
Strong
PDK3
(HGNC:8811)
Charcot-Marie-Tooth disease X-linked dominant 6
(MONDO_0010479)
Strong
SLC26A4
(HGNC:8818)
Pendred syndrome
(MONDO_0010134)
Definitive
SLC26A4
(HGNC:8818)
autosomal recessive nonsyndromic hearing loss 4
(MONDO_0010933)
Strong
PDYN
(HGNC:8820)
spinocerebellar ataxia type 23
(MONDO_0012449)
Strong
SERPINF1
(HGNC:8824)
osteogenesis imperfecta type 6
(MONDO_0013515)
Strong
PEX1
(HGNC:8850)
peroxisome biogenesis disorder 1B
(MONDO_0011101)
Definitive
PEX10
(HGNC:8851)
peroxisome biogenesis disorder 6B
(MONDO_0013937)
Strong
PEX10
(HGNC:8851)
peroxisome biogenesis disorder
(MONDO_0019234)
Definitive
PEX10
(HGNC:8851)
Zellweger spectrum disorders
(MONDO_0019609)
Strong
PEX11B
(HGNC:8853)
peroxisome biogenesis disorder 14B
(MONDO_0013967)
Limited
PEX14
(HGNC:8856)
peroxisome biogenesis disorder
(MONDO_0019234)
Limited
PEX13
(HGNC:8855)
Zellweger spectrum disorders
(MONDO_0019609)
Strong
PEX14
(HGNC:8856)
Zellweger spectrum disorders
(MONDO_0019609)
Moderate
PEX16
(HGNC:8857)
peroxisome biogenesis disorder
(MONDO_0019234)
Strong
PEX16
(HGNC:8857)
Zellweger spectrum disorders
(MONDO_0019609)
Limited
PEX3
(HGNC:8858)
Zellweger spectrum disorders
(MONDO_0019609)
Limited
PEX6
(HGNC:8859)
peroxisome biogenesis disorder
(MONDO_0019234)
Strong
PEX6
(HGNC:8859)
Zellweger spectrum disorders
(MONDO_0019609)
Strong
PEX7
(HGNC:8860)
rhizomelic chondrodysplasia punctata type 1
(MONDO_0008972)
Definitive
PEX7
(HGNC:8860)
adult Refsum disease
(MONDO_0009958)
Limited
PEX7
(HGNC:8860)
peroxisome biogenesis disorder
(MONDO_0019234)
Definitive
ATRX
(HGNC:886)
alpha thalassemia-X-linked intellectual disability syndrome
(MONDO_0010519)
Definitive
ATRX
(HGNC:886)
intellectual disability-hypotonic facies syndrome, X-linked, 1
(MONDO_0010663)
Limited
KIF1A
(HGNC:888)
PEHO syndrome
(MONDO_0009841)
Strong
KIF1A
(HGNC:888)
hereditary spastic paraplegia 30
(MONDO_0012476)
Strong
PFN1
(HGNC:8881)
amyotrophic lateral sclerosis
(MONDO_0004976)
Strong
KIF1A
(HGNC:888)
hereditary sensory and autonomic neuropathy type 2
(MONDO_0019941)
Moderate
PGM3
(HGNC:8907)
immunodeficiency 23
(MONDO_0014353)
Definitive
KIF1A
(HGNC:888)
intellectual disability, autosomal dominant 9
(MONDO_0013656)
Strong
ACADL
(HGNC:88)
long chain acyl-CoA dehydrogenase deficiency
(MONDO_0020531)
Strong
PHGDH
(HGNC:8923)
PHGDH deficiency
(MONDO_0011152)
Strong
PHGDH
(HGNC:8923)
Neu-Laxova syndrome
(MONDO_0000179)
Definitive
PHKA2
(HGNC:8926)
glycogen storage disease IXa1
(MONDO_0010598)
Definitive
PHGDH
(HGNC:8923)
neurometabolic disorder due to serine deficiency
(MONDO_0018162)
Strong
PHKA1
(HGNC:8925)
glycogen storage disease IXd
(MONDO_0010362)
Moderate
PHKA2
(HGNC:8926)
glycogen storage disease due to liver phosphorylase kinase deficiency
(MONDO_0020693)
Definitive
PHKG2
(HGNC:8931)
glycogen storage disease IXc
(MONDO_0013091)
Strong
SERPINA1
(HGNC:8941)
cystic fibrosis
(MONDO_0009061)
Moderate
SERPINI1
(HGNC:8943)
familial encephalopathy with neuroserpin inclusion bodies
(MONDO_0011412)
Strong
PHKB
(HGNC:8927)
glycogen storage disease IXb
(MONDO_0009868)
Strong
AVP
(HGNC:894)
neurohypophyseal diabetes insipidus
(MONDO_0007450)
Moderate
SERPINA1
(HGNC:8941)
alpha 1-antitrypsin deficiency
(MONDO_0013282)
Definitive
PHKG2
(HGNC:8931)
glycogen storage disease due to liver phosphorylase kinase deficiency
(MONDO_0020693)
Strong
SERPINI1
(HGNC:8943)
progressive myoclonus epilepsy
(MONDO_0020074)
Moderate
SERPINB8
(HGNC:8952)
exfoliative ichthyosis
(MONDO_0017339)
Moderate
PHYH
(HGNC:8940)
adult Refsum disease
(MONDO_0009958)
Definitive
PIGA
(HGNC:8957)
multiple congenital anomalies-hypotonia-seizures syndrome 2
(MONDO_0010466)
Moderate
PIGA
(HGNC:8957)
ferro-cerebro-cutaneous syndrome
(MONDO_0018346)
Strong
PIGA
(HGNC:8957)
West syndrome
(MONDO_0018097)
Strong
AVPR1A
(HGNC:895)
autism spectrum disorder
(MONDO_0005258)
Limited
PIGL
(HGNC:8966)
hyperphosphatasia-intellectual disability syndrome
(MONDO_0016596)
Limited
PIGN
(HGNC:8967)
Fryns syndrome
(MONDO_0009253)
Strong
PIK3C2A
(HGNC:8971)
oculocerebrodental syndrome
(MONDO_0034145)
Moderate
PIK3CA
(HGNC:8975)
vascular malformation
(MONDO_0024291)
Strong
PIK3CA
(HGNC:8975)
hereditary breast carcinoma
(MONDO_0016419)
Limited
PIK3CA
(HGNC:8975)
Cowden disease
(MONDO_0016063)
Moderate
PIK3CA
(HGNC:8975)
megalencephaly-capillary malformation-polymicrogyria syndrome
(MONDO_0011240)
Definitive
PIK3CD
(HGNC:8977)
immunodeficiency 14
(MONDO_0014222)
Definitive
PIK3R1
(HGNC:8979)
immunodeficiency 36
(MONDO_0014453)
Strong
PIK3R1
(HGNC:8979)
SHORT syndrome
(MONDO_0010026)
Strong
PIK3R2
(HGNC:8980)
megalencephaly-polymicrogyria-postaxial polydactyly-hydrocephalus syndrome
(MONDO_0019375)
Strong
PIP5K1C
(HGNC:8996)
lethal congenital contracture syndrome 3
(MONDO_0012656)
Strong
PITX2
(HGNC:9005)
anterior segment dysgenesis 4
(MONDO_0007662)
Definitive
PITX2
(HGNC:9005)
Axenfeld-Rieger syndrome type 1
(MONDO_0008386)
Strong
PITX2
(HGNC:9005)
Peters anomaly
(MONDO_0011414)
Limited
PITX1
(HGNC:9004)
clubfoot
(MONDO_0007342)
Moderate
PITX2
(HGNC:9005)
aniridia
(MONDO_0019172)
Refuted
PITX2
(HGNC:9005)
Rieger anomaly
(MONDO_0019628)
Strong
PITX2
(HGNC:9005)
Axenfeld anomaly
(MONDO_0020368)
Strong
PKD1
(HGNC:9008)
polycystic kidney disease 1
(MONDO_0008263)
Definitive
PKD1
(HGNC:9008)
autosomal recessive polycystic kidney disease
(MONDO_0009889)
Limited
PKHD1
(HGNC:9016)
autosomal recessive polycystic kidney disease
(MONDO_0009889)
Definitive
PKD1
(HGNC:9008)
Caroli disease
(MONDO_0010913)
Limited
PKHD1
(HGNC:9016)
Caroli disease
(MONDO_0010913)
Moderate
PKP2
(HGNC:9024)
dilated cardiomyopathy
(MONDO_0005021)
Disputed
PKP2
(HGNC:9024)
Brugada syndrome
(MONDO_0015263)
Limited
PKP2
(HGNC:9024)
catecholaminergic polymorphic ventricular tachycardia
(MONDO_0017990)
Disputed
PKP2
(HGNC:9024)
left ventricular noncompaction
(MONDO_0018901)
Limited
PLA2G2A
(HGNC:9031)
colorectal cancer
(MONDO_0005575)
Limited
PLA2G6
(HGNC:9039)
autosomal recessive Parkinson disease 14
(MONDO_0013060)
Strong
AXIN2
(HGNC:904)
tooth agenesis
(MONDO_0005486)
Strong
AXIN2
(HGNC:904)
oligodontia-cancer predisposition syndrome
(MONDO_0012075)
Strong
AXIN2
(HGNC:904)
craniosynostosis
(MONDO_0015469)
Limited
PLCB4
(HGNC:9059)
auriculocondylar syndrome 2
(MONDO_0013845)
Strong
PLCB4
(HGNC:9059)
auriculocondylar syndrome
(MONDO_0000107)
Definitive
PLEC
(HGNC:9069)
aplasia cutis congenita
(MONDO_0007145)
Limited
PLEC
(HGNC:9069)
epidermolysis bullosa simplex 5B, with muscular dystrophy
(MONDO_0009181)
Strong
PLEC
(HGNC:9069)
autosomal recessive limb-girdle muscular dystrophy type 2Q
(MONDO_0013390)
Moderate
PLEC
(HGNC:9069)
congenital myasthenic syndrome
(MONDO_0018940)
Limited
PLEC
(HGNC:9069)
epidermolysis bullosa simplex
(MONDO_0017610)
Definitive
PLG
(HGNC:9071)
hypoplasminogenemia
(MONDO_0009009)
Moderate
SERPINF2
(HGNC:9075)
alpha-2-plasmin inhibitor deficiency
(MONDO_0009883)
Limited
PLOD2
(HGNC:9082)
Bruck syndrome 2
(MONDO_0012217)
Strong
PLN
(HGNC:9080)
arrhythmogenic right ventricular cardiomyopathy
(MONDO_0016587)
Moderate
PLOD2
(HGNC:9082)
Bruck syndrome
(MONDO_0017195)
Definitive
PLOD3
(HGNC:9083)
bone fragility with contractures, arterial rupture, and deafness
(MONDO_0012892)
Strong
PLXND1
(HGNC:9107)
Mobius syndrome
(MONDO_0008006)
Limited
PLP1
(HGNC:9086)
Pelizaeus-Merzbacher disease, classic form
(MONDO_0017222)
Strong
PLXND1
(HGNC:9107)
persistent truncus arteriosus
(MONDO_0018072)
Limited
PMP2
(HGNC:9117)
Charcot-Marie-Tooth disease
(MONDO_0015626)
Strong
PMP22
(HGNC:9118)
Charcot-Marie-Tooth disease type 1A
(MONDO_0007309)
Definitive
PMP22
(HGNC:9118)
Charcot-Marie-Tooth disease type 1E
(MONDO_0007311)
Limited
PMP22
(HGNC:9118)
Charcot-Marie-Tooth disease type 3
(MONDO_0007790)
Strong
PMP22
(HGNC:9118)
hereditary neuropathy with liability to pressure palsies
(MONDO_0008087)
Definitive
PMS1
(HGNC:9121)
Lynch syndrome
(MONDO_0005835)
Disputed
PMS2
(HGNC:9122)
Lynch syndrome
(MONDO_0005835)
Definitive
PMS2
(HGNC:9122)
breast cancer
(MONDO_0007254)
Disputed
PMS2
(HGNC:9122)
Muir-Torre syndrome
(MONDO_0008018)
Limited
PMS2
(HGNC:9122)
prostate cancer
(MONDO_0008315)
Limited
PMS2
(HGNC:9122)
ovarian cancer
(MONDO_0008170)
Limited
PMS2
(HGNC:9122)
hereditary breast carcinoma
(MONDO_0016419)
Limited
PMS2
(HGNC:9122)
mismatch repair cancer syndrome 1
(MONDO_0010159)
Definitive
EXOSC9
(HGNC:9137)
pontocerebellar hypoplasia type 1
(MONDO_0016396)
Strong
PRRX1
(HGNC:9142)
craniosynostosis
(MONDO_0015469)
Strong
B2M
(HGNC:914)
MHC class I deficiency
(MONDO_0011476)
Limited
PHOX2B
(HGNC:9143)
Haddad syndrome
(MONDO_0020493)
Strong
PNKD
(HGNC:9153)
Tourette syndrome
(MONDO_0007661)
Limited
PNKP
(HGNC:9154)
microcephaly, seizures, and developmental delay
(MONDO_0013254)
Definitive
PNKP
(HGNC:9154)
ataxia - oculomotor apraxia type 4
(MONDO_0014557)
Moderate
PNLIP
(HGNC:9155)
pancreatic triacylglycerol lipase deficiency
(MONDO_0013700)
Limited
POLE
(HGNC:9177)
facial dysmorphism-immunodeficiency-livedo-short stature syndrome
(MONDO_0014058)
Limited
POLA1
(HGNC:9173)
X-linked intellectual disability, van Esch type
(MONDO_0015601)
Strong
POLE
(HGNC:9177)
IMAGe syndrome
(MONDO_0013873)
Strong
POLD1
(HGNC:9175)
mandibular hypoplasia-deafness-progeroid syndrome
(MONDO_0014157)
Strong
POLA1
(HGNC:9173)
X-linked reticulate pigmentary disorder
(MONDO_0010523)
Limited
POLG
(HGNC:9179)
sensory ataxic neuropathy, dysarthria, and ophthalmoparesis
(MONDO_0011835)
Definitive
POLG
(HGNC:9179)
spinocerebellar ataxia with epilepsy
(MONDO_0016809)
Limited
POLG
(HGNC:9179)
autosomal recessive progressive external ophthalmoplegia
(MONDO_0016810)
Strong
POLE
(HGNC:9177)
intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, genital anomalies, and immunodeficiency
(MONDO_0032684)
Moderate
POLG
(HGNC:9179)
mitochondrial neurogastrointestinal encephalomyopathy
(MONDO_0017575)
Moderate
POLG
(HGNC:9179)
autosomal dominant progressive external ophthalmoplegia
(MONDO_0008003)
Strong
POLG
(HGNC:9179)
mitochondrial DNA depletion syndrome 4a
(MONDO_0008758)
Strong
POLG
(HGNC:9179)
Leigh syndrome
(MONDO_0009723)
Strong
POLG2
(HGNC:9180)
mitochondrial DNA depletion syndrome
(MONDO_0018158)
Limited
POLG2
(HGNC:9180)
autosomal dominant progressive external ophthalmoplegia
(MONDO_0008003)
Strong
POLG
(HGNC:9179)
recessive mitochondrial ataxia syndrome
(MONDO_0019791)
Strong
ACADSB
(HGNC:91)
2-methylbutyryl-CoA dehydrogenase deficiency
(MONDO_0012392)
Strong
POMC
(HGNC:9201)
inherited obesity
(MONDO_0019182)
Limited
POMT1
(HGNC:9202)
autosomal recessive limb-girdle muscular dystrophy type 2K
(MONDO_0012248)
Limited
POLH
(HGNC:9181)
xeroderma pigmentosum variant type
(MONDO_0010214)
Definitive
POMT1
(HGNC:9202)
muscular dystrophy-dystroglycanopathy, type A
(MONDO_0000171)
Definitive
PON1
(HGNC:9204)
amyotrophic lateral sclerosis
(MONDO_0004976)
Disputed
POMT1
(HGNC:9202)
muscle-eye-brain disease
(MONDO_0018939)
Strong
PON2
(HGNC:9205)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
POMC
(HGNC:9201)
obesity due to pro-opiomelanocortin deficiency
(MONDO_0012335)
Definitive
PON3
(HGNC:9206)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
POU3F3
(HGNC:9216)
snijders blok-fisher syndrome
(MONDO_0032830)
Strong
POU3F4
(HGNC:9217)
X-linked mixed hearing loss with perilymphatic gusher
(MONDO_0010576)
Strong
POU4F3
(HGNC:9220)
autosomal dominant nonsyndromic hearing loss 15
(MONDO_0011226)
Definitive
POU4F3
(HGNC:9220)
autosomal dominant nonsyndromic hearing loss
(MONDO_0019587)
Strong
B4GALT1
(HGNC:924)
B4GALT1-congenital disorder of glycosylation
(MONDO_0011772)
Moderate
PPARG
(HGNC:9236)
PPARG-related familial partial lipodystrophy
(MONDO_0011448)
Definitive
PPM1D
(HGNC:9277)
intellectual developmental disorder with gastrointestinal difficulties and high pain threshold
(MONDO_0044318)
Strong
PPP1CB
(HGNC:9282)
Noonan syndrome-like disorder with loose anagen hair
(MONDO_0011899)
Strong
PPM1D
(HGNC:9277)
hereditary breast carcinoma
(MONDO_0016419)
Limited
PDP1
(HGNC:9279)
pyruvate dehydrogenase phosphatase deficiency
(MONDO_0012120)
Moderate
B4GALT7
(HGNC:930)
Ehlers-Danlos syndrome, spondylodysplastic type, 1
(MONDO_0020682)
Strong
PPP1CB
(HGNC:9282)
Noonan syndrome-like disorder with loose anagen hair 2
(MONDO_0054588)
Strong
PPP2R2B
(HGNC:9305)
spinocerebellar ataxia type 12
(MONDO_0011439)
Definitive
PPP3CA
(HGNC:9314)
developmental and epileptic encephalopathy 91
(MONDO_0020630)
Strong
PRDM5
(HGNC:9349)
brittle cornea syndrome 2
(MONDO_0013605)
Strong
PPP3CC
(HGNC:9316)
schizophrenia
(MONDO_0005090)
Limited
PRDX3
(HGNC:9354)
spinocerebellar ataxia, autosomal recessive 32
(MONDO_0859245)
Moderate
PRDM5
(HGNC:9349)
Axenfeld-Rieger syndrome
(MONDO_0019187)
Limited
PPP2R5D
(HGNC:9312)
syndromic intellectual disability
(MONDO_0000508)
Definitive
PRDX1
(HGNC:9352)
methylmalonic aciduria and homocystinuria type cblC
(MONDO_0010184)
Moderate
PRF1
(HGNC:9360)
hereditary hemophagocytic lymphohistiocytosis
(MONDO_0015541)
Definitive
SLC26A5
(HGNC:9359)
autosomal recessive nonsyndromic hearing loss 61
(MONDO_0013471)
Moderate
PPP2R5D
(HGNC:9312)
Hogue-Janssens syndrome 1
(MONDO_0014602)
Strong
PRKCD
(HGNC:9399)
common variable immunodeficiency
(MONDO_0015517)
Limited
ZMYND8
(HGNC:9397)
neurodevelopmental disorder
(MONDO_0700092)
Strong
PRKRA
(HGNC:9438)
dystonia 16
(MONDO_0012789)
Strong
BAG3
(HGNC:939)
distal hereditary motor neuropathy
(MONDO_0018894)
Limited
DNAJC3
(HGNC:9439)
type 2 diabetes mellitus
(MONDO_0005148)
Limited
PRNP
(HGNC:9449)
inherited Creutzfeldt-Jakob disease
(MONDO_0007403)
Definitive
PROC
(HGNC:9451)
hereditary thrombophilia due to congenital protein C deficiency
(MONDO_0019145)
Definitive
PRNP
(HGNC:9449)
Gerstmann-Straussler-Scheinker syndrome
(MONDO_0007656)
Strong
PRNP
(HGNC:9449)
fatal familial insomnia
(MONDO_0010808)
Definitive
PRODH
(HGNC:9453)
hyperprolinemia type 1
(MONDO_0009400)
Strong
PROM1
(HGNC:9454)
retinitis pigmentosa
(MONDO_0019200)
Moderate
PROM1
(HGNC:9454)
cone-rod dystrophy
(MONDO_0015993)
Definitive
PROM1
(HGNC:9454)
inherited retinal dystrophy
(MONDO_0019118)
Strong
PROM1
(HGNC:9454)
Stargardt disease
(MONDO_0019353)
Moderate
PLPBP
(HGNC:9457)
pyridoxine-dependent epilepsy
(MONDO_0009945)
Strong
PROP1
(HGNC:9455)
combined pituitary hormone deficiencies, genetic form
(MONDO_0013099)
Definitive
PROS1
(HGNC:9456)
hereditary thrombophilia due to congenital protein S deficiency
(MONDO_0019144)
Definitive
PRKAG2
(HGNC:9386)
lethal congenital glycogen storage disease of heart
(MONDO_0009867)
Limited
PRKACB
(HGNC:9381)
Ellis-van Creveld syndrome
(MONDO_0009162)
Limited
PRKAR1A
(HGNC:9388)
primary pigmented nodular adrenocortical disease
(MONDO_0015999)
Definitive
PRKAR1A
(HGNC:9388)
acrodysostosis
(MONDO_0019797)
Definitive
PRKAG2
(HGNC:9386)
hypertrophic cardiomyopathy
(MONDO_0005045)
Definitive
PRPS1
(HGNC:9462)
phosphoribosylpyrophosphate synthetase superactivity
(MONDO_0010395)
Moderate
PRKAR1B
(HGNC:9390)
Marbach-Schaaf neurodevelopmental syndrome
(MONDO_0859214)
Strong
PRPS1
(HGNC:9462)
hearing loss, X-linked 1
(MONDO_0010577)
Definitive
PRSS12
(HGNC:9477)
autosomal recessive non-syndromic intellectual disability
(MONDO_0019502)
Limited
PRSS1
(HGNC:9475)
hereditary chronic pancreatitis
(MONDO_0008185)
Definitive
LONP1
(HGNC:9479)
congenital diaphragmatic hernia
(MONDO_0005711)
Strong
PRPH
(HGNC:9461)
amyotrophic lateral sclerosis
(MONDO_0004976)
Limited
LONP1
(HGNC:9479)
Leigh syndrome
(MONDO_0009723)
Limited
HTRA1
(HGNC:9476)
cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 2
(MONDO_0014768)
Strong
PSEN1
(HGNC:9508)
dilated cardiomyopathy
(MONDO_0005021)
Limited
PSEN1
(HGNC:9508)
Pick disease
(MONDO_0008243)
Limited
LONP1
(HGNC:9479)
CODAS syndrome
(MONDO_0010879)
Definitive
PSEN2
(HGNC:9509)
dilated cardiomyopathy
(MONDO_0005021)
Limited
BARD1
(HGNC:952)
breast cancer
(MONDO_0007254)
Moderate
PRKAG2
(HGNC:9386)
Wolff-Parkinson-White syndrome
(MONDO_0008685)
Definitive
NKX3-2
(HGNC:951)
spondylo-megaepiphyseal-metaphyseal dysplasia
(MONDO_0013228)
Limited
PRKAR1A
(HGNC:9388)
Carney complex
(MONDO_0015285)
Definitive
PRF1
(HGNC:9360)
familial hemophagocytic lymphohistiocytosis 2
(MONDO_0011337)
Definitive
BARD1
(HGNC:952)
hereditary breast carcinoma
(MONDO_0016419)
Moderate
BARD1
(HGNC:952)
hereditary nonpolyposis colon cancer
(MONDO_0018630)
Limited
PSMB8
(HGNC:9545)
proteosome-associated autoinflammatory syndrome
(MONDO_0009726)
Definitive
PSMC3
(HGNC:9549)
neurodevelopmental disorder
(MONDO_0700092)
Strong
PSMC5
(HGNC:9552)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
PSMD12
(HGNC:9557)
Stankiewicz-Isidor syndrome
(MONDO_0054591)
Strong
PSTPIP1
(HGNC:9580)
autoinflammatory syndrome
(MONDO_0019751)
Disputed
PTCH1
(HGNC:9585)
holoprosencephaly
(MONDO_0016296)
Limited
PSTPIP1
(HGNC:9580)
recurrent infections-inflammatory syndrome due to zinc metabolism disorder syndrome
(MONDO_0016676)
Definitive
PSTPIP1
(HGNC:9580)
pyogenic arthritis-pyoderma gangrenosum-acne syndrome
(MONDO_0011462)
Strong
PTCH1
(HGNC:9585)
nevoid basal cell carcinoma syndrome
(MONDO_0007187)
Definitive
PTEN
(HGNC:9588)
renal cell carcinoma
(MONDO_0005086)
Moderate
PTDSS1
(HGNC:9587)
Lenz-Majewski hyperostotic dwarfism
(MONDO_0007892)
Definitive
PTCH2
(HGNC:9586)
nevoid basal cell carcinoma syndrome
(MONDO_0007187)
Refuted
PTEN
(HGNC:9588)
leiomyosarcoma
(MONDO_0005058)
Limited
PTEN
(HGNC:9588)
Cowden disease
(MONDO_0016063)
Definitive
PTEN
(HGNC:9588)
Proteus-like syndrome
(MONDO_0017571)
Definitive
PTEN
(HGNC:9588)
PTEN hamartoma tumor syndrome
(MONDO_0017623)
Definitive
PTEN
(HGNC:9588)
Bannayan-Riley-Ruvalcaba syndrome
(MONDO_0007924)
Definitive
SLC33A1
(HGNC:95)
Huppke-Brendel syndrome
(MONDO_0013772)
Strong
PTH1R
(HGNC:9608)
metaphyseal chondrodysplasia, Jansen type
(MONDO_0007982)
Strong
PTH1R
(HGNC:9608)
chondrodysplasia Blomstrand type
(MONDO_0008970)
Strong
PTH1R
(HGNC:9608)
primary failure of tooth eruption
(MONDO_0007434)
Definitive
HACD1
(HGNC:9639)
congenital myopathy
(MONDO_0019952)
Strong
PTEN
(HGNC:9588)
Lhermitte-Duclos disease
(MONDO_0019002)
Strong
PTH1R
(HGNC:9608)
Eiken syndrome
(MONDO_0010803)
Strong
PTHLH
(HGNC:9607)
brachydactyly type E
(MONDO_0019677)
Strong
PTPN11
(HGNC:9644)
Costello syndrome
(MONDO_0009026)
Refuted
PTPN11
(HGNC:9644)
metachondromatosis
(MONDO_0007979)
Strong
BAZ2B
(HGNC:963)
neurodevelopmental disorder
(MONDO_0700092)
Moderate
PTPN11
(HGNC:9644)
Noonan syndrome with multiple lentigines
(MONDO_0007893)
Definitive
PTPN11
(HGNC:9644)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Limited
PTPN11
(HGNC:9644)
Noonan syndrome
(MONDO_0018997)
Definitive
PTPN22
(HGNC:9652)
systemic lupus erythematosus
(MONDO_0007915)
Moderate
PTPN22
(HGNC:9652)
rheumatoid arthritis
(MONDO_0008383)
Definitive
PTPRJ
(HGNC:9673)
colorectal cancer
(MONDO_0005575)
Limited
BBS2
(HGNC:967)
ciliopathy
(MONDO_0005308)
Limited
PTPRQ
(HGNC:9679)
autosomal recessive nonsyndromic hearing loss 84A
(MONDO_0013249)
Strong
BBS2
(HGNC:967)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
BBS2
(HGNC:967)
retinitis pigmentosa
(MONDO_0019200)
Limited
PTS
(HGNC:9689)
BH4-deficient hyperphenylalaninemia A
(MONDO_0009863)
Definitive
BBS4
(HGNC:969)
Bardet-Biedl syndrome
(MONDO_0015229)
Moderate
BBS5
(HGNC:970)
Bardet-Biedl syndrome 5
(MONDO_0014434)
Moderate
BBS5
(HGNC:970)
Bardet-Biedl syndrome
(MONDO_0015229)
Strong
PEX19
(HGNC:9713)
peroxisome biogenesis disorder
(MONDO_0019234)
Moderate
PEX2
(HGNC:9717)
peroxisome biogenesis disorder
(MONDO_0019234)
Definitive
PEX19
(HGNC:9713)
Zellweger spectrum disorders
(MONDO_0019609)
Limited
PEX2
(HGNC:9717)
Zellweger spectrum disorders
(MONDO_0019609)
Definitive
PEX5
(HGNC:9719)
rhizomelic chondrodysplasia punctata type 5
(MONDO_0014743)
Strong
PEX5
(HGNC:9719)
peroxisome biogenesis disorder
(MONDO_0019234)
Definitive
PYCR1
(HGNC:9721)
geroderma osteodysplastica
(MONDO_0009271)
Limited
PYCR1
(HGNC:9721)
autosomal recessive cutis laxa type 2B
(MONDO_0013051)
Strong
ALDH18A1
(HGNC:9722)
ALDH18A1-related de Barsy syndrome
(MONDO_0009053)
Strong
ALDH18A1
(HGNC:9722)
hereditary spastic paraplegia 9A
(MONDO_0011006)
Strong
ALDH18A1
(HGNC:9722)
autosomal recessive complex spastic paraplegia type 9B
(MONDO_0014702)
Strong
ALDH18A1
(HGNC:9722)
cutis laxa, autosomal dominant 3
(MONDO_0014706)
Moderate
PYGL
(HGNC:9725)
glycogen storage disease VI
(MONDO_0009294)
Definitive
RAB28
(HGNC:9768)
cone-rod dystrophy
(MONDO_0015993)
Strong
RAB7A
(HGNC:9788)
Charcot-Marie-Tooth disease type 2B
(MONDO_0010949)
Definitive
RAC1
(HGNC:9801)
intellectual disability, autosomal dominant 48
(MONDO_0030913)
Strong
RAD50
(HGNC:9816)
Nijmegen breakage syndrome-like disorder
(MONDO_0013118)
Limited
RAD50
(HGNC:9816)
hereditary breast carcinoma
(MONDO_0016419)
Limited
RAB7A
(HGNC:9788)
Charcot-Marie-Tooth disease type 2
(MONDO_0018993)
Strong
RAD51
(HGNC:9817)
hereditary breast carcinoma
(MONDO_0016419)
Limited
RAD51
(HGNC:9817)
Fanconi anemia
(MONDO_0019391)
Limited
RAD51
(HGNC:9817)
familial congenital mirror movements
(MONDO_0016558)
Limited
RAD51C
(HGNC:9820)
Fanconi anemia complementation group O
(MONDO_0013248)
Limited
RAD51C
(HGNC:9820)
hereditary breast ovarian cancer syndrome
(MONDO_0003582)
Definitive
RAD51C
(HGNC:9820)
hereditary breast carcinoma
(MONDO_0016419)
Strong
RAD51D
(HGNC:9823)
hereditary breast ovarian cancer syndrome
(MONDO_0003582)
Strong
RAD51C
(HGNC:9820)
Fanconi anemia
(MONDO_0019391)
Moderate
RAF1
(HGNC:9829)
Noonan syndrome with multiple lentigines
(MONDO_0007893)
Strong
RAF1
(HGNC:9829)
Costello syndrome
(MONDO_0009026)
Limited
RAD51D
(HGNC:9823)
hereditary breast carcinoma
(MONDO_0016419)
Moderate
RAF1
(HGNC:9829)
LEOPARD syndrome 2
(MONDO_0012691)
Moderate
RAF1
(HGNC:9829)
cardiofaciocutaneous syndrome
(MONDO_0015280)
Limited
RAF1
(HGNC:9829)
Noonan syndrome
(MONDO_0018997)
Definitive
RAG1
(HGNC:9831)
immunodeficiency disease
(MONDO_0021094)
Definitive
RAG2
(HGNC:9832)
Omenn syndrome
(MONDO_0011338)
Definitive
RAI1
(HGNC:9834)
Potocki-Lupski syndrome
(MONDO_0012574)
Strong
BCHE
(HGNC:983)
butyrylcholinesterase deficiency
(MONDO_0015270)
Definitive
RANBP2
(HGNC:9848)
familial acute necrotizing encephalopathy
(MONDO_0011953)
Moderate
RAPSN
(HGNC:9863)
fetal akinesia deformation sequence 1
(MONDO_0100101)
Moderate
RAPSN
(HGNC:9863)
postsynaptic congenital myasthenic syndrome
(MONDO_0020344)
Definitive
RARB
(HGNC:9865)
Matthew-Wood syndrome
(MONDO_0011010)
Moderate
BCKDHA
(HGNC:986)
maple syrup urine disease
(MONDO_0009563)
Definitive
RARB
(HGNC:9865)
microphthalmia, syndromic 12
(MONDO_0014229)
Strong
RASA2
(HGNC:9872)
Noonan syndrome
(MONDO_0018997)
Limited
RASAL1
(HGNC:9873)
breast cancer
(MONDO_0007254)
Limited
RB1
(HGNC:9884)
melanoma
(MONDO_0005105)
Limited
RB1
(HGNC:9884)
hereditary retinoblastoma
(MONDO_0018160)
Definitive
RB1
(HGNC:9884)
retinoblastoma
(MONDO_0008380)
Definitive
RBP3
(HGNC:9921)
retinitis pigmentosa
(MONDO_0019200)
Moderate
KDM5A
(HGNC:9886)
congenital heart disease
(MONDO_0005453)
Limited
RBBP8
(HGNC:9891)
Jawad syndrome
(MONDO_0009622)
Strong
RBBP8
(HGNC:9891)
Seckel syndrome
(MONDO_0019342)
Strong
RBM8A
(HGNC:9905)
thrombocytopenia-absent radius syndrome
(MONDO_0010121)
Definitive
PRPH2
(HGNC:9942)
adult-onset foveomacular vitelliform dystrophy
(MONDO_0011979)
Limited
OPN1LW
(HGNC:9936)
blue cone monochromacy
(MONDO_0010563)
Definitive
PRPH2
(HGNC:9942)
central areolar choroidal dystrophy
(MONDO_0008982)
Strong
PRPH2
(HGNC:9942)
fundus albipunctatus
(MONDO_0007639)
Limited
PRPH2
(HGNC:9942)
retinitis punctata albescens
(MONDO_0018877)
Limited
PRPH2
(HGNC:9942)
Leber congenital amaurosis
(MONDO_0018998)
Limited
PRPH2
(HGNC:9942)
cone-rod dystrophy
(MONDO_0015993)
Strong
PRPH2
(HGNC:9942)
inherited retinal dystrophy
(MONDO_0019118)
Definitive
PRPH2
(HGNC:9942)
retinitis pigmentosa
(MONDO_0019200)
Definitive
PRPH2
(HGNC:9942)
multifocal pattern dystrophy simulating fundus flavimaculatus
(MONDO_0020382)
Limited
RECQL
(HGNC:9948)
breast cancer
(MONDO_0007254)
Disputed
RECQL
(HGNC:9948)
hereditary breast carcinoma
(MONDO_0016419)
Strong
RECQL4
(HGNC:9949)
Baller-Gerold syndrome
(MONDO_0009039)
Strong
RECQL4
(HGNC:9949)
osteosarcoma
(MONDO_0009807)
Strong
RECQL4
(HGNC:9949)
rapadilino syndrome
(MONDO_0009955)
Limited
RECQL4
(HGNC:9949)
Rothmund-Thomson syndrome
(MONDO_0010002)
Definitive
RECQL5
(HGNC:9950)
breast cancer
(MONDO_0007254)
Limited
RECQL5
(HGNC:9950)
coronary artery disorder
(MONDO_0005010)
Limited
RELN
(HGNC:9957)
ankylosing spondylitis
(MONDO_0005306)
Limited
RELN
(HGNC:9957)
autosomal dominant epilepsy with auditory features
(MONDO_0010898)
Strong
DPF2
(HGNC:9964)
Coffin-Siris syndrome
(MONDO_0015452)
Strong
RELN
(HGNC:9957)
lissencephaly with cerebellar hypoplasia
(MONDO_0019450)
Definitive
RERE
(HGNC:9965)
neurodevelopmental disorder with or without anomalies of the brain, eye, or heart
(MONDO_0014857)
Strong
REST
(HGNC:9966)
hereditary gingival fibromatosis
(MONDO_0016070)
Strong
RET
(HGNC:9967)
Hirschsprung disease, susceptibility to, 1
(MONDO_0007723)
Definitive
RET
(HGNC:9967)
multiple endocrine neoplasia type 2B
(MONDO_0008082)
Definitive
RET
(HGNC:9967)
familial medullary thyroid carcinoma
(MONDO_0007958)
Definitive
RET
(HGNC:9967)
pheochromocytoma
(MONDO_0008233)
Definitive
RET
(HGNC:9967)
multiple endocrine neoplasia type 2A
(MONDO_0008234)
Definitive
RET
(HGNC:9967)
renal agenesis, unilateral
(MONDO_0019636)
Limited
REV3L
(HGNC:9968)
Mobius syndrome
(MONDO_0008006)
Limited
RET
(HGNC:9967)
Hirschsprung disease
(MONDO_0018309)
Definitive
RFC1
(HGNC:9969)
cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome
(MONDO_0044720)
Strong
RFX2
(HGNC:9983)
cerebral palsy
(MONDO_0006497)
Limited
RFX3
(HGNC:9984)
autism spectrum disorder
(MONDO_0005258)
Moderate
RFX5
(HGNC:9986)
MHC class II deficiency
(MONDO_0008855)
Definitive
RFXAP
(HGNC:9988)
MHC class II deficiency
(MONDO_0008855)
Strong
RFXANK
(HGNC:9987)
MHC class II deficiency
(MONDO_0008855)
Definitive