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Fusions

Summaries of gene fusions and their clinical relevance.

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Fusion Disease Driver/Marker Power Therapeutic Actionability Prognostic Impact Diagnostic Specificity Monitoring Utility Actions
BRAF–MKRN1
(HGNC:1097, HGNC:7112)
MONDO:0006468
(MONDO:0006468)
 moderate moderate weak moderate weak
BRAF–AKAP9
(HGNC:1097, HGNC:379)
thyroid cancer
(MONDO_0002108)
 strong strong moderate strong weak
BRAF–FGFR1
(HGNC:1097, HGNC:3688)
MONDO:0016695
(MONDO:0016695)
 weak weak moderate weak weak
SLC25A1–FUBP1
(HGNC:10979, HGNC:4004)
glioma
(MONDO_0021042)
 weak weak weak weak weak
BRAF–KIAA1549
(HGNC:1097, HGNC:22219)
MONDO:0016691
(MONDO:0016691)
 strong strong strong strong weak
AGK–BRAF
(HGNC:21869, HGNC:1097)
thyroid cancer
(MONDO_0002108)
 strong strong moderate strong weak
BRAF–AGAP3
(HGNC:1097, HGNC:16923)
melanoma
(MONDO_0005105)
 strong strong moderate moderate weak
SLC25A1–DUX4
(HGNC:10979, HGNC:50800)
soft tissue sarcoma
(MONDO_0018078)
 strong strong strong strong weak
SLC25A1–CREB1
(HGNC:10979, HGNC:2345)
MONDO:0002616
(MONDO:0002616)
 weak weak weak weak weak
SLC25A1–LEUTX
(HGNC:10979, HGNC:31953)
MONDO:0016982
(MONDO:0016982)
 strong moderate moderate strong weak
SLC25A1–EWSR1
(HGNC:10979, HGNC:3508)
Ewing sarcoma
(MONDO_0012817)
 weak weak weak weak weak
SLC25A1–NUTM2A
(HGNC:10979, HGNC:23438)
MONDO:0018874
(MONDO:0018874)
 weak weak weak weak weak
ROS1–SDC4
(HGNC:10261, HGNC:10661)
non-small cell lung carcinoma
(MONDO_0005233)
 strong strong moderate strong weak
ROS1–CD74
(HGNC:10261, HGNC:1697)
MONDO:0008903
(MONDO:0008903)
 strong strong moderate strong moderate
RUNX1–AKR1C4
(HGNC:10471, HGNC:387)
MONDO:0018874
(MONDO:0018874)
 weak weak weak weak weak
SLC25A1–BCOR
(HGNC:10979, HGNC:20893)
MONDO:0012817
(MONDO:0012817)
 weak weak weak weak weak
RUNX1–ETV6
(HGNC:10471, HGNC:3495)
MONDO:0004967
(MONDO:0004967)
 strong moderate strong strong moderate
BCR–NTRK2
(HGNC:1014, HGNC:8032)
MONDO:0100342
(MONDO:0100342)
 strong strong moderate strong weak
STIL–TAL1
(HGNC:10879, HGNC:11556)
MONDO:0004963
(MONDO:0004963)
 strong moderate moderate strong weak
RUNX1–MECOM
(HGNC:10471, HGNC:3498)
MONDO:0018874
(MONDO:0018874)
 strong moderate strong moderate weak
Showing 461–480 of 512