Fusions

Summaries of gene fusions and their clinical relevance.

Back to Open Access Summaries
Need updated, customized, evidence‑backed summaries? Get it from the leaders in AI‑powered, evidence‑backed summaries provider.
Contact us
Fusion Disease Driver/Marker Power Therapeutic Actionability Prognostic Impact Diagnostic Specificity Monitoring Utility Actions
EWSR1–FUS
(HGNC:3508, HGNC:4010)
weak weak weak weak weak
ETV6–PDGFRB
(HGNC:3495, HGNC:8804)
MONDO:0020311
(MONDO:0020311)
 strong strong moderate strong weak
ETV6–NTRK2
(HGNC:3495, HGNC:8032)
MONDO:0009693
(MONDO:0009693)
 moderate moderate weak moderate weak
ETV6–NTRK3
(HGNC:3495, HGNC:8033)
MONDO:0004557
(MONDO:0004557)
 strong strong moderate strong weak
ETV6–ABL1
(HGNC:3495, HGNC:76)
MONDO:0000870
(MONDO:0000870)
 strong strong moderate moderate weak
ETV6–ARNT
(HGNC:3495, HGNC:700)
acute myeloid leukemia with minimal differentiation
(MONDO_0005223)
 strong weak weak moderate weak
ETV6–NCOA2
(HGNC:3495, HGNC:7669)
MONDO:0000870
(MONDO:0000870)
 strong moderate moderate strong weak
ETV6–JAK2
(HGNC:3495, HGNC:6192)
MONDO:0004967
(MONDO:0004967)
 strong strong moderate strong weak
ETV6–LYN
(HGNC:3495, HGNC:6735)
MONDO:0018874
(MONDO:0018874)
 moderate weak weak moderate weak
ETV6–FRK
(HGNC:3495, HGNC:3955)
MONDO:0018874
(MONDO:0018874)
 moderate moderate weak moderate weak
ETV6–FLT3
(HGNC:3495, HGNC:3765)
acute lymphoblastic leukemia
(MONDO_0004967)
 strong strong moderate strong weak
ETV6–IGH
(HGNC:3495, HGNC:5477)
MONDO:0002571
(MONDO:0002571)
 moderate weak weak moderate weak
ETV6–MNX1
(HGNC:3495, HGNC:4979)
MONDO:0018874
(MONDO:0018874)
 strong moderate strong strong weak
ETV6–FGFR3
(HGNC:3495, HGNC:3690)
MONDO:0018874
(MONDO:0018874)
 strong strong moderate moderate weak
ETV6–MECOM
(HGNC:3495, HGNC:3498)
MONDO:0018874
(MONDO:0018874)
 strong strong strong moderate weak
ETV1–FOXP1
(HGNC:3490, HGNC:3823)
MONDO:0008315
(MONDO:0008315)
 moderate weak weak moderate weak
AHRR–NCOA2
(HGNC:346, HGNC:7669)
MONDO:0016238
(MONDO:0016238)
 strong weak weak strong weak
ETV3–NCOA2
(HGNC:3492, HGNC:7669)
indeterminate dendritic cell tumor
(MONDO_0015538)
 strong strong moderate strong weak
ERBB2–GRB7
(HGNC:3430, HGNC:4567)
MONDO:0006244
(MONDO:0006244)
 moderate weak weak moderate weak
ESR1–NCOA3
(HGNC:3467, HGNC:7670)
MONDO:0005636
(MONDO:0005636)
 weak weak weak weak weak
Showing 141–160 of 512