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Fusions

Summaries of gene fusions and their clinical relevance.

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Fusion Disease Driver/Marker Power Therapeutic Actionability Prognostic Impact Diagnostic Specificity Monitoring Utility Actions
UBTF–ATXN7L3
(HGNC:12511, HGNC:25416)
MONDO:0004947
(MONDO:0004947)
 strong moderate strong strong weak
TYK2–NPM1
(HGNC:12440, HGNC:7910)
MONDO:0015758
(MONDO:0015758)
 moderate moderate weak strong weak
TSC2–PKD1
(HGNC:12363, HGNC:9008)
MONDO:0001734
(MONDO:0001734)
 moderate weak weak strong weak
TYK2–MYB
(HGNC:12440, HGNC:7545)
MONDO:0004967
(MONDO:0004967)
 strong strong moderate strong weak
TRPS1–PLAG1
(HGNC:12340, HGNC:9045)
strong weak weak strong weak
TRIP11–FLT3
(HGNC:12305, HGNC:3765)
MONDO:0015687
(MONDO:0015687)
 moderate weak moderate moderate weak
TRAF1–ALK
(HGNC:12031, HGNC:427)
MONDO:0020325
(MONDO:0020325)
 strong strong moderate strong weak
TRB–NOTCH1
(HGNC:12155, HGNC:7881)
moderate moderate moderate moderate weak
TPR–FGFR1
(HGNC:12017, HGNC:3688)
MONDO:0013296
(MONDO:0013296)
 strong strong moderate strong weak
TPR–NTRK1
(HGNC:12017, HGNC:8031)
MONDO:0002616
(MONDO:0002616)
 strong strong moderate strong weak
TPM4–ALK
(HGNC:12013, HGNC:427)
anaplastic large cell lymphoma
(MONDO_0020325)
 strong strong moderate moderate weak
TPM4–NTRK1
(HGNC:12013, HGNC:8031)
moderate strong moderate moderate weak
NUP98–TOP1
(HGNC:8068, HGNC:11986)
MONDO:0018874
(MONDO:0018874)
 strong weak moderate moderate weak
TP53–FXR2
(HGNC:11998, HGNC:4024)
MONDO:0007256
(MONDO:0007256)
 moderate weak weak moderate weak
TPM3–ALK
(HGNC:12012, HGNC:427)
MONDO:0015798
(MONDO:0015798)
 strong strong moderate strong moderate
TNS1–ALK
(HGNC:11973, HGNC:427)
MONDO:0001572
(MONDO:0001572)
 strong strong moderate strong moderate
TNRC18–RARA
(HGNC:11962, HGNC:9864)
MONDO:0006052
(MONDO:0006052)
 moderate moderate moderate moderate weak
MED12–PRDM10
(HGNC:11957, HGNC:13995)
Partington syndrome
(MONDO_0010654)
 moderate weak weak strong weak
EP400–PHF1
(HGNC:11958, HGNC:8919)
MONDO:0006330
(MONDO:0006330)
 weak weak weak strong weak
ZNF384–EP300
(HGNC:11955, HGNC:3373)
precursor B-cell acute lymphoblastic leukemia
(MONDO_0020511)
 strong strong moderate strong weak
Showing 381–400 of 512